Page last updated: 2024-08-16

primaquine and 5-hydroxyprimaquine

primaquine has been researched along with 5-hydroxyprimaquine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Allahyari, R; Fraser, IM; Strother, A; Verbiscar, AJ1
Ni, YC; Wang, MJ; Xu, YQ1
Augusto, O; Vasquez-Vivar, J2
Barton, PF; Fletcher, KA; Kelly, JA1
Bowman, ZS; Jollow, DJ; McMillan, DC; Oatis, JE; Whelan, JL1
Bowman, ZS; Jollow, DJ; McMillan, DC; Morrow, JD1
Arsanok, M; Bennett, J; Buathong, N; Chandara, S; Dysoley, L; Fukuda, M; Heng, TK; Hom, S; Ittiverakul, M; Kodchakorn, C; Kuntawunginn, W; Lanteri, C; Ly, S; Nareth, K; Nou, S; Oung, P; Pybus, B; Reichard, G; Rekol, H; Saunders, D; Sea, D; Smith, P; Sok, S; Spring, M; Ta-Aksorn, W; Vanachayangkul, P; Vesely, B; Waters, NC; Wojnarski, M1

Other Studies

8 other study(ies) available for primaquine and 5-hydroxyprimaquine

ArticleYear
Synthesis of certain hydroxy analogues of the antimalarial drug primaquine and their in vitro methemoglobin-producing and glutathione-depleting activity in human erythrocytes.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Erythrocytes; Glutathione; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methemoglobin; Primaquine

1984
Rat liver microsomal and mitochondrial metabolism of primaquine in vitro.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Microsomes, Liver; Mitochondria, Liver; Primaquine; Rats

1992
ESR detection of free radical intermediates during autoxidation of 5-hydroxyprimaquine.
    Free radical research communications, 1990, Volume: 9, Issue:3-6

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Oxidation-Reduction; Oxygen Consumption; Primaquine; Spin Labels

1990
Studies on the mechanisms of oxidation in the erythrocyte by metabolites of primaquine.
    Biochemical pharmacology, 1988, Jul-01, Volume: 37, Issue:13

    Topics: Aminoquinolines; Ditiocarb; Edetic Acid; Erythrocytes; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Methemoglobin; Oxidation-Reduction; Oxyhemoglobins; Primaquine

1988
Oxidative activity of primaquine metabolites on rat erythrocytes in vitro and in vivo.
    Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2

    Topics: Animals; Biotransformation; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocytes; Hydrogen Peroxide; Imines; Male; Methemoglobin; Oxidation-Reduction; Primaquine; Quinones; Rats; Rats, Wistar

1994
Primaquine-induced hemolytic anemia: susceptibility of normal versus glutathione-depleted rat erythrocytes to 5-hydroxyprimaquine.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:1

    Topics: Anemia, Hemolytic; Animals; Drug Stability; Electrochemistry; Erythrocytes; Glutathione; Hemolysis; Male; Methemoglobin; Primaquine; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

2004
Primaquine-induced hemolytic anemia: role of membrane lipid peroxidation and cytoskeletal protein alterations in the hemotoxicity of 5-hydroxyprimaquine.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:2

    Topics: Anemia, Hemolytic; Animals; Antimalarials; Calcium; Cell Membrane; Cytoskeletal Proteins; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Erythrocyte Membrane; Erythrocytes; Ethylmaleimide; In Vitro Techniques; Ionophores; Lipid Bilayers; Lipid Peroxidation; Male; Phosphatidylserines; Primaquine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spleen

2005
Measurements of 5,6-Orthoquinone, a Surrogate for the Presumed Active Primaquine Metabolite 5-Hydroxyprimaquine, in the Urine of Cambodian Adults.
    Antimicrobial agents and chemotherapy, 2022, 03-15, Volume: 66, Issue:3

    Topics: Adult; Antimalarials; Asian People; Cytochrome P-450 CYP2D6; Humans; Malaria, Vivax; Plasmodium vivax; Primaquine

2022