pregnenolone has been researched along with pentobarbital in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (42.86) | 18.7374 |
| 1990's | 12 (42.86) | 18.2507 |
| 2000's | 3 (10.71) | 29.6817 |
| 2010's | 1 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dunn, WJ; Grigoras, S; Koehler, MG | 1 |
| Caron, G; Ermondi, G | 1 |
| Bowers, BJ; Wehner, JM | 1 |
| Allen, PM; Melchior, CL | 1 |
| Mienville, JM; Vicini, S | 1 |
| Baulieu, EE; Bluet-Pajot, MT; Majewska, MD; Robel, P | 1 |
| Majewska, MD; Mienville, JM; Vicini, S | 1 |
| Holzbauer, M; Newport, HM | 1 |
| Fleming, N; Genther, G; Gyermek, L | 1 |
| Solymoss, B; Toth, S; Werringloer, J | 1 |
| Brown-Grant, K | 1 |
| Barraclough, CA; Collu, R; Martini, L; Massa, R | 1 |
| Eik-Nes, KB; Tcholakian, RK | 1 |
| Prabhu, VK; Weisz, J | 1 |
| Uilenbroek, JT; van der Linden, R; Woutersen, PJ | 1 |
| Dartois, E; Fillion, G; Haour, F; Moyse, E; Vincens, M | 1 |
| Abayasekara, DR; Purdy, SJ; Whitehouse, BJ | 1 |
| Matsumoto, K; Ojima, K; Watanabe, H | 1 |
| Feltz, P; Poisbeau, P; Schlichter, R | 1 |
| Matsumoto, K; Nguyen, TT; Watanabe, H; Yamasaki, K | 1 |
| Castel, H; Cazin, L; Le Foll, F; Louiset, E; Vaudry, H | 1 |
| Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J | 1 |
| Akhondzadeh, S; Stone, TW | 1 |
| Carter, RB; Edgar, DM; Fick, DB; Gee, KW; Hogenkamp, DJ; Lan, NC; Seidel, WF; Vanover, KE | 1 |
| Dong, E; Matsumoto, K; Watanabe, H | 1 |
| Akk, G; Bracamontes, J; Steinbach, JH | 1 |
| Simmonds, MA; Sooksawate, T | 1 |
| Bright, DP; Seljeset, S; Smart, TG; Thomas, P | 1 |
28 other study(ies) available for pregnenolone and pentobarbital
| Article | Year |
|---|---|
The role of solvent-accessible surface area in determining partition coefficients.
Topics: Diffusion; Solubility; Solvents; Structure-Activity Relationship | 1987 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Biochemical and behavioral effects of steroids on GABAA receptor function in long- and short-sleep mice.
Topics: Anesthetics; Animals; Behavior, Animal; Brain Chemistry; Chlorides; Desoxycorticosterone; Ethanol; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Pentobarbital; Pregnanediones; Pregnenolone; Receptors, GABA-A; Sleep; Species Specificity; Steroids | 1992 |
Interaction of pregnanolone and pregnenolone sulfate with ethanol and pentobarbital.
Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pentobarbital; Pregnanolone; Pregnenolone; Seizures; Sleep; Time Factors | 1992 |
Pregnenolone sulfate antagonizes GABAA receptor-mediated currents via a reduction of channel opening frequency.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorides; Ion Channels; Membrane Potentials; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnenolone; Rats; Receptors, GABA-A | 1989 |
Pregnenolone sulfate antagonizes barbiturate-induced hypnosis.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Hypnosis, Anesthetic; Injections, Intraperitoneal; Injections, Intraventricular; Male; Pentobarbital; Pregnenolone; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1989 |
Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Pentobarbital; Pregnenolone; Rats; Steroids | 1988 |
Adrenal secretion rates and adrenal tissue concentrations of pregnenolone, progesterone, 11 beta OH-androstenedione and some other steroids in young pigs and dogs.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Animals; Blood Volume; Chloralose; Corticosterone; Dogs; Hydrocortisone; Indoles; Nephrectomy; Pentobarbital; Pregnenolone; Progesterone; Secretory Rate; Stress, Physiological; Swine | 1969 |
Some effects of progesterone and related steroids on the central nervous system.
Topics: Animals; Arousal; Avoidance Learning; Behavior, Animal; Brain; Cats; Electric Stimulation; Electroencephalography; Evoked Potentials; Haplorhini; Hippocampus; Hypothalamus; Male; Mice; Pentobarbital; Posture; Pregnanediol; Pregnanediones; Pregnenolone; Progesterone; Rats; Reflex; Reticular Formation; Sleep; Steroids; Thalamus | 1967 |
The influence of pregnenolone-16 -carbonitrile on hepatic mixed-function oxygenases.
Topics: Animals; Carbon Isotopes; Cytochromes; Enzyme Induction; Female; Half-Life; Liver; Metabolic Clearance Rate; Microsomes, Liver; NADP; Nitriles; Organ Size; Oxidoreductases; Pentobarbital; Pregnenolone; Proteins; Rats; Spironolactone; Stimulation, Chemical | 1971 |
Steroid hormone administration and gonadotrophin secretion in the gonadectomized rat.
Topics: Animals; Castration; Dihydrotestosterone; Estradiol; Estrus; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Ovulation; Pentobarbital; Pregnancy; Pregnanediones; Pregnenolone; Progesterone; Rats; Testosterone; Time Factors | 1974 |
Temporal interrelationships between plasma LH, ovarian secretion rates and peripheral plasma progestin concentrations in the rat: effects of Nembutal and exogenous gonadotropins.
Topics: Animals; Chromatography, Gas; Chromatography, Thin Layer; Drug Synergism; Estrus; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Ovary; Pentobarbital; Pregnancy; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Secretory Rate; Stimulation, Chemical; Time Factors; Veins | 1971 |
5 -pregnenolone and testosterone in spermatic venous blood of anesthetized dogs.
Topics: Animals; Chromatography, Gas; Chromatography, Thin Layer; Depression, Chemical; Dogs; Male; Pentobarbital; Pregnenolone; Spermatic Cord; Stress, Physiological; Testis; Testosterone; Veins | 1971 |
Effect of blocking ovulation in the rat by pentobarbital on ovarian 3 beta-hydroxysteroid dehydrogenases: A histochemical study.
Topics: Androstanes; Animals; Corpus Luteum; Estrus; Fallopian Tubes; Female; Humans; Ovarian Follicle; Ovary; Ovulation; Oxidoreductases; Pentobarbital; Pregnancy; Pregnanediol; Pregnanes; Pregnenolone; Rats; Steroids; Sulfates | 1970 |
Changes in oestrogen biosynthesis in preovulatory rat follicles after blockage of ovulation with pentobarbitone sodium.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aldehyde-Lyases; Animals; Aromatase; Estradiol; Estrus; Female; In Vitro Techniques; Luteinizing Hormone; Ovarian Follicle; Ovulation; Pentobarbital; Pregnancy; Pregnenolone; Proestrus; Progesterone; Rats; Rats, Inbred Strains; Steroid 17-alpha-Hydroxylase | 1984 |
An autoradiographic study comparing the interactions of 3 alpha-OH-5 alpha-pregnan-20-one, pregnenolone sulfate and pentobarbital with [3S]-TBPS binding sites and their modulation by GABA in different structures of the rat brain.
Topics: Animals; Anti-Anxiety Agents; Autoradiography; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mesencephalon; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
Inhibition of corticosteroid production by sodium pentobarbitone in rat adrenocortical preparations.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Animals; Bucladesine; Cells, Cultured; Corticosterone; Depression, Chemical; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Male; Pentobarbital; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains | 1993 |
Neurosteroidal modulation of social isolation-induced decrease in pentobarbital sleep in mice.
Topics: Adrenalectomy; Allosteric Regulation; Analysis of Variance; Animals; Anti-Anxiety Agents; Brain; Corticotropin-Releasing Hormone; Desoxycorticosterone; GABA-A Receptor Antagonists; Male; Methoxamine; Mice; Mice, Inbred Strains; Pentobarbital; Pregnenolone; Receptors, GABA-A; Sleep; Social Behavior; Social Isolation; Stress, Psychological; Yohimbine | 1996 |
Modulation of GABAA receptor-mediated IPSCs by neuroactive steroids in a rat hypothalamo-hypophyseal coculture model.
Topics: Animals; Animals, Newborn; Cells, Cultured; Electrophysiology; Female; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Membrane Potentials; Pentobarbital; Pregnancy; Pregnanes; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A | 1997 |
Majonoside-R2 reverses social isolation stress-induced decrease in pentobarbital sleep in mice: possible involvement of neuroactive steroids.
Topics: Animals; Corticotropin-Releasing Hormone; Desoxycorticosterone; Dose-Response Relationship, Drug; Ginsenosides; Hormone Antagonists; Hypnotics and Sedatives; Male; Mice; Pentobarbital; Peptide Fragments; Pregnenolone; Receptors, GABA-A; Saponins; Sleep; Social Isolation; Stress, Physiological | 1997 |
Electrophysiological effects of various neuroactive steroids on the GABA(A) receptor in pituitary melanotrope cells.
Topics: Animals; Cells, Cultured; Dehydroepiandrosterone; Electrophysiology; GABA Modulators; gamma-Aminobutyric Acid; Neurotransmitter Agents; Patch-Clamp Techniques; Pentobarbital; Pituitary Gland; Pregnenolone; Rana ridibunda; Receptors, GABA-A; Steroids | 1997 |
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem | 1998 |
Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate.
Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Synergism; Hippocampus; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Time Factors | 1998 |
Response-rate suppression in operant paradigm as predictor of soporific potency in rats and identification of three novel sedative-hypnotic neuroactive steroids.
Topics: Animals; Conditioning, Operant; Depression, Chemical; Dose-Response Relationship, Drug; Electroencephalography; Hypnotics and Sedatives; Male; Pentobarbital; Postural Balance; Pregnanolone; Pregnenolone; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Steroids; Triazolam; Zolpidem | 1999 |
Involvement of peripheral type of benzodiazepine receptor in social isolation stress-induced decrease in pentobarbital sleep in mice.
Topics: Animals; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; Hypnotics and Sedatives; Indoleacetic Acids; Isoquinolines; Male; Mice; Pentobarbital; Pregnenolone; Receptors, GABA-A; Sleep; Social Isolation; Stress, Physiological | 1999 |
Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunit.
Topics: Binding Sites; Cell Line; Estranes; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Ligands; Membrane Potentials; Mutagenesis; Nitriles; Patch-Clamp Techniques; Pentobarbital; Piperidines; Pregnenolone; Receptors, GABA-A; Transfection | 2001 |
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
Probing GABA
Topics: Animals; Binding Sites; Cell Line; Humans; Membrane Potentials; Mice; Neurotransmitter Agents; Pentobarbital; Picrotoxin; Pregnenolone; Protein Domains; Receptors, GABA-A; Recombinant Proteins | 2018 |