pregnenolone carbonitrile has been researched along with warfarin in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Fasco, MJ; Kaminsky, LS; Piper, LJ | 1 |
| Farkas, R; Feuer, G; Kardish, R | 1 |
| Baker, MT; Chiang, CK; Vasquez, MT | 1 |
| Gerstner, E; Heubel, F; Reuter, T | 1 |
| Mathis, JM; Prough, RA; Simpson, ER | 1 |
| Balfour, C; Dunbar, D; Halpert, J; Kaminsky, LS; Miller, NE; Morgan, ET | 1 |
| Dannan, GA; Guengerich, FP; Kaminsky, LS | 1 |
| Porter, WR; Trager, WF; Wheeler, C | 1 |
| Etzrodt, J; Glöckner, R; Lupp, A; Müller, D | 1 |
10 other study(ies) available for pregnenolone carbonitrile and warfarin
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Cumene hydroperoxide-supported microsomal hydroxylations of warfarin--a probe of cytochrome P-450 multiplicity and specificity.
Topics: Animals; Benzene Derivatives; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Peroxides; Phenobarbital; Pregnenolone Carbonitrile; Rats; Stereoisomerism; Warfarin | 1979 |
Differential action of progesterones on hepatic microsomal activities in the rat.
Topics: Aminopyrine N-Demethylase; Animals; Coumarins; Female; Hydroxyprogesterones; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Phospholipids; Phosphoric Monoester Hydrolases; Pregnanediol; Pregnanolone; Pregnenolone Carbonitrile; Progesterone; Rats | 1977 |
Evidence for the stability and cytochrome P450 specificity of the phenobarbital-induced reductive halothane-cytochrome P450 complex formed in rat hepatic microsomes.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Halothane; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Warfarin | 1991 |
Differences between induction effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene and phenobarbitone.
Topics: Animals; Cytochrome P-450 Enzyme System; Diazepam; Enzyme Induction; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Pyridines; Rifampin; Warfarin | 1989 |
Synergistic induction of monooxygenase activity by glucocorticoids and polycyclic aromatic hydrocarbons in human fetal hepatocytes in primary monolayer culture.
Topics: Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzo(a)pyrene; Cells, Cultured; Coumarins; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Female; Fetus; Glucocorticoids; Humans; Hydrocortisone; Hydroxylation; Kinetics; Liver; Oxygenases; Polycyclic Compounds; Pregnancy; Pregnenolone Carbonitrile; Receptors, Glucocorticoid | 1986 |
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chloramphenicol; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Testosterone; Warfarin | 1985 |
Composition of cytochrome P-450 isozymes from hepatic microsomes of C57BL/6 and DBA/2 mice assessed by warfarin metabolism, immunoinhibition, and immunoelectrophoresis with anti-(rat cytochrome P-450).
Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Catalysis; Cytochrome P-450 Enzyme System; Enzyme Induction; Immunochemistry; Immunoelectrophoresis; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Stereoisomerism; Warfarin | 1984 |
Changes in the metabolic profiles of R- and S-warfarin and R- and S-phenprocoumon as a probe to categorize the effect of inducing agents on microsomal hydroxylases.
Topics: 4-Hydroxycoumarins; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenprocoumon; Polychlorinated Dibenzodioxins; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Stereoisomerism; Warfarin | 1981 |
Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.
Topics: Aging; Animals; Anti-Inflammatory Agents; beta-Naphthoflavone; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enzyme Induction; Enzyme Inhibitors; Hydroxylation; Liver; Male; Mixed Function Oxygenases; Organ Culture Techniques; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Testosterone; Time Factors | 2008 |