Compounds > pregnenolone carbonitrile
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pregnenolone carbonitrile and bilirubin

pregnenolone carbonitrile has been researched along with bilirubin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brookman, S; Kourounakis, P; Lykissas, ED1
Klaassen, CD1
Solymoss, B; Zsigmond, G2
Adaikan, PG; Karim, SM; Kottegoda, SR1
Kourounakis, PN; Rekka, E1
Chen, C; Klaassen, CD; Staudinger, JL1

Other Studies

7 other study(ies) available for pregnenolone carbonitrile and bilirubin

ArticleYear
Effect of pregnenolone-16 alpha-carbonitrile on bilirubin-and sulfobromophthalein-binding to hepatic Y and Z proteins in the rat.
    Pharmacology, 1978, Volume: 16, Issue:4

    Topics: Animals; Bilirubin; Female; Liver; Pregnenolone Carbonitrile; Protein Binding; Rats; Sulfobromophthalein

1978
Effect of microsomal enzyme inducers on the biliary excretion of an exogenous load of bilirubin in newborn rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 153, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Bile; Bilirubin; Enzyme Induction; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone

1976
Effect of microsomal enzyme inducers on the liver changes produced by common bile-duct ligature.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 147, Issue:2

    Topics: Animals; Bilirubin; Common Bile Duct; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Enzyme Induction; Female; Glucuronosyltransferase; Hepatomegaly; Ligation; Liver; Liver Cirrhosis, Biliary; Microsomes, Liver; NADH, NADPH Oxidoreductases; Organ Size; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone

1974
Effect of various steroids on the hepatic glucuronidation and biliary excretion of bilirubin.
    Canadian journal of physiology and pharmacology, 1973, Volume: 51, Issue:5

    Topics: Animals; Bile; Bile Pigments; Bilirubin; Body Weight; Female; Glucuronates; Hexosyltransferases; Hydrocortisone; Kinetics; Liver; Microsomes, Liver; Organ Size; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone

1973
Effect of pregnenolone--16 alpha-carbonitrile (PCN) on bilirubin clearance in man.
    British journal of clinical pharmacology, 1981, Volume: 11, Issue:1

    Topics: Adult; Bilirubin; Enzyme Induction; Humans; Male; Metabolic Clearance Rate; Pregnenolone Carbonitrile

1981
Effect of spironolactone on dimethyl mercury toxicity. A possible molecular mechanism.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:10

    Topics: Alanine Transaminase; Animals; Bilirubin; Blood Urea Nitrogen; Body Weight; Ethylmorphine-N-Demethylase; Female; Methylmercury Compounds; Mutagens; Nervous System Diseases; Neuritis; Organ Size; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Spironolactone; Zoxazolamine

1994
Nuclear receptor, pregname X receptor, is required for induction of UDP-glucuronosyltranferases in mouse liver by pregnenolone-16 alpha-carbonitrile.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:7

    Topics: Administration, Oral; Animals; Bilirubin; Chloramphenicol; Enzyme Induction; Food; Glucuronosyltransferase; Male; Mice; Mice, Mutant Strains; Microsomes, Liver; Naphthols; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Thyroxine; Time Factors; Triiodothyronine; Up-Regulation

2003