Compounds > pregnenolone sulfate
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pregnenolone sulfate and picrotoxin

pregnenolone sulfate has been researched along with picrotoxin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mienville, JM; Vicini, S1
Majewska, MD; Schwartz, RD1
Richardson, CM; Wakerley, JB1
Covey, DF; Mennerick, S; Shen, W; Zorumski, CF; Zorumski, EC1
Bidziński, A; Członkowska, AI; Krzaścik, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J1
Bidziński, A; Członkowska, AI; Krzaścik, P; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Szyndler, J; Taracha, E; Turzyńska, D; Walkowiak, J; Wisłowska, A; Zienowicz, M1
Bamber, BA; Jorgensen, EM; Marik, PS; Piper, D; Rutar, T; Wardell, B1
Caley, A; Gielen, MC; Harvey, RJ; Smart, TG; Wilkins, ME1

Other Studies

8 other study(ies) available for pregnenolone sulfate and picrotoxin

ArticleYear
Pregnenolone sulfate antagonizes GABAA receptor-mediated currents via a reduction of channel opening frequency.
    Brain research, 1989, Jun-05, Volume: 489, Issue:1

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorides; Ion Channels; Membrane Potentials; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnenolone; Rats; Receptors, GABA-A

1989
Pregnenolone-sulfate: an endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain?
    Brain research, 1987, Feb-24, Volume: 404, Issue:1-2

    Topics: Adrenal Glands; Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Male; Muscimol; Picrotoxin; Pregnenolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical

1987
The neurosteroid pregnenolone sulphate enhances NMDA-induced phasic firing of vasopressin neurones in the rat supraoptic nucleus.
    Neuroscience letters, 1997, Apr-25, Volume: 226, Issue:2

    Topics: Animals; Dehydroepiandrosterone Sulfate; Drug Synergism; Evoked Potentials; Female; Hypothalamus; In Vitro Techniques; N-Methylaspartate; Neurons; Picrotoxin; Pregnenolone; Rats; Rats, Wistar; Supraoptic Nucleus; Time Factors; Vasopressins

1997
Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors.
    Neuropharmacology, 1999, Volume: 38, Issue:2

    Topics: Animals; Chloride Channels; Dehydroepiandrosterone Sulfate; Female; gamma-Aminobutyric Acid; Macromolecular Substances; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Picrotoxin; Pregnenolone; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis

1999
The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:2

    Topics: Animals; Bicuculline; Central Nervous System Depressants; Convulsants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Picrotoxin; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Reflex; Seizures; Sleep; Steroids

2000
Pregnenolone sulfate potentiates the effects of NMDA on hippocampal alanine and dopamine.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:4

    Topics: Alanine; Amino Acids; Animals; Bicuculline; Convulsants; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Male; Mice; Microinjections; N-Methylaspartate; Picrotoxin; Pregnenolone; Seizures

2004
Residues in the first transmembrane domain of the Caenorhabditis elegans GABA(A) receptor confer sensitivity to the neurosteroid pregnenolone sulfate.
    British journal of pharmacology, 2006, Volume: 148, Issue:2

    Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans Proteins; Dimerization; Dose-Response Relationship, Drug; Female; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutant Chimeric Proteins; Mutation; Oocytes; Picrotoxin; Pregnenolone; Rats; Receptors, GABA-A; Sequence Homology, Amino Acid; Xenopus laevis

2006
Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.
    The Journal of physiology, 2016, 07-01, Volume: 594, Issue:13

    Topics: Desoxycorticosterone; Glycine; HEK293 Cells; Humans; Hyperekplexia; Models, Molecular; Mutation, Missense; Picrotoxin; Pregnenolone; Receptors, Glycine; Zinc

2016