pregnenolone has been researched along with diazepam in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caron, G; Ermondi, G | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Costa, E; Guarneri, P; Guidotti, A; Kreuger, KE; Papadopoulos, V | 1 |
| Besman, MJ; Hall, PF; Kawamura, M; Lee, TD; Shively, JE; Yanagibashi, K | 1 |
| Hayashida, K; Kawamura, M; Matsui, T; Nakamichi, N; Ohno, Y; Takamura, M; Tou, S; Yamada, K; Yanagibashi, K | 1 |
| Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J | 1 |
| Bender, AS; Norenberg, MD | 1 |
| Akhondzadeh, S; Stone, TW | 1 |
| Bertram, EH; Kapur, J; Mtchedlishvili, Z | 1 |
| Altobelli, D; Cannizzaro, C; D'Amico, M; Martire, M; Preziosi, P | 1 |
| Meieran, SE; Reus, VI; Shafton, R; Webster, R; Wolkowitz, OM | 1 |
| Ahmed, RS; Mahajan, P; Mediratta, PK; Sahaya, K; Sharma, KK | 1 |
| Bauer, A; Haen, E; Hallof-Buestrich, H; Kreutz, M; Melchner, D; Milenkovic, VM; Nothdurfter, C; Rupprecht, R; Sarubin, N; Stoertebecker, P; Wetzel, CH; Wolf, L | 1 |
| Chen, SL; Liu, XG; Wei, XH; Zang, Y; Zheng, WH | 1 |
1 trial(s) available for pregnenolone and diazepam
| Article | Year |
|---|---|
Chronic pregnenolone effects in normal humans: attenuation of benzodiazepine-induced sedation.
Topics: Adult; Affect; Aged; Cross-Over Studies; Diazepam; Double-Blind Method; Female; GABA Modulators; Humans; Hypnotics and Sedatives; Male; Memory; Middle Aged; Pilot Projects; Pregnenolone; Reference Values; Sleep; Statistics, Nonparametric | 2004 |
13 other study(ies) available for pregnenolone and diazepam
| Article | Year |
|---|---|
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor.
Topics: Animals; Cholesterol Side-Chain Cleavage Enzyme; Diazepam; Diazepam Binding Inhibitor; Glioma; In Vitro Techniques; Ligands; Mitochondria; Neuropeptides; Pregnenolone; Rats; Receptors, Cell Surface; Tumor Cells, Cultured | 1992 |
Identification of des-(Gly-Ile)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor.
Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Cattle; Cholesterol; Chromatography, High Pressure Liquid; Diazepam; Kinetics; Mass Spectrometry; Mitochondria; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Fragments; Pregnenolone; Receptors, GABA-A; Trypsin; Zona Fasciculata | 1989 |
Peripheral-type benzodiazepine receptors are involved in the regulation of cholesterol side chain cleavage in adrenocortical mitochondria.
Topics: Adrenal Cortex; Animals; Benzodiazepines; Calcium; Cattle; Cholesterol; Diazepam; Digitonin; Mitochondria; Pregnenolone; Receptors, GABA-A; Steroids | 1989 |
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem | 1998 |
Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes.
Topics: Ammonia; Astrocytes; Atrial Natriuretic Factor; Benzodiazepines; Benzodiazepinones; Brain Edema; Cell Size; Clonazepam; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Diazepam; Diazepam Binding Inhibitor; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoquinolines; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Pregnanolone; Pregnenolone; Protoporphyrins; Receptors, GABA-A; Steroids; Up-Regulation | 1998 |
Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate.
Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Synergism; Hippocampus; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Time Factors | 1998 |
Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Diazepam; Electric Conductivity; Epilepsy, Temporal Lobe; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Pregnanolone; Pregnenolone; Pyridines; Rats; Receptors, GABA-A; Zinc; Zolpidem | 2001 |
Neurosteroid modulation of the presynaptic NMDA receptors regulating hippocampal noradrenaline release in normal rats and those exposed prenatally to diazepam.
Topics: Animals; Diazepam; Female; Glycine; Hippocampus; Male; Norepinephrine; Pregnancy; Pregnenolone; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 2003 |
Reversal of lindane-induced impairment of step-down passive avoidance and oxidative stress by neurosteroids in rats.
Topics: Administration, Oral; Animals; Avoidance Learning; Behavior, Animal; Brain Chemistry; Diazepam; Drug Antagonism; Drug Therapy, Combination; Hexachlorocyclohexane; Insecticides; Male; Malondialdehyde; Maze Learning; Oxidative Stress; Pregnenolone; Progesterone; Rats; Rats, Wistar; Recovery of Function | 2007 |
Enhancing neurosteroid synthesis--relationship to the pharmacology of translocator protein (18 kDa) (TSPO) ligands and benzodiazepines.
Topics: Animals; Cells, Cultured; Diazepam; Dose-Response Relationship, Drug; Mice; Neurotransmitter Agents; Oxazines; Pregnenolone; Purines; Radioligand Assay; Rats; Receptors, GABA | 2015 |
Inhibition of Neuropathic Pain by a Single Intraperitoneal Injection of Diazepam in the Rat: Possible Role of Neurosteroids.
Topics: Animals; Benzodiazepinones; Carrier Proteins; Diazepam; Flumazenil; Injections, Intraperitoneal; Interleukin-1beta; Male; Neuralgia; Neurotransmitter Agents; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2016 |