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pregnenolone carbonitrile and proadifen

pregnenolone carbonitrile has been researched along with proadifen in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Drew, RT; Fouts, JR; Lo, RJ; Roth, RP1
Kammerer, RC; Lampe, MA1
Gram, TE; Okine, LK1
Burke, MD; Elcombe, CR; Haaparanta, T; Halpert, J; Mayer, RT; Thompson, S1
Kourounakis, P; Selye, H; Szabo, S; Taché, Y1
Gustafsson, JA; Ingelman-Sundberg, M1
Kourounakis, P; Lykissas, ED1
Davis, M; Powell-Jackson, PR; Smith, HM; Tredger, JM; Williams, R1
Levin, W; Ryan, DE; Thomas, PE; Vlasuk, GP; Walz, FG1
Kupfer, D; Mani, C; Parkinson, A; Pearce, R1

Other Studies

10 other study(ies) available for pregnenolone carbonitrile and proadifen

ArticleYear
Dichloromethane inhalation, carboxyhemoglobin concentrations, and drug metabolizing enzymes in rabbits.
    Toxicology and applied pharmacology, 1975, Volume: 33, Issue:3

    Topics: Animals; Carbon Tetrachloride; Carboxyhemoglobin; Hemoglobins; Hydrocarbons, Chlorinated; Male; Methylcholanthrene; Methylene Chloride; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rabbits

1975
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole

1987
In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Enzyme Induction; Glutathione; Hot Temperature; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; NADP; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Proadifen; Subcellular Fractions

1986
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.
    Biochemical pharmacology, 1985, Sep-15, Volume: 34, Issue:18

    Topics: Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Enzyme Induction; Ethers; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Substrate Specificity

1985
Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in rats.
    Biochemical pharmacology, 1974, Volume: 23, Issue:15

    Topics: Adrenocorticotropic Hormone; Animals; Biotransformation; Brain Chemistry; Dose-Response Relationship, Drug; Drug Antagonism; Female; Metabolic Clearance Rate; Muscles; Paralysis; Pharmaceutical Preparations; Pregnenolone Carbonitrile; Proadifen; Rats; Swine; Time Factors; Toxicology; Zoxazolamine

1974
Regulation and properties of a sex-specific hydroxylase system in female rat liver microsomes active on steroid sulfates. I. General characteristics.
    The Journal of biological chemistry, 1974, Mar-25, Volume: 249, Issue:6

    Topics: Age Factors; Androstanes; Animals; Carbon Monoxide; Carbon Radioisotopes; Castration; Estradiol; Female; Hydroxysteroids; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rats; Sex Factors; Steroid Hydroxylases; Sulfuric Acids; Testosterone

1974
Inhibition by ethionine and beta-diethylaminoethyl diphenylpropylacetate of RNA and protein synthesis in the rat liver, and its reversal by pregnenolone-16 alpha-carbonitrile.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:4

    Topics: Animals; Ethionine; Female; Leucine; Liver; Microsomes, Liver; Orotic Acid; Pregnenolone Carbonitrile; Proadifen; Protein Biosynthesis; Rats; RNA

1980
Effect of rifampicin on the mouse hepatic mixed-function oxidase system.
    Biochemical pharmacology, 1981, May-15, Volume: 30, Issue:10

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rifampin; Sodium Fluoride

1981
Polypeptide patterns of hepatic microsomes from Long-Evans rats treated with different xenobiotics.
    Biochemistry, 1982, Nov-23, Volume: 21, Issue:24

    Topics: Animals; Aroclors; Chlordan; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Isomerism; Male; Methylcholanthrene; Microsomes, Liver; Peptide Biosynthesis; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole; Stilbenes

1982
Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Biotransformation; Chickens; Cricetinae; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Female; Humans; Hydrocortisone; Immunoglobulin G; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Tamoxifen; Troleandomycin

1994