Compounds > pregnenolone carbonitrile
Page last updated: 2024-08-21

pregnenolone carbonitrile and clotrimazole

pregnenolone carbonitrile has been researched along with clotrimazole in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burk, O; Eichelbaum, M; Geick, A1
Jekerle, V; Piquette-Miller, M; Teng, S1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Chabot, GG; Hanstein, WG; Mahnke, A; Roos, PH1
Cunninghame, ME; Evans, DC; Lake, BG; Price, RJ; Renwick, AB; Surry, D1
Handschin, C; Hoffmann, K; Meyer, UA; Podvinec, M; Stöckli, J1
Chen, K; Coffee, R; Contag, PR; Lu, L; Purchio, AF; West, DB; Wu, J; Zhang, W1

Other Studies

7 other study(ies) available for pregnenolone carbonitrile and clotrimazole

ArticleYear
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
    The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors

2001
Induction of ABCC3 (MRP3) by pregnane X receptor activators.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:11

    Topics: Animals; Cell Line, Tumor; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Multidrug Resistance-Associated Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger

2003
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
In vivo induction of cytochrome P450 CYP3A expression in rat leukocytes using various inducers.
    Biochemical pharmacology, 1996, Jun-14, Volume: 51, Issue:11

    Topics: Animals; Blotting, Western; Clotrimazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Leukocytes; Liver; Male; Microsomes; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rabbits; Rats; Rats, Sprague-Dawley

1996
Comparison of the effects of some CYP3A and other enzyme inducers on replicative DNA synthesis and cytochrome P450 isoforms in rat liver.
    Toxicology, 1998, Nov-02, Volume: 131, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Replication; Enzyme Induction; Female; Isoenzymes; Liver; Miconazole; Mitogens; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Troleandomycin

1998
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:9

    Topics: Animals; Avian Proteins; beta-Naphthoflavone; Cell Line; Chickens; Clotrimazole; Colforsin; Constitutive Androstane Receptor; Cyclic AMP; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Glutethimide; Growth Inhibitors; Hormone Antagonists; Humans; Metyrapone; Mifepristone; Okadaic Acid; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Signal Transduction; Trans-Activators; Transcription Factors

2001
A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:8

    Topics: Animals; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Duodenum; Enzyme Induction; Female; Firefly Luciferin; Genes, Reporter; Humans; Injections, Intraperitoneal; Kidney; Liver; Luciferases; Luminescent Measurements; Male; Mice; Mice, Transgenic; Models, Animal; Pregnenolone Carbonitrile; Sex Factors; Transcription, Genetic

2003