Compounds > pregnenolone
Page last updated: 2024-08-20

pregnenolone and tamoxifen

pregnenolone has been researched along with tamoxifen in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellavance, E; Luu-The, V; Poirier, D1
Li, PS1
Brinkmann, AO; Leemborg, FG; van der Molen, HJ1
Catt, KJ; Dehejia, A; Dufau, ML; Nozu, K; Zawistowich, L1
Hsueh, AJ; Jia, XC; Jones, PB; Welsh, TH; Zhuang, LZ1
Catt, KJ; Dufau, ML; Nozu, K1
Santen, RJ; Santner, SJ1
Balasinor, N; Gill-Sharma, MK; Juneja, HS; Maitra, A; Parte, P1
Duffel, MW; Qin, X; Squirewell, EJ1

Other Studies

9 other study(ies) available for pregnenolone and tamoxifen

ArticleYear
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
In vitro effects of estradiol, diethylstilbestrol and tamoxifen on testosterone production by purified pig Leydig cells.
    The Chinese journal of physiology, 1991, Volume: 34, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Animals; Colforsin; Cyclic AMP; Diethylstilbestrol; Estradiol; Hydroxyprogesterones; Leydig Cells; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Radioimmunoassay; Swine; Tamoxifen; Testosterone

1991
hCG-induced inhibition of testicular steroidogenesis: an oestradiol-mediated process?
    Molecular and cellular endocrinology, 1981, Volume: 24, Issue:1

    Topics: Animals; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Estradiol; Leydig Cells; Male; Pregnenolone; Rats; Receptors, Cell Surface; Tamoxifen; Testosterone; Time Factors

1981
Gonadotropin-induced desensitization of Leydig cells in vivo and in vitro: estrogen action in the testis.
    Annals of the New York Academy of Sciences, 1982, Volume: 383

    Topics: Animals; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP; Cytochrome P-450 Enzyme System; Estradiol; Estrogens; Kinetics; Leydig Cells; Male; Pregnenolone; Protein Biosynthesis; Receptors, Cell Surface; Receptors, Estrogen; Receptors, LH; Tamoxifen; Testosterone

1982
Disparate effects of triphenylethylene antiestrogens on estrogen and progestin biosyntheses by cultured rat granulosa cells.
    Endocrinology, 1984, Volume: 115, Issue:4

    Topics: Animals; Aromatase; Clomiphene; Diethylstilbestrol; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Granulosa Cells; Hydroxyprogesterones; Nafoxidine; Pregnenolone; Progesterone; Progestins; Pyrrolidines; Rats; Rats, Inbred Strains; Tamoxifen

1984
Estradiol receptor-mediated regulation of steroidogenesis in gonadotropin-desensitized Leydig cells.
    The Journal of biological chemistry, 1981, Feb-25, Volume: 256, Issue:4

    Topics: Animals; Cell Nucleus; Chorionic Gonadotropin; Cytosol; Gonadotropin-Releasing Hormone; Kinetics; Leydig Cells; Male; Pregnenolone; Rats; Receptors, Estradiol; Receptors, Estrogen; Tamoxifen; Testis; Testosterone

1981
Inhibition of estrone sulfatase and 17 beta-hydroxysteroid dehydrogenase by antiestrogens.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:5

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding, Competitive; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Polyunsaturated Alkamides; Pregnenolone; Rats; Rats, Sprague-Dawley; Sulfatases; Tamoxifen

1993
Temporal effect of tamoxifen on cytochrome P450 side chain cleavage gene expression and steroid concentration in adult male rats.
    The Journal of steroid biochemistry and molecular biology, 2002, Volume: 82, Issue:4-5

    Topics: Administration, Oral; Androgens; Animals; Cholesterol; Cytochrome P-450 Enzyme System; Dihydrotestosterone; DNA Primers; Down-Regulation; Estradiol; Estrogen Antagonists; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Organ Size; Pregnenolone; Progesterone; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen; Testis; Testosterone

2002
Endoxifen and other metabolites of tamoxifen inhibit human hydroxysteroid sulfotransferase 2A1 (hSULT2A1).
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:11

    Topics: Catalysis; Dehydroepiandrosterone; Enzyme Inhibitors; Humans; Pregnenolone; Proton Magnetic Resonance Spectroscopy; Sulfotransferases; Tamoxifen

2014