pregnenolone sulfate has been researched along with gamma-aminobutyric acid in 26 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 11 (42.31) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Barnard, EA; Darlison, MG; Harvey, RJ; Shingai, R; Zaman, SH | 1 |
| Miledi, R; Polenzani, L; Woodward, RM | 1 |
| Majewska, MD; Vaupel, DB | 1 |
| Majewska, MD; Mienville, JM; Vicini, S | 1 |
| Hauser, CA; Holsboer, F; Rupprecht, R; Wetzel, CH | 1 |
| Acosta-Burruel, M; Goodnough, DB; Hawkinson, JE; Kimbrough, CL; Wood, PL | 1 |
| Gillies, GE; Murray, HE | 1 |
| Feltz, P; Poisbeau, P; Schlichter, R | 1 |
| Kasparov, S; Kravitz, EA; Rahamimoff, R; Teschemacher, A | 1 |
| Chapell, R; Leidenheimer, NJ | 1 |
| Horiguchi, J; Kagaya, A; Takebayashi, M; Uchitomi, Y; Yamawaki, S; Yokota, N | 1 |
| Covey, DF; Mennerick, S; Shen, W; Zorumski, CF; Zorumski, EC | 1 |
| Covey, DF; Mennerick, S; Shen, W; Zorumski, CF | 1 |
| Akk, G; Bracamontes, J; Steinbach, JH | 1 |
| Jhangri, GS; Le Mellédo, JM; Semeniuk, T | 1 |
| Simmonds, MA; Sooksawate, T | 1 |
| Bertram, EH; Kapur, J; Mtchedlishvili, Z | 1 |
| Benz, A; Covey, DF; Eisenman, LN; Fields, C; Fu, T; He, Y; Mathews, J; Mennerick, S; Steinbach, JH; Wang, M; Zeng, CM; Zorumski, CF; Zorumski, E | 1 |
| Homanics, GE; Huguenard, JR; Huntsman, MM; Mihalek, RM; Porcello, DM | 1 |
| Kapur, J; Mtchedlishvili, Z | 1 |
| Bäckström, T; Johansson, IM; Lindblad, C; Rahman, M; Wang, MD | 1 |
| Akk, G; Bracamontes, J; Covey, DF; Li, P; Reichert, DE; Steinbach, JH | 1 |
| Bäckström, T; Haage, D; Lundgren, P; Strömberg, J; Taube, M; Wang, M | 1 |
| Beaumont, M; Maccaferri, G | 1 |
| Bright, DP; Liebowitz, S; Seljeset, S; Smart, TG | 1 |
| Ernst, M; Frølund, B; Krall, J; Mortensen, M; Shehata, MA; Smart, TG; Xu, Y | 1 |
26 other study(ies) available for pregnenolone sulfate and gamma-aminobutyric acid
| Article | Year |
|---|---|
Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid.
Topics: Animals; Base Sequence; DNA; gamma-Aminobutyric Acid; Humans; Macromolecular Substances; Molecular Sequence Data; Oocytes; Polymerase Chain Reaction; Pregnanolone; Pregnenolone; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Xenopus laevis | 1992 |
Effects of steroids on gamma-aminobutyric acid receptors expressed in Xenopus oocytes by poly(A)+ RNA from mammalian brain and retina.
Topics: Animals; Bicuculline; Brain; Cattle; Cerebral Cortex; gamma-Aminobutyric Acid; Membrane Potentials; Oocytes; Poly A; Pregnenolone; Rats; Receptors, GABA-A; Retina; RNA; Steroids; Transfection; Xenopus | 1992 |
Steroid control of uterine motility via gamma-aminobutyric acidA receptors in the rabbit: a novel mechanism?
Topics: Animals; Female; gamma-Aminobutyric Acid; Pregnanolone; Pregnenolone; Progesterone; Progestins; Rabbits; Receptors, GABA-A; Stimulation, Chemical; Uterine Contraction | 1991 |
Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Pentobarbital; Pregnenolone; Rats; Steroids | 1988 |
Allopregnanolone acts as an inhibitory modulator on alpha1- and alpha6-containing GABA-A receptors.
Topics: Animals; Anti-Anxiety Agents; Cell Line; Cell Membrane; Chloride Channels; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypothalamus; Kinetics; Membrane Potentials; Molecular Sequence Data; Muscimol; Neurons; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection | 1996 |
Steroid inhibition of [3H]SR 95531 binding to the GABAA recognition site.
Topics: Allosteric Regulation; Androstanes; Animals; Azasteroids; Cell Membrane; Cerebral Cortex; Desoxycorticosterone; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pregnanolone; Pregnenolone; Protein Binding; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids | 1996 |
Differential effects of neuroactive steroids on somatostatin and dopamine secretion from primary hypothalamic cell cultures.
Topics: Animals; Bicuculline; Cells, Cultured; Dehydroepiandrosterone Sulfate; Dopamine; Drug Synergism; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Pregnanolone; Pregnenolone; Rats; Somatostatin | 1997 |
Modulation of GABAA receptor-mediated IPSCs by neuroactive steroids in a rat hypothalamo-hypophyseal coculture model.
Topics: Animals; Animals, Newborn; Cells, Cultured; Electrophysiology; Female; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Membrane Potentials; Pentobarbital; Pregnancy; Pregnanes; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A | 1997 |
Presynaptic action of the neurosteroid pregnenolone sulfate on inhibitory transmitter release in cultured hippocampal neurons.
Topics: Animals; Cells, Cultured; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Neurons; Patch-Clamp Techniques; Pregnenolone; Presynaptic Terminals; Rats | 1997 |
Effects of PKC activation and receptor desensitization on neurosteroid modulation of GABA(A) receptors.
Topics: Animals; Anti-Anxiety Agents; Chloride Channels; Desoxycorticosterone; Enzyme Activation; Female; gamma-Aminobutyric Acid; Humans; Kinetics; Oocytes; Phorbol Esters; Pregnenolone; Protein Kinase C; Receptors, GABA-A; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Xenopus laevis | 1997 |
Differential regulation by pregnenolone sulfate of intracellular Ca2+ increase by amino acids in primary cultured rat cortical neurons.
Topics: Acetylcholine; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; gamma-Aminobutyric Acid; N-Methylaspartate; Neurons; Potassium; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A | 1998 |
Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors.
Topics: Animals; Chloride Channels; Dehydroepiandrosterone Sulfate; Female; gamma-Aminobutyric Acid; Macromolecular Substances; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Picrotoxin; Pregnenolone; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 1999 |
Pregnenolone sulfate modulates inhibitory synaptic transmission by enhancing GABA(A) receptor desensitization.
Topics: Animals; beta-Alanine; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pregnenolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Synaptic Transmission; Taurine | 2000 |
Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunit.
Topics: Binding Sites; Cell Line; Estranes; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Ligands; Membrane Potentials; Mutagenesis; Nitriles; Patch-Clamp Techniques; Pentobarbital; Piperidines; Pregnenolone; Receptors, GABA-A; Transfection | 2001 |
Neuroactive steroid levels in patients with generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Dehydroepiandrosterone; Female; gamma-Aminobutyric Acid; Humans; Male; Pregnanolone; Pregnenolone; Receptors, GABA-A | 2001 |
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Diazepam; Electric Conductivity; Epilepsy, Temporal Lobe; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Pregnanolone; Pregnenolone; Pyridines; Rats; Receptors, GABA-A; Zinc; Zolpidem | 2001 |
3beta -hydroxypregnane steroids are pregnenolone sulfate-like GABA(A) receptor antagonists.
Topics: Amino Acid Substitution; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Flumazenil; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hydroxysteroids; Lorazepam; Oocytes; Patch-Clamp Techniques; Pregnanes; Pregnenolone; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship; Synapses; Xenopus laevis | 2002 |
Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.
Topics: Anesthetics; Animals; Desoxycorticosterone; Evoked Potentials; Female; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neural Pathways; Pregnenolone; Receptors, GABA-A; Synapses; Thalamus | 2003 |
A presynaptic action of the neurosteroid pregnenolone sulfate on GABAergic synaptic transmission.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; GTP-Binding Proteins; Hippocampus; Pertussis Toxin; Pregnenolone; Rats; Receptors, sigma; Sigma-1 Receptor; Synaptic Transmission | 2003 |
Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte.
Topics: Androstane-3,17-diol; Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Pregnanediol; Pregnanes; Pregnenolone; Protein Subunits; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; RNA, Messenger; Steroids; Xenopus laevis; Zolpidem | 2006 |
Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids.
Topics: Amino Acid Substitution; Animals; Cell Line; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutant Proteins; Mutation; Piperidines; Pregnanetriol; Pregnanolone; Pregnenolone; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, GABA-A; Serine; Steroids; Tryptophan | 2008 |
The effect of the neuroactive steroid 5beta-pregnane-3beta, 20(R)-diol on the time course of GABA evoked currents is different to that of pregnenolone sulphate.
Topics: Animals; Electrophysiology; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Neurons; Patch-Clamp Techniques; Pregnanediol; Pregnenolone; Preoptic Area; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Is connexin36 critical for GABAergic hypersynchronization in the hippocampus?
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbenoxolone; Connexins; Epilepsy; gamma-Aminobutyric Acid; Gap Junction delta-2 Protein; Gap Junctions; Hippocampus; In Vitro Techniques; Interneurons; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Patch-Clamp Techniques; Pregnenolone; Receptors, GABA-A | 2011 |
Pre- and postsynaptic modulation of hippocampal inhibitory synaptic transmission by pregnenolone sulphate.
Topics: Animals; gamma-Aminobutyric Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Neurosteroids; Pregnenolone; Rats; Receptors, GABA-A; Synaptic Transmission; TRPM Cation Channels | 2023 |
Pregnenolone sulfate analogues differentially modulate GABA
Topics: gamma-Aminobutyric Acid; Pregnenolone; Receptors, GABA-A | 2023 |