Page last updated: 2024-08-20

pregnenolone and 20,22-dihydroxycholesterol

pregnenolone has been researched along with 20,22-dihydroxycholesterol in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burstein, S; Gut, M1
Burstein, S; Gut, M; Middleditch, BS1
Cupp, JR; Vickery, LE1
Kamin, H; Tuckey, RC1
Alsema, GJ; Degenhart, HJ; Hoogerbrugge, J1
Cameron, KJ; Tuckey, RC1
Miura, R; Morishima, N; Sugano, S1
Ruan, B; Schroepfer, GJ; Wilson, WK1

Other Studies

8 other study(ies) available for pregnenolone and 20,22-dihydroxycholesterol

ArticleYear
Intermediates in the conversion of cholesterol to pregnenolone: kinetics and mechanism.
    Steroids, 1976, Volume: 28, Issue:1

    Topics: Adrenal Cortex; Animals; Cattle; Cholesterol; Glycols; Hydroxycholesterols; Kinetics; Mitochondria; Oxygen Consumption; Pregnenolone; Time Factors

1976
Mass spectrometric study of the enzymatic conversion of cholesterol to (22R)-22-hydroxycholesterol, (20R,22R)-20,22-dihydroxycholesterol, and pregnenolone, and of (22R)-22-hydroxycholesterol to the lgycol and pregnenolone in bovine adrenocortical preparat
    The Journal of biological chemistry, 1975, Dec-10, Volume: 250, Issue:23

    Topics: Adrenal Cortex; Adrenal Glands; Animals; Cattle; Cholesterol; Hydroxycholesterols; Mass Spectrometry; Mitochondria; Pregnenolone

1975
Adrenodoxin with a COOH-terminal deletion (des 116-128) exhibits enhanced activity.
    The Journal of biological chemistry, 1989, Jan-25, Volume: 264, Issue:3

    Topics: Adrenodoxin; Amino Acid Sequence; Animals; Carboxypeptidases; Cattle; Cholesterol; Cytochrome P-450 Enzyme System; Hydroxycholesterols; Kinetics; Molecular Weight; NADH Dehydrogenase; Peptide Fragments; Pregnenolone; Structure-Activity Relationship; Trypsin

1989
The oxyferro complex of adrenal cytochrome P-450scc. Effect of cholesterol and intermediates on its stability and optical characteristics.
    The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16

    Topics: Adrenal Cortex; Cholesterol; Cytochrome P-450 Enzyme System; Drug Stability; Hydroxycholesterols; Oxidation-Reduction; Oxygen; Pregnenolone; Protein Binding; Spectrophotometry

1982
Side chain cleavage of hydroxylated sterols by bovine adrenal cortex mitochondria: observation of 25-hydroxylase activity during incubation at pH 7.80.
    Journal of steroid biochemistry, 1980, Volume: 13, Issue:5

    Topics: Adrenal Cortex; Animals; Cattle; Cholestanetriol 26-Monooxygenase; Hydrogen-Ion Concentration; Hydroxycholesterols; Hydroxylation; Mitochondria; Pregnenolone; Steroid Hydroxylases

1980
Human placental cholesterol side-chain cleavage: enzymatic synthesis of (22R)-20 alpha,22-dihydroxycholesterol.
    Steroids, 1993, Volume: 58, Issue:5

    Topics: Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Female; Humans; Hydrogen-Ion Concentration; Hydroxycholesterols; Kinetics; Mitochondria; Placenta; Pregnancy; Pregnenolone

1993
Identification of intermediates in the conversion of cholesterol to pregnenolone with a reconstituted cytochrome p-450scc system: accumulation of the intermediate modulated by the adrenodoxin level.
    Journal of biochemistry, 1996, Volume: 120, Issue:4

    Topics: Adrenodoxin; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydroxycholesterols; Magnetic Resonance Spectroscopy; Mass Spectrometry; Osmolar Concentration; Pregnenolone

1996
An improved synthesis of (20R,22R)-cholest-5-ene-3beta,20,22-triol, an intermediate in steroid hormone formation and an activator of nuclear orphan receptor LXR alpha.
    Steroids, 1999, Volume: 64, Issue:6

    Topics: DNA-Binding Proteins; Hydroxycholesterols; Liver X Receptors; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Orphan Nuclear Receptors; Pregnenolone; Receptors, Cytoplasmic and Nuclear

1999