pregnenolone carbonitrile has been researched along with thyroxine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Selye, H; Taché, J; Taché, Y | 1 |
| Bastomsky, CH; Japundzić, IP; Japundzić, MM | 1 |
| Du Ruisseau, P; Mécs, I; Selye, H; Taché, J; Taché, Y | 1 |
| Davidson, MD; Fujimoto, JM | 1 |
| Mécs, I; Selye, H; Szabo, S | 1 |
| Kourounakis, P; Selye, H; Szabo, S | 1 |
| Garg, BD; Kovacs, K; Szabo, S; Tuchweber, B | 1 |
| Hashmi, R; Hood, A; Klaassen, CD | 1 |
| Hood, A; Klaassen, CD | 1 |
| Klaassen, CD; Vansell, NR | 2 |
| Chen, C; Klaassen, CD; Staudinger, JL | 1 |
| Habeebu, SM; Klaassen, CD; Muppidi, JR; Vansell, NR | 1 |
| Klaassen, CD; Richardson, TA | 1 |
| Fujiwara, R; Hirashima, R; Itoh, T; Kobayashi, Y; Michimae, H; Sasaki, A; Takemoto, H; Tukey, RH | 1 |
15 other study(ies) available for pregnenolone carbonitrile and thyroxine
| Article | Year |
|---|---|
Inhibition of the effects of alfathesin and other steroid anesthetics by catatoxic steroids in rats.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Female; Ketosteroids; Phenobarbital; Phenytoin; Prednisolone; Pregnanediones; Pregnanes; Pregnenes; Pregnenolone Carbonitrile; Rats; Spironolactone; Steroids; Thyroxine; Time Factors | 1975 |
Ehanced biliary thyroxine excretion in rats treated with pregnenolone-16alpha-carbonitrile.
Topics: Animals; Bile; Female; Liver; Organ Size; Pregnenolone Carbonitrile; Rats; Stimulation, Chemical; Thyroid Gland; Thyrotropin; Thyroxine | 1976 |
Regulation of resistance to various toxicants by PCN (pregnenolone-16alpha-carbonitrile) and thyroxine.
Topics: Animals; Dose-Response Relationship, Drug; Drug Antagonism; Drug Resistance; Female; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Sympathetic Nervous System; Thyroxine; Toxicology | 1976 |
Increased permeability of the rat biliary tree by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) treatment and protection by hepatoactive agents.
Topics: Animals; Biliary Tract; Body Weight; Chlordecone; Dioxins; Food Deprivation; Liver; Male; Mannitol; Methimazole; Permeability; Polychlorinated Dibenzodioxins; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Sucrose; Thyroxine | 1987 |
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate.
Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hyperkinesis; Ketosteroids; Methylphenidate; Norpregnanes; Paralysis; Phenobarbital; Phenytoin; Prednisolone; Pregnenolone Carbonitrile; Progesterone; Propionates; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Thyroxine | 1972 |
Effect of pharmacologic conditioning on sulfadiazine toxicity and concentrations in plasma.
Topics: Adrenocorticotropic Hormone; Androstenols; Animals; Depression, Chemical; Desoxycorticosterone; Estradiol; Female; Ketosteroids; Kidney; Organ Size; Phenobarbital; Prednisolone; Pregnanediones; Pregnenolone Carbonitrile; Propionates; Rats; Spironolactone; Stimulation, Chemical; Sulfadiazine; Thyroxine; Triamcinolone | 1974 |
Ultrastructural changes induced by pregnenolone-16 alpha-carbonitrile in the hepatocytes of thyro-parathyroidectomized and L-thyroxine-treated rats.
Topics: Animals; Body Weight; Endoplasmic Reticulum; Female; Liver; Microscopy, Electron; Organ Size; Paralysis; Parathyroid Glands; Pregnenolone Carbonitrile; Rats; Thyroid Gland; Thyroidectomy; Thyroxine; Zoxazolamine | 1973 |
Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy.
Topics: Animals; Cell Count; Cell Division; Chlorodiphenyl (54% Chlorine); Enzyme Activation; Hyperplasia; Hypertrophy; Male; Methylcholanthrene; Organ Size; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1999 |
Differential effects of microsomal enzyme inducers on in vitro thyroxine (T(4)) and triiodothyronine (T(3)) glucuronidation.
Topics: Animals; Chlorodiphenyl (54% Chlorine); Detergents; Enzyme Induction; Glucuronides; Glucuronosyltransferase; In Vitro Techniques; Iodine Radioisotopes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroxine; Triiodothyronine | 2000 |
Increased biliary excretion of thyroxine by microsomal enzyme inducers.
Topics: Animals; Antithyroid Agents; Bile; Carcinogens; Chlorodiphenyl (54% Chlorine); Glucuronides; Male; Methylcholanthrene; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyrotropin; Thyroxine | 2001 |
Increase in rat liver UDP-glucuronosyltransferase mRNA by microsomal enzyme inducers that enhance thyroid hormone glucuronidation.
Topics: Animals; Blotting, Northern; Chlorodiphenyl (54% Chlorine); Electrophoresis, Agar Gel; Enzyme Induction; Glucuronosyltransferase; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity; Thyroid Hormones; Thyroxine; Transcription, Genetic; Triiodothyronine | 2002 |
Nuclear receptor, pregname X receptor, is required for induction of UDP-glucuronosyltranferases in mouse liver by pregnenolone-16 alpha-carbonitrile.
Topics: Administration, Oral; Animals; Bilirubin; Chloramphenicol; Enzyme Induction; Food; Glucuronosyltransferase; Male; Mice; Mice, Mutant Strains; Microsomes, Liver; Naphthols; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Thyroxine; Time Factors; Triiodothyronine; Up-Regulation | 2003 |
Promotion of thyroid tumors in rats by pregnenolone-16alpha-carbonitrile (PCN) and polychlorinated biphenyl (PCB).
Topics: Adenoma; Animals; Antithyroid Agents; Body Weight; Carcinoma; Chlorodiphenyl (54% Chlorine); Eating; Environmental Pollutants; Glucuronides; Hyperplasia; Male; Organ Size; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyroid Neoplasms; Thyrotropin; Thyroxine; Triiodothyronine | 2004 |
Disruption of thyroid hormone homeostasis in Ugt1a-deficient Gunn rats by microsomal enzyme inducers is not due to enhanced thyroxine glucuronidation.
Topics: Animals; Cell Proliferation; Chlorodiphenyl (54% Chlorine); Glucuronosyltransferase; Liver; Male; Methylcholanthrene; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Rats, Gunn; Rats, Wistar; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2010 |
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity.
Topics: Animals; Animals, Newborn; Brain; Carbamazepine; Cell Movement; Enzyme Induction; Female; Gene Expression Regulation, Developmental; Genes, Developmental; Glucuronosyltransferase; Humans; Mice, Inbred C57BL; Mice, Transgenic; Milk, Human; Neurodevelopmental Disorders; Phenytoin; Pregnancy; Pregnenolone Carbonitrile; Prenatal Exposure Delayed Effects; RNA, Messenger; Rotarod Performance Test; Thyroxine | 2016 |