primaquine has been researched along with bulaquine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 11 (52.38) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Espadinha, M; Gonçalves, LM; Gut, J; Machado, M; Moreira, R; Prudêncio, M; Ribeiro, CJ; Rosenthal, PJ; Santos, MM | 1 |
| Dutta, GP; Pandey, VC; Puri, SK; Sahni, SK; Srivastava, P; Tripathi, LM | 1 |
| Dutta, GP; Puri, SK | 2 |
| Dutta, GP; Pandey, VC; Puri, SK; Saxena, N | 1 |
| Bhaduri, AP; Dutta, GP; Puri, SK; Seth, M | 1 |
| Dutta, GP; Pandey, VC; Puri, SK; Sethi, N; Srivastava, R | 1 |
| Dutta, GP; Pandey, VC; Puri, SK; Srivastava, P | 1 |
| Grover, PK; Gupta, RC; Paliwal, JK | 1 |
| Gupta, RC; Paliwal, JK | 1 |
| Jain, GK; Pandey, VC; Puri, SK; Singh, S; Srivastava, P | 1 |
| Adak, T; Sharma, VP; Valecha, N | 1 |
| Gupta, RC; Lal, J; Mehrotra, N | 1 |
| Gupta, RC; Lal, J; Madhusudanan, KP; Nitin, M; Rajanikanth, M | 1 |
| Dwivedi, AK; Saxena, D; Singh, S | 1 |
| Aigal, U; Chogle, AR; Dalvi, SS; Gogtay, NJ; Kamtekar, KD; Kshirsagar, NA | 1 |
| Aigal, U; Chogle, AR; Dalvi, SS; Gogtay, NJ; Kamtekar, KD; Kshirsagar, NA; Mehta, SS | 1 |
| Brittenham, GM; Chalermrut, K; Krudsood, S; Looareesuwan, S; Luplertlop, N; Muangnoicharoen, S; Srivilairit, S; Tangpukdee, N; Thanachartwet, V; Wilairatana, P | 1 |
| Gupta, RC; Lal, J; Madhusudanan, KP; Mehrotra, N; Puri, SK | 1 |
| Noel, S; Rath, SK; Shankar, R; Sharma, S | 1 |
| Choi, L; Garner, P; Gelband, H; Graves, PM | 1 |
1 review(s) available for primaquine and bulaquine
| Article | Year |
|---|---|
Primaquine or other 8-aminoquinolines for reducing Plasmodium falciparum transmission.
Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Non-Randomized Controlled Trials as Topic; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine; Time Factors | 2018 |
4 trial(s) available for primaquine and bulaquine
| Article | Year |
|---|---|
Plasmodium vivax polymorphism in a clinical drug trial.
Topics: Administration, Oral; Animals; Antimalarials; Double-Blind Method; Drug Administration Schedule; Drug Resistance; Follow-Up Studies; Genetic Variation; Humans; Malaria, Vivax; Phenotype; Plasmodium vivax; Polymorphism, Genetic; Primaquine; Secondary Prevention | 2001 |
Preliminary report of the evaluation of the gametocytocidal action of bulaquine, in adult patients with acute, Plasmodium falciparum malaria.
Topics: Acute Disease; Adult; Animals; Antimalarials; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitemia; Primaquine; Quinine | 2004 |
A randomized, parallel study of the safety and efficacy of 45 mg primaquine versus 75 mg bulaquine as gametocytocidal agents in adults with blood schizonticide-responsive uncomplicated falciparum malaria [ISCRTN50134587].
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Doxycycline; Drug Administration Schedule; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Primaquine; Quinine; Time Factors; Treatment Outcome | 2006 |
Safety and tolerability of elubaquine (bulaquine, CDRI 80/53) for treatment of Plasmidium vivax malaria in Thailand.
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Female; Humans; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Primaquine; Prospective Studies; Thailand | 2006 |
16 other study(ies) available for primaquine and bulaquine
| Article | Year |
|---|---|
Novel squaramides with in vitro liver stage antiplasmodial activity.
Topics: Antiprotozoal Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Liver; Malaria; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Structure-Activity Relationship | 2016 |
Kinetic and substrate binding characterization of hepatic mixed function oxidase system in monkeys with primaquine and (N1-3-acetyl-4-5-dihydro-2-furanyl)-N4-(methoxy-8-quinolinyl) 1,4-peptane-diamine.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Binding, Competitive; Enzyme Activation; Haplorhini; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Primaquine; Substrate Specificity | 1992 |
Causal prophylactic activity of a new 8-aminoquinoline derivative against Plasmodium cynomolgi B in rhesus monkeys.
Topics: Animals; Antimalarials; Macaca mulatta; Malaria; Primaquine | 1990 |
Effect of a new 8-aminoquinoline antimalarial compound on hepatic microsomal mixed function oxidase system of mice.
Topics: Aminoquinolines; Animals; Antimalarials; Mice; Microsomes, Liver; Mixed Function Oxygenases; Primaquine | 1989 |
Radical curative activity of a new 8-aminoquinoline derivative (CDRI 80/53) against Plasmodium cynomolgi B in monkeys.
Topics: Aminoquinolines; Animals; Antimalarials; Drug Evaluation, Preclinical; Macaca mulatta; Malaria; Molecular Structure; Primaquine | 1989 |
Methemoglobin toxicity and hematological studies on malaria anti-relapse compound CDRI 80/53 in dogs.
Topics: Aminoquinolines; Animals; Antimalarials; Appetite; Body Weight; Dogs; Female; Male; Methemoglobinemia; Primaquine | 1989 |
Effect of the antimalarial agents primaquine and (N'-3-acetyl-4-5-dihydro-2-furanyl)-N4-(6-methoxy-8-quinolinyl)1,4-pent ane-diamine on oxidative stress and antioxidant defences in mice.
Topics: Animals; Catalase; Lipid Peroxides; Liver; Mice; Primaquine; Superoxide Dismutase; Superoxides | 1993 |
Simultaneous determination of a new antimalarial agent, CDRI compound 80/53, and its metabolite primaquine in serum by high-performance liquid chromatography.
Topics: Antimalarials; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Primaquine | 1993 |
A rapid and sensitive high performance liquid chromatographic assay of the new antimalarial compound 80/53 in serum with a novel sample clean-up method and its pharmacokinetics in rabbits.
Topics: Animals; Antimalarials; Chromatography, High Pressure Liquid; Haplorhini; Humans; Primaquine; Rabbits; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1998 |
A simple and rapid evaluation of methemoglobin toxicity of 8-aminoquinolines and related compounds.
Topics: Administration, Cutaneous; Administration, Oral; Aminoquinolines; Animals; Antimalarials; Artemisinins; Cell-Free System; Chloroquine; Cytochrome-B(5) Reductase; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Macaca mulatta; Methemoglobin; Methemoglobinemia; Muridae; Oxyhemoglobins; Primaquine; Rats; Sesquiterpenes | 2000 |
Analysis and pharmacokinetics of bulaquine and its major metabolite primaquine in rabbits using an LC-UV method--a pilot study.
Topics: Administration, Oral; Animals; Antimalarials; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Stability; Food-Drug Interactions; Half-Life; Indicators and Reagents; Male; Primaquine; Rabbits; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2003 |
Liquid chromatography-tandem mass spectrometric assay with a novel method of quantitation for the simultaneous determination of bulaquine and its metabolite, primaquine, in monkey plasma.
Topics: Animals; Antimalarials; Haplorhini; Primaquine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2003 |
HPLC and HPTLC assays for the antimalarial agents chloroquine, primaquine and bulaquine.
Topics: Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Primaquine | 2003 |
Plasmodium cynomolgi: gametocytocidal activity of the anti-malarial compound CDRI 80/53 (elubaquine) in rhesus monkeys.
Topics: Animals; Anopheles; Antimalarials; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Insect Vectors; Macaca mulatta; Malaria; Male; Plasmodium cynomolgi; Primaquine | 2005 |
In Vitro and In Vivo pharmacokinetic studies of bulaquine (analogue of primaquine), a novel antirelapse antimalarial, in rat, rabbit and monkey--highlighting species similarities and differences.
Topics: Administration, Oral; Animals; Antimalarials; Area Under Curve; Biological Availability; Chromatography, Liquid; Erythrocytes; Half-Life; Injections, Intravenous; Macaca mulatta; Male; Metabolic Clearance Rate; Molecular Structure; Primaquine; Protein Binding; Rabbits; Rats; Rats, Sprague-Dawley; Solutions; Species Specificity; Tandem Mass Spectrometry | 2007 |
Identification of differentially expressed genes after acute exposure to bulaquine (CDRI 80/53) in mice liver.
Topics: Alanine Transaminase; Animals; Antimalarials; Aspartate Aminotransferases; Dose-Response Relationship, Drug; Gene Expression Profiling; Liver; Male; Mice; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Primaquine; RNA, Messenger | 2008 |