pregnenolone carbonitrile has been researched along with d-alpha tocopherol in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iconomidis, G; Kourounakis, PN; Rekka, E; Tani, E | 1 |
| Abbott, FS; Huang, HS; Jurima-Romet, M; Tang, W; Whitehouse, LW | 1 |
| Li, YJ; Shaw, HM | 1 |
| Ahn, SH; Cho, JY; Gonzalez, FJ; Idle, JR; Kang, DW; Krausz, KW; Luecke, H; Ma, X | 1 |
| Chen, WH; Shaw, HM | 1 |
5 other study(ies) available for pregnenolone carbonitrile and d-alpha tocopherol
| Article | Year |
|---|---|
Modification of drug metabolic processes by compounds which intervene with the function of cytochrome P-450 as a mono-oxygenase and as an oxidase.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Female; In Vitro Techniques; Linoleic Acids; Lipid Peroxidation; Microsomes, Liver; Mixed Function Oxygenases; Nitrobenzoates; Oxidoreductases; Pharmaceutical Preparations; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Vitamin E | 1989 |
Cytotoxicity of unsaturated metabolites of valproic acid and protection by vitamins C and E in glutathione-depleted rat hepatocytes.
Topics: Analysis of Variance; Animals; Anticonvulsants; Ascorbic Acid; Cells, Cultured; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Glutathione; Homeostasis; L-Lactate Dehydrogenase; Liver; Male; Mass Spectrometry; Methionine; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred F344; Valproic Acid; Vitamin E | 1996 |
Pregnenolone and dexamethasone, modulators of cytochrome P450-3A, not increase but reduce urinary alpha-CEHC excretion in rats.
Topics: alpha-Tocopherol; Animals; Chromans; Cytochrome P-450 CYP3A; Dexamethasone; Ketoconazole; Liver; Male; Pregnenolone Carbonitrile; Propionates; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2007 |
Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation.
Topics: Animals; Chromans; Gene Expression; Humans; Liver; Male; Mass Spectrometry; Metabolomics; Mice; Mice, Knockout; Molecular Structure; Oxidation-Reduction; Pregnane X Receptor; Pregnenolone Carbonitrile; Propionates; Receptors, Steroid; Urine; Vitamin E; Vitamins | 2009 |
Effects of pregnenolone-16alpha-carbonitrile on vitamin E status and protein levels of antioxidant enzymes in male rats fed a vitamin E-supplemented diet.
Topics: alpha-Tocopherol; Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Catalase; Cytochrome P-450 CYP3A; Dietary Supplements; Glutathione Peroxidase; Humans; Lipid Peroxidation; Male; Membrane Proteins; Microsomes, Liver; Organ Size; Pregnenolone Carbonitrile; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2009 |