Page last updated: 2024-08-20

pregnenolone and gamma-aminobutyric acid

pregnenolone has been researched along with gamma-aminobutyric acid in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.17)	18.7374
1990's	18 (39.13)	18.2507
2000's	20 (43.48)	29.6817
2010's	5 (10.87)	24.3611
2020's	2 (4.35)	2.80

Authors

Authors	Studies
Barnard, EA; Darlison, MG; Harvey, RJ; Shingai, R; Zaman, SH	1
Farb, DH; Friedman, L; Gibbs, TT; Gyenes, M; Russek, SJ; Wu, FS	1
Miledi, R; Polenzani, L; Woodward, RM	1
Majewska, MD; Vaupel, DB	1
Majewska, MD; Mienville, JM; Vicini, S	1
Baulieu, EE; Corpéchot, C; Haug, M; Mayo, W; Perché, F; Robel, P; Simon, H; Young, J	1
Dartois, E; Fillion, G; Haour, F; Moyse, E; Vincens, M	1
Melchior, CL; Ritzmann, RF	1
Hauser, CA; Holsboer, F; Rupprecht, R; Wetzel, CH	1
Acosta-Burruel, M; Goodnough, DB; Hawkinson, JE; Kimbrough, CL; Wood, PL	1
Gillies, GE; Murray, HE	1
Feltz, P; Poisbeau, P; Schlichter, R	1
Castel, H; Cazin, L; Le Foll, F; Louiset, E; Vaudry, H	1
Gavish, M; Paz, L; Peter, Y; Pick, CG; Schreiber, S; Weizman, R	1
Kasparov, S; Kravitz, EA; Rahamimoff, R; Teschemacher, A	1
Chapell, R; Leidenheimer, NJ	1
Horiguchi, J; Kagaya, A; Takebayashi, M; Uchitomi, Y; Yamawaki, S; Yokota, N	1
Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J	1
Covey, DF; Mennerick, S; Shen, W; Zorumski, CF; Zorumski, EC	1
Covey, DF; Mennerick, S; Shen, W; Zorumski, CF	1
Biggio, G; Littera, M; Papi, G; Pisu, MG; Purdy, RH; Sanna, E; Serra, M; Tuveri, F; Usala, L	1
Beekman, M; Carter, RB; Dijkstra, D; Gasior, M; Ungard, JT; Witkin, JM	1
Frank, C; Sagratella, S	1
Akk, G; Bracamontes, J; Steinbach, JH	1
Melcangi, RC; Panzica, G	1
Jhangri, GS; Le Mellédo, JM; Semeniuk, T	1
Simmonds, MA; Sooksawate, T	1
Bertram, EH; Kapur, J; Mtchedlishvili, Z	1
Benz, A; Covey, DF; Eisenman, LN; Fields, C; Fu, T; He, Y; Mathews, J; Mennerick, S; Steinbach, JH; Wang, M; Zeng, CM; Zorumski, CF; Zorumski, E	1
Homanics, GE; Huguenard, JR; Huntsman, MM; Mihalek, RM; Porcello, DM	1
Harrison, MB; Kapur, J; Mtchedlishvili, Z; Sun, CS	1
Kapur, J; Mtchedlishvili, Z	1
Bäckström, T; Haage, D; Johansson, S	1
Arias, P; Hoijman, E; Howard, S; Jaliffa, CO; Rosenstein, RE; Salido, E; Sarmiento, MI	1
Bäckström, T; Johansson, IM; Lindblad, C; Rahman, M; Wang, MD	1
Boyd, KN; Grant, KA; Morrow, AL; Porcu, P	1
Bäckström, T; Borra, VB; Haage, D; Lundgren, P; Strömberg, J; Wang, MD	1
Akk, G; Bracamontes, J; Covey, DF; Li, P; Reichert, DE; Steinbach, JH	1
Bäckström, T; Haage, D; Lundgren, P; Strömberg, J; Taube, M; Wang, M	1
Boyd, KN; Kumar, S; Morrow, AL; O'Buckley, TK	1
Beaumont, M; Maccaferri, G	1
Agustí, A; Cauli, O; Felipo, V; González-Usano, A	1
Vicini, S	1
Mennerick, S; Taylor, AA; Zorumski, CF	1
Bright, DP; Liebowitz, S; Seljeset, S; Smart, TG	1
Ernst, M; Frølund, B; Krall, J; Mortensen, M; Shehata, MA; Smart, TG; Xu, Y	1

Reviews

3 review(s) available for pregnenolone and gamma-aminobutyric acid

Article	Year
Biosynthesis and assay of neurosteroids in rats and mice: functional correlates. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 53, Issue:1-6 Topics: Adrenalectomy; Aggression; Aging; Animals; Behavior, Animal; Dehydroepiandrosterone; Dihydrotestosterone; Female; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Lactation; Male; Memory; Mice; Orchiectomy; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley	1995
Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior. Dialogues in clinical neuroscience, 2006, Volume: 8, Issue:4 Topics: Alcohol Drinking; Animals; Brain Chemistry; Central Nervous System Depressants; Discrimination, Psychological; Ethanol; gamma-Aminobutyric Acid; Humans; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Pregnenolone; Steroids	2006
The FGIN period: electrophysiological studies. Pharmacological research, 2011, Volume: 64, Issue:4 Topics: Animals; Brain; Electrophysiology; gamma-Aminobutyric Acid; History, 20th Century; Humans; N-Methylaspartate; Neuropharmacology; Patch-Clamp Techniques; Pregnenolone; Receptors, Glutamate	2011

Other Studies

43 other study(ies) available for pregnenolone and gamma-aminobutyric acid

Article	Year
Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid. European journal of pharmacology, 1992, Apr-10, Volume: 225, Issue:4 Topics: Animals; Base Sequence; DNA; gamma-Aminobutyric Acid; Humans; Macromolecular Substances; Molecular Sequence Data; Oocytes; Polymerase Chain Reaction; Pregnanolone; Pregnenolone; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Xenopus laevis	1992
Steroid modulation of amino acid neurotransmitter receptors. Advances in biochemical psychopharmacology, 1992, Volume: 47 Topics: Animals; Cells, Cultured; Chick Embryo; Electrophysiology; Flunitrazepam; gamma-Aminobutyric Acid; Glutamates; Pregnenolone; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Steroids	1992
Effects of steroids on gamma-aminobutyric acid receptors expressed in Xenopus oocytes by poly(A)+ RNA from mammalian brain and retina. Molecular pharmacology, 1992, Volume: 41, Issue:1 Topics: Animals; Bicuculline; Brain; Cattle; Cerebral Cortex; gamma-Aminobutyric Acid; Membrane Potentials; Oocytes; Poly A; Pregnenolone; Rats; Receptors, GABA-A; Retina; RNA; Steroids; Transfection; Xenopus	1992
Steroid control of uterine motility via gamma-aminobutyric acidA receptors in the rabbit: a novel mechanism? The Journal of endocrinology, 1991, Volume: 131, Issue:3 Topics: Animals; Female; gamma-Aminobutyric Acid; Pregnanolone; Pregnenolone; Progesterone; Progestins; Rabbits; Receptors, GABA-A; Stimulation, Chemical; Uterine Contraction	1991
Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons. Neuroscience letters, 1988, Aug-01, Volume: 90, Issue:3 Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Pentobarbital; Pregnenolone; Rats; Steroids	1988
An autoradiographic study comparing the interactions of 3 alpha-OH-5 alpha-pregnan-20-one, pregnenolone sulfate and pentobarbital with [3S]-TBPS binding sites and their modulation by GABA in different structures of the rat brain. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:4 Topics: Animals; Anti-Anxiety Agents; Autoradiography; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mesencephalon; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A	1995
Pregnenolone and pregnenolone sulfate, alone and with ethanol, in mice on the plus-maze. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:4 Topics: Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pregnenolone; Stress, Psychological; Sulfates	1994
Allopregnanolone acts as an inhibitory modulator on alpha1- and alpha6-containing GABA-A receptors. Biochemical and biophysical research communications, 1996, Feb-15, Volume: 219, Issue:2 Topics: Animals; Anti-Anxiety Agents; Cell Line; Cell Membrane; Chloride Channels; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypothalamus; Kinetics; Membrane Potentials; Molecular Sequence Data; Muscimol; Neurons; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection	1996
Steroid inhibition of [3H]SR 95531 binding to the GABAA recognition site. European journal of pharmacology, 1996, May-23, Volume: 304, Issue:1-3 Topics: Allosteric Regulation; Androstanes; Animals; Azasteroids; Cell Membrane; Cerebral Cortex; Desoxycorticosterone; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pregnanolone; Pregnenolone; Protein Binding; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids	1996
Differential effects of neuroactive steroids on somatostatin and dopamine secretion from primary hypothalamic cell cultures. Journal of neuroendocrinology, 1997, Volume: 9, Issue:4 Topics: Animals; Bicuculline; Cells, Cultured; Dehydroepiandrosterone Sulfate; Dopamine; Drug Synergism; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Pregnanolone; Pregnenolone; Rats; Somatostatin	1997
Modulation of GABAA receptor-mediated IPSCs by neuroactive steroids in a rat hypothalamo-hypophyseal coculture model. The Journal of physiology, 1997, Apr-15, Volume: 500 ( Pt 2) Topics: Animals; Animals, Newborn; Cells, Cultured; Electrophysiology; Female; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Membrane Potentials; Pentobarbital; Pregnancy; Pregnanes; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A	1997
Electrophysiological effects of various neuroactive steroids on the GABA(A) receptor in pituitary melanotrope cells. European journal of pharmacology, 1997, Jul-23, Volume: 331, Issue:2-3 Topics: Animals; Cells, Cultured; Dehydroepiandrosterone; Electrophysiology; GABA Modulators; gamma-Aminobutyric Acid; Neurotransmitter Agents; Patch-Clamp Techniques; Pentobarbital; Pituitary Gland; Pregnenolone; Rana ridibunda; Receptors, GABA-A; Steroids	1997
Effect of the pregnane-related GABA-active steroid alphaxalone on mice performance in the staircase test. Brain research, 1997, Aug-08, Volume: 765, Issue:1 Topics: Alprazolam; Anesthetics; Animals; Anti-Inflammatory Agents; Corticosterone; Dose-Response Relationship, Drug; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Muscimol; Pregnanediones; Pregnanes; Pregnenolone; Psychomotor Performance	1997
Presynaptic action of the neurosteroid pregnenolone sulfate on inhibitory transmitter release in cultured hippocampal neurons. Brain research, 1997, Oct-24, Volume: 772, Issue:1-2 Topics: Animals; Cells, Cultured; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Neurons; Patch-Clamp Techniques; Pregnenolone; Presynaptic Terminals; Rats	1997
Effects of PKC activation and receptor desensitization on neurosteroid modulation of GABA(A) receptors. Brain research. Molecular brain research, 1997, Dec-15, Volume: 52, Issue:2 Topics: Animals; Anti-Anxiety Agents; Chloride Channels; Desoxycorticosterone; Enzyme Activation; Female; gamma-Aminobutyric Acid; Humans; Kinetics; Oocytes; Phorbol Esters; Pregnenolone; Protein Kinase C; Receptors, GABA-A; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Xenopus laevis	1997
Differential regulation by pregnenolone sulfate of intracellular Ca2+ increase by amino acids in primary cultured rat cortical neurons. Neurochemistry international, 1998, Volume: 32, Issue:2 Topics: Acetylcholine; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; gamma-Aminobutyric Acid; N-Methylaspartate; Neurons; Potassium; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A	1998
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jul-01, Volume: 18, Issue:13 Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem	1998
Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors. Neuropharmacology, 1999, Volume: 38, Issue:2 Topics: Animals; Chloride Channels; Dehydroepiandrosterone Sulfate; Female; gamma-Aminobutyric Acid; Macromolecular Substances; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Picrotoxin; Pregnenolone; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis	1999
Pregnenolone sulfate modulates inhibitory synaptic transmission by enhancing GABA(A) receptor desensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, May-15, Volume: 20, Issue:10 Topics: Animals; beta-Alanine; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pregnenolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Synaptic Transmission; Taurine	2000
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain. Journal of neurochemistry, 2000, Volume: 75, Issue:2 Topics: Animals; Anxiety; Brain; Cerebral Cortex; Conflict, Psychological; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Electroshock; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Oocytes; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Social Isolation; Steroids; Synaptosomes; Time Factors; Xenopus laevis	2000
Modification of behavioral effects of drugs in mice by neuroactive steroids. Psychopharmacology, 2000, Volume: 148, Issue:4 Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Convulsants; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Pentylenetetrazole; Pregnanolone; Pregnenolone; Psychotropic Drugs; Steroids; Synaptic Transmission	2000
Neuroprotective effects of allopregnenolone on hippocampal irreversible neurotoxicity in vitro. Progress in neuro-psychopharmacology & biological psychiatry, 2000, Volume: 24, Issue:7 Topics: Animals; Brain Ischemia; Calcium Channels; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Pregnenolone; Rats; Rats, Wistar	2000
Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunit. The Journal of physiology, 2001, May-01, Volume: 532, Issue:Pt 3 Topics: Binding Sites; Cell Line; Estranes; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Ligands; Membrane Potentials; Mutagenesis; Nitriles; Patch-Clamp Techniques; Pentobarbital; Piperidines; Pregnenolone; Receptors, GABA-A; Transfection	2001
Steroids in the nervous system: a Pandora's box? Trends in neurosciences, 2001, Volume: 24, Issue:6 Topics: Animals; Cholestenone 5 alpha-Reductase; gamma-Aminobutyric Acid; Humans; Nervous System Physiological Phenomena; Neuropeptides; Oxidoreductases; Pregnenolone; Receptors, GABA; Signal Transduction; Steroids	2001
Neuroactive steroid levels in patients with generalized anxiety disorder. The Journal of neuropsychiatry and clinical neurosciences, 2001,Summer, Volume: 13, Issue:3 Topics: Adult; Anxiety Disorders; Dehydroepiandrosterone; Female; gamma-Aminobutyric Acid; Humans; Male; Pregnanolone; Pregnenolone; Receptors, GABA-A	2001
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators. British journal of pharmacology, 2001, Volume: 134, Issue:6 Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A	2001
Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy. The Journal of physiology, 2001, Dec-01, Volume: 537, Issue:Pt 2 Topics: Animals; Anticonvulsants; Chronic Disease; Diazepam; Electric Conductivity; Epilepsy, Temporal Lobe; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Pregnanolone; Pregnenolone; Pyridines; Rats; Receptors, GABA-A; Zinc; Zolpidem	2001
3beta -hydroxypregnane steroids are pregnenolone sulfate-like GABA(A) receptor antagonists. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-01, Volume: 22, Issue:9 Topics: Amino Acid Substitution; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Flumazenil; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hydroxysteroids; Lorazepam; Oocytes; Patch-Clamp Techniques; Pregnanes; Pregnenolone; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship; Synapses; Xenopus laevis	2002
Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit. Journal of neurophysiology, 2003, Volume: 89, Issue:3 Topics: Anesthetics; Animals; Desoxycorticosterone; Evoked Potentials; Female; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neural Pathways; Pregnenolone; Receptors, GABA-A; Synapses; Thalamus	2003
Increased neurosteroid sensitivity of hippocampal GABAA receptors during postnatal development. Neuroscience, 2003, Volume: 118, Issue:3 Topics: Aging; Animals; Animals, Newborn; Cell Membrane; Cells, Cultured; Dentate Gyrus; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Male; Membrane Potentials; Neural Inhibition; Neurons; Pregnanolone; Pregnenolone; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Steroids; Up-Regulation	2003
A presynaptic action of the neurosteroid pregnenolone sulfate on GABAergic synaptic transmission. Molecular pharmacology, 2003, Volume: 64, Issue:4 Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; GTP-Binding Proteins; Hippocampus; Pertussis Toxin; Pregnenolone; Rats; Receptors, sigma; Sigma-1 Receptor; Synaptic Transmission	2003
Interaction between allopregnanolone and pregnenolone sulfate in modulating GABA-mediated synaptic currents in neurons from the rat medial preoptic nucleus. Brain research, 2005, Feb-01, Volume: 1033, Issue:1 Topics: Anesthetics; Animals; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Models, Neurological; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Preoptic Area; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission	2005
Effect of neurosteroids on the retinal gabaergic system and electroretinographic activity in the golden hamster. Journal of neurochemistry, 2005, Volume: 94, Issue:6 Topics: Animals; Anticonvulsants; Calcium Signaling; Corticosterone; Cricetinae; Cytochrome P-450 Enzyme System; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Mesocricetus; Neural Inhibition; Neural Pathways; Neurons; Pregnenolone; Presynaptic Terminals; Retina; Steroids; Synaptic Transmission; Synaptosomes; Vigabatrin	2005
Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte. European journal of pharmacology, 2006, Oct-10, Volume: 547, Issue:1-3 Topics: Androstane-3,17-diol; Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Pregnanediol; Pregnanes; Pregnenolone; Protein Subunits; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; RNA, Messenger; Steroids; Xenopus laevis; Zolpidem	2006
Neurosteroids 3beta, 20 (R/S)-pregnandiols decrease offset rate of the GABA-site activation at the recombinant GABA A receptor. European journal of pharmacology, 2008, May-31, Volume: 586, Issue:1-3 Topics: Animals; Binding Sites; Data Interpretation, Statistical; Electrophysiology; Female; gamma-Aminobutyric Acid; Oocytes; Patch-Clamp Techniques; Pregnanediol; Pregnenolone; Receptors, GABA-A; Recombinant Proteins; Stereoisomerism; Xenopus laevis	2008
Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids. Molecular pharmacology, 2008, Volume: 74, Issue:3 Topics: Amino Acid Substitution; Animals; Cell Line; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutant Proteins; Mutation; Piperidines; Pregnanetriol; Pregnanolone; Pregnenolone; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, GABA-A; Serine; Steroids; Tryptophan	2008
The effect of the neuroactive steroid 5beta-pregnane-3beta, 20(R)-diol on the time course of GABA evoked currents is different to that of pregnenolone sulphate. European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3 Topics: Animals; Electrophysiology; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Neurons; Patch-Clamp Techniques; Pregnanediol; Pregnenolone; Preoptic Area; Rats; Rats, Sprague-Dawley; Time Factors	2009
Chronic ethanol exposure produces tolerance to elevations in neuroactive steroids: mechanisms and reversal by exogenous ACTH. Journal of neurochemistry, 2010, Volume: 115, Issue:1 Topics: Adrenocorticotropic Hormone; Animals; Blotting, Western; Central Nervous System Depressants; Cyclic AMP-Dependent Protein Kinases; Diet; Drug Tolerance; Ethanol; gamma-Aminobutyric Acid; Immunoprecipitation; Male; Mitochondrial Membranes; Neurotransmitter Agents; Phosphoproteins; Phosphorylation; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley	2010
Is connexin36 critical for GABAergic hypersynchronization in the hippocampus? The Journal of physiology, 2011, Apr-01, Volume: 589, Issue:Pt 7 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbenoxolone; Connexins; Epilepsy; gamma-Aminobutyric Acid; Gap Junction delta-2 Protein; Gap Junctions; Hippocampus; In Vitro Techniques; Interneurons; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Patch-Clamp Techniques; Pregnenolone; Receptors, GABA-A	2011
Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo. Neuroscience, 2011, Sep-08, Volume: 190 Topics: Animals; Cerebellum; Cyclic GMP; Dehydroepiandrosterone; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Signal Transduction	2011
Phosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABAA receptor function. Psychopharmacology, 2014, Volume: 231, Issue:17 Topics: Animals; Female; gamma-Aminobutyric Acid; KCNQ1 Potassium Channel; Neurotransmitter Agents; Oocytes; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Picrates; Potassium Channels, Voltage-Gated; Pregnenolone; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Xenopus; Xenopus Proteins	2014
Pre- and postsynaptic modulation of hippocampal inhibitory synaptic transmission by pregnenolone sulphate. Neuropharmacology, 2023, 08-01, Volume: 233 Topics: Animals; gamma-Aminobutyric Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Neurosteroids; Pregnenolone; Rats; Receptors, GABA-A; Synaptic Transmission; TRPM Cation Channels	2023
Pregnenolone sulfate analogues differentially modulate GABA British journal of pharmacology, 2023, Volume: 180, Issue:19 Topics: gamma-Aminobutyric Acid; Pregnenolone; Receptors, GABA-A	2023