pregnenolone has been researched along with kainic acid in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Moss, RL; Wong, M | 1 |
| Bowlby, MR | 1 |
| Chen, SC; Wu, FS | 1 |
| Farb, DH; Gibbs, TT; Malayev, A; Russek, SJ; Yaghoubi, N | 1 |
| Chen, L; Sokabe, M | 1 |
| Chia, WJ; Farooqui, AA; Jenner, AM; Ong, WY | 1 |
| Cho, JH; Choi, BJ; Choi, IS; Jang, IS; Lee, KH; Lee, MG; Park, HM | 1 |
| Huettner, JE; Lopez, MN; Wilding, TJ | 1 |
| Biagini, G; Costa, AM; Lucchi, C; Messina, S; Rustichelli, C; Senn, L | 1 |
9 other study(ies) available for pregnenolone and kainic acid
| Article | Year |
|---|---|
Patch-clamp analysis of direct steroidal modulation of glutamate receptor-channels.
Topics: Animals; Estradiol; Female; Hippocampus; In Vitro Techniques; Ion Channels; Kainic Acid; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pregnenolone; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Steroids | 1994 |
Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electrophysiology; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
Mechanism underlying the effect of pregnenolone sulfate on the kainate-induced current in cultured chick spinal cord neurons.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Chick Embryo; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channel Gating; Kainic Acid; Neurons; Patch-Clamp Techniques; Pregnenolone; Receptors, Kainic Acid; Spinal Cord | 1997 |
Neurosteroid modulation of recombinant ionotropic glutamate receptors.
Topics: Adrenal Cortex Hormones; Animals; Dose-Response Relationship, Drug; GluK2 Kainate Receptor; Kainic Acid; Microinjections; Neurotransmitter Agents; Oocytes; Pregnenolone; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; RNA, Complementary; Xenopus | 1998 |
Presynaptic modulation of synaptic transmission by pregnenolone sulfate as studied by optical recordings.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Analysis of Variance; Animals; Benzylidene Compounds; Bicuculline; Bungarotoxins; Calcium; Calcium Channel Blockers; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ethylenediamines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Haloperidol; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Pregnenolone; Presynaptic Terminals; Pyridines; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin; Time Factors | 2005 |
Changes in cytochrome P450 side chain cleavage expression in the rat hippocampus after kainate injury.
Topics: Animals; Blotting, Western; Cholesterol Side-Chain Cleavage Enzyme; Gas Chromatography-Mass Spectrometry; Hippocampus; Injections, Intraperitoneal; Kainic Acid; Kinetics; Pregnenolone; Rats; Rats, Wistar; Time Factors | 2008 |
Pregnenolone sulfate enhances spontaneous glutamate release by inducing presynaptic Ca2+-induced Ca2+ release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Cadmium Chloride; Calcium; Calcium Channel Blockers; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Neurons; Patch-Clamp Techniques; Piperazines; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin | 2010 |
Chimeric Glutamate Receptor Subunits Reveal the Transmembrane Domain Is Sufficient for NMDA Receptor Pore Properties but Some Positive Allosteric Modulators Require Additional Domains.
Topics: Allosteric Regulation; Animals; Arachidonic Acid; Calcium; Dimerization; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Excitatory Amino Acid Agonists; Green Fluorescent Proteins; HEK293 Cells; Humans; Hydroxycholesterols; Kainic Acid; Membrane Potentials; Models, Molecular; N-Methylaspartate; Patch-Clamp Techniques; Pregnenolone; Protein Domains; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Transfection | 2016 |
Augmentation of endogenous neurosteroid synthesis alters experimental status epilepticus dynamics.
Topics: 5-alpha-Dihydroprogesterone; Animals; Brain; Chromatography, Liquid; Dihydrotestosterone; Electrocorticography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neocortex; Neurosteroids; Pregnanolone; Pregnenolone; Progesterone; Rats; Receptors, GABA-A; Status Epilepticus; Tandem Mass Spectrometry; Time Factors | 2020 |