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pregnenolone sulfate and dehydroepiandrosterone

pregnenolone sulfate has been researched along with dehydroepiandrosterone in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199017 (31.48)18.7374
1990's11 (20.37)18.2507
2000's19 (35.19)29.6817
2010's7 (12.96)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baulieu, EE; Corpéchot, C; Egestad, B; Morfin, R; Sjövall, J; Young, J1
Flood, JF; Morley, JE; Roberts, E1
Hirato, K; Hondo, T; Saito, H; Suzuki, T; Yanaihara, T1
Chibbar, R; Mitchell, BF1
Abdallah, MA; Baulieu, EE; Jo, DH; Robel, P; Young, J1
Godfrey, BM; Petrucco, OM; Seamark, RF; Stone, BA1
de la Torre, B; Hedman, M; Norén, S; Sjöberg, B1
Walsh, SW1
Kakumoto, Y; Kamiya, T; Kiryu, Y; Maruyama, T; Nakamoto, H; Ookawa, H; Suzuki, O; Yasui, T; Yasumura, K; Yokomori, H1
Berthezene, F; Boizel, R; Bost, M; Cathiard, AM; de Peretti, E; Halimi, S; Saez, JM1
Axelson, M; Baulieu, EE; Corpéchot, C; Robel, P; Sjövall, J; Synguelakis, M; Talha, S; Vihko, R1
Deppe, WM; Joubert, SM; Marivate, M; Norman, RJ1
Capella-Pavlovsky, M; Castanier, M; Chartier, M; Daffos, F; Forestier, F; Nahoul, K; Scholler, R1
Hemsell, PG; Korte, K; Mason, JI1
de Peretti, E; Mappus, E1
Carr, BR; Mason, JI; Parker, CR; Simpson, ER1
Carette, B; Poulain, P1
Lukkarinen, O; Ruokonen, A; Vihko, R1
Gromadzińska, E; Lachowicz, L; Rebas, E; Zylińska, L1
Baulieu, EE; Mahé, V; Monnet, FP; Robel, P1
Santen, RJ; Santner, SJ1
Bergeron, R; de Montigny, C; Debonnel, G2
Bohr, I; Gniot-Szulzycka, J1
Baulieu, EE; Corpéchot, C; Eychenne, B; Haug, M; Perché, F; Robel, P; Young, J1
Jhangri, GS; Le Mellédo, JM; Semeniuk, T1
Amino, N; Fukata, S; Izumi, Y; Kobayashi, Y; Kuma, K; Tada, H; Tagawa, N; Takano, T1
Lachowicz, A; Pawlikowski, M; Rebas, E1
Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A1
Guillemain, I; Maurice, T; Phan, VL; Urani, A1
Le Moal, M; Mayo, W; Vallée, M1
Fujiwara, M; Furusawa, H; Higashi, S; Maeda, Y; Matsu, T; Nakahara, H; Nanba, K; Setoguchi, T; Tanaka, E; Watanabe, R1
Heydari, B; Le Mellédo, JM1
Ortega, E; Torres, JM1
CALVIN, HI; LIEBERMAN, S1
KILLINGER, DW; SOLOMON, S1
SCHEDEWIE, H; TAMM, J; VOIGT, KD; VOLKWEIN, U1
Kamei, H; Nabeshima, T; Noda, Y; Yamada, K1
Bicíková, M; Budesínský, M; Cerný, I; Hampl, R; Hill, M; Pouzar, V1
Bicíková, M; Hampl, R; Havlíková, H; Hill, M; Jirák, R; Rípová, D; Tallová, J1
Baulieu, EE; Cambourg, A; Eychenne, B; Griffiths, W; Liere, P; Liu, S; Pianos, A; Schumacher, M; Sjövall, J1
Hou, YN; Yan, CZ1
Cerný, I; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Popov, P; Pouzar, V; Stárka, L; Vrbíková, J1
Hou, YN; Wang, N; Wu, HH1
Cerny, I; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Pouzar, V; Stárka, L; Vrbíková, J1
Hamann, M; Richter, A; Richter, F1
Basta-Kaim, A; Budziszewska, B; Jagla, G; Jantas, D; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Nowak, W; Regulska, M1
Elfverson, M; Johansson, T; Nyberg, F; Zhou, Q1
Chang, F; Chen, L; Sokabe, M; Xie, G; Xu, B; Yang, R1
Horishita, T; Okura, D; Sata, T; Sudo, Y; Ueno, S; Uezono, Y; Yanagihara, N1
Lucchi, C; Pinetti, D; Puia, G; Ravazzini, F; Rustichelli, C1
Bingsohn, L; Dezhkam, Y; Failing, K; Galuska, CE; Hartmann, MF; Hoffmann, B; Sánchez-Guijo, A; Schuler, G; Wudy, SA1
Bernhardt, R; Gerber, A; Hartmann, MF; Neunzig, J; Oji, V; Sánchez-Guijo, A; Schuppe, HC; Traupe, H; Wudy, SA1
Hartmann, MF; Sánchez-Guijo, A; Tiosano, D; Wang, R; Wudy, SA1

Reviews

4 review(s) available for pregnenolone sulfate and dehydroepiandrosterone

ArticleYear
[2 surgically treated cases of adrenocortical carcinoma producing steroid hormones without endocrinological symptoms--case report and a review of cases in the Japanese literature].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:1

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adult; Carcinoma; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Etiocholanolone; Humans; Male; Pregnenolone

1988
[Steroid modulation of GABA(A) receptors].
    Postepy higieny i medycyny doswiadczalnej, 1995, Volume: 49, Issue:3

    Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; GABA Modulators; Lipid Metabolism; Pregnenolone; Proteins; Receptors, GABA-A; Steroids

1995
Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging.
    Brain research. Brain research reviews, 2001, Volume: 37, Issue:1-3

    Topics: Aging; Animals; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hippocampus; Humans; Learning; Memory; Pregnenolone; Rats; Reproducibility of Results

2001
[Effects of sigma receptor ligands on psychiatric disorders].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2003, Volume: 23, Issue:5

    Topics: Animals; Dehydroepiandrosterone; Disease Models, Animal; Humans; Learning Disabilities; Ligands; Memory Disorders; Mental Disorders; Pregnenolone; Progesterone; Receptors, sigma; Sigma-1 Receptor; Stress, Psychological; Substance-Related Disorders

2003

Trials

1 trial(s) available for pregnenolone sulfate and dehydroepiandrosterone

ArticleYear
Secretion of steroid sulfates from human testis and their response to a single intramuscular injection of 5000 IU hCG.
    Journal of steroid biochemistry, 1981, Volume: 14, Issue:12

    Topics: Adult; Aged; Androstenediol; Androstenediols; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Kinetics; Male; Middle Aged; Pregnenolone; Testis; Testosterone; Veins

1981

Other Studies

49 other study(ies) available for pregnenolone sulfate and dehydroepiandrosterone

ArticleYear
Neurosteroids: pregnenolone in human sciatic nerves.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-01, Volume: 89, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Esters; Female; Humans; Male; Mass Spectrometry; Middle Aged; Pregnenolone; Radioimmunoassay; Sciatic Nerve

1992
Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-01, Volume: 89, Issue:5

    Topics: Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Male; Memory; Mice; Pregnenolone; Steroids; Testosterone

1992
Steroid sulfatase activities in human leukocytes: biochemical and clinical aspects.
    Endocrinologia japonica, 1991, Volume: 38, Issue:6

    Topics: Arylsulfatases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrone; Female; Humans; Ichthyosis Vulgaris; Ichthyosis, X-Linked; Leukocytes; Male; Placenta; Pregnenolone; Steryl-Sulfatase; Tritium

1991
Steroid sulfohydrolase in human chorion and decidua: studies using pregnenolone sulfate and dehydroepiandrosterone sulfate as substrate.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:6

    Topics: Arylsulfatases; Chorion; Culture Techniques; Decidua; Dehydroepiandrosterone; Estrogens; Estrone; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; Labor, Obstetric; Microsomes; Pregnancy; Pregnenolone; Progesterone; Steryl-Sulfatase; Sulfatases; Temperature

1990
Pregnenolone, dehydroepiandrosterone, and their sulfate and fatty acid esters in the rat brain.
    Steroids, 1989, Volume: 54, Issue:3

    Topics: Animals; Brain Chemistry; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Esters; Estrus; Fatty Acids; Female; Male; Orchiectomy; Pregnenolone; Radioimmunoassay; Rats; Rats, Inbred Strains

1989
Concentrations of steroid hormones, and of prolactin, in washings of the human uterus during the menstrual cycle.
    Journal of reproduction and fertility, 1986, Volume: 78, Issue:1

    Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Gonadal Steroid Hormones; Humans; Menstrual Cycle; Pregnenolone; Prolactin; Proteins; Uterus

1986
Blood and tissue steroid levels and their interrelationship in men with pathological conditions of the reproductive organs.
    International journal of andrology, 1986, Volume: 9, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arteries; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Epididymis; Genital Diseases, Male; Humans; Male; Middle Aged; Pregnenolone; Steroids; Testis; Testosterone; Vas Deferens; Veins

1986
Progesterone and estradiol production by normal and preeclamptic placentas.
    Obstetrics and gynecology, 1988, Volume: 71, Issue:2

    Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Humans; In Vitro Techniques; Placenta; Pre-Eclampsia; Pregnancy; Pregnenolone; Progesterone

1988
Pattern of plasma levels of cortisol, dehydroepiandrosterone and pregnenolone sulphate in normal subjects and in patients with homozygous familial hypercholesterolaemia during ACTH infusion.
    Clinical endocrinology, 1986, Volume: 25, Issue:4

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Hyperlipoproteinemia Type II; Male; Pregnenolone

1986
Pregnenolone and its sulfate ester in the rat brain.
    Brain research, 1983, Jun-27, Volume: 270, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Dehydroepiandrosterone; Kinetics; Male; Pregnenolone; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium

1983
Umbilical artery concentrations of androstenedione increased in early labour in the leading twin fetus.
    British journal of obstetrics and gynaecology, 1984, Volume: 91, Issue:8

    Topics: Androstenedione; Cesarean Section; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fetal Blood; Humans; Labor Stage, First; Labor Stage, Second; Labor, Obstetric; Pregnancy; Pregnenolone; Progesterone; Twins

1984
[Fetal hormonology by direct sampling of fetal blood during the 2d trimester of pregnancy. Study of fetal and maternal 5-ene steroid sulfates].
    Pathologie-biologie, 1984, Volume: 32, Issue:8

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Blood Specimen Collection; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fetal Blood; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Prenatal Diagnosis

1984
Steroidogenesis in dispersed cells of human fetal adrenal.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:5

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Cyanoketone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Pituitary Hormones; Pregnenolone; Steroid 17-alpha-Hydroxylase; Tetrahydronaphthalenes

1983
Pattern of plasma pregnenolone sulfate levels in humans from birth to adulthood.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aging; Child; Child, Preschool; Chorionic Gonadotropin; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Fetal Blood; Humans; Infant; Infant, Newborn; Male; Metyrapone; Middle Aged; Pregnenolone

1983
Effect of prostaglandins on steroid secretion by human fetal adrenal tissue.
    Steroids, 1983, Volume: 41, Issue:5

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Estradiol; Female; Fetus; Humans; Hydrocortisone; In Vitro Techniques; Pregnancy; Pregnenolone; Prostaglandins E; Prostaglandins F; Radioimmunoassay

1983
Excitatory effect of dehydroepiandrosterone, its sulphate ester and pregnenolone sulphate, applied by iontophoresis and pressure, on single neurones in the septo-preoptic area of the guinea pig.
    Neuroscience letters, 1984, Mar-23, Volume: 45, Issue:2

    Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Guinea Pigs; Membrane Potentials; Neurons; Pregnenolone; Preoptic Area; Septum Pellucidum; Synaptic Transmission

1984
Neuroactive steroids modulate in vivo the Mg2+/Ca(2+)-ATPase activity in rat cortical and cerebellar synaptosomal membranes.
    Biochemical and biophysical research communications, 1995, Jul-06, Volume: 212, Issue:1

    Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calmodulin; Cell Membrane; Cerebellum; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Pregnenolone; Rats; Rats, Wistar; Reference Values; Synaptosomes

1995
Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Apr-25, Volume: 92, Issue:9

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Guanidines; Haloperidol; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ovariectomy; Pertussis Toxin; Piperazines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stereotaxic Techniques; Virulence Factors, Bordetella

1995
Inhibition of estrone sulfatase and 17 beta-hydroxysteroid dehydrogenase by antiestrogens.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:5

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding, Competitive; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Polyunsaturated Alkamides; Pregnenolone; Rats; Rats, Sprague-Dawley; Sulfatases; Tamoxifen

1993
Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Feb-01, Volume: 16, Issue:3

    Topics: Animals; Anisoles; Dehydroepiandrosterone; Drug Synergism; Female; Guanidines; Haloperidol; Hippocampus; Iontophoresis; Ligands; Male; N-Methylaspartate; Pertussis Toxin; Pregnenolone; Progesterone; Propylamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spiperone; Virulence Factors, Bordetella

1996
Neurosteroids in the mouse brain: behavioral and pharmacological effects of a 3 beta-hydroxysteroid dehydrogenase inhibitor.
    Steroids, 1996, Volume: 61, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Brain; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Humans; Mice; Pregnanolone; Pregnenolone; Progesterone; Sexual Behavior, Animal

1996
Potentiation by dehydroepiandrosterone of the neuronal response to N-methyl-D-aspartate in the CA3 region of the rat dorsal hippocampus: an effect mediated via sigma receptors.
    The Journal of endocrinology, 1996, Volume: 150 Suppl

    Topics: Acetylcholine; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Synergism; Female; Hippocampus; Male; N-Methylaspartate; Ovariectomy; Pregnenolone; Progesterone; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, sigma; Stimulation, Chemical; Testosterone

1996
Neuroactive steroid levels in patients with generalized anxiety disorder.
    The Journal of neuropsychiatry and clinical neurosciences, 2001,Summer, Volume: 13, Issue:3

    Topics: Adult; Anxiety Disorders; Dehydroepiandrosterone; Female; gamma-Aminobutyric Acid; Humans; Male; Pregnanolone; Pregnenolone; Receptors, GABA-A

2001
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
    Endocrine journal, 2001, Volume: 48, Issue:3

    Topics: Adult; Androstenediol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Pregnenolone; Sex Characteristics; Sex Hormone-Binding Globulin; Thyroxine

2001
Pregnenolone sulfate modulates angiotensin II-induced inositol 1,4,5-trisphosphate changes in the anterior pituitary of female rat.
    Biochemical and biophysical research communications, 2001, Sep-28, Volume: 287, Issue:3

    Topics: Adjuvants, Immunologic; Angiotensin II; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Estradiol; Female; Inositol 1,4,5-Trisphosphate; Ovary; Pituitary Gland; Pregnenolone; Progesterone; Rats

2001
Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine.
    Clinical chemistry and laboratory medicine, 2001, Volume: 39, Issue:8

    Topics: Adjuvants, Immunologic; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Homocysteine; Humans; Hypothyroidism; Male; Microsomes; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Thyrotropin; Thyroxine; Time Factors; Triiodothyronine

2001
Differential involvement of the sigma(1) (sigma(1)) receptor in the anti-amnesic effect of neuroactive steroids, as demonstrated using an in vivo antisense strategy in the mouse.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Binding Sites; Blotting, Western; Brain; Cerebral Cortex; Dehydroepiandrosterone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Learning Disabilities; Male; Maze Learning; Memory; Mice; Morpholines; Oligonucleotides, Antisense; Phenazocine; Pregnenolone; Receptors, sigma; Sigma-1 Receptor

2001
Accumulation of 4- and 5-ene steroid sulfates in human breast cyst fluids.
    The Journal of steroid biochemistry and molecular biology, 2002, Volume: 81, Issue:3

    Topics: Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Exudates and Transudates; Female; Fibrocystic Breast Disease; Humans; Middle Aged; Pregnenolone

2002
Low pregnenolone sulphate plasma concentrations in patients with generalized social phobia.
    Psychological medicine, 2002, Volume: 32, Issue:5

    Topics: Adult; Arousal; Dehydroepiandrosterone; Humans; Male; Middle Aged; Phobic Disorders; Pilot Projects; Pregnanolone; Pregnenolone; Reference Values

2002
DHEA, PREG and their sulphate derivatives on plasma and brain after CRH and ACTH administration.
    Neurochemical research, 2003, Volume: 28, Issue:8

    Topics: Adrenocorticotropic Hormone; Animals; Blood; Brain; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Male; Pregnenolone; Rats; Rats, Wistar

2003
EVIDENCE THAT STEROID SULFATES SERVE AS BIOSYNTHETIC INTERMEDIATES. II. IN VITRO CONVERSION OF PREGNENOLONE-3H SULFATE-35S TO 17ALPHA-HYDROXYPREGNENOLONE-3H SULFATE-35S.
    Biochemistry, 1964, Volume: 3

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Cushing Syndrome; Dehydroepiandrosterone; Humans; In Vitro Techniques; Infrared Rays; Metabolism; Pregnanediol; Pregnenolone; Sulfates; Sulfur Isotopes; Tritium; Urine

1964
SYNTHESIS OF PREGNENOLONE SULFATE, DEHYDROISOANDROSTERONE SULFATE, 17-ALPHA-HYDROXYPREGNENOLONE SULFATE AND DELTA-5-PREGNENETRIOL SULFATE BY THE NORMAL HUMAN ADRENAL GLAND.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Crystallization; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Metabolism; Pregnanediol; Pregnanetriol; Pregnenes; Pregnenolone; Sulfates; Tritium

1965
METABOLISM OF PREGNENOLONE-3-SULPHATE IN THE PERFUSED DOG LIVER.
    Acta endocrinologica, 1965, Volume: 49

    Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Chromatography; Dehydroepiandrosterone; Dogs; Liver; Perfusion; Pregnenolone; Progesterone; Research; Sulfates; Testosterone

1965
Synthesis of [19- 2H3]-analogs of dehydroepiandrosterone and pregnenolone and their sulfates.
    Steroids, 2004, Volume: 69, Issue:3

    Topics: Androstanes; Combinatorial Chemistry Techniques; Dehydroepiandrosterone; Deuterium; Molecular Structure; Pregnanolone; Pregnenolone

2004
Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia.
    Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:5

    Topics: 17-alpha-Hydroxypregnenolone; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dementia, Vascular; Dipeptides; Female; Glutathione; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Pregnenolone; Radioimmunoassay; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric; Sulfhydryl Compounds

2004
Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain.
    Journal of lipid research, 2004, Volume: 45, Issue:12

    Topics: Animals; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Gas Chromatography-Mass Spectrometry; Male; Pregnenolone; Rats; Rats, Sprague-Dawley

2004
Effects of morphine dependence and withdrawal on levels of neurosteroids in rat brain.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:10

    Topics: Animals; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Male; Morphine Dependence; Pregnenolone; Progesterone; Random Allocation; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

2004
Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction.
    Steroids, 2005, Volume: 70, Issue:8

    Topics: Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Progesterone; Radioimmunoassay; Stereoisomerism; Steroids; Time Factors

2005
[Effects of morphine dependence on the levels of neurosteroids in rat brain].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:11

    Topics: Amygdala; Animals; Brain; Conditioning, Operant; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hypothalamus; Male; Morphine Dependence; Nucleus Accumbens; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley

2005
Serum profiles of free and conjugated neuroactive pregnanolone isomers in nonpregnant women of fertile age.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:8

    Topics: Adult; Aging; Dehydroepiandrosterone; Estradiol; Female; Follicular Phase; Gas Chromatography-Mass Spectrometry; Humans; Isomerism; Luteal Phase; Pregnanolone; Pregnenolone; Progesterone; Receptors, GABA-A

2006
Acute effects of neurosteroids in a rodent model of primary paroxysmal dystonia.
    Hormones and behavior, 2007, Volume: 52, Issue:2

    Topics: Animals; Animals, Genetically Modified; Cricetinae; Dehydroepiandrosterone; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Mesocricetus; Pregnanolone; Pregnenolone

2007
Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells.
    Journal of neuroscience research, 2008, May-01, Volume: 86, Issue:6

    Topics: Apoptosis; Brain; Cell Line, Tumor; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroblastoma; Neurons; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Pregnanolone; Pregnenolone; Staurosporine; Steroids

2008
Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration.
    Biochemical and biophysical research communications, 2010, Oct-29, Volume: 401, Issue:4

    Topics: Allosteric Regulation; Animals; Brain; Dehydroepiandrosterone; Male; Morphine; Neurotransmitter Agents; Opioid-Related Disorders; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2010
Neurosteroid PREGS protects neurite growth and survival of newborn neurons in the hippocampal dentate gyrus of APPswe/PS1dE9 mice.
    Current Alzheimer research, 2012, Volume: 9, Issue:3

    Topics: Alzheimer Disease; Animals; Animals, Newborn; Dehydroepiandrosterone; Dentate Gyrus; Disease Models, Animal; Humans; Male; Mice; Mice, Transgenic; Neural Stem Cells; Neurites; Neurogenesis; Pregnenolone

2012
Inhibition by pregnenolone sulphate, a metabolite of the neurosteroid pregnenolone, of voltage-gated sodium channels expressed in Xenopus oocytes.
    Journal of pharmacological sciences, 2012, Volume: 120, Issue:1

    Topics: Animals; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; NAV1.2 Voltage-Gated Sodium Channel; Oocytes; Pregnenolone; Sodium Channel Blockers; Xenopus laevis

2012
Simultaneous determination of pregnenolone sulphate, dehydroepiandrosterone and allopregnanolone in rat brain areas by liquid chromatography-electrospray tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jul-01, Volume: 930

    Topics: Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Hippocampus; Male; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2013
Free and sulfated steroids secretion in postpubertal boars (Sus scrofa domestica).
    Reproduction (Cambridge, England), 2014, Volume: 148, Issue:3

    Topics: Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Estrone; Male; Pregnenolone; Sus scrofa; Swine; Testis; Testosterone

2014
Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: Evidence from steroid sulfatase deficiency.
    Molecular and cellular endocrinology, 2016, 12-05, Volume: 437

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Child; Child, Preschool; Dehydroepiandrosterone; Estradiol Dehydrogenases; Homeostasis; Humans; Ichthyosis, X-Linked; Middle Aged; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroids; Steryl-Sulfatase; Sulfates; Young Adult

2016
Characterizing the steroidal milieu in amniotic fluid of mid-gestation: A LC-MS/MS study.
    The Journal of steroid biochemistry and molecular biology, 2019, Volume: 185

    Topics: 17-alpha-Hydroxypregnenolone; Amniotic Fluid; Androsterone; Chromatography, Liquid; Dehydroepiandrosterone; Epitestosterone; Estriol; Estrone; Female; Gestational Age; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Steroids; Tandem Mass Spectrometry

2019