pro-diazepam has been researched along with atropine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baubichon, D; Blanchet, G; Brochier, G; Clarencon, D; Galonnier, M; Lallement, G; Mestries, JC | 1 |
| Blanchet, G; Carlsson Bratt, I; Clair, P; Granelli, I; Wiberg, K | 1 |
| Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Jourdil, N; Lallement, G; Peoc'h, M; Renault, F | 1 |
| Breton, P; Buée, J; Calvet, JH; Christin, D; Delamanche, S; Taysse, L | 1 |
| Aas, P; Enger, S; Myhrer, T | 1 |
| Bellier, B; Breton, P; Daulon, S; Delamanche, S; Taysse, L | 1 |
| Armstrong, S; Mumford, H; Price, M; Scott, L; Wetherell, J | 1 |
| Abbara, C; Bardot, I; Clair, P; Comets, E; Diquet, B; Lallement, G; Rousseau, JM; Turcant, A | 1 |
| Abbara, C; Bardot, I; Diquet, B; Ferec, S; Lallement, G; Lelièvre, B; Rousseau, JM; Turcant, A | 1 |
| Bird, M; Docx, CJ; Fairhall, SJ; Flint, DP; Green, AC; Poole, SJC; Price, ME; Rice, H; Tattersall, JEH; Timperley, CM; Whiley, L | 1 |
| Emery, ER; Green, AC; Laws, TR; Mann, TM; McColm, RR; Perrott, RL; Price, ME; Rice, H; Tattersall, JEH; Whitmore, CL | 1 |
2 trial(s) available for pro-diazepam and atropine
| Article | Year |
|---|---|
Bioavailability of diazepam after intramuscular injection of its water-soluble prodrug alone or with atropine-pralidoxime in healthy volunteers.
Topics: Adolescent; Adult; Area Under Curve; Atropine; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Diazepam; Dipeptides; Drug Combinations; Humans; Injections, Intramuscular; Male; Middle Aged; Pralidoxime Compounds; Prodrugs; Solubility; Tandem Mass Spectrometry; Water | 2009 |
Pharmacokinetic analysis of pralidoxime after its intramuscular injection alone or in combination with atropine-avizafone in healthy volunteers.
Topics: Adolescent; Adult; Atropine; Dipeptides; Drug Combinations; Drug Interactions; Humans; Injections, Intramuscular; Male; Middle Aged; Models, Statistical; Pralidoxime Compounds | 2010 |
9 other study(ies) available for pro-diazepam and atropine
| Article | Year |
|---|---|
Efficacy of atropine/pralidoxime/diazepam or atropine/HI-6/prodiazepam in primates intoxicated by soman.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electrocardiography; Electroencephalography; Macaca fascicularis; Male; Oximes; Poisoning; Pralidoxime Compounds; Prodrugs; Pyridinium Compounds; Soman | 1997 |
Stability study of a new antidote drug combination (Atropine-HI-6-Prodiazepam) for treatment of organophosphate poisoning.
Topics: Antidotes; Atropine; Cholinergic Antagonists; Cholinesterase Reactivators; Chromatography, High Pressure Liquid; Diazepam; Dipeptides; Drug Combinations; Drug Stability; Organophosphate Poisoning; Oximes; Prodrugs; Pyridinium Compounds | 2000 |
Compared efficacy of diazepam or avizafone to prevent soman-induced electroencephalographic disturbances and neuropathology in primates: relationship to plasmatic benzodiazepine pharmacokinetics.
Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electroencephalography; Macaca fascicularis; Male; Pralidoxime Compounds; Soman | 2000 |
Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose.
Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Interactions; Electroencephalography; Guinea Pigs; Histocytochemistry; Muscarinic Antagonists; Nervous System Diseases; Pralidoxime Compounds; Prodrugs; Pyridostigmine Bromide; Respiratory Insufficiency; Sarin; Seizures | 2003 |
Efficacy of immediate and subsequent therapies against soman-induced seizures and lethality in rats.
Topics: Animals; Anticonvulsants; Atropine; Brain; Diazepam; Dipeptides; Drug Combinations; Lethal Dose 50; Male; Oximes; Pentobarbital; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman | 2006 |
Protection against soman-induced neuropathology and respiratory failure: a comparison of the efficacy of diazepam and avizafone in guinea pig.
Topics: Animals; Anticonvulsants; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Dipeptides; Electroencephalography; Guinea Pigs; Neuroprotective Agents; Neurotoxicity Syndromes; Respiratory Insufficiency; Soman | 2006 |
Development of next generation medical countermeasures to nerve agent poisoning.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Dipeptides; Disease Models, Animal; Drug Therapy, Combination; Guinea Pigs; Ileal Diseases; Intussusception; Lethal Dose 50; Male; Neurotoxicity Syndromes; Oximes; Physostigmine; Pyridinium Compounds; Scopolamine Derivatives; Soman; Time Factors | 2007 |
Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig.
Topics: Animals; Anticonvulsants; Antidotes; Atropine; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; Lethal Dose 50; Male; Muscarinic Antagonists; Nerve Agents; Nicotinic Antagonists; Poisoning; Pyridinium Compounds; Soman | 2016 |
Bioscavenger is effective as a delayed therapeutic intervention following percutaneous VX poisoning in the guinea-pig.
Topics: Administration, Cutaneous; Animals; Antidotes; Atropine; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Reactivators; Cholinesterases; Dipeptides; Guinea Pigs; Male; Muscarinic Antagonists; Nerve Agents; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds; Time-to-Treatment; Toxicokinetics | 2018 |