primaquine has been researched along with mefloquine in 93 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (10.75) | 18.7374 |
| 1990's | 26 (27.96) | 18.2507 |
| 2000's | 24 (25.81) | 29.6817 |
| 2010's | 32 (34.41) | 24.3611 |
| 2020's | 1 (1.08) | 2.80 |
| Authors | Studies |
|---|---|
| Fidock, DA; Flannery, EL; Winzeler, EA | 1 |
| Avery, VM; Sykes, ML | 1 |
| Albuquerque, IS; Burojević, J; D'Alessandro, S; Djurković-Djaković, O; Konstantinović, J; Machado, M; Pecic, S; Prudêncio, M; Sciotti, RJ; Šolaja, BA; Srbljanović, J; Štajner, T; Taramelli, D; Terzić, N; Tot, M; Verbić, T; Zlatović, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bane, CE; Black, C; Butler, K; Caridha, D; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Huezo, SJ; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Nolan, C; Olmeda, R; Potter, B; Pou, S; Rasmussen, SA; Read, L; Riscoe, MK; Roncal, N; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Stephens, MT; Tan, JC; Vesely, B; Vuong, C; Winter, RW; Xie, L; Zeng, Q; Zhang, J; Zhang, P | 1 |
| Collignon, PJ | 1 |
| Back, DJ; Bangchang, KN; Karbwang, J | 1 |
| Back, DJ; Bunnag, D; Karbwang, J; Na Bangchang, K; Thanavibul, A | 1 |
| Trigg, PI | 1 |
| Sugioka, Y; Suzuki, M | 1 |
| Back, DJ; Breckenridge, AM; Bunnag, D; Karbwang, J | 1 |
| Sukhumanan, T; Suphakawanich, W; Thithapandha, A | 1 |
| Dutta, GP; Puri, SK | 1 |
| Back, DJ; Riviere, JH | 1 |
| Dixon, KE; Phintuyothin, P; Pitaktong, U | 1 |
| Salako, LA | 1 |
| Ferrante, A; Goh, DH | 1 |
| Prüfer, L; von Sonnenburg, F | 1 |
| Peters, W | 1 |
| Abdel-Rasoul, S; Königk, E; Mirtsch, S; Putfarken, B | 1 |
| Howells, RE; Judge, BM | 1 |
| Sweeney, TR | 1 |
| Hoffman, SL; Johnson, A; Koech, D; Oloo, AJ; Weiss, WR | 1 |
| Wilberschied, L | 1 |
| Kennedy, CA; Lobel, HO; Newton, JA; Oldfield, EC; Schnepf, GA; Wallace, MR | 1 |
| Holfels, E; Mack, D; McAuley, J; McLeod, R; Milhous, WK | 1 |
| Bangchang, KN; Bunnag, D; Harinasuta, T; Karbwang, J; Rooney, W; Thimasarn, K | 1 |
| Davis, TM; Edwards, G; McGrath, CS; Pukrittayakamee, S; Supanaranond, W; Ward, SA; White, NJ | 1 |
| Davis, DR; Hutton, DC; Rieckmann, KH; Simpson, R; Wheatley, PF; Yeo, AE | 1 |
| DeFraites, RF; Kain, KC; Magill, AJ; Smoak, BL; Wellde, BT | 1 |
| Kozarsky, PE; Lobel, HO | 1 |
| Boele van Hensbroek, M; Kager, PA; Wetsteyn, JC; Zijlmans, CW | 1 |
| Schwartz, E; Sidi, Y | 1 |
| Davis, TM | 1 |
| Bray, PG; Mungthin, M; Ridley, RG; Ward, SA | 1 |
| Coyne, PE; Lobel, HO; Rosenthal, PJ | 1 |
| Juckett, G | 1 |
| Botella de Maglia, J; Espacio Casanovas, A | 1 |
| Regev-Yochay, G; Schwartz, E | 1 |
| Auparakkitanon, S; Chavalitshewinkoon-Petmitr, P; Pongvilairat, G; Wilairat, P | 1 |
| Dalvi, SS; Gogtay, NJ; Kshirsagar, NA; Rajgor, D; Wakde, M | 1 |
| Myrvang, B | 1 |
| Bhagwat, AN; Bhatt, R; Godse, C; Joshi, J; Vaidya, AD; Vaidya, RA | 1 |
| Kramer, MH; Lobel, HO | 1 |
| Kain, KC; Keystone, JS; Shanks, GD | 1 |
| Jong, EC; Nothdurft, HD | 1 |
| Coley, AM; Fadden, P; Foley, M; Graves, PR; Hardeman, K; Haystead, TA; Kwiek, JJ; Ray, R | 1 |
| Gal, N; Tamary, H; Zvulunov, A | 1 |
| Nakajima, Y | 1 |
| Peters, W; Robinson, BL; Stewart, LB | 1 |
| Chaikachonpatd, S; Chanthapakajee, K; Chindarat, S; Kaewkaukul, N; Lim, K; Silpasakorn, S; Suputtamongkol, Y; Thamlikitkul, V | 1 |
| Chambers, JA | 1 |
| Amklad, I; Looareesuwan, S; Rojanawatsirivej, C; Vijaykadga, S; Wilairatna, P | 1 |
| Bangchang, KN; Congpuong, K; Rojanawatsirivet, C; Thongphua, S; Thongsri, K; Vijaykadga, S; Wernsdorfer, WH; Wilairatana, P | 1 |
| Baird, JK | 1 |
| Chen, LH; Schlagenhauf, P; Wilson, ME | 1 |
| Clark, SL; Crawford, P; Nichols, W; Reamy, BV | 1 |
| Dubberke, ER; Weil, GJ | 1 |
| Brittenham, GM; Kano, S; Krudsood, S; Li, G; Looareesuwan, S; Pengruksa, C; Phophak, N; Tangpukdee, N; Thanachartwet, V; Wilairatana, P | 1 |
| Allbaugh, R; Battina, S; Das, S; Hua, DH; Jena, S; Lin, D; Shi, A; Takemoto, DJ | 1 |
| Freedman, DO | 1 |
| Barreto Miranda, I; Löscher, T | 1 |
| Croft, AM; Jacquerioz, FA | 2 |
| Alvarez, LG; Blair, S; Ríos, A; Sanín, F; Tobón, A; Vásquez, AM | 1 |
| Biswas, B; Ghosh, A; Mallick, D; Thapa, R | 1 |
| Alvarez, G; Blair, S; Piñeros, JG; Ríos, A; Tobón, A | 1 |
| Bodammer, P; Holtfreter, MC; Kinzelbach, R; Klammt, S; Loebermann, M; Reisinger, EC; Riebold, D; Sombetzki, M | 1 |
| Ashley, E; Aung, PP; Imwong, M; Kyaw, MK; Lee, SJ; Myint, NZ; Naing, AL; Nyo, MY; Oo, AP; Phe, O; Smithuis, F; White, NJ; Win, T | 1 |
| Imre, T; Iványi, R; Jicsinszky, L; Mizsei, R; Németh, K; Simonyi, M; Szemán, J; Szente, L; Tárkányi, G; Varga, E; Visy, J | 1 |
| Park, JM; Sung, YH | 1 |
| Croft, AM | 1 |
| Moreira-Campos, LM; Nogueira, FH; Pianetti, GA; Santos, RL | 1 |
| Bozzo, P; Einarson, A; Irvine, MH | 1 |
| Arango, EM; Carmona-Fonseca, J; Upegui, YA | 1 |
| Garner, P; Gelband, H; Graves, PM | 3 |
| Amnuaysirikul, J; Caridha, D; Gao, X; Grogl, M; Hickman, M; Ishida, H; Li, Q; Magill, AJ; O'Neil, MT; Ohrt, C; Ray, P; Weina, PJ; Zhang, P | 1 |
| Baresel, PC; Campo, B; Magill, AJ; Ohrt, C; Rochford, R; Sampath, A; Tekwani, BL; Walker, LA | 1 |
| Choi, AR; Kim, JH; Kim, YK; Yoon, S | 1 |
| Al-Rashadan, M; Amr, ZS; Bani Hani, R; Kanani, K; Shadfan, B | 1 |
| David, K; Møller, CH | 1 |
| Albrecht, L; Angerami, RN; Castiñeiras, CM; Costa, FT; Dos-Santos, JC; Garcia, MT; Lacerda, MV; Levy, CE; Lopes, SC; Moretti, ML | 1 |
| Cabrera, M; Cui, L | 1 |
| Bhardwaj, J; Goyal, M; Prakash, K; Puri, SK; Siddiqui, AJ; Soni, A | 1 |
| Maayan, N; Pace, C; Saunders, R; Sinclair, D; Tickell-Painter, M | 1 |
| Choi, L; Garner, P; Gelband, H; Graves, PM | 1 |
| Churcher, ZR; Johnson, PE; Slavkovic, S | 1 |
| Lardo, S; Liwang, F; Ratih, DM | 1 |
| Bhatia, SN; Grilo Ruivo, MT; Lemos Rocha, LF; Mancio-Silva, L; Marques, S; Mota, MM; Vera, IM | 1 |
| Brett-Major, D; Fraser, J; Hickey, PW; Mitra, I; Riddle, MS; Tribble, DR | 1 |
26 review(s) available for primaquine and mefloquine
| Article | Year |
|---|---|
Using genetic methods to define the targets of compounds with antimalarial activity.
Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum | 2013 |
Approaches to protozoan drug discovery: phenotypic screening.
Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacokinetics of antimalarial drugs: their therapeutic and toxicological implications.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Half-Life; Humans; Kinetics; Male; Mefloquine; Mice; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine; Sulfalene | 1985 |
[Progress in immunodiagnosis and chemotherapy of protozoan infections].
Topics: Amebiasis; Animals; Antibodies; Babesiosis; Chloroquine; Drug Resistance, Microbial; Giardiasis; Humans; Leishmaniasis; Malaria; Mefloquine; Pneumocystis; Pneumonia, Pneumocystis; Primaquine; Protozoan Infections; Pyrimethamine; Quinine; Quinolines; Serologic Tests; Sulfadoxine; Tetracycline; Toxoplasmosis; Trypanosomiasis | 1983 |
New answers through chemotherapy?
Topics: Aminoquinolines; Animals; Antimalarials; Chemical Phenomena; Chemistry; Disease Models, Animal; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Humans; Liver; Malaria; Mefloquine; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Quinine; Quinolines; Research; Sesquiterpenes; Species Specificity; World Health Organization | 1984 |
The present status of malaria chemotherapy: mefloquine, a novel antimalarial.
Topics: Amodiaquine; Animals; Antimalarials; Aotus trivirgatus; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dogs; Drug Therapy, Combination; Erythrocytes; Female; Humans; Lethal Dose 50; Macaca mulatta; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Protein Conformation; Pyrimethamine; Quinolines; Rats; Stereoisomerism; Swine | 1981 |
[The treatment of malaria].
Topics: Adult; Antimalarials; Chloroquine; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Pregnancy; Primaquine | 1997 |
Malaria prevention in travelers.
Topics: Animals; Antimalarials; Bedding and Linens; Chloroquine; Doxycycline; Humans; Malaria; Malaria, Falciparum; Mefloquine; Patient Education as Topic; Plasmodium falciparum; Primaquine; Proguanil; Protective Clothing; Teaching Materials; Travel | 1999 |
[Malaria in Norway--diagnosis, treatment and prevention].
Topics: Antimalarials; Chloroquine; Humans; Insect Bites and Stings; Malaria; Malaria, Falciparum; Mefloquine; Norway; Practice Guidelines as Topic; Primaquine; Travel | 2000 |
Antimalarial chemoprophylaxis in infants and children.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Doxycycline; Humans; Infant; Malaria, Falciparum; Mefloquine; Primaquine | 2001 |
Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens.
Topics: Animals; Antimalarials; Atovaquone; Azithromycin; Chloroquine; Drug Resistance; Health Planning Guidelines; Humans; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Primaquine; Proguanil | 2001 |
Current drugs for antimalarial chemoprophylaxis: a review of efficacy and safety.
Topics: Antimalarials; Atovaquone; Chloroquine; Doxycycline; Humans; Malaria; Mefloquine; Naphthoquinones; Primaquine; Proguanil | 2001 |
[Antiprotozoal drugs].
Topics: Animals; Antiprotozoal Agents; Drug Combinations; Emetine; Humans; Mefloquine; Metronidazole; Phenanthrenes; Primaquine; Protozoan Infections; Pyrimethamine; Quinine; Sulfadoxine; Tinidazole | 2003 |
Military aviators, special operations forces, and causal malaria prophylaxis.
Topics: Aminoquinolines; Antimalarials; Atovaquone; Aviation; Chloroquine; Doxycycline; Drug Combinations; Humans; Malaria; Mefloquine; Military Personnel; Naphthoquinones; Primaquine; Proguanil; United States | 2003 |
Effectiveness of antimalarial drugs.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Life Cycle Stages; Malaria; Mefloquine; Patient Compliance; Plasmodium; Primaquine; Pyrimethamine; Quinine; Secondary Prevention; Sulfadoxine; Treatment Failure | 2005 |
Controversies and misconceptions in malaria chemoprophylaxis for travelers.
Topics: Antimalarials; Consensus; Health Knowledge, Attitudes, Practice; Humans; Internationality; Malaria; Mefloquine; Practice Guidelines as Topic; Primaquine; Travel | 2007 |
Clinical practice. Malaria prevention in short-term travelers.
Topics: Adult; Animals; Antimalarials; Child; DEET; Drug Resistance; Endemic Diseases; Female; Humans; Malaria; Male; Mefloquine; Plasmodium; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Risk Assessment; Travel | 2008 |
Drugs for preventing malaria in travellers.
Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Doxycycline; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Primaquine; Proguanil; Randomized Controlled Trials as Topic; Travel | 2009 |
Malaria: prevention in travellers.
Topics: Antimalarials; Bedding and Linens; Chloroquine; Humans; Malaria; Mefloquine; Primaquine; Travel | 2010 |
Primaquine for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2012 |
Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2014 |
Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2015 |
WITHDRAWN: Drugs for preventing malaria in travellers.
Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Doxycycline; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Primaquine; Proguanil; Randomized Controlled Trials as Topic; Travel | 2015 |
Mefloquine for preventing malaria during travel to endemic areas.
Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Doxycycline; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Primaquine; Proguanil; Randomized Controlled Trials as Topic; Travel-Related Illness | 2017 |
Primaquine or other 8-aminoquinolines for reducing Plasmodium falciparum transmission.
Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Non-Randomized Controlled Trials as Topic; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine; Time Factors | 2018 |
11 trial(s) available for primaquine and mefloquine
| Article | Year |
|---|---|
Pharmacokinetics of mefloquine in the presence of primaquine.
Topics: Adult; Animals; Diarrhea; Drug Interactions; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Primaquine; Surveys and Questionnaires | 1992 |
A clinical trial of mefloquine in the treatment of Plasmodium vivax malaria.
Topics: Adult; Chloroquine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium vivax; Primaquine; Quinolines; Random Allocation | 1985 |
The present status of malaria chemotherapy: mefloquine, a novel antimalarial.
Topics: Amodiaquine; Animals; Antimalarials; Aotus trivirgatus; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dogs; Drug Therapy, Combination; Erythrocytes; Female; Humans; Lethal Dose 50; Macaca mulatta; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Protein Conformation; Pyrimethamine; Quinolines; Rats; Stereoisomerism; Swine | 1981 |
Daily primaquine is effective for prophylaxis against falciparum malaria in Kenya: comparison with mefloquine, doxycycline, and chloroquine plus proguanil.
Topics: Adolescent; Child; Chloroquine; Doxycycline; Drug Administration Schedule; Humans; Kenya; Malaria, Falciparum; Mefloquine; Primaquine; Proguanil | 1995 |
Recent military experience with malaria chemoprophylaxis.
Topics: Antimalarials; Australia; Chloroquine; Dapsone; Doxycycline; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Military Personnel; Primaquine; Pyrimethamine | 1993 |
The efficacy of combined mefloquine-artesunate versus mefloquine-primaquine on subsequent development of Plasmodium falciparum gametocytemia.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Carrier State; Child; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Plasmodium falciparum; Primaquine; Secondary Prevention; Sesquiterpenes | 2003 |
Monitoring the therapeutic efficacy of antimalarials against uncomplicated falciparum malaria in Thailand.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Middle Aged; Primaquine; Sesquiterpenes; Statistics, Nonparametric; Thailand; Treatment Outcome | 2003 |
Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Primaquine; Prospective Studies; Quinolines; Thailand; Treatment Outcome | 2008 |
[Therapeutic efficacy of a regimen of artesunate-mefloquine-primaquine treatment for Plasmodium falciparum malaria and treatment effects on gametocytic development].
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Drug Resistance; Drug Therapy, Combination; Female; Fever; Germ Cells; Humans; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Patient Compliance; Pilot Projects; Plasmodium falciparum; Primaquine; Treatment Outcome; Young Adult | 2009 |
Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Myanmar; Plasmodium falciparum; Primaquine; Treatment Outcome; Young Adult | 2010 |
Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Colombia; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Germ Cells; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Plasmodium falciparum; Primaquine; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult | 2012 |
57 other study(ies) available for primaquine and mefloquine
| Article | Year |
|---|---|
Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?
Topics: Aminoquinolines; Animals; Antimalarials; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Hemin; Hepatocytes; Humans; In Vitro Techniques; Liver; Mice; Microsomes, Liver; Parasite Load; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Tetraoxanes | 2016 |
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Topics: Acridones; Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Hep G2 Cells; Humans; Malaria; Mice; Plasmodium; Species Specificity; Structure-Activity Relationship | 2019 |
Chloroquine-resistant Plasmodium vivax: it may be a common problem.
Topics: Animals; Chloroquine; Drug Resistance; Female; Humans; Malaria, Vivax; Male; Mefloquine; Plasmodium vivax; Primaquine | 1992 |
Mefloquine metabolism by human liver microsomes. Effect of other antimalarial drugs.
Topics: Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Humans; Ketoconazole; Kinetics; Mefloquine; Microsomes, Liver; Primaquine; Quinine | 1992 |
Drug use and design in the nineties.
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine | 1991 |
The chemical basis for the ferriprotoporphyrin IX-chloroquine complex induced lipid peroxidation.
Topics: Animals; Antimalarials; Apoproteins; Benzoates; Benzoic Acid; Catalase; Chloroquine; Hemin; Hydrogen-Ion Concentration; Iron; Kinetics; Lipid Peroxidation; Liposomes; Mefloquine; Oxygen; Primaquine; Quinine; Rats; Spectrum Analysis; Superoxide Dismutase; Transferrin | 1991 |
Recommendations for the prevention of malaria among travelers.
Topics: Adult; Animals; Antimalarials; Breast Feeding; Centers for Disease Control and Prevention, U.S.; Child; Chloroquine; Doxycycline; Drug Resistance; Female; Humans; Malaria; Mefloquine; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Primaquine; Proguanil; Risk Factors; Travel; United States | 1990 |
Pharmacokinetics of mefloquine in combination with sulfadoxine-pyrimethamine and primaquine in male Thai patients with falciparum malaria.
Topics: Adolescent; Adult; Animals; Drug Resistance; Drug Therapy, Combination; Half-Life; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Sulfadoxine | 1990 |
Comparative inhibitory effects of mefloquine and primaquine on hepatic drug-metabolizing enzymes.
Topics: Alcohol Oxidoreductases; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Enzyme Inhibitors; Liver; Male; Mefloquine; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Primaquine; Rats; Rats, Inbred Strains | 1990 |
Delay in emergence of mefloquine resistance in Plasmodium berghei by use of drug combinations.
Topics: Animals; Antimalarials; Dapsone; Drug Resistance; Drug Therapy, Combination; Erythromycin; Malaria; Mefloquine; Mice; Plasmodium berghei; Primaquine; Quinolines | 1989 |
Effect of mefloquine on hepatic drug metabolism in the rat: comparative study with primaquine.
Topics: Aminopyrine; Animals; Antimalarials; Ethinyl Estradiol; In Vitro Techniques; Male; Mefloquine; Microsomes, Liver; Mixed Function Oxygenases; Primaquine; Quinolines; Rats; Rats, Inbred Strains; Tolbutamide | 1985 |
The effect of anti-malarial drugs on human natural killer cells in vitro.
Topics: Antimalarials; Cell Line; Chloroquine; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Leukemia, Myeloid, Acute; Mefloquine; Primaquine; Pyrimethamine; Quinacrine; Quinine; Quinolines | 1984 |
Plasmodium chabaudi-infection of mice: effects of chloroquine and mefloquine. Inhibition of ornithine decarboxylase activity.
Topics: Acridines; Animals; Antimalarials; Carboxy-Lyases; Chloroquine; Enzyme Repression; Erythrocyte Membrane; Malaria; Mefloquine; Mice; Ornithine Decarboxylase Inhibitors; Piperidines; Plasmodium; Primaquine; Quinolines | 1981 |
Sustained-release implants in the chemotherapy of experimental rodent malaria I. A comparison of the effects of some antimalarials in polydimethylsiloxane matrices.
Topics: Animals; Antimalarials; Chloroquine; Dimethylpolysiloxanes; Drug Implants; Malaria; Male; Mefloquine; Mice; Mice, Inbred Strains; Naphthoquinones; Piperidines; Plasmodium berghei; Primaquine; Proguanil; Pyrimethamine; Quinolines; Silicone Elastomers; Sulfadiazine; Triazines | 1981 |
Malaria in Kansas, 1988-1993.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Resistance; Female; Humans; Kansas; Malaria; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Primaquine; Travel | 1994 |
Malaria in US Marines returning from Somalia.
Topics: Cohort Studies; Disease Outbreaks; Doxycycline; Humans; Incidence; Malaria; Mefloquine; Military Personnel; Primaquine; Somalia; Treatment Refusal; United States | 1994 |
In vitro effects of artemisinin ether, cycloguanil hydrochloride (alone and in combination with sulfadiazine), quinine sulfate, mefloquine, primaquine phosphate, trifluoperazine hydrochloride, and verapamil on Toxoplasma gondii.
Topics: Animals; Artemisinins; Female; Mefloquine; Mice; Primaquine; Proguanil; Quinine; Sesquiterpenes; Sulfadiazine; Toxoplasma; Triazines; Trifluoperazine; Uracil; Verapamil | 1994 |
Mefloquine level monitoring in patients with multidrug resistant Plasmodium falciparum on the Thai Myanmar border.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Cambodia; Chromatography, High Pressure Liquid; Drug Combinations; Drug Monitoring; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Primaquine; Pyrimethamine; Sulfadoxine; Thailand; Treatment Outcome | 1993 |
Interactions among primaquine, malaria infection and other antimalarials in Thai subjects.
Topics: Acute Disease; Administration, Oral; Adult; Drug Interactions; Humans; Malaria, Falciparum; Male; Mefloquine; Primaquine; Quinine; Thailand | 1993 |
Plasmodium vivax infections in U.S. Army troops: failure of primaquine to prevent relapse in studies from Somalia.
Topics: Adolescent; Adult; Animals; Antimalarials; Drug Resistance; Humans; Malaria, Vivax; Male; Mefloquine; Military Personnel; Patient Compliance; Plasmodium vivax; Primaquine; Recurrence; Somalia; Surveys and Questionnaires; United States | 1997 |
Update on prevention of malaria for travelers.
Topics: Animals; Antimalarials; Chloroquine; Doxycycline; Drug Resistance; Global Health; Guidelines as Topic; Humans; Malaria; Mefloquine; Plasmodium; Primaquine; Proguanil; Travel | 1997 |
New aspects of malaria imported from Ethiopia.
Topics: Animals; Antimalarials; Chloroquine; Culicidae; Disease Reservoirs; Drug Therapy, Combination; Ethiopia; Humans; Incidence; Insect Vectors; Israel; Malaria, Vivax; Mefloquine; Primaquine; Travel | 1998 |
Adverse effects of antimalarial prophylactic drugs: an important consideration in the risk-benefit equation.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Atovaquone; Azithromycin; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Naphthoquinones; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Risk Assessment | 1998 |
Central role of hemoglobin degradation in mechanisms of action of 4-aminoquinolines, quinoline methanols, and phenanthrene methanols.
Topics: Amodiaquine; Antimalarials; Chloroquine; Hemoglobins; Humans; Leucine; Mefloquine; Phenanthrenes; Primaquine; Protease Inhibitors | 1998 |
Drug overdoses with antimalarial agents: prescribing and dispensing errors.
Topics: Aged; Aged, 80 and over; Antifungal Agents; Antimalarials; Drug Overdose; Female; Humans; Malaria, Vivax; Male; Medication Errors; Mefloquine; Middle Aged; Naphthalenes; Onychomycosis; Primaquine; Terbinafine | 1998 |
[Prevention of malaria].
Topics: Anti-Bacterial Agents; Antimalarials; Chloroquine; Doxycycline; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Proguanil; Risk Assessment; Risk Factors; Time Factors; Travel | 1999 |
Primaquine as prophylaxis for malaria for nonimmune travelers: A comparison with mefloquine and doxycycline.
Topics: Adult; Aged; Animals; Anti-Bacterial Agents; Antimalarials; Doxycycline; Female; Follow-Up Studies; Humans; Hydroxychloroquine; Immunization; Incidence; Israel; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Primaquine; Retrospective Studies; Travel | 1999 |
Gametocytocidal activity of pyronaridine and DNA topoisomerase II inhibitors against multidrug-resistant Plasmodium falciparum in vitro.
Topics: Amsacrine; Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Enzyme Inhibitors; Etoposide; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Naphthyridines; Norfloxacin; Nucleic Acid Synthesis Inhibitors; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Thailand; Topoisomerase II Inhibitors; Triazines | 2000 |
An unusual case of multidrug-resistant Plasmodium vivax malaria in Mumbai (Bombay), India.
Topics: Adolescent; Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Humans; India; Malaria, Vivax; Male; Mefloquine; Plasmodium vivax; Primaquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2000 |
Vivax malaria: also a challenge to biomedical sciences and services.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria, Vivax; Mefloquine; Plasmodium vivax; Primaquine | 1999 |
Discovery of novel targets of quinoline drugs in the human purine binding proteome.
Topics: Adenosine Triphosphate; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Antimalarials; Chloroquine; Chromatography, Agarose; Enzyme Inhibitors; Erythrocytes; Humans; Isoenzymes; Mefloquine; Mice; NAD(P)H Dehydrogenase (Quinone); Plasmodium falciparum; Primaquine; Proteome; Retinal Dehydrogenase; Sepharose | 2002 |
Pancytopenia resulting from hemophagocytosis in malaria.
Topics: Animals; Antimalarials; Child; Diagnosis, Differential; Female; Histiocytosis, Non-Langerhans-Cell; Humans; Malaria; Mefloquine; Pancytopenia; Plasmodium falciparum; Plasmodium vivax; Primaquine | 2002 |
The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines.
Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Resistance; Drug Therapy, Combination; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Mice; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Primaquine; Time Factors | 2003 |
Declining mefloquine sensitivity of Plasmodium falciparum along the Thai-Myanmar border.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Myanmar; Parasitic Sensitivity Tests; Plasmodium falciparum; Primaquine; Regression Analysis; Sesquiterpenes; Thailand; Treatment Outcome | 2004 |
Clinical inquiries. When should travelers begin malaria prophylaxis?
Topics: Antimalarials; Chloroquine; Contraindications; Doxycycline; Humans; Insect Repellents; Insecticides; Internet; Malaria; Mefloquine; Occlusive Dressings; Permethrin; Practice Guidelines as Topic; Primaquine; Time Factors; Travel | 2007 |
A woman from Honduras with a painful forearm and fever.
Topics: Adult; Animals; Antimalarials; Female; Fever; Honduras; Humans; Malaria, Vivax; Mefloquine; Pain; Plasmodium vivax; Primaquine; Radius Fractures; Texas; Treatment Outcome | 2008 |
Protection of retinal cells from ischemia by a novel gap junction inhibitor.
Topics: Animals; Apoptosis; Cell Line; Cobalt; Gap Junctions; Ischemia; Mefloquine; Primaquine; Rats; Retina; Retinal Vessels | 2008 |
[Malaria--current diagnosis and therapy].
Topics: Antimalarials; Blood; Developing Countries; Diagnosis, Differential; Female; Humans; Malaria, Vivax; Mefloquine; Papua New Guinea; Philippines; Primaquine; Retreatment; Travel; Young Adult | 2009 |
Symmetrical peripheral gangrene in childhood falciparum malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Female; Gangrene; Humans; Malaria, Falciparum; Mefloquine; Primaquine | 2010 |
Dynamics of Plasmodium falciparum parasitemia regarding combined treatment regimens for acute uncomplicated malaria, Antioquia, Colombia.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Clinical Protocols; Colombia; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Patient Compliance; Plasmodium falciparum; Primaquine; Treatment Outcome | 2010 |
Schistosoma mansoni: schistosomicidal effect of mefloquine and primaquine in vitro.
Topics: Animals; Antimalarials; Biomphalaria; Cercaria; Larva; Mefloquine; Mice; Primaquine; Schistosoma mansoni; Schistosomicides | 2011 |
Enantiomeric separation of antimalarial drugs by capillary electrophoresis using neutral and negatively charged cyclodextrins.
Topics: Aminoquinolines; Anions; Antimalarials; beta-Cyclodextrins; Chloroquine; Cyclodextrins; Electrophoresis, Capillary; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mefloquine; Primaquine; Stereoisomerism | 2011 |
[A case of malarial hepatitis by Plasmodium vivax].
Topics: Abdomen; Antimalarials; Erythrocytes; Fatigue; Hepatitis; Humans; Malaria, Vivax; Male; Mefloquine; Nausea; Plasmodium vivax; Primaquine; Ultrasonography; Young Adult | 2010 |
Quality of essential drugs in tropical countries: evaluation of antimalarial drugs in the Brazilian Health System.
Topics: Antimalarials; Brazil; Chloroquine; Chromatography, High Pressure Liquid; Drug Storage; Drugs, Essential; Humans; Mefloquine; Primaquine; Quality Control; Quinine | 2011 |
Prophylactic use of antimalarials during pregnancy.
Topics: Antimalarials; Atovaquone; Chemoprevention; Chloroquine; Doxycycline; Drug Combinations; Female; Humans; Hydroxychloroquine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Proguanil; Travel | 2011 |
An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines.
Topics: Acute Disease; Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genotype; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Haptoglobins; Hemolytic Agents; Male; Mefloquine; Mice; Phenotype; Primaquine; Reticulocyte Count | 2013 |
Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.
Topics: Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Combined Modality Therapy; Dapsone; Dose-Response Relationship, Drug; Doxycycline; Drug Evaluation, Preclinical; Erythrocyte Count; Erythrocyte Transfusion; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Mefloquine; Mice; Mice, Inbred NOD; Mice, SCID; Primaquine; Pyrimethamine; Reproducibility of Results; Sensitivity and Specificity; Transplantation, Heterologous | 2013 |
Co-treatment with the anti-malarial drugs mefloquine and primaquine highly sensitizes drug-resistant cancer cells by increasing P-gp inhibition.
Topics: Antimalarials; Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chloroquine; Doxycycline; Drug Resistance, Neoplasm; Humans; Mefloquine; Primaquine; Verapamil; Vinblastine | 2013 |
A retrospective study on imported malaria in Jordan. 1. Malaria among Jordanian UN peacekeeping forces.
Topics: Adult; Antimalarials; Cote d'Ivoire; Doxycycline; Drug Therapy, Combination; Endemic Diseases; Eritrea; Humans; Jordan; Malaria; Male; Mefloquine; Middle Aged; Military Personnel; Occupational Exposure; Post-Exposure Prophylaxis; Premedication; Primaquine; Recurrence; Sierra Leone; Timor-Leste | 2014 |
Imported malaria is stable from Africa but declining from Asia.
Topics: Adolescent; Adult; Africa; Aged; Antimalarials; Asia; Atovaquone; Chemoprevention; Child; Child, Preschool; Chloroquine; Delayed Diagnosis; Denmark; Drug Combinations; Female; Humans; Incidence; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Primaquine; Proguanil; Recurrence; Risk Factors; Severity of Illness Index; Travel; Young Adult | 2014 |
Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anemia; Antimalarials; Artemether; Artemisinins; Brazil; Chloroquine; Comorbidity; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Parasitemia; Primaquine; Recurrence; Retrospective Studies; Tertiary Care Centers; Thrombocytopenia; Travel; Young Adult | 2014 |
In Vitro Activities of Primaquine-Schizonticide Combinations on Asexual Blood Stages and Gametocytes of Plasmodium falciparum.
Topics: Antimalarials; Benzothiazoles; Chloroquine; Diamines; Drug Combinations; Drug Interactions; Erythrocytes; Ethanolamines; Flow Cytometry; Fluorenes; Humans; Lumefantrine; Mefloquine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Primaquine; Quinolines; Sporozoites; Trophozoites | 2015 |
Repetitive live sporozoites inoculation under arteether chemoprophylaxis confers protection against subsequent sporozoite challenge in rodent malaria model.
Topics: Animals; Antimalarials; Artemisinins; Chemoprevention; Chloroquine; Female; Immunization; Malaria; Mefloquine; Mice; Parasite Load; Plasmodium yoelii; Primaquine; Sporozoites; Vaccination | 2016 |
Nanomolar binding affinity of quinine-based antimalarial compounds by the cocaine-binding aptamer.
Topics: Amodiaquine; Antimalarials; Aptamers, Nucleotide; Binding Sites; Chloroquine; Cocaine; Ligands; Mefloquine; Primaquine; Quinine; Thermodynamics | 2018 |
Plasmodium ovale Infection After One Year Mefloquine Prophylaxis in A Young Indonesian Soldier: A Case Report.
Topics: Antimalarials; Artemisinins; Chemoprevention; Congo; Drug Therapy, Combination; Humans; Indonesia; Malaria; Male; Mefloquine; Military Personnel; Plasmodium ovale; Primaquine; Young Adult | 2019 |
Targeting liver stage malaria with metformin.
Topics: Animals; Antimalarials; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Repositioning; Drug Therapy, Combination; Hepatocytes; Humans; Inhibitory Concentration 50; Liver; Malaria; Male; Mefloquine; Metformin; Mice; Parasite Load; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Primaquine; Primary Cell Culture | 2019 |
Deployment and Travel Medicine Knowledge, Attitudes, Practices, and Outcomes Study (KAPOS): Malaria Chemoprophylaxis Prescription Patterns in the Military Health System.
Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Chemoprevention; Chloroquine; Doxycycline; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Military Medicine; Military Personnel; Practice Patterns, Physicians'; Primaquine; Proguanil; United States; Young Adult | 2020 |