Compounds > pregnenolone carbonitrile
Page last updated: 2024-08-21

pregnenolone carbonitrile and nadp

pregnenolone carbonitrile has been researched along with nadp in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fasco, MJ; Kaminsky, LS; Piper, LJ1
Castle, MC1
Jaeger, RJ; Moslen, MT; Murphy, SD; Reynolds, ES; Szabo, S1
Kammerer, RC; Lampe, MA1
Gram, TE; Okine, LK1
Hildebrandt, AG; Roots, I; Speck, M1
Einarsson, K; Gustafsson, JA1
Baird, MB1
Costa, AK; Ivanetich, KM1
Floreani, M; Geroni, C; Napoli, E; Quintieri, L; Rosato, A; Sola, F; Zanovello, P1

Other Studies

10 other study(ies) available for pregnenolone carbonitrile and nadp

ArticleYear
Cumene hydroperoxide-supported microsomal hydroxylations of warfarin--a probe of cytochrome P-450 multiplicity and specificity.
    Biochemical pharmacology, 1979, Volume: 28, Issue:1

    Topics: Animals; Benzene Derivatives; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Peroxides; Phenobarbital; Pregnenolone Carbonitrile; Rats; Stereoisomerism; Warfarin

1979
Digitoxin metabolism by rat liver homogenates, subcellular fractions and isolated hepatocytes: stimulation by spironolactone and pregnenolone-16 alpha-carbonitrile.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 211, Issue:1

    Topics: Animals; Biotransformation; Digitoxin; In Vitro Techniques; Liver; Male; Microsomes, Liver; NAD; NADP; Pregnenolone Carbonitrile; Rats; Spironolactone; Subcellular Fractions

1979
Hepatotoxicity of vinyl chloride and 1,1-dichloroethylene. Role of mixed function oxidase system.
    The American journal of pathology, 1975, Volume: 81, Issue:1

    Topics: Animals; Aroclors; Carcinogens; Cell Membrane; Cytochrome P-450 Enzyme System; Dichloroethylenes; Endoplasmic Reticulum; Enzyme Induction; Glutathione; Hexachlorobenzene; Hydrocarbons, Chlorinated; Liver; Liver Neoplasms; Male; Methylcholanthrene; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Vinyl Chloride; Vinyl Compounds

1975
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole

1987
In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Enzyme Induction; Glutathione; Hot Temperature; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; NADP; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Proadifen; Subcellular Fractions

1986
Possible control of hydrogen peroxide production and degradation in microsomes during mixed function oxidation reaction.
    Biochemical and biophysical research communications, 1973, Oct-01, Volume: 54, Issue:3

    Topics: Aminopyrine; Animals; Azides; Catalase; Cytochrome P-450 Enzyme System; Hemeproteins; Hydrogen Peroxide; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Pregnenolone Carbonitrile; Rats; Time Factors

1973
Effect of 16alpha-cyanopregnenolone on the hydroxylation of lithocholic acid by rat liver microsomes.
    Biochemical pharmacology, 1974, Jan-01, Volume: 23, Issue:1

    Topics: Animals; Bile Acids and Salts; Chromatography, Thin Layer; Hydroxylation; Lithocholic Acid; Male; Microsomes, Liver; NADP; Organ Size; Pregnenolone Carbonitrile; Rats; Stimulation, Chemical; Tritium

1974
Microsomal NADPH-dependent lipid peroxidation does not require the presence of intact cytochrome P450.
    Biochemical and biophysical research communications, 1980, Aug-29, Volume: 95, Issue:4

    Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; In Vitro Techniques; Lipid Peroxides; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Pregnenolone Carbonitrile; Rats

1980
Tetrachloroethylene metabolism by the hepatic microsomal cytochrome P-450 system.
    Biochemical pharmacology, 1980, Oct-15, Volume: 29, Issue:20

    Topics: Animals; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Pregnenolone Carbonitrile; Rats; Tetrachloroethylene

1980
In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
    Cancer research, 2000, Jun-15, Volume: 60, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Bone Marrow; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Doxorubicin; Erythromycin; Female; Leukemia, Experimental; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Protein Synthesis Inhibitors; Time Factors; Troleandomycin; Tumor Cells, Cultured

2000