pregnenolone carbonitrile has been researched along with chenodeoxycholic acid in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anisfeld, AM; Edwards, PA; Goodwin, B; Jones, SA; Kast, HR; Kliewer, S; Stoltz, CM; Tarr, PT; Tontonoz, P; Willson, TM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Akase, T; Gonzalez, FJ; Kitada, H; Matsuda, Y; Miyata, M; Nagata, K; Shimada, M; Tsuchiya, H; Yamazoe, Y | 1 |
| Back, DJ; Martin, P; Owen, A; Riley, R | 1 |
4 other study(ies) available for pregnenolone carbonitrile and chenodeoxycholic acid
| Article | Year |
|---|---|
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
Topics: Animals; Base Sequence; Bile Acids and Salts; Blotting, Northern; Cell Line; Cell Nucleus; Cells, Cultured; Constitutive Androstane Receptor; DNA-Binding Proteins; Drug Resistance, Multiple; Genes, Reporter; Hepatocytes; Humans; Isoxazoles; Ligands; Liver; Membrane Transport Proteins; Mice; Models, Biological; Molecular Sequence Data; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Nucleic Acid Hybridization; Phenobarbital; Pregnane X Receptor; Promoter Regions, Genetic; Protein Binding; Protein Transport; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Signal Transduction; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 2002 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase.
Topics: Animals; Cells, Cultured; Chenodeoxycholic Acid; DNA-Binding Proteins; Down-Regulation; Female; Gene Expression Regulation, Enzymologic; Humans; Lithocholic Acid; Liver; Mice; Pregnenolone Carbonitrile; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sulfotransferases; Transcription Factors | 2006 |
Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.
Topics: Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Caco-2 Cells; Cell Culture Techniques; Cells, Cultured; Chenodeoxycholic Acid; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Induction; Epithelial Cells; Hepatocytes; Humans; Intestinal Mucosa; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Research Design; Rifampin; RNA, Messenger; Transcription Factors; Up-Regulation | 2008 |