Compounds > pregnenolone carbonitrile
Page last updated: 2024-08-21

pregnenolone carbonitrile and mifepristone

pregnenolone carbonitrile has been researched along with mifepristone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burk, O; Eichelbaum, M; Geick, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Beck, G; Chasserot-Golaz, S; Parcollet, P1
Handschin, C; Hoffmann, K; Meyer, UA; Podvinec, M; Stöckli, J1
Fraga, C; Kumar, N; Narang, VS; Shen, J; Stewart, CF; Throm, S; Waters, CM1

Other Studies

6 other study(ies) available for pregnenolone carbonitrile and mifepristone

ArticleYear
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
    The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors

2001
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Interrelationship between RU38486 and the P450 activities in rat liver.
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: Animals; Biotransformation; Cell Fractionation; Cytochrome P-450 Enzyme System; Dexamethasone; Male; Microsomes, Liver; Mifepristone; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains

1989
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:9

    Topics: Animals; Avian Proteins; beta-Naphthoflavone; Cell Line; Chickens; Clotrimazole; Colforsin; Constitutive Androstane Receptor; Cyclic AMP; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Glutethimide; Growth Inhibitors; Hormone Antagonists; Humans; Metyrapone; Mifepristone; Okadaic Acid; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Signal Transduction; Trans-Activators; Transcription Factors

2001
Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier.
    American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Blotting, Western; Brain; Cells, Cultured; Dexamethasone; Endothelial Cells; Gene Expression; Glucocorticoids; Indenes; Male; Mifepristone; Multidrug Resistance-Associated Proteins; Pregnane X Receptor; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation

2008