Compounds > pregnenolone carbonitrile
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pregnenolone carbonitrile and chloramphenicol

pregnenolone carbonitrile has been researched along with chloramphenicol in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Graves, PE; Halpert, J; Kaminsky, LS1
Balfour, C; Dunbar, D; Halpert, J; Kaminsky, LS; Miller, NE; Morgan, ET1
Chen, C; Klaassen, CD; Staudinger, JL1

Other Studies

4 other study(ies) available for pregnenolone carbonitrile and chloramphenicol

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Evidence for functional and structural multiplicity of pregnenolone-16 alpha-carbonitrile-inducible cytochrome P-450 isozymes in rat liver microsomes.
    Biochemistry, 1987, Jun-30, Volume: 26, Issue:13

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chloramphenicol; Collodion; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Female; Isoenzymes; Male; Microsomes, Liver; Oxygenases; Pregnenolone Carbonitrile; Protein Conformation; Rats; Rats, Inbred Strains; Steroid Hydroxylases

1987
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo.
    Molecular pharmacology, 1985, Volume: 28, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chloramphenicol; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Testosterone; Warfarin

1985
Nuclear receptor, pregname X receptor, is required for induction of UDP-glucuronosyltranferases in mouse liver by pregnenolone-16 alpha-carbonitrile.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:7

    Topics: Administration, Oral; Animals; Bilirubin; Chloramphenicol; Enzyme Induction; Food; Glucuronosyltransferase; Male; Mice; Mice, Mutant Strains; Microsomes, Liver; Naphthols; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Thyroxine; Time Factors; Triiodothyronine; Up-Regulation

2003