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pregnenolone carbonitrile and dimethylnitrosamine

pregnenolone carbonitrile has been researched along with dimethylnitrosamine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Arcos, JC; Argus, MF; Conney, AH; Hoch-Ligeti, C1
Arcos, JC; Argus, MF; Friedman, MA; Greene, EJ; Lai, DY; Myers, SC; Woo, YT1
Grandjean, CJ; Somogyi, A1
Arcos, JC; Argus, MF; Bryant, GM; Buu-Hoi, NP; Valle, RT1
Böhm, N; Kiessling, M; Kleihues, P; Lipinski, R1

Other Studies

6 other study(ies) available for pregnenolone carbonitrile and dimethylnitrosamine

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Differential effects of beta-naphthoflavone and pregnenolone-16alpha-carbonitrile on dimethylnitrosamine-induced hepatocarcinogenesis.
    Journal of the National Cancer Institute, 1978, Volume: 61, Issue:2

    Topics: Animals; Biotransformation; Carcinoma, Hepatocellular; Dimethylnitrosamine; Drug Interactions; Flavonoids; Hemangiosarcoma; Liver Neoplasms; Male; Naphthalenes; Neoplasms, Experimental; Nitrosamines; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Rats

1978
Role of dimethylnitrosamine-demethylase in the metabolic activation of dimethylinitrosamine.
    Chemico-biological interactions, 1979, Volume: 28, Issue:1

    Topics: Biotransformation; Cell Nucleus; Dimethylnitrosamine; DNA; Flavonoids; Microsomes, Liver; Mutagens; Oxidoreductases Acting on CH-NH Group Donors; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile

1979
Effect of pregnenolone-16alpha-caronitrile on the metabolism of dimethylnitrosamine and binding to rat liver macromolecules.
    Biochemical pharmacology, 1976, Sep-15, Volume: 25, Issue:18

    Topics: Animals; Dimethylnitrosamine; DNA; Female; In Vitro Techniques; Liver; Nitrosamines; Pregnenolone Carbonitrile; Protein Binding; Proteins; Rats; RNA; Time Factors

1976
Dimethylnitrosamine-demethylase: molecular size-dependence of repression by polynuclear hydrocarbons. Nonhydrocarbon repressors.
    Journal of toxicology and environmental health, 1976, Volume: 1, Issue:3

    Topics: Animals; Dimethylnitrosamine; Enzyme Repression; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Oxidoreductases, N-Demethylating; Phenobarbital; Polycyclic Compounds; Pregnenolone Carbonitrile; Rats

1976
Effect of pretreatment with pregnenolone-16 alpha-carbonitrile and protein-free diet on the metabolism and carcinogenicity of dimethylnitrosamine.
    Carcinogenesis, 1981, Volume: 2, Issue:8

    Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; Female; Kidney Neoplasms; Methylation; Pregnenolone Carbonitrile; Protein Deficiency; Rats; Rats, Inbred Strains

1981