Page last updated: 2024-08-20

pregnenolone and 25-hydroxycholesterol

pregnenolone has been researched along with 25-hydroxycholesterol in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199024 (46.15)18.7374
1990's18 (34.62)18.2507
2000's8 (15.38)29.6817
2010's2 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Begum-Hasan, J; Murphy, BE1
Tuckey, RC1
Izhar, M; Pasmanik, M; Shemesh, M1
Hertelendy, F; Iczkowski, KA1
Johnson, AL; Kowalski, KI; Tilly, JL2
Barnes, HJ; Estabrook, RW; Mathew, PA; Sanders, D; Wada, A; Waterman, MR1
Dasko, LM; Dharmarajan, AM; Ewing, LL; Wallach, EE; Zanagnolo, VL; Zirkin, BR1
Brueggemeier, RW; Gu, Y; Li, PK; Lin, YC; Rikihisa, Y1
Roby, KF; Terranova, PF1
Gu, Y; Lin, YC; Rikihisa, Y1
Hansel, W; Izhar, M; Shalem, Z; Shemesh, M; Shore, LS; Strauss, JF1
Armstrong, DT; Barbe, GJ; Calaresu, FR; Morley, P1
Asem, EK; Hertelendy, F1
Poisner, AM; Tonkowicz, PA1
Lambeth, JD; Xu, XX1
Kandutsch, AA; Taylor, FR1
Georgiou, M; Payne, AH; Perkins, LM1
Lin, YW; Petrino, TR; Wallace, RA1
Marrone, BL; Pulley, DD1
Donaldson, A; Jeffcoate, SL; O'Shaughnessy, PJ; Pearce, S; Sufi, SB1
Carsia, RV; Schwarz, LA; Weber, H1
Jongkind, JF; Molenaar, R; Rommerts, FF; Themmen, AP; van der Molen, HJ; Visser, WJ1
Glover, M; Lambeth, JD; Xu, XX1
Furlanetto, RW; Rodgers, RJ; Veldhuis, JD1
Georgiou, M; Payne, AH; Quinn, PG1
Georgiou, M; Payne, AH1
Holt, JA; Schreiber, JR1
Bakker, GH; Hoogerbrugge, W; Rommerts, FF; van der Molen, HJ1
Hsueh, AJ; Jones, PB1
Degenhart, HJ; Huijmans, JG; Kortleve, DJ1
Javitt, NB; Silavin, SL; Strauss, JF1
Aberhart, DJ; Mason, JI; Murry, BA1
Hemsell, PG; Mason, JI1
Alsema, GJ; Degenhart, HJ; Hoogerbrugge, J1
Cameron, KJ; Kostadinovic, Z; Tuckey, RC2
Cameron, KJ; Tuckey, RC1
Dricu, A; Sjövall, J; Zhang, J1
Vanderhyden, BC1
Norlin, M; Wikvall, K1
Chedrese, PJ; Crellin, NK; Flood, PF; Gillio-Meina, C; Rodway, MR; Swan, CL1
Chiao, YC; Lin, H; Wang, PS; Wang, SW1
Chiao, YC; Cho, WL; Wang, PS1
Chang, LL; Ho, LL; Wang, PS; Wun, WS1
Lin, CS; Lu, CC; Tsai, SC; Wang, PS1
Barrantes, FJ; Wenz, JJ1
Adachi, S; Ijiri, S; Kazeto, Y; Yamauchi, K1
Chang, LL; Chiang, W; Hsia, SM; Hung, CT; Wang, PS; Wun, AW1
Chao, HL; Wang, PS; Wang, SW; Yu, PL1
Alfred Wun, WS; Chang, LL; Wang, PS1
Fraz, S; Lee, AH; Wilson, JY1

Other Studies

52 other study(ies) available for pregnenolone and 25-hydroxycholesterol

ArticleYear
Influence of 19-nortestosterone and androgens on progesterone biosynthetic enzymes in early human placental explants.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 42, Issue:8

    Topics: 3-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Female; Humans; Hydroxycholesterols; Isomerism; Nandrolone; Placenta; Pregnenolone; Progesterone

1992
Cholesterol side-chain cleavage by mitochondria from the human placenta. Studies using hydroxycholesterols as substrates.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 42, Issue:8

    Topics: Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Female; Humans; Hydroxycholesterols; Hydroxylation; Mitochondria; Placenta; Pregnenolone; Rats

1992
Bovine placental progesterone synthesis: comparison of first and second trimesters of gestation.
    Biology of reproduction, 1992, Volume: 46, Issue:5

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenodoxin; Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Female; Hydroxycholesterols; Placenta; Pregnancy; Pregnenolone; Progesterone; RNA, Messenger; Time Factors

1992
Participation of the cytoskeleton in avian granulosa cell steroidogenesis.
    General and comparative endocrinology, 1991, Volume: 82, Issue:3

    Topics: Aminoglutethimide; Androstenols; Animals; Chickens; Colchicine; Colforsin; Cyclic AMP; Cytochalasin B; Cytochalasin D; Cytoskeleton; Female; Granulosa Cells; Hydroxycholesterols; Luteinizing Hormone; Pregnenolone; Progesterone

1991
Cytochrome P450 side-chain cleavage (P450scc) in the hen ovary. I. Regulation of P450scc messenger RNA levels and steroidogenesis in theca cells of developing follicles.
    Biology of reproduction, 1991, Volume: 45, Issue:6

    Topics: Androstenedione; Animals; Blotting, Northern; Blotting, Western; Chickens; Cholesterol Side-Chain Cleavage Enzyme; Cricetinae; Cyclic AMP; Estradiol; Female; Gene Expression Regulation; Hydroxycholesterols; Pregnenolone; Progesterone; Protein Kinases; RNA, Messenger; Steroids; Tetradecanoylphorbol Acetate; Theca Cells

1991
Cytochrome P450 side-chain cleavage (P450scc) in the hen ovary. II. P450scc messenger RNA, immunoreactive protein, and enzyme activity in developing granulosa cells.
    Biology of reproduction, 1991, Volume: 45, Issue:6

    Topics: Animals; Blotting, Northern; Blotting, Western; Chickens; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Cyclic AMP; Enzyme Induction; Female; Follicle Stimulating Hormone; Granulosa Cells; Hydroxycholesterols; Kinetics; Pregnenolone; RNA, Messenger

1991
Expression of functional bovine cholesterol side chain cleavage cytochrome P450 (P450scc) in Escherichia coli.
    Archives of biochemistry and biophysics, 1991, Nov-01, Volume: 290, Issue:2

    Topics: Animals; Base Sequence; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Escherichia coli; Genetic Vectors; Hydroxycholesterols; Mitochondria; Molecular Sequence Data; Plasmids; Pregnenolone; Recombinant Proteins; Substrate Specificity; Transformation, Genetic

1991
Estradiol regulation of the rabbit corpus luteum: in vivo and in vitro studies.
    Endocrinology, 1991, Volume: 128, Issue:6

    Topics: Animals; Corpus Luteum; Drug Implants; Estradiol; Female; Hydroxycholesterols; In Vitro Techniques; Pregnenolone; Progesterone; Rabbits; Time Factors

1991
Gossypolone suppresses progesterone synthesis in bovine luteal cells.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:6

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Female; Gossypol; Hydroxycholesterols; Luteal Cells; Microscopy, Electron; Pregnenolone; Progesterone

1991
Effects of tumor necrosis factor-alpha in vitro on steroidogenesis of healthy and atretic follicles of the rat: theca as a target.
    Endocrinology, 1990, Volume: 126, Issue:5

    Topics: 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Cells, Cultured; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Hydroxycholesterols; Hydroxyprogesterones; Kinetics; Ovarian Follicle; Oxygen; Pregnenolone; Proestrus; Progesterone; Rats; Recombinant Proteins; Steroids; Theca Cells; Tumor Necrosis Factor-alpha

1990
Inhibitory effect of gossypol on steroidogenic pathways in cultured bovine luteal cells.
    Biochemical and biophysical research communications, 1990, Jun-15, Volume: 169, Issue:2

    Topics: Animals; Bucladesine; Cattle; Cells, Cultured; Corpus Luteum; Female; Gossypol; Hydroxycholesterols; Kinetics; Pregnenolone; Progesterone

1990
Control of bovine placental progestin synthesis: calcium dependent steroidogenesis is modulated at the site of the cholesterol side chain cleavage enzyme.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Cyanoketone; Hydroxycholesterols; Placenta; Pregnenolone; Progesterone; Progestins; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate

1988
Insulin enhances luteinizing hormone-stimulated steroidogenesis by porcine theca cells.
    Biology of reproduction, 1989, Volume: 40, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Androstenedione; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Female; Hydroxycholesterols; Insulin; Insulin-Like Growth Factor I; Kinetics; Luteinizing Hormone; Pregnenolone; Progesterone; Relaxin; Swine; Theca Cells

1989
Influence of kaurenol on basal, LH- and forskolin-stimulated progesterone and cAMP production in avian granulosa cells.
    Journal of steroid biochemistry, 1989, Volume: 33, Issue:1

    Topics: Animals; Chickens; Colforsin; Cyclic AMP; Diterpenes; Female; Granulosa Cells; Hydroxycholesterols; In Vitro Techniques; Kinetics; Luteinizing Hormone; Pregnenolone; Progesterone

1989
Evidence for a role for adenosine 3',5'-monophosphate in progesterone secretion by human chorion.
    Endocrinology, 1985, Volume: 116, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cholera Toxin; Chorion; Colforsin; Cyclic AMP; Diterpenes; Female; Humans; Hydroxycholesterols; In Vitro Techniques; Kinetics; Pregnancy; Pregnenolone; Progesterone; Serum Albumin, Bovine

1985
Cholesterol sulfate is a naturally occurring inhibitor of steroidogenesis in isolated rat adrenal mitochondria.
    The Journal of biological chemistry, 1989, May-05, Volume: 264, Issue:13

    Topics: Adrenal Glands; Animals; Biological Transport; Cholesterol; Cholesterol Esters; Cholesterol Side-Chain Cleavage Enzyme; Hydroxycholesterols; In Vitro Techniques; Malates; Male; Mitochondria; Pregnenolone; Rats

1989
Metabolism of 25-hydroxycholesterol in mammalian cell cultures. Side-chain scission to pregnenolone in mouse L929 fibroblasts.
    Journal of lipid research, 1989, Volume: 30, Issue:6

    Topics: Animals; Cells, Cultured; Chromatography, Thin Layer; Cricetinae; Female; Fibroblasts; Gas Chromatography-Mass Spectrometry; Hydroxycholesterols; Hydroxylation; Hydroxymethylglutaryl CoA Reductases; Lung; Mice; Ovary; Pregnenolone; Time Factors

1989
Steroid synthesis-dependent, oxygen-mediated damage of mitochondrial and microsomal cytochrome P-450 enzymes in rat Leydig cell cultures.
    Endocrinology, 1987, Volume: 121, Issue:4

    Topics: Aldehyde-Lyases; Animals; Cells, Cultured; Cyclic AMP; Cytochrome P-450 Enzyme System; Hydroxycholesterols; Leydig Cells; Male; Microsomes; Mitochondria; Oxygen; Pregnenolone; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Estradiol; Steroid 17-alpha-Hydroxylase; Steroids

1987
Steroidogenesis in Fundulus heteroclitus. I. Production of 17 alpha-hydroxy,20 beta-dihydroprogesterone, testosterone, and 17 beta-estradiol by prematurational follicles in vitro.
    General and comparative endocrinology, 1989, Volume: 73, Issue:1

    Topics: 20-alpha-Dihydroprogesterone; Aminoglutethimide; Animals; Culture; Cyprinodontiformes; Dihydrotestosterone; Estradiol; Female; Hydroxycholesterols; Killifishes; Ovarian Follicle; Pregnenolone; Progesterone; Radioimmunoassay; Testosterone

1989
Inhibitory action of epidermal growth factor on progesterone biosynthesis in hen granulosa cells during short term culture: two sites of action.
    Endocrinology, 1986, Volume: 118, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Epidermal Growth Factor; Female; Fibroblast Growth Factors; Granulosa Cells; Hydroxycholesterols; Luteinizing Hormone; Nerve Growth Factors; Ovulation; Pregnenolone; Progesterone

1986
Site of gossypol inhibition of steroidogenesis in purified mouse Leydig cells.
    Journal of steroid biochemistry, 1986, Volume: 25, Issue:5A

    Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Bucladesine; Gossypol; Hydroxycholesterols; Hydroxyprogesterones; Leydig Cells; Luteinizing Hormone; Male; Mice; Pregnenolone; Progesterone; Testosterone

1986
Effect of 3,3'-iminodiproprionitrile (IDPN) on corticosteroidogenesis of isolated adrenocortical cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 184, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Chickens; Corticosterone; Cyclic AMP; Hydroxycholesterols; In Vitro Techniques; Kinetics; Male; Nitriles; Pregnenolone; Rats; Rats, Inbred Strains; Sexual Maturation

1987
Comparison of the cellular composition and steroidogenic properties of preparations of interstitial cells isolated from immature and mature rat testis.
    The Journal of endocrinology, 1987, Volume: 112, Issue:3

    Topics: Aging; Animals; Centrifugation, Density Gradient; Hydroxycholesterols; Leydig Cells; Luteinizing Hormone; Male; Pregnenolone; Rats; Rats, Inbred Strains; Testis

1987
Cholesterol sulfate inhibits adrenal mitochondrial cholesterol side chain cleavage at a site distinct from cytochrome P-450scc. Evidence for an intramitochondrial cholesterol translocator.
    The Journal of biological chemistry, 1987, Jul-05, Volume: 262, Issue:19

    Topics: Adrenal Glands; Aminoglutethimide; Animals; Cattle; Cholesterol; Cholesterol Esters; Cholesterol Side-Chain Cleavage Enzyme; Hydroxycholesterols; Mitochondria; Oxidoreductases; Pregnenolone; Sonication

1987
Synergistic actions of estradiol and the insulin-like growth factor somatomedin-C on swine ovarian (granulosa) cells.
    Endocrinology, 1986, Volume: 119, Issue:2

    Topics: Animals; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Synergism; Estradiol; Female; Granulosa Cells; Hydroxycholesterols; Insulin-Like Growth Factor I; Kinetics; Piperidines; Pregnenolone; Progesterone; Raloxifene Hydrochloride; Somatomedins; Swine

1986
Differences in the control of sterol metabolism between mouse and rat Leydig cells.
    Endocrinology, 1985, Volume: 116, Issue:6

    Topics: Animals; Biological Transport; Cholesterol; Cycloheximide; Hydroxycholesterols; In Vitro Techniques; Leydig Cells; Male; Pregnenolone; Rats; Rats, Inbred Strains; Species Specificity; Sterols

1985
25-Hydroxycholesterol-supported and 8-bromo-adenosine 3',5'-monophosphate-stimulated testosterone production by primary cultures of two populations of rat Leydig cells.
    Endocrinology, 1985, Volume: 117, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Hydroxycholesterols; Leydig Cells; Male; Pregnenolone; Rats; Rats, Inbred Strains; Testosterone

1985
Estrogen regulation of steroidogenesis in rabbit luteal cells.
    Endocrinology, 1985, Volume: 117, Issue:6

    Topics: 20-alpha-Dihydroprogesterone; Aminoglutethimide; Animals; Corpus Luteum; Cytochrome P-450 Enzyme System; Estradiol; Female; Hydroxycholesterols; Pregnenolone; Progesterone; Pseudopregnancy; Rabbits; Superovulation; Time Factors

1985
LH-dependent steroid production and protein phosphorylation in culture of rat tumour Leydig cells.
    Molecular and cellular endocrinology, 1983, Volume: 33, Issue:2-3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Hydroxycholesterols; Leydig Cell Tumor; Luteinizing Hormone; Molecular Weight; Phosphoproteins; Pregnenolone; Protein Kinases; Rats

1983
Pregnenolone biosynthesis by cultured rat granulosa cells: modulation by follicle-stimulating hormone and gonadotropin-releasing hormone.
    Endocrinology, 1982, Volume: 111, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Androstenedione; Animals; Cyanoketone; Cyclic AMP; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Granulosa Cells; Hydroxycholesterols; Pregnenolone; Rats; Rats, Inbred Strains

1982
Conversion of 22S-hydroxy-cholesterol and its effects on the metabolism of other sterols in rat adrenal cells and bovine adrenal mitochondria.
    Acta endocrinologica, 1982, Volume: 100, Issue:4

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Binding Sites; Cattle; Cells, Cultured; Cholesterol; Chromatography, Gas; Corticosterone; Cytochrome P-450 Enzyme System; Hydroxycholesterols; Male; Mitochondria; Pregnenolone; Rats; Rats, Inbred Strains

1982
Reevaluation of the effects of cytochalasins on steroidogenesis: studies on hamster granulosa cells.
    Endocrinology, 1984, Volume: 115, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Aromatase; Caprylates; Cricetinae; Cytochalasin B; Cytochalasin D; Cytochalasins; Estrogens; Female; Granulosa Cells; Hydroxycholesterols; Luteinizing Hormone; Mesocricetus; Pregnenolone; Progesterone

1984
The synthesis and metabolism of [6-3H]-25-hydroxycholesterol in rat adrenal tumor cells.
    Journal of steroid biochemistry, 1983, Volume: 18, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Animals; Chemical Phenomena; Chemistry; Hydroxycholesterols; Kinetics; Male; Mitochondria; Neoplasms, Experimental; Pregnenolone; Rats; Rats, Inbred Strains

1983
Cholesterol sulfate metabolism in human fetal adrenal mitochondria.
    Endocrinology, 1982, Volume: 111, Issue:1

    Topics: Adolescent; Adrenal Glands; Adult; Aging; Calcium; Cholesterol; Cholesterol Esters; Female; Fetus; Humans; Hydroxycholesterols; Infant; Male; Mitochondria; Pregnancy; Pregnenolone

1982
Side chain cleavage of hydroxylated sterols by bovine adrenal cortex mitochondria: observation of 25-hydroxylase activity during incubation at pH 7.80.
    Journal of steroid biochemistry, 1980, Volume: 13, Issue:5

    Topics: Adrenal Cortex; Animals; Cattle; Cholestanetriol 26-Monooxygenase; Hydrogen-Ion Concentration; Hydroxycholesterols; Hydroxylation; Mitochondria; Pregnenolone; Steroid Hydroxylases

1980
Cytochrome P-450scc activity and substrate supply in human placental trophoblasts.
    Molecular and cellular endocrinology, 1994, Volume: 105, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cholesterol; Cholesterol Esters; Cholesterol Side-Chain Cleavage Enzyme; Female; Humans; Hydroxycholesterols; Kinetics; Lipoproteins, LDL; Mitochondria; Placenta; Pregnancy; Pregnenolone; Progesterone; Substrate Specificity; Trophoblasts

1994
Cytochrome P-450scc activity and substrate supply in human placental trophoblasts.
    Molecular and cellular endocrinology, 1994, Volume: 105, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cells, Cultured; Cholesterol Esters; Cholesterol Side-Chain Cleavage Enzyme; Female; Humans; Hydroxycholesterols; Lipoproteins, LDL; Mitochondria; Pregnancy; Pregnenolone; Progesterone; Substrate Cycling; Trophoblasts

1994
Catalytic properties of cytochrome P-450scc purified from the human placenta: comparison to bovine cytochrome P-450scc.
    Biochimica et biophysica acta, 1993, May-13, Volume: 1163, Issue:2

    Topics: Adrenal Glands; Adrenodoxin; Animals; Binding Sites; Catalysis; Cattle; Cytochrome P-450 Enzyme System; Humans; Hydroxycholesterols; Phospholipids; Placenta; Polysorbates; Pregnenolone

1993
Studies on the relationships between 7 alpha-hydroxylation and the ability of 25- and 27-hydroxycholesterol to suppress the activity of HMG-CoA reductase.
    Biochimica et biophysica acta, 1997, Feb-18, Volume: 1344, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Cell Line; Cell Line, Transformed; Cholestenones; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dexamethasone; Humans; Hydrocortisone; Hydroxycholesterols; Hydroxylation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metyrapone; Pregnenolone; Steroid Hydroxylases; Tumor Cells, Cultured

1997
Oocyte-secreted factors regulate granulosa cell steroidogenesis.
    Zygote (Cambridge, England), 1996, Volume: 4, Issue:4

    Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Cyanoketone; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Hydroxycholesterols; Oocytes; Pregnenolone; Progesterone; Rats; Steroids; Testosterone

1996
Biochemical characterization of the 7alpha-hydroxylase activities towards 27-hydroxycholesterol and dehydroepiandrosterone in pig liver microsomes.
    Biochimica et biophysica acta, 1998, Feb-23, Volume: 1390, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxycholesterols; Microsomes, Liver; Pregnenolone; Substrate Specificity; Swine

1998
Regulation of steroidogenesis in jc-410, a stable cell line of porcine granulosa origin.
    Molecular and cellular endocrinology, 1999, Feb-25, Volume: 148, Issue:1-2

    Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Cell Line; Cholera Toxin; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Estradiol; Female; Granulosa Cells; Hydroxycholesterols; Kinetics; Pregnenolone; Progesterone; Swine; Transcription, Genetic

1999
Direct effects of propylthiouracil on testosterone secretion in rat testicular interstitial cells.
    British journal of pharmacology, 2000, Volume: 130, Issue:7

    Topics: Animals; Antithyroid Agents; Drug Interactions; Humans; Hydroxycholesterols; Leydig Cells; Luteinizing Hormone; Male; Pituitary Gland, Anterior; Pregnenolone; Propylthiouracil; Rats; Rats, Sprague-Dawley; Testosterone; Thyroxine

2000
Inhibition of testosterone production by propylthiouracil in rat Leydig cells.
    Biology of reproduction, 2002, Volume: 67, Issue:2

    Topics: Animals; Antimetabolites; Blotting, Western; Cell Separation; Cholesterol Side-Chain Cleavage Enzyme; Depression, Chemical; Dihydrotestosterone; Hydroxycholesterols; Leydig Cells; Male; Phosphoproteins; Pregnenolone; Propylthiouracil; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroids; Testosterone

2002
Effects of dehydroepiandrosterone on corticosterone release in rat zona fasciculata-reticularis cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cyclic AMP; Dehydroepiandrosterone; Desoxycorticosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Gene Expression; Hydroxycholesterols; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 11-beta-Hydroxylase; Zona Fasciculata; Zona Reticularis

2003
Antisteroidogenic actions of hydrogen peroxide on rat Leydig cells.
    Journal of cellular biochemistry, 2003, Dec-15, Volume: 90, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androstenedione; Animals; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Hydroxycholesterols; Leydig Cells; Male; Oxidants; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Spermatozoa; Testosterone

2003
Steroid structural requirements for stabilizing or disrupting lipid domains.
    Biochemistry, 2003, Dec-09, Volume: 42, Issue:48

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Diphenylhexatriene; Fluorescence Polarization; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Hydroxycholesterols; Liposomes; Membrane Microdomains; Models, Chemical; Nitrogen Oxides; Phosphatidylcholines; Phospholipids; Pregnenolone; Spectrometry, Fluorescence; Spin Labels; Steroids; Structure-Activity Relationship

2003
Cloning and characterization of a cDNA encoding cholesterol side-chain cleavage cytochrome P450 (CYP11A1): tissue-distribution and changes in the transcript abundance in ovarian tissue of Japanese eel, Anguilla japonica, during artificially induced sexual
    The Journal of steroid biochemistry and molecular biology, 2006, Volume: 99, Issue:2-3

    Topics: 3-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Anguilla; Animals; Chlorocebus aethiops; Cholesterol Side-Chain Cleavage Enzyme; Cloning, Molecular; COS Cells; DNA, Complementary; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Hydroxycholesterols; Molecular Sequence Data; Ovary; Phylogeny; Pregnenolone; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sexual Development; Steroid 17-alpha-Hydroxylase; Transfection

2006
Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Acetone; Adrenocorticotropic Hormone; Animals; Coix; Colforsin; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Hydroxycholesterols; Phosphoproteins; Plant Extracts; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Zona Fasciculata; Zona Reticularis

2006
Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats.
    Journal of cellular biochemistry, 2009, Oct-01, Volume: 108, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Corticosterone; Cyclic AMP; Desoxycorticosterone; Drugs, Chinese Herbal; Evodia; Hydroxycholesterols; Indole Alkaloids; Male; Phosphoproteins; Plant Extracts; Pregnenolone; Progesterone; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents; Zona Fasciculata; Zona Reticularis

2009
Effects and mechanisms of nonylphenol on corticosterone release in rat zona fasciculata-reticularis cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Corticosterone; Desoxycorticosterone; Drug Therapy, Combination; Hydroxycholesterols; Male; Phenols; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Zona Fasciculata; Zona Reticularis

2010
Gemfibrozil and carbamazepine decrease steroid production in zebrafish testes (Danio rerio).
    Aquatic toxicology (Amsterdam, Netherlands), 2018, Volume: 198

    Topics: Animals; Carbamazepine; Cholesterol; Chorionic Gonadotropin; Gemfibrozil; Humans; Hydroxycholesterols; Male; Pregnenolone; Reproduction; Steroids; Testis; Testosterone; Water Pollutants, Chemical; Zebrafish

2018