Page last updated: 2024-08-20

pregnenolone and finasteride

pregnenolone has been researched along with finasteride in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.11)18.2507
2000's7 (38.89)29.6817
2010's8 (44.44)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Bellavance, E; Luu-The, V; Poirier, D1
Givalois, L; Li, S; Pelletier, G1
Garcia de Yebenes, E; Li, S; Pelletier, G1
Canosa, LF; Ceballos, NR1
Bowen, WD; Martin-Fardon, R; Maurice, T; Romieu, P1
Debonnel, G; Robichaud, M1
Bratoeff, E; Cabeza, M; Heuze, I; Naranjo-Rodríguez, E; Pérez-Ornelas, V; Ramírez, E; Sánchez, M1
Darbra, S; Martín-García, E; Pallarés, M1
Bratoeff, E; Cabeza, M; Heuze, I; Pérez-Ornelas, V; Recillas, S1
Darbra, S; Pallarès, M1
Darbra, S; Modol, L; Pallarès, M; Vallée, M1
Abbiati, F; Caruso, D; Cavaletti, G; Fusco, L; Giatti, S; Melcangi, RC; Romano, S1
Kalinina, TS; Kudriashov, NV; Seredenin, SB; Shimshirt, AA; Voronina, TA1
Banday, AH; Jeelani, S; Shameem, SA1
Abbiati, F; Bini, V; Bortolato, M; Caruso, D; Casti, A; Devoto, P; Frau, R1
Ball, BA; Conley, AJ; Corbin, CJ; Legacki, EL; Scoggin, KE; Stanley, SD1
Carrà, G; Caruso, D; Cavaletti, G; Diviccaro, S; Fusco, ML; Giatti, S; Grimoldi, M; Melcangi, RC; Santi, D; Simoni, M; Spezzano, R; Tabacchi, T1
Caruso, D; Cioffi, L; Diviccaro, S; Falvo, E; Giatti, S; Herian, M; Melcangi, RC1

Other Studies

18 other study(ies) available for pregnenolone and finasteride

ArticleYear
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
Involvement of neurosteroids in the effect of the endogenous benzodiazepine receptor ligand octadecaneuropeptide (ODN) on gonadotropin-releasing hormone gene expression in rat brain.
    Journal of neuroendocrinology, 1997, Volume: 9, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha Reductase Inhibitors; Adrenalectomy; Animals; Diazepam Binding Inhibitor; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Gene Expression; Gonadotropin-Releasing Hormone; Male; Neuropeptides; Orchiectomy; Peptide Fragments; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley

1997
Regulation of proopiomelanocortin gene expression by endogenous ligands of the GABAA receptor complex as evaluated by in situ hybridization in the rat pars intermedia.
    Brain research, 1997, Mar-07, Volume: 750, Issue:1-2

    Topics: Adrenalectomy; Animals; Carrier Proteins; Cerebral Ventricles; Diazepam Binding Inhibitor; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; GABA Agonists; In Situ Hybridization; Injections, Intravenous; Injections, Intraventricular; Male; Neurons; Neuropeptides; Orchiectomy; Peptide Fragments; Pituitary Gland; Pregnenolone; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Transcription, Genetic

1997
Effects of different steroid-biosynthesis inhibitors on the testicular steroidogenesis of the toad Bufo arenarum.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2001, Volume: 171, Issue:6

    Topics: 17-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androgens; Animals; Bufonidae; Cholestenone 5 alpha-Reductase; Cyanoketone; Dehydroepiandrosterone; Enzyme Inhibitors; Finasteride; Male; Oxidoreductases; Pregnenolone; Spironolactone; Steroid 17-alpha-Hydroxylase; Testis; Testosterone

2001
Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, May-01, Volume: 23, Issue:9

    Topics: Animals; Behavior, Animal; Cinnamates; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cyclopropanes; Dehydroepiandrosterone; Disease Susceptibility; Drug Antagonism; Drug Synergism; Enzyme Inhibitors; Finasteride; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pregnenolone; Progesterone; Receptors, sigma; Reward; Sigma-1 Receptor; Steroids

2003
Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids.
    The Journal of endocrinology, 2004, Volume: 182, Issue:1

    Topics: 5-alpha-Dihydroprogesterone; Animals; Anisoles; Antipsychotic Agents; Dehydroepiandrosterone; Dihydrotestosterone; Female; Finasteride; Gender Identity; Gonadal Steroid Hormones; Neurons; Ovariectomy; Pregnenolone; Progesterone; Propylamines; Protein Isoforms; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin; Synaptic Transmission; Time Factors

2004
New 5alpha-reductase inhibitors: in vitro and in vivo effects.
    Steroids, 2005, Volume: 70, Issue:3

    Topics: Androgen Antagonists; Animals; Cholestenone 5 alpha-Reductase; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Finasteride; Humans; In Vitro Techniques; Inhibitory Concentration 50; Male; Models, Chemical; Pregnenolone; Prostate; Solvents

2005
Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration.
    Neuroscience, 2008, Jul-17, Volume: 154, Issue:4

    Topics: Animals; Animals, Newborn; Anxiety; Avoidance Learning; Enzyme Inhibitors; Finasteride; Gonadal Steroid Hormones; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A

2008
In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5alpha-reductase inhibitors.
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 111, Issue:3-5

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Azasteroids; Cricetinae; Cricetulus; Dihydrotestosterone; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Male; Molecular Structure; Nandrolone; Pregnadienes; Pregnenolone; Prostate; Rats; Testosterone; Testosterone Congeners

2008
Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour.
    Behavioural brain research, 2011, Jan-20, Volume: 216, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Adaptation, Physiological; Age Factors; Animals; Animals, Newborn; CA1 Region, Hippocampal; Exploratory Behavior; Finasteride; Male; Microinjections; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Spatial Behavior

2011
Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:8

    Topics: 5-alpha Reductase Inhibitors; Age Factors; Animals; Animals, Newborn; Exploratory Behavior; Finasteride; Hippocampus; Male; Microinjections; Motor Activity; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Rats; Reflex, Startle; Sensory Gating

2013
Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 146

    Topics: 20-alpha-Dihydroprogesterone; Adult; Alopecia; Anxiety Disorders; Case-Control Studies; Depression; Finasteride; Humans; Male; Pregnenolone; Progesterone; Sexual Dysfunctions, Psychological; Steroids

2015
[Neurosteroidogenesis and exploratory responses in rodents].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Animals; Behavior, Animal; Brain; Conditioning, Classical; Exploratory Behavior; Finasteride; Indomethacin; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondrial Proteins; Neurotransmitter Agents; Pregnenolone; Protein Transport; Rats; Rats, Wistar; Stress, Psychological

2014
Steroidal pyrazolines and pyrazoles as potential 5α-reductase inhibitors: synthesis and biological evaluation.
    Steroids, 2014, Volume: 92

    Topics: 5-alpha Reductase Inhibitors; Finasteride; Humans; Male; Pregnenolone; Pyrazoles

2014
Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress.
    Schizophrenia research, 2015, Volume: 168, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Antipsychotic Agents; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Finasteride; Haloperidol; Injections, Intraperitoneal; Male; Nucleus Accumbens; Pregnenolone; Prepulse Inhibition; Random Allocation; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia; Social Isolation; Stress, Psychological

2015
Equine 5α-reductase activity and expression in epididymis.
    The Journal of endocrinology, 2016, Volume: 231, Issue:1

    Topics: 17-Ketosteroids; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstanols; Animals; Dihydrotestosterone; Dutasteride; Epididymis; Female; Finasteride; Horses; Male; Pregnancy; Pregnenolone

2016
Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 171

    Topics: 5-alpha Reductase Inhibitors; Adult; Alopecia; Case-Control Studies; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Monitoring; Erectile Dysfunction; Evoked Potentials, Somatosensory; Finasteride; Humans; Incidence; Italy; Longitudinal Studies; Male; Pregnenolone; Progesterone; Prospective Studies; Psychiatric Status Rating Scales; Pudendal Nerve; Pudendal Neuralgia; Severity of Illness Index; Testosterone; Young Adult

2017
Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats.
    Biomolecules, 2022, 10-26, Volume: 12, Issue:11

    Topics: Animals; Finasteride; Inflammation; Male; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A

2022