Page last updated: 2024-08-21

pregnenolone carbonitrile and nifedipine

pregnenolone carbonitrile has been researched along with nifedipine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burk, O; Eichelbaum, M; Geick, A1
Jekerle, V; Piquette-Miller, M; Teng, S1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ali, RY; Matheny, CJ; Pollack, GM; Yang, X1

Other Studies

6 other study(ies) available for pregnenolone carbonitrile and nifedipine

ArticleYear
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
    The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors

2001
Induction of ABCC3 (MRP3) by pregnane X receptor activators.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:11

    Topics: Animals; Cell Line, Tumor; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Multidrug Resistance-Associated Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger

2003
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:9

    Topics: Actins; Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Brain; Cytochrome P-450 CYP3A; Dexamethasone; Drug Administration Schedule; Enzyme Induction; Gene Expression Regulation; Hypericum; Intestine, Small; Intubation; Liver; Male; Mice; Mice, Inbred Strains; Nifedipine; Oxidoreductases, N-Demethylating; Plant Extracts; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; Tamoxifen; Time Factors

2004