Page last updated: 2024-08-20

pregnenolone and n-methylaspartate

pregnenolone has been researched along with n-methylaspartate in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (45.95)	18.2507
2000's	14 (37.84)	29.6817
2010's	6 (16.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Berrino, L; Leyva, J; Maione, S; Rossi, F; Vitagliano, S	1
Farb, DH; Gibbs, TT; Wu, FS	1
Moss, RL; Wong, M	1
Bowlby, MR	1
Fahey, JM; Lindquist, DG; Miller, LG; Pritchard, GA	1
Baulieu, EE; Mahé, V; Monnet, FP; Robel, P	1
Irwin, RP; Lin, SZ; Paul, SM; Purdy, RH; Rogawski, MA	1
Bergeron, R; de Montigny, C; Debonnel, G	2
Chuang, DM; Gao, XM; Hough, CJ; Irwin, RP; Rogawski, MA	1
Richardson, CM; Wakerley, JB	2
Farb, DH; Gibbs, TT; Malayev, AA; Park-Chung, M; Purdy, RH; Wu, FS	1
Horiguchi, J; Kagaya, A; Takebayashi, M; Uchitomi, Y; Yamawaki, S; Yokota, N	1
Farb, DH; Gibbs, TT; Weaver, CE; Wu, FS	1
Cascio, C; De Leo, G; Guarneri, P; Guarneri, R; Piccoli, F; Piccoli, T; Russo, D; Sciuto, V	1
Juhng, KN; Kirkby, RD; Kokate, TG; Llamas, J; Rogawski, MA; Yamaguchi, S	1
Browning, MD; Costa, ET; Ferreira, VM; Frausto, S; Meyer, DA; Olivera, DS; Savage, DD; Soto, EE; Valenzuela, CF	1
Bidziński, A; Członkowska, AI; Krzaścik, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J	1
Hojo, Y; Kawato, S; Kimoto, T	1
Hattori, TA; Kawato, S; Kimoto, T; Takahashi, T; Tanabe, N; Yasumatsu, N	1
Enami, T; Furukawa, A; Harada, N; Hattori, TA; Hojo, Y; Ishii, HT; Janssen, WG; Kawato, S; Kimoto, T; Kominami, S; Morrison, JH; Mukai, H; Suzuki, K	1
Bidziński, A; Członkowska, AI; Krzaścik, P; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Szyndler, J; Taracha, E; Turzyńska, D; Walkowiak, J; Wisłowska, A; Zienowicz, M	1
Monnet, FP; Morin-Surun, MP; Schumacher, M; Sliwinski, A	1
Leatherland, JF; Lin, L; Renaud, R	1
Akwa, Y; Baulieu, EE; El-Etr, M; Schumacher, M	1
Chen, L; Furuya, K; Miyamoto, Y; Mori, N; Sokabe, M	1
Cheng, ZX; Dong, Y; Dong, YL; Ma, L; Qi, YJ; Wang, ZM; Wu, PY; Zheng, P; Zhu, Y; Zhu, YH	1
Farb, DH; Gibbs, TT; Whittaker, MT	1
Farb, DH; Gibbs, TT; Janis, GC; Pierce, RC; Sadri-Vakili, G	1
Budziszewska, B; Jantas, D; Lason, W; Leskiewicz, M	1
Akwa, Y; Covey, DF; Krishnan, K; Moricard, Y; Petit, GH; Rondi-Reig, L; Tobin, C	1
Agustí, A; Cauli, O; Felipo, V; González-Usano, A	1
Vicini, S	1
Dhanasekaran, S; Perumal, MB	1
Farb, DH; Gibbs, TT; Jang, MK; Kostakis, E; Martin, SC; Richards, KG; Russek, SJ; Smith, C	1
Huettner, JE; Lopez, MN; Wilding, TJ	1

Reviews

1 review(s) available for pregnenolone and n-methylaspartate

Article	Year
The FGIN period: electrophysiological studies. Pharmacological research, 2011, Volume: 64, Issue:4 Topics: Animals; Brain; Electrophysiology; gamma-Aminobutyric Acid; History, 20th Century; Humans; N-Methylaspartate; Neuropharmacology; Patch-Clamp Techniques; Pregnenolone; Receptors, Glutamate	2011

Other Studies

36 other study(ies) available for pregnenolone and n-methylaspartate

Article	Year
Pregnenolone sulfate increases the convulsant potency of N-methyl-D-aspartate in mice. European journal of pharmacology, 1992, Sep-04, Volume: 219, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Pregnenolone; Receptors, N-Methyl-D-Aspartate; Seizures	1992
Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor. Molecular pharmacology, 1991, Volume: 40, Issue:3 Topics: Allosteric Regulation; Animals; Cells, Cultured; Chick Embryo; N-Methylaspartate; Pregnenolone; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord	1991
Patch-clamp analysis of direct steroidal modulation of glutamate receptor-channels. Journal of neuroendocrinology, 1994, Volume: 6, Issue:3 Topics: Animals; Estradiol; Female; Hippocampus; In Vitro Techniques; Ion Channels; Kainic Acid; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pregnenolone; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Steroids	1994
Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons. Molecular pharmacology, 1993, Volume: 43, Issue:5 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electrophysiology; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine	1993
Pregnenolone sulfate potentiation of NMDA-mediated increases in intracellular calcium in cultured chick cortical neurons. Brain research, 1995, Jan-16, Volume: 669, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Fura-2; Glycine; N-Methylaspartate; Nimodipine; Pregnenolone; Spermine	1995
Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America, 1995, Apr-25, Volume: 92, Issue:9 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Guanidines; Haloperidol; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ovariectomy; Pertussis Toxin; Piperazines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stereotaxic Techniques; Virulence Factors, Bordetella	1995
Steroid potentiation and inhibition of N-methyl-D-aspartate receptor-mediated intracellular Ca++ responses: structure-activity studies. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2 Topics: Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Hippocampus; N-Methylaspartate; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1994
Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Feb-01, Volume: 16, Issue:3 Topics: Animals; Anisoles; Dehydroepiandrosterone; Drug Synergism; Female; Guanidines; Haloperidol; Hippocampus; Iontophoresis; Ligands; Male; N-Methylaspartate; Pertussis Toxin; Pregnenolone; Progesterone; Propylamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spiperone; Virulence Factors, Bordetella	1996
Carbamazepine inhibition of N-methyl-D-aspartate-evoked calcium influx in rat cerebellar granule cells. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1 Topics: Animals; Anticonvulsants; Calcium; Carbamazepine; Cerebellum; Cytoplasmic Granules; Drug Synergism; Glycine; Intracellular Fluid; N-Methylaspartate; Potassium Chloride; Pregnenolone; Rats	1996
Potentiation by dehydroepiandrosterone of the neuronal response to N-methyl-D-aspartate in the CA3 region of the rat dorsal hippocampus: an effect mediated via sigma receptors. The Journal of endocrinology, 1996, Volume: 150 Suppl Topics: Acetylcholine; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Synergism; Female; Hippocampus; Male; N-Methylaspartate; Ovariectomy; Pregnenolone; Progesterone; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, sigma; Stimulation, Chemical; Testosterone	1996
The neurosteroid pregnenolone sulphate enhances NMDA-induced phasic firing of vasopressin neurones in the rat supraoptic nucleus. Neuroscience letters, 1997, Apr-25, Volume: 226, Issue:2 Topics: Animals; Dehydroepiandrosterone Sulfate; Drug Synergism; Evoked Potentials; Female; Hypothalamus; In Vitro Techniques; N-Methylaspartate; Neurons; Picrotoxin; Pregnenolone; Rats; Rats, Wistar; Supraoptic Nucleus; Time Factors; Vasopressins	1997
Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids. Molecular pharmacology, 1997, Volume: 52, Issue:6 Topics: Animals; Arachidonic Acid; Binding Sites; Binding, Competitive; Cells, Cultured; Chick Embryo; Hippocampus; N-Methylaspartate; Neurons; Oxidation-Reduction; Polyamines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Structure-Activity Relationship; Xenopus laevis	1997
Differential regulation by pregnenolone sulfate of intracellular Ca2+ increase by amino acids in primary cultured rat cortical neurons. Neurochemistry international, 1998, Volume: 32, Issue:2 Topics: Acetylcholine; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; gamma-Aminobutyric Acid; N-Methylaspartate; Neurons; Potassium; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A	1998
Pregnenolone sulfate exacerbates NMDA-induced death of hippocampal neurons. Brain research, 1998, Aug-24, Volume: 803, Issue:1-2 Topics: Aniline Compounds; Animals; Calcimycin; Calcium; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Fetus; Hippocampus; N-Methylaspartate; Neurons; Potassium; Pregnenolone; Rats; Receptors, N-Methyl-D-Aspartate; Xanthenes	1998
Supraoptic oxytocin and vasopressin neurones show differential sensitivity to the neurosteroid pregnenolone sulphate. Journal of neuroendocrinology, 1998, Volume: 10, Issue:11 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Female; Glutamic Acid; N-Methylaspartate; Neurons; Oxytocin; Pregnenolone; Rats; Rats, Wistar; Supraoptic Nucleus; Vasopressins	1998
Pregnenolone sulfate modulates NMDA receptors, inducing and potentiating acute excitotoxicity in isolated retina. Journal of neuroscience research, 1998, Dec-15, Volume: 54, Issue:6 Topics: Animals; Dizocilpine Maleate; Drug Synergism; L-Lactate Dehydrogenase; Male; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Pregnenolone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina	1998
Convulsant actions of the neurosteroid pregnenolone sulfate in mice. Brain research, 1999, Jun-12, Volume: 831, Issue:1-2 Topics: Animals; Convulsants; Disease Susceptibility; Drug Synergism; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Pregnenolone; Receptors, GABA-A; Seizures	1999
Fetal alcohol exposure alters neurosteroid modulation of hippocampal N-methyl-D-aspartate receptors. The Journal of biological chemistry, 2000, Dec-08, Volume: 275, Issue:49 Topics: Animals; Cells, Cultured; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Glycine; Hippocampus; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pregnancy; Pregnenolone; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate	2000
The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol. Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:2 Topics: Animals; Bicuculline; Central Nervous System Depressants; Convulsants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Picrotoxin; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Reflex; Seizures; Sleep; Steroids	2000
Histological and metabolism analysis of P450 expression in the brain. Methods in enzymology, 2002, Volume: 357 Topics: Animals; Cell Fractionation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estradiol; Excitatory Amino Acid Agonists; Female; Hippocampus; Immunohistochemistry; Male; N-Methylaspartate; Ovary; Pregnenolone; Radioimmunoassay; Rats; Rats, Wistar; Testis	2002
Corticosterone acutely prolonged N-methyl-d-aspartate receptor-mediated Ca2+ elevation in cultured rat hippocampal neurons. Journal of neurochemistry, 2002, Volume: 83, Issue:6 Topics: Androstanols; Animals; Calcium; Calcium Signaling; Cells, Cultured; Corticosterone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Hippocampus; Hormone Antagonists; Membrane Potentials; Mifepristone; Mitochondria; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate	2002
Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons. Proceedings of the National Academy of Sciences of the United States of America, 2004, Jan-20, Volume: 101, Issue:3 Topics: Animals; Aromatase; Calcium Signaling; Cholesterol; Dehydroepiandrosterone; Estradiol; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Microscopy, Immunoelectron; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Wistar; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Testosterone	2004
Pregnenolone sulfate potentiates the effects of NMDA on hippocampal alanine and dopamine. Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:4 Topics: Alanine; Amino Acids; Animals; Bicuculline; Convulsants; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Male; Mice; Microinjections; N-Methylaspartate; Picrotoxin; Pregnenolone; Seizures	2004
Pregnenolone sulfate enhances long-term potentiation in CA1 in rat hippocampus slices through the modulation of N-methyl-D-aspartate receptors. Journal of neuroscience research, 2004, Dec-01, Volume: 78, Issue:5 Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Pregnenolone; Rats; Receptors, N-Methyl-D-Aspartate	2004
Effect of glutamate and somatostatin-14 on basal and cAMP-stimulated steroidogenesis by rainbow trout (Oncorhynchus mykiss) ovarian follicles, in vitro. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2005, Volume: 140, Issue:4 Topics: Animals; Cyclic AMP; Estradiol; Female; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oncorhynchus mykiss; Ovarian Follicle; Pregnenolone; Somatostatin; Steroids; Testosterone	2005
The neuroactive steroid pregnenolone sulfate stimulates the release of gonadotropin-releasing hormone from GT1-7 hypothalamic neurons, through N-methyl-D-aspartate receptors. Endocrinology, 2006, Volume: 147, Issue:6 Topics: Animals; Cells, Cultured; Glutamic Acid; Glycine; Gonadotropin-Releasing Hormone; Hypothalamus; Mice; N-Methylaspartate; Pregnenolone; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Vesicular Glutamate Transport Protein 2	2006
PREGS induces LTP in the hippocampal dentate gyrus of adult rats via the tyrosine phosphorylation of NR2B coupled to ERK/CREB [corrected] signaling. Journal of neurophysiology, 2007, Volume: 98, Issue:3 Topics: Animals; Calcium; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Electrophysiology; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Phosphorylation; Pregnenolone; Rats; Receptors, N-Methyl-D-Aspartate	2007
Neuroactive steroid pregnenolone sulphate inhibits long-term potentiation via activation of alpha2-adrenoreceptors at excitatory synapses in rat medial prefrontal cortex. The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:5 Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Prefrontal Cortex; Pregnenolone; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Synapses	2008
Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum. Journal of neurochemistry, 2008, Volume: 107, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Microscopy, Electron, Scanning; N-Methylaspartate; Potassium Chloride; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tritium; Valine	2008
Nanomolar concentrations of pregnenolone sulfate enhance striatal dopamine overflow in vivo. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:3 Topics: Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; N-Methylaspartate; Pregnenolone; Rats; Receptors, sigma; Signal Transduction	2008
Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59, Issue:3 Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Death; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Excitatory Amino Acids; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phosphoinositide-3 Kinase Inhibitors; Pregnanolone; Pregnenolone; Reactive Oxygen Species; Staurosporine; Steroids	2008
Pregnenolone sulfate and its enantiomer: differential modulation of memory in a spatial discrimination task using forebrain NMDA receptor deficient mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2011, Volume: 21, Issue:2 Topics: Animals; Hippocampus; Male; Memory; Mice; Mice, Knockout; N-Methylaspartate; Pregnenolone; Prosencephalon; Receptors, N-Methyl-D-Aspartate; Space Perception; Stereoisomerism; Steroids	2011
Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo. Neuroscience, 2011, Sep-08, Volume: 190 Topics: Animals; Cerebellum; Cyclic GMP; Dehydroepiandrosterone; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Signal Transduction	2011
HIV associated dementia: role for neurosteroids. Medical hypotheses, 2012, Volume: 78, Issue:5 Topics: AIDS Dementia Complex; Apoptosis; Brain; Calcium Signaling; Humans; MAP Kinase Signaling System; Microtubule-Associated Proteins; Models, Neurological; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Pregnenolone; Steroids; Synapses	2012
The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism. Molecular pharmacology, 2013, Volume: 84, Issue:2 Topics: Animals; Calcium; Cells, Cultured; Exocytosis; GTP-Binding Proteins; N-Methylaspartate; Neurons; Oocytes; Pregnenolone; Protein Kinase C; Protein Transport; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Xenopus laevis	2013
Chimeric Glutamate Receptor Subunits Reveal the Transmembrane Domain Is Sufficient for NMDA Receptor Pore Properties but Some Positive Allosteric Modulators Require Additional Domains. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 08-24, Volume: 36, Issue:34 Topics: Allosteric Regulation; Animals; Arachidonic Acid; Calcium; Dimerization; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Excitatory Amino Acid Agonists; Green Fluorescent Proteins; HEK293 Cells; Humans; Hydroxycholesterols; Kainic Acid; Membrane Potentials; Models, Molecular; N-Methylaspartate; Patch-Clamp Techniques; Pregnenolone; Protein Domains; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Transfection	2016