pregnenolone has been researched along with desoxycorticosterone in 265 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 185 (69.81) | 18.7374 |
| 1990's | 33 (12.45) | 18.2507 |
| 2000's | 33 (12.45) | 29.6817 |
| 2010's | 10 (3.77) | 24.3611 |
| 2020's | 4 (1.51) | 2.80 |
| Authors | Studies |
|---|---|
| Kollman, PA; Lee, DL; Marsh, FJ; Wolff, ME | 1 |
| Dunn, WJ; Grigoras, S; Koehler, MG | 1 |
| Chapman, D; Jain, AN; Koile, K | 1 |
| Good, AC; Peterson, SJ; Richards, WG | 1 |
| Good, AC; Richards, WG; So, SS | 1 |
| Platt, DE; Silverman, BD | 1 |
| Crippen, GM | 1 |
| Karplus, M; So, SS | 1 |
| Hamprecht, FA; Kubinyi, H; Mietzner, T | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Clementi, S; Cruciani, G; McLay, I; Pastor, M; Pickett, S | 1 |
| Baumann, K; Stiefl, N | 1 |
| Gynther, J; Honkakoski, P; Jyrkkärinne, J; Mäkinen, J; Poso, A; Savolainen, H | 1 |
| Higashiura, K; Kotani, T | 1 |
| Caron, G; Ermondi, G | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N | 1 |
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Simpson, ER; Williams-Smith, DL | 2 |
| Bedigian, E; Haksar, A; Maudsley, DV; Péron, FG | 1 |
| Blaizot, J; Blaizot, S; Poul, JM | 1 |
| Vinson, GP; Whitehouse, BJ | 8 |
| Hall, BK; Kalliecharan, R | 1 |
| Bell, JB; Hyatt, PJ; McDougall, JG; Tait, JF; Tait, SA; Williams, BC | 1 |
| Bell, JB; Gould, RP; Hyatt, PJ; Tait, JF; Tait, SA | 1 |
| Biglieri, EG; Honour, JW; Shackleton, CH; Tourniaire, J | 1 |
| Finkelstein, M; Shaefer, JM | 1 |
| Island, DP; Liddle, GW; McKenna, TJ; Nicholson, WE | 2 |
| Headon, DR; Hsiao, J; Ungar, F | 1 |
| Blaha, GC; Leavitt, WW | 1 |
| Arai, K; Okinaga, S; Sano, Y; Sekiba, K; Shibusawa, H; Yanaihara, T; Yoshida, N | 1 |
| Duggan, RT; Lofts, B | 1 |
| Haschek, H; Herkner, K; Jörg, J; Waldhäusl, W | 1 |
| Colombo, L; Yaron, Z | 1 |
| Bergon, L; Brownie, AC | 1 |
| Cunningham, FJ; Etches, RJ | 1 |
| Bowers, BJ; Wehner, JM | 1 |
| Ambrosio, C; Barbaccia, ML; Massotti, M; Roscetti, G; Trabucchi, M | 1 |
| Müller, J | 2 |
| Hurwitz, S; Pines, M; Rosenberg, J | 1 |
| Gautier, T; Imperato-McGinley, J; Peterson, RE; Shackleton, C | 1 |
| Ghersi-Egea, JF; Minn, A; Siest, G; Walther, B | 1 |
| Makino, K; Miura, K; Ojima, M; Okuyama, M; Sasano, N; Yasuda, K | 1 |
| Ikeda, M; Katagiri, M; Koshida, H; Miyamori, I; Nagai, K; Suhara, K; Takeda, R | 1 |
| Takeda, R | 1 |
| Birmingham, MK; De Nicola, AF; Holzbauer, M; Oliver, JT | 1 |
| Hamilton, MA; McCune, RW; Roberts, S | 1 |
| Carballeira, A; Cheng, SC; Fishman, LM | 2 |
| Alonso, C; McIntosh, EN; Mitani, F; Salhanick, HA; Uzgiris, VI | 1 |
| Schuetz, AW | 2 |
| Giroud, CJ; Klein, GP | 1 |
| Dao, TL; Libby, PR | 1 |
| Boström, H; Brömster, D; Nordenstam, H; Wengle, B | 1 |
| Anderson, JM; McCormick, MH; Neville, AM; Webb, JL | 1 |
| Emerson, K; Rose, LI; Villee, DB; Williams, GH | 1 |
| Eriksson, H; Gustafsson, JA | 1 |
| Lucis, OJ; Lucis, R | 1 |
| Gupta, C; Karavolas, HJ | 1 |
| Allen, SH; Wiener, M | 1 |
| Brough, AJ; Camacho, AM; Kowarski, A; Migeon, CJ | 1 |
| Kittinger, GW | 1 |
| Bryson, MJ; Sweat, ML | 2 |
| Island, DP; Kloppenborg, PW; Liddle, GW; Michelakis, AM; Nicholson, WE | 1 |
| Camacho, AM; Hagen, AA; Trouy, RL; Wilroy, RS | 1 |
| Johnston, GG; Krisle, JR; Troop, RC | 1 |
| Fevold, HR | 1 |
| Dominguez, OV; Huseby, RA | 1 |
| Horie, S; Mitani, F | 2 |
| Chan, ST; Edwards, BR | 1 |
| Beamer, NB; Kittinger, GW | 1 |
| Dorfman, RI; Forchielli, E; Lommer, D | 2 |
| Kharma, KM; Mishell, DR; Nakamura, RM; Stone, S; Thorneycroft, IH | 1 |
| Llamas, R | 1 |
| Boyd, GS; Brownie, AC; Jefcoate, CR; Simpson, ER | 1 |
| Ando, N; Horie, S | 2 |
| Anderson, AB; Griffiths, K; Pierrepoint, CG; Turnbull, AC | 1 |
| Antic, B; Ducharme, JR; Limal, JM; Sandor, T | 1 |
| Cooper, DY; Levin, SS; Rosenthal, O; Schleyer, H | 1 |
| Sharma, RK | 1 |
| Krum, AA; Slaga, TJ | 1 |
| Nakamura, T; Tanabe, Y | 1 |
| Diedrichsen, G; Lommer, D; Lommer, I | 1 |
| Cheng, SC; Harding, BW | 1 |
| Brush, JS; Sharma, RK; Sutliff, LS | 1 |
| Brown, RD; Hardman, JG; Island, DP; Liddle, GW; Nicholson, WE; Peytremann, A | 1 |
| Diedrichsen, G; Herzog, P; Lommer, D; Sinterhauf, K | 2 |
| Bell, JJ; Cheng, SC; Harding, BW | 1 |
| McCarthy, JL; Rietz, CW; Wesson, LK | 1 |
| Guerra, F; McCarthy, JL; Péron, FG | 1 |
| Ertel, RJ; Ungar, F | 1 |
| Caldwell, BV; McCarthy, JL; Péron, FG | 1 |
| Hotz, D; Maschwitz, U; Schildknecht, H | 1 |
| Simpson, TH; Wright, RS | 1 |
| Selye, H | 3 |
| Hall, PF; Young, DG | 1 |
| Carballeira, A; Mehdi, AZ | 1 |
| Rembiesa, R; Warchol, A | 1 |
| Belvedere, P; Colombo, L; Daniels, E; Yaron, Z | 1 |
| Kourounakis, P; Selye, H; Szabo, S | 1 |
| Birmingham, MK; de Nicola, A; Godden, U; Holzbauer, M; Traikov, H | 1 |
| Jeffries, CD; Wilkins, J | 1 |
| Chan, SW; Phillips, JG | 2 |
| Dahl, V; De Nicola, AF; Kaplan, S | 1 |
| Brush, JS; Sharma, RK | 1 |
| Birmingham, MK; Birmingham, ML; De Nicola, AF; Godden, U; Holzbauer, M; Oliver, JT; Sharman, DF; Traikov, H | 1 |
| Guériguian, JL; Pearlman, WH; Sawyer, ME | 1 |
| Fevold, HR; Pfeiffer, EW; Rice, JS | 1 |
| Frydman, B; Frydman, RB; Tomaro, ML | 1 |
| Lea, OA | 1 |
| Boyd, GS; Jefcoate, CR; Simpson, ER | 1 |
| Villee, DB | 1 |
| Cohen, RB; Kliman, B; Neeman, J; Weinstein, RL | 1 |
| Birmingham, MK; Lantos, CP; Traikov, H | 1 |
| Hurst, L; Jayle, MF; Lacassagne, A | 1 |
| Birmingham, MK; De Nicola, AF | 1 |
| Gay, VL; Midgley, AR; Niswender, GD; Reichet, LE | 1 |
| Kliman, B; Weinstein, RL | 1 |
| Bricaire, H; Corvol, P; Laudat, P; Legrand, JC; Lemmer, M; Luton, JP; Turpin, G | 1 |
| Idler, DR; Sangalang, GB; Truscott, B | 1 |
| DeVilla, GO; Flickinger, G; Mikhail, G; Roberts, K; Wiest, WG | 1 |
| Meyer, RK; Ying, SY | 1 |
| Holzbauer, M | 1 |
| Lieberman, S; Lippman, V | 1 |
| Oakey, RE; Shahwan, MM; Stitch, SR | 1 |
| Jelinek, J; Krajny, M; Selye, H | 1 |
| Axelrod, LR; Goldzieher, JW; Woodhead, DM | 1 |
| Birmingham, MK; De Nicola, AF; Palmer, JD; Ruddick, DW; Traikov, H | 1 |
| Chadha, MS; Joshi, NK; Mamdapur, VR; Sipahimalani, AT | 1 |
| Anderson, AB; Griffiths, K; Jones, T; Pierrepoint, CG; Turnbull, AC | 1 |
| Hall, PF; Holroyd, JD; Young, DG | 1 |
| Aakvaag, A | 1 |
| Idler, DR; Sangalang, GB | 1 |
| Eriksson, H | 1 |
| Endo, H; Sugimoto, M | 1 |
| Eik-Nes, KB; Tcholakian, RK | 1 |
| Hall, PF; Isaka, S | 1 |
| Inano, H; Machino, A; Tamaoki, BI; Tsubura, Y | 1 |
| Blank, IH; Brauner, GJ; MacFarlane, DJ; Scheuplein, RJ | 1 |
| Arai, R; Tajima, H; Tamaoki, BI | 1 |
| Chan, SW; Phillips, JG; Vinson, GP | 1 |
| Bishop, CF; Melnykovych, G | 1 |
| Burstein, SH; Péron, FG; Williamson, E | 1 |
| Driscoll, SG; Villee, DB | 1 |
| Dorfman, RI; Gabrilove, JL; Raman, PB; Sharma, DC | 1 |
| Creange, FE; Roberts, S; Young, PL | 1 |
| Vinson, GP | 2 |
| Ebadi, M; McCoy, E | 1 |
| Diab, IM; Gomoll, AW | 1 |
| McGuire, WL; Middleton, PA; O'Malley, BW | 1 |
| Moscona, AA; Piddington, R | 1 |
| Fukuchi, S; Ojima, M; Saito, M | 1 |
| Thorburn, GD; Willcox, DL | 1 |
| Casey, ML; Guerami, A; MacDonald, PC; Winkel, CA | 1 |
| Greenfield, NJ; Lieberman, S; Wolfson, A | 1 |
| Eberle, C; Locher, R; Lüscher, T; Thun, R; Vetter, H; Vetter, W; Walter, H | 1 |
| Chanderbhan, R; Noland, BJ; Scallen, TJ; Vahouny, GV | 1 |
| Callard, IP; Giannoukos, G | 1 |
| Barbaccia, ML; Biggio, G; Concas, A; Cuccheddu, T; Roscetti, G; Trabucchi, M | 1 |
| Hanukoglu, I; Rapoport, R; Sklan, D | 1 |
| De Villiers, EP; Swart, AC; Swart, P; Todres, PC; van der Merwe, KJ | 1 |
| Ashwell, JD; Papadopoulos, V; Vacchio, MS | 1 |
| Jefcoate, CR; McNamara, BC; Yamazaki, T | 1 |
| Abayasekara, DR; Purdy, SJ; Whitehouse, BJ | 1 |
| Andreis, P; Malendowicz, LK; Neri, G; Nussdorfer, GG | 1 |
| Franco-Saenz, R; Gupta, P; Mulrow, PJ | 1 |
| Devaud, LL; Morrow, AL; Paul, SM; Purdy, RH | 1 |
| Matsumoto, K; Ojima, K; Watanabe, H | 1 |
| Acosta-Burruel, M; Goodnough, DB; Hawkinson, JE; Kimbrough, CL; Wood, PL | 1 |
| Krueger, KE; Vicini, S; Wang, JF; Zhu, WJ | 1 |
| Barbaccia, ML; Biggio, G; Concas, A; Mostallino, MC; Perra, C; Purdy, RH; Roscetti, G; Trabucchi, M | 1 |
| Ichikawa, Y; Ohnishi, T | 1 |
| Matsumoto, K; Nguyen, TT; Watanabe, H; Yamasaki, K | 1 |
| Chapell, R; Leidenheimer, NJ | 1 |
| Bender, AS; Norenberg, MD | 1 |
| Holsboer, F; Rupprecht, R | 1 |
| Bidziński, A; Członkowska, AI; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H | 1 |
| Chen, JJ; Chiao, YC; Fang, VS; Ho, LT; Kau, MM; Lin, H; Lo, MJ; Shum, AY; Tsai, SC; Wang, PS; Wang, SW; Yeh, JY | 1 |
| Biggio, G; Carotti, A; Franco, M; Latrofa, A; Liso, G; Ricciardi, L; Sanna, E; Serra, M; Trapani, G | 1 |
| Chang, LL; Chen, JJ; Chiao, YC; Huang, WJ; Kan, SF; Kau, MM; Lin, H; Lo, MJ; Tsai, SC; Wang, JL; Wang, PS; Wun, WS; Yeh, JY | 1 |
| Biggio, G; Littera, M; Papi, G; Pisu, MG; Purdy, RH; Sanna, E; Serra, M; Tuveri, F; Usala, L | 1 |
| Brown, JW; Fishman, LM | 1 |
| Bidziński, A; Członkowska, AI; Krzaścik, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J | 1 |
| Bhattachryya, SP; Debnath, S; Mukherjee, D | 1 |
| Barbosa, AD; Morato, GS | 2 |
| Homanics, GE; Huguenard, JR; Huntsman, MM; Mihalek, RM; Porcello, DM | 1 |
| Bellodi, L; Biggio, G; Bogdanovich-Djukic, V; Brambilla, F; Perna, G; Pisu, MG; Purdy, RH; Serra, M | 1 |
| Macchi, C; Malendowicz, LK; Nussdorfer, GG; Spinazzi, R; Tortorella, C; Trejter, M | 1 |
| MENDELL, HE; MOYER, JH; SKELTON, JM | 1 |
| MELI, A | 1 |
| AMANTE, S; MANCINI, M | 1 |
| FUENZALIDA, F; LIPSCHUTZ, A | 1 |
| BERGEN, JR; HOAGLAND, H; HUNT, C; SLOCOMBE, A | 1 |
| GIULIANO, V; RUBINO, GF | 1 |
| BROWN, EA; KAGAWA, CM | 1 |
| BENNETT, RD; HEFTMANN, E | 1 |
| MATSUDA, N; YAMAMOTO, TO | 1 |
| GOTTFRIED, H; SIMPSON, TH; WRIGHT, RS | 1 |
| ACEVEDO, HF; AXELROD, LR; ISHIKAWA, E; TAKAKI, F | 1 |
| LAMOUREUX, J; LANTHIER, A; SANDOR, T | 1 |
| BAULIEU, EE; LEBEAU, MC | 1 |
| SAWAZAKI, C | 1 |
| ADAMS, JB | 1 |
| WENGLE, B | 1 |
| PERON, FG | 1 |
| RENFREW, J; SIMPSON, TH; WRIGHT, RS | 1 |
| HUNT, SV; SIMPSON, TH; WRIGHT, RS | 1 |
| LORING, JM; VILLEE, CA | 1 |
| DORFMAN, RI; GABRILOVE, JL; RAHEJA, MC; SHARMA, DC | 1 |
| HALL, JC; LILJEROOT, BS | 1 |
| Chang, LL; Ho, LL; Wang, PS; Wun, WS | 1 |
| Alomary, AA; Fitzgerald, RL; Koob, GF; O'Dell, LE; Purdy, RH; Vallée, M | 1 |
| AMIRA, A; BORASI, M; CAVALLERO, C; SALA, G | 1 |
| CHARVAT, J; CHYTIL, F | 1 |
| ANGRIST, AA; KATONAH, F; PARMER, LG | 1 |
| BUSSI, L; DE MICHELI, E; SALA, G | 1 |
| MALAGUTI, G; VACCARI, F | 1 |
| Biggio, G; Brambilla, F; Gerra, G; Pisu, MG; Purdy, RH; Serra, M; Zaimovich, A | 1 |
| Prevoo, D; Smith, C; Swart, AC; Swart, P | 1 |
| Ahboucha, S; Butterworth, RF; Mamer, O; Pomier-Layrargues, G | 1 |
| Grant, KA; Morrow, AL; Porcu, P; Rogers, LS | 1 |
| Bäckström, T; Johansson, IM; Lindblad, C; Rahman, M; Wang, MD | 1 |
| Bradford, DW; Butterfield, MI; Grobin, AC; Khisti, RT; Lieberman, JA; Madison, RD; Marx, CE; Massing, MW; Morrow, AL; Shampine, LJ; Trost, WT | 1 |
| Chang, LL; Chiang, W; Hsia, SM; Hung, CT; Wang, PS; Wun, AW | 1 |
| Hamann, M; Richter, A; Richter, F | 1 |
| Adinoff, B; Leslie Morrow, A; O'Buckley, TK; Porcu, P | 1 |
| Biggio, G; Concas, A; Marotto, MF; Marra, C; Marrosu, F; Melis, GB; Orrù, M; Paoletti, AM; Sogliano, C; Tuveri, A; Zedda, P | 1 |
| Chambers, T; Donn, R; Grundy, S; Loudon, AS; McMaster, A; Meng, QJ; Ray, DW | 1 |
| Ahboucha, S; Baker, GB; Butterworth, RF; Chatauret, N; Jiang, W; Mamer, O | 1 |
| Chao, HL; Wang, PS; Wang, SW; Yu, PL | 1 |
| Alward, SE; de Wit, H; Grant, KA; Leslie Morrow, A; O'Buckley, TK; Porcu, P; Song, SC | 1 |
| Baker, C; Bamber, BA; Sturt, BL | 1 |
| Balashov, AM | 1 |
| Alfred Wun, WS; Chang, LL; Wang, PS | 1 |
| Arlt, W; de Herder, WW; de Jong, FH; Feelders, RA; Hofland, J; Hofland, LJ; Steenbergen, J; Taylor, AE; van der Pas, R; van Koetsveld, PM | 1 |
| Bernhardt, R; Gerber, A; Hannemann, F; Mosa, A; Neunzig, J; Pilak, P; Zapp, J | 1 |
| Caley, A; Gielen, MC; Harvey, RJ; Smart, TG; Wilkins, ME | 1 |
| Bando, K; Fujii, Y; Kouchi, M; Matsumoto, I; Miyawaki, I; Tochitani, T; Yamada, T; Yamashita, A | 1 |
| Fujii, Y; Kouchi, M; Matsumoto, I; Miyawaki, I; Tochitani, T; Yamashita, A | 1 |
| Aleman, M; Chigerwe, M; Madigan, JE; McCue, PM | 1 |
| Deligiannidis, KM; Dubuke, ML; Kroll-Desrosiers, AR; Shaffer, SA; Tan, Y | 1 |
| Hou, C; Huang, F; Jin, Z; Ye, A; Zhou, F; Zhu, L | 1 |
| Bongrani, A; Dupont, J; Froment, P; Guerif, F; Mellouk, N; Plotton, I; Ramé, C | 1 |
| Akıncı, E; Bal, C; Erel, Ö; Eser, F; Güner, R; Hasanoglu, İ; Kalem, AK; Kayaaslan, B; Sezer, S; Yılmaz, G | 1 |
12 review(s) available for pregnenolone and desoxycorticosterone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Inborn errors of steroid biosynthesis.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Cattle; Cholesterol; Corticosterone; Cortodoxone; Desoxycorticosterone; Humans; Hydrocortisone; Hydroxylation; Hydroxyprogesterones; Pregnenolone; Progesterone; Rats; Steroid Hydroxylases | 1979 |
Aldosterone biosynthesis in bovine, rat and human adrenal: commonalities and challenges.
Topics: Adrenal Cortex; Aldosterone; Animals; Cattle; Corticosterone; Desoxycorticosterone; Humans; Pregnenolone; Rats; Steroid 11-beta-Hydroxylase | 1991 |
[Review on internal medicine, 1984. Electrolyte disturbance. II-2. Mineralocorticoids and potassium imbalance].
Topics: Adult; Aldosterone; Bartter Syndrome; Chlorides; Desoxycorticosterone; Female; Humans; Hypokalemia; Male; Potassium; Pregnenolone | 1985 |
[Mechanisms of action of adrenocorticotrophic hormone].
Topics: Adrenocorticotropic Hormone; Animals; Calcium; Corticosterone; Cyclic AMP; Desoxycorticosterone; Glucocorticoids; Mitochondria; Pituitary-Adrenal System; Potassium; Pregnenolone; Progesterone; Protein Biosynthesis; Rats; Swine | 1971 |
Protection by catatoxic steroids against cyclophosphamide-induced organ lesions.
Topics: Adrenal Glands; Animals; Body Weight; Bone Marrow; Cyclophosphamide; Desoxycorticosterone; Enzyme Induction; Estradiol; Ethylestrenol; Female; Ketones; Microsomes, Liver; Mortality; Oxandrolone; Phenobarbital; Prednisolone; Pregnancy; Pregnanediones; Pregnanes; Pregnenolone; Progesterone; Rats; Spironolactone; Thyroxine; Triamcinolone | 1970 |
Effects of progesterone on enzyme activity of adrenals in organ culture.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Corticosterone; Culture Techniques; Desoxycorticosterone; Female; Fetus; Glucose; Glycogen; Humans; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Hyperplasia; Isomerases; Lactates; Mice; Pregnancy; Pregnenolone; Progesterone; Steroids; Tritium | 1966 |
Use of antibodies for characterization of gonadotropins and steroids.
Topics: Animals; Antibodies; Antibody Formation; Antibody Specificity; Antigen-Antibody Complex; Antigen-Antibody Reactions; Cattle; Chorionic Gonadotropin; Chromatography, Gel; Corticosterone; Desoxycorticosterone; Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropins; Gonadotropins, Pituitary; Humans; Immune Sera; Immunochemistry; Immunodiffusion; Iodine Isotopes; Luteinizing Hormone; Models, Structural; Pregnenolone; Progesterone; Prolactin; Rabbits; Radioimmunoassay; Species Specificity; Testosterone; Thyrotropin | 1971 |
A heuristic proposal for understanding steroidogenic processes.
Topics: Aldosterone; Animals; Aromatase; Cholesterol; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Estrogens; Humans; Hydrocortisone; Hydroxylation; Isoenzymes; Microsomes; Mitochondria; Mixed Function Oxygenases; Models, Chemical; Pregnenolone; Steroid 11-beta-Hydroxylase; Steroid 21-Hydroxylase; Steroid Hydroxylases; Steroids | 1984 |
Neuroactive steroid modulators of the stress response.
Topics: Adrenalectomy; Alcoholism; Animals; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Estrus; Female; Flunitrazepam; Hypothalamo-Hypophyseal System; Male; Menstruation; Pregnancy; Pregnanolone; Pregnenolone; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Stress, Physiological | 1995 |
Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives.
Topics: Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Humans; Neuroprotective Agents; Neurosecretory Systems; Pregnanolone; Pregnenolone; Progesterone; Steroids | 1999 |
[Neurosteroids and addictive pathology].
Topics: Adrenal Cortex Hormones; Androstenedione; Behavior, Addictive; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Humans; Narcotics; Pregnenolone; Substance-Related Disorders | 2010 |
253 other study(ies) available for pregnenolone and desoxycorticosterone
| Article | Year |
|---|---|
Quantitative relationships between steroid structure and binding to putative progesterone receptors.
Topics: Androstenes; Animals; Guinea Pigs; Humans; Hydroxyprogesterones; Protein Binding; Rabbits; Receptors, Progesterone; Sheep; Steroids; Structure-Activity Relationship | 1977 |
The role of solvent-accessible surface area in determining partition coefficients.
Topics: Diffusion; Solubility; Solvents; Structure-Activity Relationship | 1987 |
Compass: predicting biological activities from molecular surface properties. Performance comparisons on a steroid benchmark.
Topics: Algorithms; Models, Molecular; Models, Statistical; Molecular Conformation; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Surface Properties; Transcortin | 1994 |
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship | 1993 |
Structure-activity relationships from molecular similarity matrices.
Topics: Computer Simulation; Electrochemistry; Models, Molecular; Molecular Structure; Neural Networks, Computer; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Transcortin | 1993 |
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone | 1996 |
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data.
Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin | 1997 |
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 1. Method and validations.
Topics: Algorithms; Models, Chemical; Molecular Structure; Neural Networks, Computer; Protein Binding; Static Electricity; Steroids; Structure-Activity Relationship; Transcortin | 1997 |
Three-dimensional quantitative similarity-activity relationships (3D QSiAR) from SEAL similarity matrices.
Topics: Drug Design; Least-Squares Analysis; Molecular Conformation; Steroids; Structure-Activity Relationship; Transcortin | 1998 |
GRid-INdependent descriptors (GRIND): a novel class of alignment-independent three-dimensional molecular descriptors.
Topics: Butyrophenones; Enzyme Inhibitors; Glucose; Models, Molecular; Phosphorylases; Protein Binding; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Software; Steroids; Transcortin | 2000 |
Mapping property distributions of molecular surfaces: algorithm and evaluation of a novel 3D quantitative structure-activity relationship technique.
Topics: Acetates; Alcohols; Algorithms; Cholinergic Agents; Hydrocarbons, Acyclic; Hydrocarbons, Aromatic; Ketones; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Receptor, Muscarinic M2; Receptors, Muscarinic; Steroids; Transcortin | 2003 |
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor.
Topics: Animals; Cell Line; Constitutive Androstane Receptor; Histone Acetyltransferases; Humans; Mice; Models, Molecular; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Protein Structure, Secondary; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Repressor Proteins; Steroids; Transcription Factors; Two-Hybrid System Techniques; Yeasts | 2003 |
Comparative molecular active site analysis (CoMASA). 1. An approach to rapid evaluation of 3D QSAR.
Topics: Binding Sites; Cluster Analysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship; Steroids | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids | 2008 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
Electron paramagnetic resonance spectra of mitochondrial and microsomal cytochrome P-450 from the rat adrenal.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Calcium; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Female; Hydrogen-Ion Concentration; Isocitrates; Metyrapone; Microsomes; Mitochondria; Pregnenolone; Rats; Succinates | 1976 |
Effect of calcium(ion) uptake by rat adrenal mitochondria on pregnenolone formation and spectral properties of cytochrome P-450.
Topics: Adrenal Glands; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Female; Kinetics; Mitochondria; Pregnenolone; Protein Binding; Rats; Receptors, Cell Surface; Spectrophotometry; Succinates; Valinomycin | 1975 |
Lanthanum: inhibition of ACTH-stimulated cyclic AMP and corticosterone synthesis in isolated rat adrenocortical cells.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium; Corticosterone; Cyclic AMP; Desoxycorticosterone; Dose-Response Relationship, Drug; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Lanthanum; Microscopy, Electron; Models, Biological; Pregnenolone; Rats | 1976 |
[Adrenal cortex and avitaminosis A: II. Complementary in vivo and in vitro studies on inhibition of corticoidogenesis in moderate deficiency in the rat. III. In vivo criterion for activity: glycemic response to ACTH].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Desoxycorticosterone; Hydroxysteroid Dehydrogenases; Hypoglycemia; Liver Glycogen; Male; Pregnenolone; Progesterone; Rats; Stress, Physiological; Vitamin A Deficiency | 1975 |
Formation of corticosteroids in vitro by interrenal tissue from the teleost fish, Coregonus clupeoides.
Topics: Acetates; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Cortisone; Cortodoxone; Desoxycorticosterone; Fishes; Hormones; Hydrocortisone; Hydroxycorticosteroids; In Vitro Techniques; Interrenal Gland; Pituitary Hormones; Pregnenolone | 1975 |
The in vitro biosynthesis of steroids from pregnenolone and cholesterol and the effects of bovine ACTH on corticoid production by adrenal glands of embryonic chicks.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Chick Embryo; Cholesterol; Corticosterone; Cortisone; Desoxycorticosterone; Hydrocortisone; In Vitro Techniques; Pregnenolone; Progesterone | 1977 |
Properties of dispersed cells from rat adrenals.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Carbon Radioisotopes; Corticosterone; Desoxycorticosterone; Female; In Vitro Techniques; Microbial Collagenase; Pregnenolone; Rats | 1979 |
Properties of rat adrenal zona reticularis cells: production and stimulation of certain steroids.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Androstenedione; Animals; Corticosterone; Desoxycorticosterone; Female; In Vitro Techniques; Pregnenolone; Rats; Stimulation, Chemical | 1979 |
Urinary steroid excretion in 17 alpha-hydroxylase deficiency.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Corticosterone; Desoxycorticosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Middle Aged; Models, Biological; Pregnenolone; Progesterone; Steroid Hydroxylases; Steroids | 1978 |
Dopamine inhibits angiotensin-stimulated aldosterone biosynthesis in bovine adrenal cells.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Cattle; Desoxycorticosterone; Dopamine; In Vitro Techniques; Osmolar Concentration; Pregnenolone; Time Factors | 1979 |
The intracellular localization of adrenal 3beta-hydroxysteroid dehydrogenase/delta5-isomerase by density gradient perturbation.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Animals; Cattle; Centrifugation, Density Gradient; Desoxycorticosterone; Endoplasmic Reticulum; Microsomes; Mitochondria; Pregnenolone; Progesterone; Progesterone Reductase; Succinate Dehydrogenase; Tetrazolium Salts | 1978 |
Deciduomal responses in the uteri of ovariectomized golden hamsters, comparing progesterone and three closely related steroids applied in utero.
Topics: 20-alpha-Dihydroprogesterone; Animals; Castration; Cricetinae; Decidua; Desoxycorticosterone; Drug Implants; Female; Mesocricetus; Pregnenolone; Progesterone; Uterus | 1978 |
Biosynthetic pathways for corticoids and androgen formation in human fetal adrenal tissue in vitro.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Desoxycorticosterone; Fetus; Humans; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Steroid 16-alpha-Hydroxylase | 1978 |
Steroid synthesis in the adrenal gland of the sea snake Hydrophis cyanocinctus: the metabolism of exogenous precursors.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Cholesterol; Corticosterone; Desoxycorticosterone; Mitochondria; Pregnenolone; Progesterone; Snakes | 1978 |
Angiotensin stimulates both early and late steps in aldosterone biosynthesis in isolated bovine glomerulosa cells.
Topics: Adrenal Cortex; Aldosterone; Aminoglutethimide; Angiotensins; Animals; Cattle; Corticosterone; Desoxycorticosterone; Hydrocortisone; Kinetics; Pregnenolone | 1978 |
[A new method for the determination of steroidal hormones in biological material (adrenal tissue) (author's transl)].
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Chromatography, Gas; Desoxycorticosterone; Humans; Hydrocortisone; Pregnenolone; Progesterone; Testosterone | 1977 |
Steroid 21-hydroxylase activity in the ovary of the snake Storeria dekayi during pregnancy.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Corpus Luteum; Desoxycorticosterone; Female; Hydroxysteroid Dehydrogenases; Lyases; Ovary; Pregnancy; Pregnancy, Animal; Pregnenolone; Progesterone; Snakes; Steroid Hydroxylases; Steroid Isomerases; Testosterone; Time Factors | 1976 |
Adrenal mitochondrial and serum corticosteroid studies in rats resistant to adrenal-regeneration hypertension (ARH).
Topics: Adrenal Glands; Animals; Corticosterone; Desoxycorticosterone; Hypertension; Male; Mitochondria; Pregnenolone; Rats; Rats, Inbred Strains; Rats, Inbred WF; Regeneration; Stress, Physiological | 1976 |
The effect of pregnenolone, progesterone, deoxycorticosterone or corticosterone on the time of ovulation and oviposition in the hen.
Topics: Animals; Chickens; Corticosterone; Desoxycorticosterone; Female; Oviposition; Ovulation; Pregnenolone; Progesterone; Time Factors | 1976 |
Biochemical and behavioral effects of steroids on GABAA receptor function in long- and short-sleep mice.
Topics: Anesthetics; Animals; Behavior, Animal; Brain Chemistry; Chlorides; Desoxycorticosterone; Ethanol; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Pentobarbital; Pregnanediones; Pregnenolone; Receptors, GABA-A; Sleep; Species Specificity; Steroids | 1992 |
Cyclic AMP-dependent increase of steroidogenesis in brain cortical minces.
Topics: Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Desoxycorticosterone; In Vitro Techniques; Male; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley | 1992 |
Inhibition of aldosterone secretion by atrial natriuretic peptide in chicken adrenocortical cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Animals; Atrial Natriuretic Factor; Chickens; Cholera Toxin; Corticosterone; Cyclic AMP; Cyclic GMP; Desoxycorticosterone; Male; Nitroprusside; Parathyroid Hormone; Pregnenolone; Progesterone | 1989 |
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Hyperplasia, Congenital; Aldehyde-Lyases; Aldosterone; Androstenedione; Corticosterone; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Disorders of Sex Development; Humans; Hydrocortisone; Infant; Male; Mixed Function Oxygenases; Pregnenolone; Progesterone; Steroid Hydroxylases; Testosterone | 1985 |
Brain mitochondrial cytochrome P-450scc: spectral and catalytic properties.
Topics: Aminoglutethimide; Animals; Brain; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Desoxycorticosterone; Male; Mitochondria; NADP; Oxidation-Reduction; Oxidoreductases; Pregnenolone; Rats; Rats, Inbred Strains; Spectrophotometry | 1987 |
An adrenocortical tumor secreting weak mineralocorticoids.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; Adrenal Cortex Neoplasms; Adult; Carcinoma; Corticosterone; Desoxycorticosterone; Female; Humans; Hydroxyprogesterones; Hypertension; Mineralocorticoids; Pregnenolone; Progesterone | 1987 |
Effect of ketoconazole (an imidazole antimycotic agent) and other inhibitors of steroidogenesis on cytochrome P450-catalyzed reactions.
Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Aminoglutethimide; Animals; Cattle; Cholesterol; Corticosterone; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Electron Transport; In Vitro Techniques; Ketoconazole; Mitochondria; Pregnenolone; Steroids | 1986 |
In vivo secretion of 3 alpha-hydroxy-5 alpha-pregnan-20-one, a potent anaesthetic steroid, by the adrenal gland of the rat.
Topics: Adrenal Glands; Animals; Desoxycorticosterone; Female; Kinetics; Pregnanes; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains | 1985 |
Activation of solubilized steroid-transforming enzymes of adrenal microsomal origin by serum proteins.
Topics: Adrenal Glands; Animals; Beta-Globulins; Blood Proteins; Centrifugation; Desoxycorticosterone; Enzyme Activation; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Male; Microsomes; Mixed Function Oxygenases; Pregnenolone; Progesterone; Rats; Serum Albumin; Solubility; Stimulation, Chemical; Surface-Active Agents; Vibration | 1972 |
Sites of metyrapone inhibition of steroid biosynthesis by rat adrenal mitochondria.
Topics: Adrenal Glands; Animals; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Depression, Chemical; Desoxycorticosterone; Dose-Response Relationship, Drug; Glucose-6-Phosphatase; Hydroxylation; Male; Metyrapone; Mitochondria; NADH, NADPH Oxidoreductases; Pregnenolone; Rats; Receptors, Drug; Time Factors; Tritium | 1974 |
Comparative studies on mitochondrial and partially purified bovine corpus luteum cytochrome P-450.
Topics: Animals; Cattle; Cholesterol; Corpus Luteum; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Desoxycorticosterone; Electron Transport; Female; Ferredoxins; Kinetics; Mitochondria; NADP; Pregnenolone; Progesterone; Spectrum Analysis | 1973 |
Effect of steroids on germinal vesicle of oocytes of the frog (Rana pipiens) in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Aldosterone; Androgens; Animals; Anura; Cell Nucleus; Cholesterol; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Female; Hydrocortisone; In Vitro Techniques; Ovum; Pregnanediol; Pregnenolone; Progesterone; Steroids; Testosterone | 1967 |
Incorporation of 7-alpha-3h-pregnenolone and 4-14C-progesterone into corticosteroids and some of their ester sulfates by human newborn adrenal slices.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Infant, Newborn; Infant, Premature; Pregnenolone; Progesterone; Radiometry; Steroids; Sulfates; Tritium | 1967 |
Conjugation of steroid hormones by normal and neoplastic tissues.
Topics: Adult; Aged; Breast; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Female; Humans; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Middle Aged; Nandrolone; Neoplasm Metastasis; Pregnenolone; Steroids; Sulfates; Sulfur Isotopes; Transferases | 1968 |
On the occurrence of phenol and steroid sulphokinases in the human gastrointestinal tract.
Topics: Adult; Androsterone; Biopsy; Colon; Colon, Sigmoid; Dehydroepiandrosterone; Desoxycorticosterone; Estrone; Etiocholanolone; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Jejunum; Phenols; Pregnenolone; Stomach; Sulfur Isotopes; Testosterone; Transferases | 1968 |
Steroid biosynthesis in vitro and in tissue culture by adrenal tumours of mice of the CE strain.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Culture Techniques; Dehydroepiandrosterone; Desoxycorticosterone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Mice; Pregnenolone; Rodent Diseases; Steroids; Tritium | 1968 |
Steroidal and gonadotropin evaluation of a patient with a feminizing tumor of the adrenal gland. In vivo and in vitro studies.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenalectomy; Chromatography; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Estradiol; Estriol; Estrogens; Feminization; Follicle Stimulating Hormone; Gonadotropins; Humans; Hydrocortisone; In Vitro Techniques; Luteinizing Hormone; Male; Metabolism, Inborn Errors; Middle Aged; Mixed Function Oxygenases; Nephrectomy; Prednisone; Pregnenolone; Radioimmunoassay; Sex Characteristics; Tritium | 1969 |
Steroids in germfree and conventional rats. Sulpho- and glucuronohydrolase activities of caecal contents from conventional rats.
Topics: Adrenal Cortex Hormones; Animals; Bacteria; Carbon Isotopes; Cecum; Cholesterol; Chromatography, Gas; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Esters; Feces; Female; Germ-Free Life; Glucuronidase; Male; Pregnanes; Pregnenolone; Rats; Spectrum Analysis; Steroids; Sulfatases; Sulfuric Acids; Testosterone; Time Factors; Tritium | 1970 |
Conversion of dehydroepiandrosterone, pregnenolone, and progesterone by interstitial cell tumor tissue.
Topics: Androstanes; Animals; Carbon Isotopes; Chromatography; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Leydig Cell Tumor; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Progesterone; Testosterone; Tritium | 1970 |
Adrenal steroid biosynthesis from 4-14C-cholesterol (in vitro) during phenobarbital block of PMS-induced ovulation in immature rats.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Cholesterol; Chorionic Gonadotropin; Chromatography, Gas; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Gonadotropins, Equine; Hydroxyprogesterones; In Vitro Techniques; Ovulation; Phenobarbital; Pregnenolone; Progesterone; Rats | 1973 |
Inhibition of placental steroid synthesis by steroid metabolites: possible feedback control.
Topics: Carbon Isotopes; Desoxycorticosterone; Estriol; Feedback; Female; Fetus; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Kinetics; Maternal-Fetal Exchange; NAD; Oxidation-Reduction; Oxidoreductases; Placenta; Pregnancy; Pregnenolone; Progesterone | 1967 |
Congenital adrenal hyperplasia due to a deficiency of one of the enzymes involved in the biosynthesis of pregnenolone.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Desoxycorticosterone; Disorders of Sex Development; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Hypokalemia; Hyponatremia; Infant; Male; Metabolism, Inborn Errors; Mixed Function Oxygenases; Pregnanediol; Pregnanetriol; Pregnenolone; Secretory Rate; Urine; Water-Electrolyte Balance | 1968 |
Quantitative gas chromatography of adrenal cortical steroids.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Aldosterone; Androsterone; Chemical Phenomena; Chemistry; Cholesterol; Chromatography, Gas; Computers; Corticosterone; Cortisone; Dehydroepiandrosterone; Desoxycorticosterone; Hydroxyprogesterones; Methods; Periodic Acid; Pregnenolone; Progesterone | 1968 |
Cleavage of cholesterol side chain associated with cytochrome P-450, flavoprotein, and nonheme iron-protein derived from the bovine adrenal cortex.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Cattle; Cholesterol; Chromatography, Paper; Corticosterone; Crystallization; Desoxycorticosterone; Electron Transport; Electron Transport Complex IV; Ferredoxins; Flavins; Mitochondria; Models, Biological; Oxidoreductases; Pigments, Biological; Pregnenolone; Progesterone; Proteins; Spectrophotometry | 1968 |
A method of preparing adrenal cell suspensions and its applicability to the in vitro study of adrenal metabolism.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Biochemical Phenomena; Biochemistry; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Male; Methods; Pregnenolone; Progesterone; Rats; Stimulation, Chemical | 1968 |
Inhibition of adrenal cortical secretion by amino-glutethimide in dogs.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Chromatography, Paper; Corticosterone; Dehydroepiandrosterone; Depression, Chemical; Desoxycorticosterone; Dogs; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Pyridones; Veins | 1968 |
Inhibition of adrenal steroidogenesis by glutethimide.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Body Weight; Cholesterol; Corticosterone; Desoxycorticosterone; Female; Glutethimide; Hydroxyprogesterones; In Vitro Techniques; Methods; Organ Size; Pregnenolone; Rats | 1968 |
Regulation of the adrenal cortex secretory pattern by adrenocorticotropin.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Hydrocortisone; Mixed Function Oxygenases; Pituitary-Adrenal System; Pregnenolone; Progesterone; Rabbits; Stimulation, Chemical | 1967 |
In vivo and in vitro studies of steroid production by a luteoma and an adrenal cortical carcinoma in mice.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenalectomy; Androstanes; Animals; Atrophy; Carbon Isotopes; Carcinoma; Castration; Chromatography; Desoxycorticosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Ovary; Pregnenolone; Progesterone; Testosterone; Thecoma; Tritium | 1969 |
Studies on P-450. VI. The spin state of P-450 solubilized from bovine adrenocortical mitochondria.
Topics: Adrenal Glands; Animals; Blood Proteins; Carbon Monoxide; Cattle; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Glycerides; Glycols; Hydrogen-Ion Concentration; Ions; Mitochondria; Nitrogen; Pigments, Biological; Potassium Chloride; Pregnenolone; Spectrophotometry; Spectrum Analysis; Temperature | 1969 |
Kinetic studies on the biosynthesis of corticosteroids in vitro from exogenous precursors by the interrenal glands of the normal, corticotrophin-treated and adenohypophysectomized Xenopus laevis Daudin.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Anura; Carbon Isotopes; Cholesterol; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Female; Glucocorticoids; Hypophysectomy; Kinetics; Pregnenolone; Progesterone; Tritium | 1970 |
Ontogeny of adrenal function in fetal and neonatal rhesus monkeys: in vitro corticosteroidogenesis.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Body Weight; Carbon Isotopes; Chromatography, Gas; Desoxycorticosterone; Female; Fetus; Gestational Age; Haplorhini; Hydrocortisone; In Vitro Techniques; Organ Size; Pregnancy; Pregnenolone; Progesterone; Stimulation, Chemical; Tritium | 1971 |
[In vitro studies on the biosynthesis of corticosteroids in rat adrenal glands and the action of ACTH. I. Biosynthesis of corticosteroids from endogenous precursors].
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cholesterol; Corticosterone; Desoxycorticosterone; Female; In Vitro Techniques; Male; Pregnenolone; Progesterone; Rats | 1971 |
Effect of corticotrophin (Synacthen, Ciba) on compartmental arrangement of steroids in the rat adrenal cortex.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Desoxycorticosterone; Pregnenolone; Rats; Tritium | 1971 |
Compartmental arrangement of steroid precursors and the control of steroid hormone secretion in rat adrenal tissue in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Dialysis; Furosemide; Hydrocortisone; Hydroxylation; In Vitro Techniques; Pregnenolone; Progesterone; Rats; Steroids | 1971 |
A technique for the assay of 17-hydroxyprogesterone (17-hydroxy-4-pregnene-3,20-dione) in serum using celite column chromatography and competitive protein binding.
Topics: 17-Ketosteroids; Acetates; Acylation; Alcohols; Androstanes; Anhydrides; Chemical Phenomena; Chemistry; Cholesterol; Chromatography; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estriol; Estrone; Female; Gonadotropins; Humans; Hydroxyprogesterones; Infertility, Female; Male; Menopause; Methods; Pregnenolone; Progesterone; Protein Binding; Silicon Dioxide; Testosterone; Transcortin; Tritium | 1971 |
[In vitro studies on the biosynthesis of corticosteroids in the rat adrenal gland and on the effect of ACTH. II. Comparison of the synthesis from endogenous precursors with that from exogenous (4- 14 C)cholesterol, (4- 14 C)pregnenolone and (4- 14 C)proge
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cholesterol; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Kinetics; Pregnenolone; Progesterone; Rats; Time Factors | 1971 |
The effect of ether anaesthesia stress on cholesterol-side-chain cleavage and cytochrome P450 in rat-adrenal mitochondria.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anesthesia, Inhalation; Animals; Biological Transport; Carbon Isotopes; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Ethyl Ethers; Female; Isocitrates; Mitochondria; Pregnenolone; Rats; Spectrophotometry; Steroid Hydroxylases | 1972 |
Studies on P-450. IX. Properties of a P-450 preparation showing high spin type absorption spectrum obtained from adrenal cortex mitochondria.
Topics: Adrenal Glands; Animals; Carbon Monoxide; Cattle; Cholesterol; Chromatography, Gas; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Mitochondria; Pregnenolone; Spectrophotometry; Ultracentrifugation | 1972 |
Steroid metabolism in the adrenals of fetal sheep in relation to natural and corticotrophin-induced parturition.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Dehydroepiandrosterone; Desoxycorticosterone; Female; Fetus; Hydrocortisone; Labor, Induced; Labor, Obstetric; Pregnancy; Pregnenolone; Progesterone; Sheep; Steroid Hydroxylases; Sulfates; Tritium; Umbilical Arteries; Umbilical Veins | 1972 |
C 21 steroid metabolism and conjugation in the human premature neonate. 2. Tissue metabolism and conjugation of exogenous cortisol, 11-deoxycortisol, corticosterone and pregnenolone in the presence and absence of ACTH in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hydroxylation; Infant, Newborn; Infant, Premature; Intestinal Mucosa; Kidney; Liver; Lung; Male; Pregnenolone; Skin; Spleen; Thymus Gland; Tritium | 1973 |
Haem protein P-450 from the adrenal cortex: interaction with steroids and the hydroxylation reaction.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Carbon Isotopes; Chemistry, Organic; Cholesterol; Corticosterone; Cortisone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Hydroxylation; Metyrapone; Mitochondria; Organic Chemistry Phenomena; Pregnenolone; Progesterone; Pseudomonas | 1972 |
Metabolic regulation of steroidogenesis in adrenocortical carcinoma cells of rat. Effect of adrenocorticotropin and adenosine cyclic 3':5'-monophosphate on corticosteroidogenesis.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Butyrates; Carbon Isotopes; Carcinoma; Corticosterone; Cyclic AMP; Desoxycorticosterone; In Vitro Techniques; Male; Pregnenolone; Progesterone; Rats; Tritium | 1973 |
Compartmental arrangement of steroids formed from (1- 14 C)acetate by rat adrenal zona glomerulosa and the effect of corticotrophin.
Topics: Acetates; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Binding Sites; Carbon Isotopes; Chromatography; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Dialysis; Female; Hydrocortisone; Pregnenolone; Rats; Tritium | 1973 |
The biosynthesis and secretion of aldosterone by the rat adrenal zona glomerulosa, and the significance of the compartmental arrangement of steroids.
Topics: Acetates; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Binding Sites; Carbon Isotopes; Chromatography; Corticosterone; Depression, Chemical; Desoxycorticosterone; Furosemide; Hydrocortisone; Pregnenolone; Stimulation, Chemical; Tritium | 1973 |
Modification of rabbit adrenal steroid biosynthesis by prolonged ACTH administration.
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Acetylation; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Body Weight; Carbon Isotopes; Chromates; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Male; Organ Size; Oxidation-Reduction; Pregnenolone; Progesterone; Rabbits; Tritium | 1973 |
In vitro corticosteroidogenesis by the adrenal gland of the chicken (Gallus domesticus).
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Carbon Isotopes; Cell-Free System; Chickens; Corticosterone; Desoxycorticosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Microsomes; Mitochondria; Mixed Function Oxygenases; Pregnenolone; Progesterone | 1973 |
In-vitro corticosteroid synthesis in rat adrenals. I. Results indicating (an) alternative pathway(s) of synthesis without the intermediates cholesterol, pregnenolone and progesterone.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cholesterol; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Metyrapone; Pregnenolone; Progesterone; Rats; Tritium | 1973 |
Substrate-induced difference spectral, electron paramagnetic resonance, and enzymatic properties of cholesterol-depleted mitochondrial cytochrome P-450 of bovine adrenal cortex.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Acetone; Adrenal Glands; Animals; Cattle; Cholesterol; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Drug Resistance, Microbial; Drug Synergism; Electron Spin Resonance Spectroscopy; Electron Transport; Hydroxylation; Iron; Mitochondria; Oxidation-Reduction; Pregnenolone; Spectrophotometry, Ultraviolet; Surface-Active Agents | 1973 |
Metabolic regulation and adenyl cyclase activity of adrenocortical carcinoma cultured cells.
Topics: Adenylyl Cyclases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Cell Fractionation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cholesterol; Corticosterone; Cyclic AMP; Desoxycorticosterone; Epinephrine; Mitochondria; Neoplasms, Experimental; Pregnenolone; Rats | 1974 |
Regulation of aldosterone synthesis.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Bucladesine; Cattle; Chromatography, Paper; Corticosterone; Cyclic AMP; Desoxycorticosterone; DNA; In Vitro Techniques; Pregnenolone; Progesterone; Radioimmunoassay; Time Factors; Tritium; Trypsin | 1974 |
[In vitro corticosteroid biosynthesis in human adrenals. II. Comparison between normal and hyperplastic (Cushing) adrenals (author's transl)].
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aged; Aldosterone; Animals; Carbon Radioisotopes; Corticosterone; Cushing Syndrome; Desoxycorticosterone; Female; Humans; Male; Middle Aged; Pregnenolone; Rats; Stimulation, Chemical | 1974 |
Control of substrate flux and adrenal cytochrome P-450.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cattle; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Electron Transport; Microsomes; Mitochondria; Polyethylene Glycols; Pregnenolone; Rats | 1973 |
Inhibition of adrenal corticosteroidogenesis in the rat by cyanotrimethylandrostenolone, a synthetic androstane.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Desoxycorticosterone; Hydroxysteroid Dehydrogenases; In Vitro Techniques; NADP; Pregnenolone; Progesterone; Rats; Steroids | 1966 |
Further studies on corticosteroidogenesis. IV. Inhibition of utilization of biological substrates for corticoid synthesis by high calcium concentrations. Possible role of transhydrogenase in corticosteroidogenesis.
Topics: Adenosine Triphosphate; Adrenal Glands; Animals; Antimycin A; Calcium; Citrates; Corticosterone; Desoxycorticosterone; Dinitrophenols; Ferrocyanides; Hydroxybutyrates; In Vitro Techniques; Ketoglutaric Acids; Mitochondria; NADP; Oligomycins; Oxidoreductases; Pregnenolone; Rats; Succinates | 1966 |
20-alpha-Hydroxysteroid dehydrogenase and reductive pathways in mouse adrenal glands in vitro.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Desoxycorticosterone; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Metyrapone; Mice; NADP; Pregnanediol; Pregnenolone; Progesterone | 1968 |
Further studies on the 11-beta-hydroxylation of deoxycorticosterone and progesterone by rat adrenal mitochondria.
Topics: Adrenal Glands; Animals; Desoxycorticosterone; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Polarography; Pregnenolone; Progesterone; Rats | 1968 |
[On arthropod defense substances. XXVII. The C21-steroids from the prothoracic defense glands of Acilius sulcatus].
Topics: Animals; Chromatography, Thin Layer; Coleoptera; Desoxycorticosterone; Dydrogesterone; Infrared Rays; Pregnanes; Pregnenolone; Spectrum Analysis; Territoriality; Ultraviolet Rays | 1967 |
Synthesis of corticosteroids by the interrenal gland of selachian elasmobranch fish.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Glucocorticoids; In Vitro Techniques; NADP; Pregnenolone; Progesterone; Sharks; Species Specificity | 1970 |
Studies on P-450. VII. Reconstitution of a steroid 11-beta-hydroxulation system using a P-450 preparation extracted and partially purified from adenocortical mitochondria.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Corticosterone; Cytochromes; Desoxycorticosterone; Fluorometry; Hydrogen-Ion Concentration; Mitochondria; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pigments, Biological; Pregnenolone; Spectrophotometry | 1970 |
Steroids influencing the toxicity of L-tyrosine.
Topics: Adrenal Cortex Hormones; Animals; Cholesterol; Desoxycorticosterone; Diet; Edema; Ethylestrenol; Eye; Eyelids; Female; Oxandrolone; Pancreas; Poisoning; Prednisolone; Pregnanediones; Pregnenolone; Rats; Spironolactone; Thyroxine; Triamcinolone; Tyrosine | 1971 |
Steroid hydroxylation in bovine adrenocortical mitochondria. Competition between side-chain cleavage of cholesterol and 11 beta hydroxylation.
Topics: Adrenal Glands; Animals; Calcium; Carbon Isotopes; Cattle; Cell Fractionation; Cholesterol; Corticosterone; Cytochromes; Depression, Chemical; Desoxycorticosterone; Feedback; In Vitro Techniques; Kinetics; Metyrapone; Mitochondria; Mixed Function Oxygenases; NADP; Pregnenolone | 1971 |
Steroid biosynthesis by the American bullfrog (Rana catesbeiana) interrenals. I. In vitro studies with progesterone-4-14 C and delta 5-pregnenolone-4-14 C.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Anura; Carbon Isotopes; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Mitochondria; Mixed Function Oxygenases; NADP; Pregnanes; Pregnenolone; Progesterone | 1971 |
Studies on P-450. 8. Effects of steroids on the reaction with oxygen and the rate of reduction of partially purified P-450 from adrenocortical mitochondria.
Topics: Adrenal Glands; Animals; Cattle; Cytochromes; Depression, Chemical; Desoxycorticosterone; Hydroxylation; In Vitro Techniques; Kinetics; Mitochondria; NADP; Oxidation-Reduction; Oxygen Consumption; Pigments, Biological; Pregnenolone; Spectrophotometry; Stimulation, Chemical; Sulfur | 1971 |
[Anticatatoxic hormones].
Topics: Animals; Desoxycorticosterone; Digitoxin; Drug Antagonism; Drug Synergism; Estradiol; Female; Glucocorticoids; Indomethacin; Mineralocorticoids; Nitriles; Pregnanediones; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Spironolactone; Thyroxine; Triamcinolone | 1972 |
Metabolism of (4-14C) cholesterol by human adrenal glands in vitro and its inhibition by metyrapone.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Adult; Androstenedione; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Corticosterone; Depression, Chemical; Desoxycorticosterone; Female; Humans; Hydrocortisone; In Vitro Techniques; Metyrapone; Middle Aged; Pregnenolone; Progesterone; Tritium | 1974 |
Low-speed preparation of microsomes from testis, ovary and adrenal: a comparative study.
Topics: Adrenal Glands; Animals; Calcium; Carbon Radioisotopes; Chromatography, Thin Layer; Desoxycorticosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Isomerases; Lyases; Male; Microsomes; Ovary; Pregnenolone; Progesterone; Proteins; Rats; Steroid Hydroxylases; Testis; Testosterone | 1974 |
Biosynthesis of 11-deoxycorticosterone by the ovary of the yucca night lizard, Xantusia vigilis.
Topics: Androstenedione; Animals; Carbon Radioisotopes; Desoxycorticosterone; Female; Humans; Lizards; Ovary; Pregnenolone; Progesterone; Steroid Hydroxylases | 1974 |
Proceedings: Functional interrelationship between the zona glomerulosa and the inner zones of the rat adrenal cortex incubated in vitro.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Chromatography, Paper; Culture Media; Desoxycorticosterone; Hydroxycorticosteroids; In Vitro Techniques; Pregnenolone; Radioligand Assay; Rats; Tritium | 1974 |
[In vitro corticosteroid biosynthesis in human adrenals. I. Incubation of slices and homogenates of fresh tissue and of freeze stored tissue (author's transl)].
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Carbon Radioisotopes; Chromatography, Gas; Chromatography, Thin Layer; Corticosterone; Culture Techniques; Desoxycorticosterone; Freezing; Humans; Hydrocortisone; Male; Middle Aged; Pregnenolone; Progesterone; Tissue Preservation | 1974 |
Induction of structural alterations in the preovulatory amphibian ovarian follicle by hormones.
Topics: Animals; Cells, Cultured; Cycloheximide; Depression, Chemical; Desoxycorticosterone; Estradiol; Estriol; Estrone; Female; Hormones; In Vitro Techniques; Micromanipulation; Ovarian Follicle; Pituitary Gland; Pregnenolone; Progesterone; Protein Biosynthesis; Puromycin; Rana pipiens; Testosterone | 1972 |
Protection against the neurolathyrism produced by arsanilic acid in the rat.
Topics: 5-Hydroxytryptophan; Animals; Arsenic Poisoning; Biotransformation; Desoxycorticosterone; Female; Hormones; Movement Disorders; Phenobarbital; Phenytoin; Pregnenolone; Rats; Serotonin; Steroids; Thyroxine; Triamcinolone | 1972 |
Steroid secretion by rat adrenal glands during the first week following adrenal enucleation.
Topics: Adrenal Glands; Adrenalectomy; Animals; Corticosterone; Desoxycorticosterone; Male; Pregnenolone; Progesterone; Rats; Regeneration; Sodium; Time Factors | 1972 |
Effect of exogenous steroids and inhibitors of steroidogenesis on endotoxin shock.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Androstenedione; Animals; Butanones; Corticosterone; Desoxycorticosterone; Endotoxins; Hydrocortisone; Hydroxyprogesterones; Lethal Dose 50; Male; Metyrapone; Mice; Mice, Inbred ICR; Pregnenes; Pregnenolone; Progesterone; Shock, Septic | 1973 |
Secretion of 17-deoxycorticosteroids by herring gull (Larus argentatus) adrenals.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Aldosterone; Animals; Birds; Chromatography, Gas; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Pregnenolone; Tritium | 1973 |
Transformation of ( 14 C)-pregnenolone and production of corticosteroids by adrenal glands from rats bearing a transplantable mammotropic pituitary tumor.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Female; Glycerophosphates; Hydroxybutyrates; Hydroxycorticosteroids; Hydroxylation; Kinetics; Male; Mitochondria; Pituitary Neoplasms; Pregnenolone; Rats | 1973 |
Metabolic regulation of steroid steroidogenesis in isolated adrenal and adrenocortical carcinoma cells of rat. The incorporation of (20S)-20-(7- 3 H)hydroxycholesterol into deoxycorticosterone and corticosterone.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Animals; Carbon Isotopes; Carcinoma; Cholesterol; Chromatography, Thin Layer; Corticosterone; Desoxycorticosterone; Pregnenolone; Rats; Tritium | 1973 |
Production of steroids in vivo by regenerated adrenal glands of hypertensive and normotensive rats.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Female; Heart; Hydroxycorticosteroids; Hypertension; Ketosteroids; Kidney; Nephrectomy; Organ Size; Pregnenes; Pregnenolone; Progesterone; Rats; Regeneration; Secretory Rate; Thymus Gland | 1973 |
A specific progesterone-binding component of human breast cyst fluid.
Topics: Blood Proteins; Body Fluids; Breast Diseases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysts; Desoxycorticosterone; Dextrans; Electrophoresis, Disc; Estradiol; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Molecular Weight; Pregnenolone; Progesterone; Protein Binding; Proteins; Serum Globulins; Structure-Activity Relationship; Testosterone; Tritium | 1973 |
Steroid biosynthesis by phalarope (Steganopus tricolor and Lobipes lobatus) adrenal tissue.
Topics: Adrenal Glands; Animals; Birds; Carbon Radioisotopes; Corticosterone; Desoxycorticosterone; Female; Male; Pregnenolone; Progesterone; Sex Factors; Time Factors | 1973 |
Porphobilinogen oxygenase from rat liver: induction, isolation, and properties.
Topics: Allosteric Regulation; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Desoxycorticosterone; Enzyme Induction; Female; Hydrogen-Ion Concentration; Iron; Kinetics; Magnesium; Microsomes, Liver; Oxygenases; Phenobarbital; Porphobilinogen; Pregnenolone; Progesterone; Rats; Species Specificity; Structure-Activity Relationship; Temperature | 1973 |
On the steroid specificity of the pregnant guinea pig progesterone-binding globulin.
Topics: Animals; Binding, Competitive; Corticosterone; Desoxycorticosterone; Dialysis; Dihydrotestosterone; Estrogens; Female; Globulins; Guinea Pigs; Humans; Hydrocortisone; Mathematics; Pregnancy; Pregnancy, Animal; Pregnanediol; Pregnanediones; Pregnenolone; Progesterone; Protein Binding; Steroids; Testosterone; Tritium | 1973 |
Spectral properties of rat adrenal-mitochondrial cytochrome P-450.
Topics: Adrenal Glands; Animals; Binding Sites; Carbon Radioisotopes; Cattle; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Ethyl Ethers; Female; Hydrogen-Ion Concentration; Male; Mitochondria; Pregnenolone; Protein Binding; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Stress, Physiological; Time Factors | 1974 |
Deficient 17-hydroxylation in a corticosterone producing adrenal tumor from an infant with hemihypertrophy and visceromegaly.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abnormalities, Multiple; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Corticosterone; Desoxycorticosterone; Female; Growth Hormone; Humans; Hydrocortisone; Hydroxyprogesterones; Hyperplasia; Hypoglycemia; Infant; Islets of Langerhans; Kidney Diseases; Metabolism, Inborn Errors; Mixed Function Oxygenases; Pregnanediol; Pregnanetriol; Pregnenolone; Vanilmandelic Acid | 1970 |
In vitro biosynthesis of steroids by adrenals of Macaca mulatta.
Topics: 17-Ketosteroids; Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Chromatography, Paper; Corticosterone; Culture Techniques; Desoxycorticosterone; Female; Haplorhini; Hydrocortisone; Pregnenolone; Progesterone; Tritium | 1968 |
[Action of C 21 steroids on cancerization of rat liver by para-dimethylaminoazobenzene (DAB)].
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cell Transformation, Neoplastic; Corticosterone; Desoxycorticosterone; Dexamethasone; Dichlorodiphenyldichloroethane; Hydrocortisone; Hydroxyprogesterones; Liver Neoplasms; Liver Regeneration; Male; p-Dimethylaminoazobenzene; Pregnenolone; Progesterone; Rats | 1969 |
A comparative study of adrenal steroid biosynthesis in two species of monkeys.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Androstanes; Animals; Biotransformation; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Corticosterone; Desoxycorticosterone; Haplorhini; Hydrocortisone; Ketosteroids; Macaca; Male; Pregnanes; Pregnenolone; Progesterone; Species Specificity; Sterols; Tritium | 1970 |
In vitro inhibition of aldosterone biosynthesis by 17-hydroxylated steroids in rat adrenal.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Rats; Tritium | 1972 |
A new male pseudo-hermaphroditism associated with hypertension due to a block of 17 -hydroxylation.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aldosterone; Corticosterone; Desoxycorticosterone; Dexamethasone; Disorders of Sex Development; Estrogens; Humans; Hydroxycorticosteroids; Hypertension; Hypokalemia; Karyotyping; Male; Metabolic Diseases; Mixed Function Oxygenases; Pregnanediol; Pregnenolone; Progesterone | 1972 |
A comparison of steroidogenesis in vitro in two teleosts, the marine herring, Clupea, and the freshwater Atlantic salmon, Salmo.
Topics: Animals; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Corticosterone; Crystallization; Desoxycorticosterone; Fishes; Hydrocortisone; Hydroxylation; Kidney; Pregnenolone; Progesterone; Salmonidae; Steroids; Tritium | 1972 |
A specific radioimmunoassay of plasma progesterone.
Topics: Animals; Chromatography; Cross Reactions; Desoxycorticosterone; Female; Humans; Hydroxyprogesterones; Immune Sera; Male; Menopause; Methods; Ovulation; Pregnenolone; Progesterone; Radioimmunoassay; Serum Albumin, Bovine; Sheep; Succinates; Tritium | 1972 |
Facilitation of ovulation by steroids in immature rats primed with pregnant mare serum gonadotropin.
Topics: Aldosterone; Animals; Corticosterone; Cortisone; Desoxycorticosterone; Drug Synergism; Female; Gonadotropins, Equine; Horses; Hydroxyprogesterones; Immune Sera; Ovulation; Pregnancy; Pregnanes; Pregnenolone; Progesterone; Progestins; Rats; Time Factors | 1972 |
The association of steroids with blood cells in vivo.
Topics: Aldosterone; Animals; Blood Cells; Carbon Isotopes; Chromatography, Gas; Corticosterone; Desoxycorticosterone; Dogs; Erythrocytes; Glucocorticoids; Guinea Pigs; Hydrocortisone; Hydroxysteroids; Isomerism; Mineralocorticoids; Pregnenolone; Progesterone; Rabbits; Rats; Species Specificity; Tetrazolium Salts | 1972 |
Steroidal free radicals as possible intermediates in the biosynthesis of C19-delta 16-steroids.
Topics: Androstanes; Animals; Biotransformation; Chromatography, Thin Layer; Desoxycorticosterone; Free Radicals; In Vitro Techniques; Lead; Male; Models, Chemical; Pregnenolone; Progesterone; Steroids; Swine; Testis; Tritium | 1970 |
Corticosteroid synthesis in vitro by adrenal tissue from newborn anencephalic infants.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Anencephaly; Carbon Isotopes; Chromatography; Corticosterone; Desoxycorticosterone; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Infant, Newborn; Pregnenolone; Progesterone; Tritium | 1969 |
Prevention of digitoxin poisoning by various steroids.
Topics: Anabolic Agents; Androstanes; Animals; Body Weight; Desoxycorticosterone; Digitoxin; Diuretics; Estradiol; Ethisterone; Ethylestrenol; Female; Fluoxymesterone; Hydrocortisone; Ketones; Methyltestosterone; Nandrolone; Norethandrolone; Norethynodrel; Organ Size; Oxandrolone; Oxymetholone; Poisoning; Pregnanes; Pregnenolone; Progesterone; Pyrazines; Rats; Spironolactone; Testosterone; Triamterene | 1969 |
Steroid biosynthesis in a feminizing adrenal carcinoma.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Adult; Aldosterone; Androstanes; Biotransformation; Carbon Isotopes; Carcinoma; Chromatography; Corticosterone; Desoxycorticosterone; Estrone; Feminization; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Sex Characteristics; Steroids; Testosterone; Tritium | 1969 |
18-hydroxylation by human adrenal tissue in vitro.
Topics: Adrenal Glands; Aldosterone; Breast Neoplasms; Carbon Isotopes; Corticosterone; Crystallization; Desoxycorticosterone; Glucocorticoids; Humans; Hyperaldosteronism; In Vitro Techniques; Mixed Function Oxygenases; Pregnenolone; Progesterone | 1970 |
Steroids in the defensive secretion of the water beetle, Cybister limbatus. I.
Topics: Animals; Chromatography, Thin Layer; Coleoptera; Desoxycorticosterone; Exocrine Glands; Infrared Rays; Magnetic Resonance Spectroscopy; Pheromones; Pregnanes; Pregnenolone; Spectrum Analysis | 1970 |
Steroid biosynthesis in vitro by foetal and adult sheep adrenal tissue.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Animals; Corticosterone; Desoxycorticosterone; Fetus; Hydrocortisone; In Vitro Techniques; Pregnenolone; Progesterone; Sheep; Steroids; Transferases | 1970 |
Enzymatic and spectral properties of solubilized cytochrome P-450 from bovine adrenocortical mitochondria.
Topics: Adrenal Glands; Animals; Cattle; Chemical Phenomena; Chemistry; Cholesterol; Cytochromes; Desoxycorticosterone; Mitochondria; Mixed Function Oxygenases; Pregnenolone; Spectrophotometry; Sulfuric Acids | 1970 |
Steroid formation in porcine ovarian tissue in vitro. The effect of human chorionic gonadotrophin.
Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Chorionic Gonadotropin; Culture Techniques; Desoxycorticosterone; Female; Humans; Ovary; Pregnenolone; Progesterone; Secretory Rate; Swine; Tritium | 1970 |
Steroids of a chondrostean: in-vitro steroidogenesis in yellow bodies isolated from kidneys and along the posterior cardinal veins of the American Atlantic sturgeon, Acipenser oxyrhynchus Mitchill.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Cholesterol; Chromatography; Corticosterone; Cortisone; Desoxycorticosterone; Female; Fishes; Glucocorticoids; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Kidney; Male; Pregnenolone; Progesterone; Tritium | 1970 |
Mechanism of control of steroid hormone secretion by the rat adrenal cortex.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Pregnenolone; Progesterone; Rats; Secretory Rate | 1970 |
Absorption and enterohepatic circulation of neutral steroids in the rat.
Topics: Animals; Biliary Fistula; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Digestive System; Female; Glucuronates; Hydrolysis; Injections; Intestinal Absorption; Pregnenolone; Rats; Sulfates | 1971 |
Accelerating effect of hydrocortisone on the keratinization of chick embryonic skin growing in a chemically defined medium.
Topics: Amino Acids; Animals; Ascorbic Acid; Chick Embryo; Culture Media; Culture Techniques; Desoxycorticosterone; Eosinophils; Hydrocortisone; Keratins; Pregnenolone; Progesterone; Proteins; Skin | 1971 |
Steroidogenesis in the blue crab Callinectes sapidus Rathbun.
Topics: 17-Ketosteroids; Androstanes; Animals; Chromatography, Thin Layer; Crustacea; Crystallization; Desoxycorticosterone; Endocrine Glands; Hydroxyprogesterones; In Vitro Techniques; Liver; Male; Pancreas; Pregnenolone; Progesterone; Steroids; Testosterone; Tritium; Vas Deferens | 1971 |
Soluble cytochrome P.450 from bovine adrenocortical mitochondria.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Cattle; Cell Fractionation; Chemical Precipitation; Cholesterol; Chromatography; Corticosterone; Cytochromes; Desoxycorticosterone; Dialysis; Mitochondria; Mixed Function Oxygenases; Pregnenolone; Quaternary Ammonium Compounds; Solubility; Spectrophotometry; Sterols; Sulfates; Tritium; Ultraviolet Rays | 1971 |
Seasonal variations in production in vitro of corticosteroids by the frogs (Rana rugulosa) adrenal.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Anura; Carbon Isotopes; Chromatography; Corticosterone; Desoxycorticosterone; Glucocorticoids; In Vitro Techniques; Organ Size; Pregnenolone; Progesterone; Seasons; Tritium | 1971 |
Steroid biosynthesis in vitro by transplantable interstitial cell tumor of mice. I. Identification and quantitative determination of the metabolites and intracellular distributon of the enzymes related to testosterone formation.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Desoxycorticosterone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Lyases; Male; Mice; Mixed Function Oxygenases; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Progesterone; Testicular Neoplasms; Testosterone | 1968 |
Alterations of aldosterone biosynthesis by rat adrenal tissue due to increased intake of sodium and potassium.
Topics: Adrenal Glands; Aldosterone; Animals; Corticosterone; Desoxycorticosterone; Diet; Female; In Vitro Techniques; Potassium; Potassium Chloride; Pregnenolone; Progesterone; Rats; Sodium; Sodium Chloride; Sucrose; Tritium | 1968 |
Percutaneous absorption of steroids.
Topics: 17-alpha-Hydroxypregnenolone; Administration, Topical; Aldosterone; Anti-Inflammatory Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Corticosterone; Cortisone; Desoxycorticosterone; Diffusion; Estradiol; Estriol; Estrone; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Skin Absorption; Steroids; Testosterone | 1969 |
In vitro transformation of steroids by the head kidney, the body kidney, and the corpuscles of Stannius of the rainbow trout (Salmo gairdneri).
Topics: Adrenal Glands; Androstanes; Animals; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Desoxycorticosterone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Isomerases; Kidney; Lyases; Mixed Function Oxygenases; Pregnanes; Pregnenolone; Progesterone; Salmonidae | 1969 |
Pathways for the biosynthesis of corticosteroids from pregnenolone by adrenal tissue of the frog, Rana rugulosa.
Topics: Adrenal Glands; Aldosterone; Animals; Anura; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Glucocorticoids; In Vitro Techniques; Kinetics; Male; Physiology, Comparative; Pregnenolone; Progesterone; Time Factors; Tritium | 1969 |
Relationships between steroid binding and elevation of alkaline phosphatase in HeLa cells.
Topics: Adrenal Cortex Hormones; Alkaline Phosphatase; Binding Sites; Chemical Phenomena; Chemistry; Cortisone; Culture Techniques; Desoxycorticosterone; HeLa Cells; Prednisolone; Prednisone; Pregnanes; Pregnenolone; Progesterone; Sterols; Stimulation, Chemical; Trypsin | 1969 |
Reactions of 20-hydroxylated steroids with bovine adrenal tissue preparations.
Topics: Adrenal Glands; Animals; Cattle; Cholestanes; Desoxycorticosterone; Methods; Mitochondria; Pregnanes; Pregnenolone; Progesterone | 1969 |
Pregnenolone and progesterone metabolism in human adrenals from twin female fetuses.
Topics: Adrenal Glands; Androgens; Chromatography; Corticosterone; Desoxycorticosterone; Female; Fetus; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnancy; Pregnancy in Diabetics; Pregnenolone; Progesterone | 1965 |
Biosynthesis of C-18-oxygenated steroids by an aldosterone-secreting human adrenal tumor. Metabolism of [4-14C] progesterone, [1,2-3H]11-deoxycorticosterone, and [4-14C] pregnenolone.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Chromatography, Paper; Chromatography, Thin Layer; Desoxycorticosterone; Female; Humans; Hyperaldosteronism; In Vitro Techniques; Pregnenolone; Progesterone; Subcellular Fractions | 1965 |
Stimulation of steroid transformations in adrenal mitochondria by cyclic 3',5'-adenosine phosphate.
Topics: Adenine Nucleotides; Adrenal Cortex Hormones; Adrenal Glands; Animals; Cholesterol; Chromatography, Thin Layer; Desoxycorticosterone; In Vitro Techniques; Mitochondria; Pregnenolone; Rats; Subcellular Fractions | 1965 |
Pathways of corticosteroid biosynthesis from pregnenolone and progesterone in rat adrenal glands.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Pregnenolone; Progesterone; Rats; Tritium | 1966 |
Progesterone-mediated increases of leucocyte alkaline phosphatase in rabbits.
Topics: 17-Hydroxycorticosteroids; Alkaline Phosphatase; Animals; Dactinomycin; Desoxycorticosterone; Estradiol; Estrone; Fluorometry; Hydrogen-Ion Concentration; Injections; Kinetics; Leukocytes; Male; Penicillins; Pregnenolone; Progesterone; Puromycin; Rabbits; Testosterone | 1966 |
Color characterization of adrenal corticoids on thin-layer chromatograms.
Topics: Adrenal Cortex Hormones; Aldosterone; Chromatography, Thin Layer; Corticosterone; Cortisone; Desoxycorticosterone; Hydrocortisone; Pregnenolone; Progesterone; Sulfuric Acids | 1966 |
Structure-function relationships of various steroids relative to induction of a specific oviduct protein (Avidin).
Topics: Androgens; Animals; Antimetabolites; Chemical Phenomena; Chemistry; Desoxycorticosterone; Diethylstilbestrol; Ethisterone; Female; Hydroxyprogesterones; Oviducts; Poultry; Pregnenolone; Progesterone; Progestins; Protein Biosynthesis; Steroids | 1967 |
Enzyme induction by corticosteroids in embryonic cells: steroid structure and inductive effect.
Topics: 17-Hydroxycorticosteroids; Aldosterone; Algestone Acetophenide; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Cholesterol; Corticosterone; Culture Techniques; Desoxycorticosterone; Enzyme Induction; Glutamine; Hydrocortisone; Hydroxyprogesterones; Ligases; Pregnenolone; Progesterone; Progestins; Retina | 1967 |
Role of 21-hydroxypregnenolone in the synthesis of corticosterone from pregnenolone by sheep adrenal tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Sheep; Tritium | 1967 |
Pathways of corticosteroid biosynthesis in duck adrenal glands.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Carbon Isotopes; Desoxycorticosterone; Ducks; In Vitro Techniques; Pregnenolone; Progesterone; Tritium | 1967 |
[The effects of o,p'-DDD on human adrenal steroid synthesis].
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Child, Preschool; Cushing Syndrome; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Middle Aged; Mitotane; Pregnenolone | 1984 |
Progesterone binding protein in the bovine corpus luteum.
Topics: Alpha-Globulins; Animals; Binding, Competitive; Cattle; Centrifugation, Density Gradient; Corpus Luteum; Cytosol; Danazol; Desoxycorticosterone; Female; Pregnancy; Pregnanediones; Pregnenolone; Progesterone; Progesterone-Binding Globulin; Promegestone | 1981 |
The origin of and metabolic fate of deoxycorticosterone and deoxycorticosterone sulfate in pregnant women and their fetuses.
Topics: Adrenocorticotropic Hormone; Desoxycorticosterone; Dexamethasone; Female; Fetus; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnenolone; Progesterone; Steroid 21-Hydroxylase; Sulfatases; Tissue Distribution | 1984 |
Production, characterization and clinical application of antisera to cortisol.
Topics: Aldosterone; Animals; Desoxycorticosterone; Hydrocortisone; Hydroxycorticosteroids; Immune Sera; Oximes; Pregnenolone; Progesterone; Protein Binding; Rabbits; Radioimmunoassay; Testosterone | 1983 |
Sterol carrier protein2. Delivery of cholesterol from adrenal lipid droplets to mitochondria for pregnenolone synthesis.
Topics: Adrenal Glands; Animals; Carrier Proteins; Cholesterol; Corticosterone; Desoxycorticosterone; Lipid Metabolism; Mitochondria; Plant Proteins; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains | 1982 |
Reptilian (Chrysemys picta) hepatic progesterone receptors: relationship to plasma steroids and the vitellogenic cycle.
Topics: Animals; Binding, Competitive; Cell Extracts; Cell Nucleus; Cytosol; Desoxycorticosterone; Estradiol; Female; Liver; Mifepristone; Pregnenolone; Progesterone; Progesterone Congeners; Promegestone; Receptors, Progesterone; Seasons; Turtles; Vitellogenesis | 1995 |
Neurosteroids in the brain of handling-habituated and naive rats: effect of CO2 inhalation.
Topics: Administration, Inhalation; Animals; Brain Chemistry; Carbon Dioxide; Cerebral Cortex; Desoxycorticosterone; Electroshock; Handling, Psychological; Hippocampus; Male; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Steroids | 1994 |
Electron leakage from the adrenal cortex mitochondrial P450scc and P450c11 systems: NADPH and steroid dependence.
Topics: Adrenal Cortex; Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Transport; Hydrocortisone; Hydrogen Peroxide; Hydroxylation; Hydroxytestosterones; Kinetics; Mitochondria; NADP; Oxidation-Reduction; Pregnenolone; Steroid 11-beta-Hydroxylase; Steroids; Superoxides | 1995 |
The interaction of biogenic amines with adrenal cytochrome P450-dependent enzymes.
Topics: Adrenal Cortex; Aminoglutethimide; Animals; Biogenic Amines; Cattle; Cell Line; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Isoenzymes; Metanephrine; Microsomes; Pregnenolone; Progesterone; Sheep; Transfection | 1993 |
Steroid production in the thymus: implications for thymocyte selection.
Topics: Aging; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Epithelial Cells; Epithelium; Fetus; Lymphocyte Depletion; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Organ Culture Techniques; Pregnenolone; Receptors, Antigen, T-Cell; Receptors, Glucocorticoid; Signal Transduction; T-Lymphocytes; Thymus Gland | 1994 |
Competition for electron transfer between cytochromes P450scc and P45011 beta in rat adrenal mitochondria.
Topics: Adrenal Cortex; Adrenodoxin; Aminoglutethimide; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cosyntropin; Desoxycorticosterone; Electron Transport; Female; Ferredoxin-NADP Reductase; Isocitrates; Isoenzymes; Metyrapone; Mitochondria; NADP; Oxidation-Reduction; Pregnenolone; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Succinates; Succinic Acid | 1993 |
Inhibition of corticosteroid production by sodium pentobarbitone in rat adrenocortical preparations.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Animals; Bucladesine; Cells, Cultured; Corticosterone; Depression, Chemical; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Male; Pentobarbital; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains | 1993 |
Thyrotropin-releasing hormone inhibits glucocorticoid secretion of rat adrenal cortex: in vivo and in vitro studies.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Chromatography, High Pressure Liquid; Corticosterone; Desoxycorticosterone; Glucocorticoids; Male; Pregnenolone; Progesterone; Rats; Rats, Wistar; Thyrotropin-Releasing Hormone | 1993 |
Transforming growth factor-beta 1 inhibits aldosterone biosynthesis in cultured bovine zona glomerulosa cells.
Topics: Aldosterone; Angiotensin II; Animals; Cattle; Cell Survival; Cells, Cultured; Corticosterone; Desoxycorticosterone; Kinetics; Mineralocorticoid Receptor Antagonists; Potassium; Pregnenolone; Transforming Growth Factor beta; Zona Glomerulosa | 1993 |
Neurosteroidal modulation of social isolation-induced decrease in pentobarbital sleep in mice.
Topics: Adrenalectomy; Allosteric Regulation; Analysis of Variance; Animals; Anti-Anxiety Agents; Brain; Corticotropin-Releasing Hormone; Desoxycorticosterone; GABA-A Receptor Antagonists; Male; Methoxamine; Mice; Mice, Inbred Strains; Pentobarbital; Pregnenolone; Receptors, GABA-A; Sleep; Social Behavior; Social Isolation; Stress, Psychological; Yohimbine | 1996 |
Steroid inhibition of [3H]SR 95531 binding to the GABAA recognition site.
Topics: Allosteric Regulation; Androstanes; Animals; Azasteroids; Cell Membrane; Cerebral Cortex; Desoxycorticosterone; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pregnanolone; Pregnenolone; Protein Binding; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids | 1996 |
Delta subunit inhibits neurosteroid modulation of GABAA receptors.
Topics: Allosteric Regulation; Anesthetics; Animals; Cells, Cultured; Cerebellum; Chlorides; Desoxycorticosterone; DNA, Complementary; GABA-A Receptor Agonists; Gene Expression Regulation, Developmental; Ion Channel Gating; Membrane Potentials; Neurons; Patch-Clamp Techniques; Polymerase Chain Reaction; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1996 |
Isoniazid-induced inhibition of GABAergic transmission enhances neurosteroid content in the rat brain.
Topics: Animals; Anti-Anxiety Agents; Brain Chemistry; Carbolines; Desoxycorticosterone; Electroshock; GABA Antagonists; GABA-A Receptor Antagonists; Isoniazid; Male; Neurotransmitter Agents; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Steroids | 1996 |
Direct inhibitions of the activities of steroidogenic cytochrome P-450 mono-oxygenase systems by anticonvulsants.
Topics: Adrenodoxin; Androstenedione; Animals; Anticonvulsants; Aromatase; Cattle; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Estrogens; Estrone; Female; Ferredoxin-NADP Reductase; Humans; Male; Microsomes; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Placenta; Pregnancy; Pregnenolone; Progesterone; Rats; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Steroids; Testis | 1997 |
Majonoside-R2 reverses social isolation stress-induced decrease in pentobarbital sleep in mice: possible involvement of neuroactive steroids.
Topics: Animals; Corticotropin-Releasing Hormone; Desoxycorticosterone; Dose-Response Relationship, Drug; Ginsenosides; Hormone Antagonists; Hypnotics and Sedatives; Male; Mice; Pentobarbital; Peptide Fragments; Pregnenolone; Receptors, GABA-A; Saponins; Sleep; Social Isolation; Stress, Physiological | 1997 |
Effects of PKC activation and receptor desensitization on neurosteroid modulation of GABA(A) receptors.
Topics: Animals; Anti-Anxiety Agents; Chloride Channels; Desoxycorticosterone; Enzyme Activation; Female; gamma-Aminobutyric Acid; Humans; Kinetics; Oocytes; Phorbol Esters; Pregnenolone; Protein Kinase C; Receptors, GABA-A; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Xenopus laevis | 1997 |
Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes.
Topics: Ammonia; Astrocytes; Atrial Natriuretic Factor; Benzodiazepines; Benzodiazepinones; Brain Edema; Cell Size; Clonazepam; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Diazepam; Diazepam Binding Inhibitor; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoquinolines; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Pregnanolone; Pregnenolone; Protoporphyrins; Receptors, GABA-A; Steroids; Up-Regulation | 1998 |
The effects of neurosteroids on rat behavior and 3H-muscimol binding in the brain.
Topics: Animals; Anti-Anxiety Agents; Autoradiography; Behavior, Animal; Brain Chemistry; Conflict, Psychological; Desoxycorticosterone; Dose-Response Relationship, Drug; Drinking Behavior; Fear; GABA Agonists; GABA Modulators; Injections, Intraventricular; Male; Midazolam; Muscimol; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Steroids | 1999 |
Inhibition of aldosterone production by testosterone in male rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Cells, Cultured; Corticosterone; Cyclic AMP; Desoxycorticosterone; Male; Mineralocorticoid Receptor Antagonists; Orchiectomy; Pregnenediones; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Testosterone; Zona Glomerulosa | 1999 |
Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies.
Topics: Animals; Cloning, Molecular; Desoxycorticosterone; Female; Humans; Imidazoles; Isoquinolines; Ligands; Male; Oocytes; Pregnenolone; Progesterone; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship; Xenopus | 1999 |
Direct effects of prolactin on corticosterone release by zona fasciculata-reticularis cells from male rats.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Animals; Bromocriptine; Cells, Cultured; Cerebral Cortex; Colforsin; Corticosterone; Cyclic AMP; Desoxycorticosterone; Hyperprolactinemia; Injections, Subcutaneous; Male; Nifedipine; Pituitary Gland, Anterior; Pregnenolone; Progesterone; Prolactin; Rats; Rats, Sprague-Dawley; Sheep; Zona Fasciculata; Zona Reticularis | 1999 |
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.
Topics: Animals; Anxiety; Brain; Cerebral Cortex; Conflict, Psychological; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Electroshock; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Oocytes; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Social Isolation; Steroids; Synaptosomes; Time Factors; Xenopus laevis | 2000 |
Biosynthesis and metabolism of steroid hormones by human adrenal carcinomas.
Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Bucladesine; Carcinoma; Cell Culture Techniques; Citric Acid Cycle; Desoxycorticosterone; Humans; Metyrapone; Mitochondria; Pregnenolone; Steroid 11-beta-Hydroxylase | 2000 |
The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol.
Topics: Animals; Bicuculline; Central Nervous System Depressants; Convulsants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Picrotoxin; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Reflex; Seizures; Sleep; Steroids | 2000 |
Stimulation of pregnenolone metabolism and aromatase activity by luteinizing hormone in mouse uterus.
Topics: Androstenedione; Animals; Aromatase; Chromatography, High Pressure Liquid; Desoxycorticosterone; Diestrus; Female; Luteinizing Hormone; Mice; Ovariectomy; Pregnenes; Pregnenolone; Progesterone; Sheep; Uterus | 2000 |
Pregnenolone sulfate, dehydroepiandrosterone sulfate and allotetrahydrodeoxycorticosterone affect rapid tolerance to the hypothermic effect of ethanol.
Topics: Alcoholism; Animals; Body Temperature; Central Nervous System Depressants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Drug Interactions; Drug Tolerance; Ethanol; Hypothermia; Male; Mice; Pregnenolone | 2002 |
Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.
Topics: Anesthetics; Animals; Desoxycorticosterone; Evoked Potentials; Female; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neural Pathways; Pregnenolone; Receptors, GABA-A; Synapses; Thalamus | 2003 |
Neurosteroid secretion in panic disorder.
Topics: Adult; Analysis of Variance; Case-Control Studies; Dehydroepiandrosterone; Desoxycorticosterone; Female; Humans; Panic Disorder; Pregnenolone; Progesterone | 2003 |
Ghrelin, an endogenous ligand for the growth hormone-secretagogue receptor, is expressed in the human adrenal cortex.
Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Autoradiography; Binding Sites; Chromatography, High Pressure Liquid; Corticosterone; Cortodoxone; Desoxycorticosterone; Ghrelin; Humans; Hydrocortisone; In Vitro Techniques; Ligands; Middle Aged; Peptide Hormones; Pregnenolone; Progesterone; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
An evaluation of pregnenolone and a combination of desoxycorticosterone acetate-sodium ascorbate in the treatment of arthritis.
Topics: Arthritis; Arthritis, Rheumatoid; Ascorbic Acid; Desoxycorticosterone; Desoxycorticosterone Acetate; Pregnenolone; Vitamins | 1952 |
[Plasma volume and thiocyanate space after treatment with adrenocortical hormones and other substances with antidiffusing action].
Topics: Acetates; Blood; Cortisone; Desoxycorticosterone; Humans; Plasma Volume; Pregnenolone; Thiocyanates | 1952 |
[Effect of cortisone, desoxycorticosterone (alone and with vitamin C), of 21-acetoxypregnenelone, androstendiol dipropionate and hyaluronidase on homoplastic skin grafts in rabbits].
Topics: Androgens; Animals; Ascorbic Acid; Cortisone; Desoxycorticosterone; Hyaluronoglucosaminidase; Lagomorpha; Pregnenolone; Rabbits; Skin Transplantation; Vitamins | 1953 |
Absorption of corticoids and related steroids from subcutaneously implanted pellets in the guinea pig.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Desoxycorticosterone; Guinea Pigs; Pregnenolone; Progesterone; Steroids | 1953 |
Head blood flow, oxygen consumption, and electrical activity in relation to the adrenal cortex.
Topics: Adrenal Cortex; Brain; Desoxycorticosterone; Electroencephalography; Humans; Metabolism; Oxygen Consumption; Pregnenolone | 1953 |
[Clinical, hematological and biochemical study of combined desoxycorticosterone, methylandrostenediol and pregnenolone therapy of a tuberculous patient].
Topics: Androgens; Desoxycorticosterone; Medicine; Methandriol; Pregnenolone; Tuberculosis; Tuberculosis, Pulmonary | 1954 |
Ability of isopregnenolone-21-carboxylates to block renal effects of deoxycorticosterone and aldosterone in rats.
Topics: Aldosterone; Animals; Desoxycorticosterone; Kidney; Mineralocorticoid Receptor Antagonists; Pregnenolone; Rats | 1960 |
Thin-layer chromatography of corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Chromatography; Chromatography, Thin Layer; Cortisone; Desoxycorticosterone; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone | 1962 |
Effects of estradiol, stilbestrol and some alkyl-carbonyl androstanes upon sex differentiation in the medaka. Orvzias latipes.
Topics: Androstanes; Animals; Cortisone; Desoxycorticosterone; Diethylstilbestrol; Estradiol; Oryzias; Pregnenolone; Progesterone; Sex Differentiation; Steroids | 1963 |
STEROIDS IN THE SEMEN OF DOGFISH (SQUALUS ACANTHIAS).
Topics: Aldosterone; Androgens; Androsterone; Animals; Dehydroepiandrosterone; Desoxycorticosterone; Dogfish; Fishes; Pregnenolone; Progesterone; Research; Semen; Squalus acanthias; Steroids | 1963 |
STUDIES IN FETAL METABOLISM. II. METABOLISM OF PROGESTERONE-4-C14 AND PREGNENOLONE-7ALPHA-H3 IN HUMAN FETAL TESTES.
Topics: Adrenal Cortex Hormones; Androgens; Carbon Isotopes; Chromatography; Desoxycorticosterone; Fetus; Humans; Hydroxyprogesterones; Male; Mixed Function Oxygenases; Oxidoreductases; Pregnenolone; Progesterone; Research; Testis; Testosterone; Tritium | 1963 |
ADRENOCORTICAL FUNCTION BIRDS: IN VITRO BIOSYNTHESIS OF RADIOACTIVE CORTICOSTEROIDS FROM PREGNENOLONE-7-H3 AND PROGESTERONE-4-C14 BY ADRENAL GLANDS OF THE DOMESTIC DUCK (ANAS PLATYRHYNCHOS) AND THE CHICKEN (GALLUS DOMESTICUS).
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Chickens; Chromatography; Corticosterone; Desoxycorticosterone; Ducks; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Lactones; Metabolism; Pituitary-Adrenal Function Tests; Poultry; Pregnenolone; Progesterone; Research; Tritium | 1963 |
IN VITRO BIOSYNTHESIS OF CORTICOSTEROID SULFATES BY ADRENAL TUMORAL TISSUE.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Carbon Isotopes; Chromatography; Corticosterone; Cortisone; Dehydroepiandrosterone; Desoxycorticosterone; Hydrocortisone; In Vitro Techniques; Metabolism; Pathology; Pregnenolone; Sulfates; Urine | 1963 |
[CORTICOSTEROIDS IN THE PLACENTA].
Topics: Adrenal Cortex Hormones; Aldosterone; Desoxycorticosterone; Female; Hydroxyprogesterones; Metabolism; Placenta; Placental Hormones; Pregnancy; Pregnenolone; Progesterone | 1964 |
ENZYMIC SYNTHESIS OF STEROID SULPHATES. I. SULPHATION OF STEROIDS BY HUMAN ADRENAL EXTRACTS.
Topics: 17-Ketosteroids; Adenine Nucleotides; Adrenal Glands; Aldosterone; Androsterone; Autoradiography; Chromatography; Cortisone; Dehydroepiandrosterone; Desoxycorticosterone; Estrone; Humans; Hydrocortisone; Metabolism; Pregnenolone; Research; Steroids; Sulfates; Sulfur Isotopes; Testosterone; Tissue Extracts; Transferases | 1964 |
STUDIES ON ESTER SULPHATES. 21. ON SULPHATE CONJUGATION IN FOETAL HUMAN TISSUE EXTRACTS.
Topics: 17-Ketosteroids; Adrenal Glands; Androgens; Androsterone; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estriol; Etiocholanolone; Fetus; Humans; Kidney; Liver; Lung; Metabolism; Phenols; Pregnenolone; Sodium; Spleen; Sulfates; Testosterone; Tissue Extracts | 1964 |
THE EFFECT OF CALCIUM IONS ON CORTICOSTEROIDOGENESIS. CONVERSION OF PREGNENOLONE AND PROGESTERONE TO DEOXYCORTICOSTERONE IN RAT ADRENAL HOMOGENATE FRACTIONS FORTIFIED WITH DIPHOSPHOPYRIDINE NUCLEOTIDE PLUS GLUCOSE 6-PHOSPHATE.
Topics: Adrenal Glands; Calcium; Corticosterone; Desoxycorticosterone; Glucose; Glucose-6-Phosphate; Hexosephosphates; Ions; Metabolism; NAD; NADP; Oxidoreductases; Pharmacology; Phosphates; Pregnenolone; Progesterone; Rats; Research; Tetrazolium Salts | 1964 |
STEROID BIOSYNTHESIS IN THE SEMEN OF DOGFISH (SQUALUS ACANTHIAS).
Topics: Androgens; Animals; Blood Proteins; Cholesterol; Desoxycorticosterone; Dogfish; Humans; Male; Metabolism; Mixed Function Oxygenases; Pregnenolone; Progesterone; Research; Semen; Sharks; Squalus acanthias | 1964 |
STEROID BIOSYNTHESIS IN THE TESTIS OF DOGFISH (SQUALUS ACANTHIAS).
Topics: Animals; Desoxycorticosterone; Dogfish; Humans; Male; Metabolism; Mixed Function Oxygenases; Pregnenolone; Progesterone; Research; Sharks; Spermatozoa; Squalus acanthias; Testis; Testosterone | 1964 |
LOSS OF TWO STEROID 11 BETA-HYDROXYLATING COMPONENTS IN A RAT ADRENOCORTICAL CARCINOMA.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Carcinoma; Desoxycorticosterone; Metabolism; Neoplasms; Neoplasms, Experimental; Pregnenolone; Progesterone; Rats; Research | 1964 |
SYNTHESIS OF STEROIDS IN THE NEWBORN HUMAN ADRENAL IN VITRO.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Aging; Carbon Isotopes; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydrocortisone; In Vitro Techniques; Infant, Newborn; Metabolism; NADP; Pregnenolone; Progesterone; Radiometry; Steroids | 1965 |
STUDIES ON A FEMINIZING HUMAN ADRENAL TUMOR. I. BIOSYNTHESIS IN VITRO OF STEROID HORMONES FROM PREGNENOLONE-4-14C AND PROGESTERONE-4-14C.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Carbon Isotopes; Chromatography; Desoxycorticosterone; Estradiol; Estrogens; Estrone; Humans; Hydroxyprogesterones; In Vitro Techniques; Metabolism; Neoplasms; Pregnenolone; Progesterone; Radiometry; Research; Steroids; Testosterone | 1965 |
OXIDATIVE PHOSPHORYLATION IN LIVER MITOCHONDRIA FROM ADRENALECTOMIZED RATS AND THE RESPONSE TO HORMONES ADDED IN VITRO.
Topics: Adrenalectomy; Aldosterone; Cortisone; Desoxycorticosterone; Epinephrine; In Vitro Techniques; Insulin; Liver; Metabolism; Mitochondria; Mitochondria, Liver; Oxidative Phosphorylation; Pharmacology; Pregnenolone; Research; Transferases; Triamcinolone | 1965 |
Effects of dehydroepiandrosterone on corticosterone release in rat zona fasciculata-reticularis cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cyclic AMP; Dehydroepiandrosterone; Desoxycorticosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Gene Expression; Hydroxycholesterols; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 11-beta-Hydroxylase; Zona Fasciculata; Zona Reticularis | 2003 |
Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats.
Topics: Adrenalectomy; Animals; Brain; Desoxycorticosterone; Ethanol; Male; Orchiectomy; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Steroids | 2004 |
[Effects of 11-desoxycorticosterone and 21-acetoxypregnenolone on granulation tissue].
Topics: Adrenal Cortex Hormones; Desoxycorticosterone; Granulation Tissue; Pregnenolone; Progestins; Wounds and Injuries | 1950 |
[Effect of cortisone, pregnenolone and desoxycorticosterone with 1-ascorbic acid on urinary excretion of nitrogen and sulfur].
Topics: Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Ascorbic Acid; Cortisone; Desoxycorticosterone; Nitrogen; Pregnenolone; Sulfur | 1951 |
Comparative effects of ACTH cortisone, corticosterone, desoxycorticosterone, pregnenolone on growth and development of infant rats.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Biological Phenomena; Corticosterone; Cortisone; Desoxycorticosterone; Growth; Growth and Development; Physiological Phenomena; Pregnenolone; Rats | 1951 |
[Experimental research on the effect of cortisone, desoxycorticosterone and 21 acetoxypregnenolone on hemopoiesis in the rat].
Topics: Animals; Cortisone; Desoxycorticosterone; Hematopoiesis; Pregnenolone; Rats | 1951 |
[Behavior of brain carbohydrates under the influence of desoxycorticosterone in narcotic dose, of cortisone and of pregnenolone in corresponding doses].
Topics: Brain; Carbohydrates; Cortisone; Desoxycorticosterone; Humans; Narcotics; Pregnenolone | 1951 |
Plasma concentrations of anxiolytic neurosteroids in men with normal anxiety scores: a correlation analysis.
Topics: Adult; Anxiety; Desoxycorticosterone; Humans; Male; Pregnanolone; Pregnenolone; Progesterone; Psychiatric Status Rating Scales; Reference Values | 2004 |
The effect of Sutherlandia frutescens on steroidogenesis: confirming indigenous wisdom.
Topics: Adrenal Cortex; Animals; Corticosterone; Desoxycorticosterone; Fabaceae; Immobilization; Injections, Intraperitoneal; Male; Medicine, African Traditional; Plant Extracts; Pregnenolone; Progesterone; Rats; Rats, Wistar; Sheep; Steroid 11-beta-Hydroxylase; Steroid 21-Hydroxylase; Steroids; Stress, Physiological | 2004 |
Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma.
Topics: Adult; Aged; Aged, 80 and over; Animals; Benzodiazepines; Brain Chemistry; Desoxycorticosterone; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Gas Chromatography-Mass Spectrometry; Hepatic Encephalopathy; Humans; In Vitro Techniques; Liver Cirrhosis; Male; Membranes; Middle Aged; Muscimol; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reference Standards | 2006 |
Plasma pregnenolone levels in cynomolgus monkeys following pharmacological challenges of the hypothalamic-pituitary-adrenal axis.
Topics: Adrenocorticotropic Hormone; Animals; Blood-Brain Barrier; Central Nervous System Depressants; Corticotropin-Releasing Hormone; Data Interpretation, Statistical; Desoxycorticosterone; Dexamethasone; Ethanol; Hypothalamo-Hypophyseal System; Macaca fascicularis; Male; Naloxone; Narcotic Antagonists; Pituitary-Adrenal System; Pregnenolone; Self Administration | 2006 |
Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte.
Topics: Androstane-3,17-diol; Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Pregnanediol; Pregnanes; Pregnenolone; Protein Subunits; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; RNA, Messenger; Steroids; Xenopus laevis; Zolpidem | 2006 |
Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Corticosterone; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Gas Chromatography-Mass Spectrometry; Hippocampus; Male; Olanzapine; Pregnanolone; Pregnenolone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 2006 |
Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells.
Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Acetone; Adrenocorticotropic Hormone; Animals; Coix; Colforsin; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Hydroxycholesterols; Phosphoproteins; Plant Extracts; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Zona Fasciculata; Zona Reticularis | 2006 |
Acute effects of neurosteroids in a rodent model of primary paroxysmal dystonia.
Topics: Animals; Animals, Genetically Modified; Cricetinae; Dehydroepiandrosterone; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Mesocricetus; Pregnanolone; Pregnenolone | 2007 |
Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjects.
Topics: Adult; Alcohol-Related Disorders; Analysis of Variance; Animals; Case-Control Studies; Corticotropin-Releasing Hormone; Cosyntropin; Desoxycorticosterone; Dexamethasone; Drug Synergism; Feedback, Physiological; Hormones; Humans; Hypothalamo-Hypophyseal System; Male; Matched-Pair Analysis; Middle Aged; Naloxone; Narcotic Antagonists; Pituitary-Adrenal System; Pregnenolone; Reference Values; Sheep; Stimulation, Chemical; Tobacco Use Disorder | 2008 |
Influence of epipregnanolone on the modulation of rapid tolerance to ethanol by neurosteroids.
Topics: Analysis of Variance; Anesthetics; Animals; Body Temperature; Central Nervous System Depressants; Desoxycorticosterone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Drug Tolerance; Ethanol; Hypothermia; Male; Mice; Motor Activity; Pregnanolone; Pregnenolone | 2007 |
Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy.
Topics: Adult; Anticonvulsants; Body Mass Index; Dehydroepiandrosterone; Desoxycorticosterone; Electroencephalography; Epilepsy; Estradiol; Female; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Premenstrual Syndrome; Progesterone; Receptors, GABA | 2008 |
Real-time analysis of gene regulation by glucocorticoid hormones.
Topics: Animals; Cells, Cultured; Desoxycorticosterone; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucocorticoids; Interleukin-6; Pregnenolone; Rats; Tumor Necrosis Factor-alpha | 2008 |
Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Brain; Brain Chemistry; Desoxycorticosterone; Hepatic Encephalopathy; Humans; Indomethacin; Male; Molecular Structure; Motor Activity; Portacaval Shunt, Surgical; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids | 2008 |
Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats.
Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Corticosterone; Cyclic AMP; Desoxycorticosterone; Drugs, Chinese Herbal; Evodia; Hydroxycholesterols; Indole Alkaloids; Male; Phosphoproteins; Plant Extracts; Pregnenolone; Progesterone; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents; Zona Fasciculata; Zona Reticularis | 2009 |
Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans.
Topics: Adult; Androstane-3,17-diol; Androsterone; Animals; Central Nervous System Depressants; Desoxycorticosterone; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Young Adult | 2010 |
Multiple roles for the first transmembrane domain of GABAA receptor subunits in neurosteroid modulation and spontaneous channel activity.
Topics: Amino Acid Sequence; Animals; Binding Sites; Caenorhabditis elegans Proteins; Desoxycorticosterone; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Ion Channel Gating; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Pregnenolone; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, GABA-A | 2010 |
Effects and mechanisms of nonylphenol on corticosterone release in rat zona fasciculata-reticularis cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Corticosterone; Desoxycorticosterone; Drug Therapy, Combination; Hydroxycholesterols; Male; Phenols; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Zona Fasciculata; Zona Reticularis | 2010 |
Fluconazole inhibits human adrenocortical steroidogenesis in vitro.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cortodoxone; Desoxycorticosterone; Fluconazole; Humans; Hydrocortisone; Ketoconazole; Pregnenolone; Progesterone | 2012 |
2β- and 16β-hydroxylase activity of CYP11A1 and direct stimulatory effect of estrogens on pregnenolone formation.
Topics: Androstenedione; Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Dehydroepiandrosterone; Desoxycorticosterone; Enzyme Assays; Escherichia coli; Estradiol; Estrone; Gene Expression; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Plasmids; Pregnenolone; Recombinant Proteins; Solutions; Substrate Specificity; Testosterone; Transformation, Bacterial | 2015 |
Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.
Topics: Desoxycorticosterone; Glycine; HEK293 Cells; Humans; Hyperekplexia; Models, Molecular; Mutation, Missense; Picrotoxin; Pregnenolone; Receptors, Glycine; Zinc | 2016 |
Usefulness of Simultaneous Measurement of Plasma Steroids, Including Precursors, for the Evaluation of Drug Effects on Adrenal Steroidogenesis in Rats.
Topics: Adrenal Glands; Animals; Body Weight; Corticosterone; Desoxycorticosterone; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Male; Organ Size; Pharmaceutical Preparations; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley | 2017 |
Dose- and time-dependent changes in blood and adrenal levels of multiple steroids in rats after administration of ketoconazole with or without ACTH.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Chromatography, Liquid; Desoxycorticosterone; Dose-Response Relationship, Drug; Ketoconazole; Male; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Time Factors | 2019 |
Plasma concentrations of steroid precursors, steroids, neuroactive steroids, and neurosteroids in healthy neonatal foals from birth to 7 days of age.
Topics: Animals; Animals, Newborn; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Female; Horses; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pregnenolone; Progesterone; Prospective Studies | 2019 |
Longitudinal proneuroactive and neuroactive steroid profiles in medication-free women with, without and at-risk for perinatal depression: A liquid chromatography-tandem mass spectrometry analysis.
Topics: 20-alpha-Dihydroprogesterone; Adult; Anxiety; Chromatography, Liquid; Depression; Depression, Postpartum; Depressive Disorder; Desoxycorticosterone; Female; Humans; Longitudinal Studies; Neurosteroids; Parturition; Pregnancy; Pregnanolone; Pregnenolone; Prenatal Care; Progesterone; Prospective Studies; Risk Factors; Tandem Mass Spectrometry | 2020 |
A preliminary study on the relationship between environmental endocrine disruptors and precocious puberty in girls.
Topics: Case-Control Studies; Child; Corticosterone; Cortodoxone; Desoxycorticosterone; Endocrine Disruptors; Environmental Exposure; Female; Humans; Hydrocortisone; Pregnenolone; Puberty, Precocious | 2022 |
High androgen concentrations in follicular fluid of polycystic ovary syndrome women.
Topics: Adipokines; Androgens; Androstenedione; Apelin; Cohort Studies; Desoxycorticosterone; Female; Follicular Fluid; Humans; Hyperandrogenism; Polycystic Ovary Syndrome; Pregnenolone; Resistin; Retrospective Studies; Testosterone | 2022 |
COVID-19 patients with altered steroid hormone levels are more likely to have higher disease severity.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldosterone; Androstenedione; Androsterone; Chromatography, Liquid; Corticosterone; Cortodoxone; COVID-19; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Estradiol; Estrone; Humans; Hydrocortisone; Pregnenolone; Progesterone; Severity of Illness Index; Tandem Mass Spectrometry | 2022 |