pregnenolone has been researched along with dizocilpine maleate in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Kavaliers, M; Kinsella, DM | 1 |
| Fahey, JM; Lindquist, DG; Miller, LG; Pritchard, GA | 1 |
| Itzhak, Y; Norenberg, MD | 1 |
| Cheney, DL; Guidotti, A; Uzunov, D | 1 |
| Kulkarni, SK; Reddy, DS | 1 |
| Cascio, C; De Leo, G; Guarneri, P; Guarneri, R; Piccoli, F; Piccoli, T; Russo, D; Sciuto, V | 1 |
| Maurice, T; Phan, V; Sandillon, F; Urani, A | 1 |
| Nabeshima, T; Nakata, Y; Sasa, M; Yamada, K; Zou, LB | 1 |
| Hayashi, T; Maurice, T; Su, TP | 1 |
| Barbosa, AD; Morato, GS | 1 |
| Guillemain, I; Maurice, T; Phan, VL; Urani, A | 1 |
| Hattori, TA; Kawato, S; Kimoto, T; Takahashi, T; Tanabe, N; Yasumatsu, N | 1 |
| Carta, M; Mameli, M; Partridge, LD; Valenzuela, CF | 1 |
| Partridge, LD; Schiess, AR | 1 |
| Allen, TB; Bradford, DW; Hamer, RM; Kilts, JD; Lieberman, JA; Marx, CE; Naylor, JC; Strauss, JL | 1 |
| Chodounska, H; Chvojkova, M; Holubova, K; Hrcka Krausova, B; Kudova, E; Vales, K; Vyklicky, L; Vyklicky, V | 1 |
1 review(s) available for pregnenolone and dizocilpine maleate
| Article | Year |
|---|---|
Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Drug Evaluation, Preclinical; Humans; Learning; Neurotransmitter Agents; Pregnenolone; Randomized Controlled Trials as Topic; Rats; Schizophrenia | 2011 |
15 other study(ies) available for pregnenolone and dizocilpine maleate
| Article | Year |
|---|---|
Male preference for the odors of estrous female mice is reduced by the neurosteroid pregnenolone sulfate.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Estrus; Female; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Mice; Motivation; Odorants; Pregnenolone; Sexual Behavior, Animal; Smell | 1995 |
Pregnenolone sulfate potentiation of NMDA-mediated increases in intracellular calcium in cultured chick cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Fura-2; Glycine; N-Methylaspartate; Nimodipine; Pregnenolone; Spermine | 1995 |
Attenuation of ammonia toxicity in mice by PK 11195 and pregnenolone sulfate.
Topics: Ammonia; Animals; Clonazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Isoquinolines; Male; Mice; Pregnenolone | 1994 |
Pregnenolone sulfate antagonizes dizocilpine amnesia: role for allopregnanolone.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Brain; Cognition; Dizocilpine Maleate; Dose-Response Relationship, Drug; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Reaction Time | 1995 |
Possible role of nitric oxide in the nootropic and antiamnesic effects of neurosteroids on aging- and dizocilpine-induced learning impairment.
Topics: Aging; Amnesia; Animals; Avoidance Learning; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Enzyme Inhibitors; Learning Disabilities; Male; Maze Learning; Memory; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nootropic Agents; Pregnenolone | 1998 |
Pregnenolone sulfate modulates NMDA receptors, inducing and potentiating acute excitotoxicity in isolated retina.
Topics: Animals; Dizocilpine Maleate; Drug Synergism; L-Lactate Dehydrogenase; Male; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Pregnenolone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina | 1998 |
Differential effect of dehydroepiandrosterone and its steroid precursor pregnenolone against the behavioural deficits in CO-exposed mice.
Topics: Animals; Anisoles; Antipsychotic Agents; Behavior, Animal; Carbon Monoxide Poisoning; Dehydroepiandrosterone; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Learning; Male; Memory; Memory, Short-Term; Mice; Nerve Degeneration; Pregnenolone; Propylamines | 2000 |
Effects of sigma(1) receptor agonist SA4503 and neuroactive steroids on performance in a radial arm maze task in rats.
Topics: Animals; Anisoles; Antipsychotic Agents; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory; Nootropic Agents; Piperazines; Pregnenolone; Progesterone; Propylamines; Psychomotor Performance; Rats; Rats, Wistar; Receptors, sigma; Steroids; Time Factors | 2000 |
Ca(2+) signaling via sigma(1)-receptors: novel regulatory mechanism affecting intracellular Ca(2+) concentration.
Topics: Animals; Bradykinin; Calcium; Calcium Signaling; Dizocilpine Maleate; Morpholines; Nifedipine; Oligonucleotides, Antisense; Pentazocine; Potassium Chloride; Pregnenolone; Rabbits; Receptors, sigma; Tumor Cells, Cultured | 2000 |
Influence of neurosteroids on the development of rapid tolerance to ethanol in mice.
Topics: Animals; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Ethanol; Male; Mice; Motor Activity; Muscimol; Pregnenolone; Steroids | 2001 |
Differential involvement of the sigma(1) (sigma(1)) receptor in the anti-amnesic effect of neuroactive steroids, as demonstrated using an in vivo antisense strategy in the mouse.
Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Binding Sites; Blotting, Western; Brain; Cerebral Cortex; Dehydroepiandrosterone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Learning Disabilities; Male; Maze Learning; Memory; Mice; Morpholines; Oligonucleotides, Antisense; Phenazocine; Pregnenolone; Receptors, sigma; Sigma-1 Receptor | 2001 |
Corticosterone acutely prolonged N-methyl-d-aspartate receptor-mediated Ca2+ elevation in cultured rat hippocampal neurons.
Topics: Androstanols; Animals; Calcium; Calcium Signaling; Cells, Cultured; Corticosterone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Hippocampus; Hormone Antagonists; Membrane Potentials; Mifepristone; Mitochondria; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate | 2002 |
Neurosteroid-induced plasticity of immature synapses via retrograde modulation of presynaptic NMDA receptors.
Topics: Age Factors; Animals; Animals, Newborn; Antibodies; Calcium; Calcium Channel Blockers; Chelating Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Neuronal Plasticity; Patch-Clamp Techniques; Piperidines; Pregnenolone; Presynaptic Terminals; Quinolinic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors | 2005 |
Pregnenolone sulfate acts through a G-protein-coupled sigma1-like receptor to enhance short term facilitation in adult hippocampal neurons.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GTP-Binding Protein alpha Subunits, Gi-Go; Hippocampus; In Vitro Techniques; Male; Morpholines; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Piperazines; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sigma-1 Receptor; Synapses; Synaptic Transmission; Time Factors | 2005 |
Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dizocilpine Maleate; Elevated Plus Maze Test; HEK293 Cells; Humans; Male; Pregnenolone; Rats, Long-Evans; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Steroids | 2021 |