pregnenolone has been researched along with 17-alpha-hydroxypregnenolone in 311 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 258 (82.96) | 18.7374 |
| 1990's | 20 (6.43) | 18.2507 |
| 2000's | 19 (6.11) | 29.6817 |
| 2010's | 10 (3.22) | 24.3611 |
| 2020's | 4 (1.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chapman, D; Jain, AN; Koile, K | 1 |
| Good, AC; Peterson, SJ; Richards, WG | 1 |
| Good, AC; Richards, WG; So, SS | 1 |
| Platt, DE; Silverman, BD | 1 |
| Crippen, GM | 1 |
| Karplus, M; So, SS | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N | 1 |
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Bedrak, E; Chap, Z | 1 |
| Fevold, HR; Slanina, SM; Wilson, PL | 1 |
| Arai, K; Okinaga, S; Sano, Y; Shibusawa, H; Yoshida, N | 1 |
| Antonichev, AV; Aso, T; Cekan, SZ; Diczfalusy, E; Goncharov, NP; Gorlushkin, VM; Taranov, AG | 1 |
| Bertamino, R; Crovato, F; Moretti, G | 1 |
| Bell, JB | 1 |
| Friedrich, E; Schindler, AE | 1 |
| Schindler, AE; Sparke, H | 2 |
| Couch, RA; Doouss, TW; Skinner, SJ | 1 |
| Schindler, AE; Wuchter, J | 1 |
| Leathem, JH; Murono, EP | 1 |
| Abraham, GE; Chakmakjian, ZH | 2 |
| Benagiano, G; de la Torre, B; Diczfalusy, E | 1 |
| Brinkley, HJ; Weiss, JR; Young, EP | 1 |
| Aso, T; Cekan, Z; Diczfalusy, E; Goncharov, N; Pachalia, N | 1 |
| Aso, T; Cekan, Z; Diczfalusy, E; Goncharov, N | 1 |
| Belvedere, PC; Colombo, L | 1 |
| Mori, T | 1 |
| Aedo, AR; Cekan, SZ; Diczfalusy, E; Landgren, BM; Nuñez, M | 1 |
| Eastman, AR; Neville, AM | 1 |
| Diczfalusy, E | 1 |
| de la Torre, B; Diczfalusy, E; Hedman, M | 1 |
| Preslock, JP; Steinberger, E | 3 |
| Den, M; Haruyama, N; Takasaki, T; Uesato, T; Yoshida, T | 1 |
| Fern, EB; Fern, M; Rose, DP | 1 |
| Bonaventura, LM; Cleary, RE; Judd, H; Roth, LM | 1 |
| Abraham, GE; Bossen, EH; Soules, MR | 1 |
| Bator, JM; Baukal, AJ; Catt, KJ; Cigorraga, SB; Dufau, ML; Neubauer, JF; Sorrell, SH | 1 |
| Shimizu, K | 1 |
| Abul-Hajj, YJ; Iverson, R; Kiang, DT | 1 |
| Ehrenfeld, EN; Finkelstein, M; Fleischer, B; Maschler, I; Weidenfeld, J | 1 |
| Burr, IM; Jennings, AS; Liddle, GW; McKenna, TJ | 1 |
| Anderson, DC; Yen, SS | 1 |
| Davajan, V; Goebelsmann, U; Israel, R; Mestman, JH; Mishell, DR; Zachmann, M | 1 |
| Liddle, GW; McKenna, TJ; Miller, RB | 1 |
| Lorber, DL; McKenna, TJ; Rabinowitz, D | 1 |
| Island, DP; Lacroix, A; Liddle, GW; McKenna, TJ; Miller, RB; Nicholson, WE | 1 |
| Andrada, JA; Hoscholan, JC | 1 |
| Abraham, GE; Buster, JE; Chang, RJ; Cousins, LM; Elashoff, RM; Hobel, CJ; Marshall, JR; Preston, DL | 1 |
| Tilbe, KS; Wiebe, JP | 1 |
| Bandy, L; Hochberg, R; Lieberman, S; Ponticorvo, L; Welch, M | 1 |
| Kime, DE | 1 |
| Anderson, NG; Colás, AE; Curet, LB | 1 |
| Bedrak, E; Chap, Z; Sod-Moriah, UA | 1 |
| Colombo, L; Yaron, Z | 1 |
| Chowdhury, AK; Roll, H; Steinberger, E; Tcholakian, RK | 1 |
| Bartke, A; Harris, ME | 1 |
| Abraham, GE | 1 |
| Anderson, AB; Flint, AP; Turnbull, AC | 1 |
| Brummond, HB; Fevold, HR | 1 |
| Akamatsu, T; Chiba, H; Hirose, K; Kamiyama, H; Saito, H; Yanaihara, T | 1 |
| Akwa, Y; Baulieu, EE; Morfin, RF; Robel, P | 1 |
| Arlotto, MP; Barnes, HJ; Waterman, MR | 1 |
| Cooke, GM | 1 |
| Itakura, M; Koide, Y; Kuzuya, N; Matsumara, M; Murayama, Y; Nakamura, S; Okuda, Y; Takuwa, Y; Tomizawa, H; Watanabe, Y | 1 |
| Lorence, MC; Mason, JI; Murry, BA; Trant, JM | 1 |
| Hirato, K; Yanaihara, T | 1 |
| Imataka, H; Inano, H; Kohmoto, K; Suzuki, K; Tamaoki, B | 1 |
| McCarthy, JL; Waterman, MR | 1 |
| De Clerck, D; De Loof, A; Diederik, H; Ollevier, F | 1 |
| Deslypere, JP; Vermeulen, A | 1 |
| Hall, PF; Simpson, ER; Waterman, MR; Zuber, MX | 1 |
| Singh, S; Singh, TP | 1 |
| Claus, M; Schöneshöfer, M | 1 |
| Crabbe, J; Kolanowski, J; Ortega, N | 1 |
| Gunasegaram, R; Kottegoda, SR; Loganath, A; Peh, KL; Ratnam, SS; Thiagaraj, D | 1 |
| Maki, T | 1 |
| Anderson, DC; Davison, B; Frost, J; Lambert, A; Robertson, WR | 1 |
| Chambaz, EM; Cochet, C; Feige, JJ | 1 |
| Byrne, GC; Perry, YS; Winter, JS | 1 |
| Narita, O; Okuyama, S; Takagi, K; Tomoda, Y; Wu, MC | 1 |
| Gower, DB; Kwan, TK; Taylor, NF; Watson, D | 2 |
| Alén, M; Bolton, N; Ruokonen, A; Vihko, R | 1 |
| Benraad, TJ; Hofman, JA; Kloppenborg, PW; Smals, AG; Weusten, JJ | 1 |
| Makino, K; Miura, K; Ojima, M; Okuyama, M; Sasano, N; Yasuda, K | 1 |
| Araki, H; Maruyama, S; Nakayawa, T; Suzuki, T; Yanaihara, T | 1 |
| Hamamoto, I; Hiwatashi, A; Ichikawa, Y | 1 |
| Bedrak, E; Samoiloff, V; Sod-Moriah, UA | 1 |
| Oh, R; Tamaoki, B | 1 |
| Deshpande, N; Yates, J | 1 |
| Katukawa, H; Nakamura, T; Tanabe, Y | 1 |
| Burgett, MJ; Slaunwhite, WR | 1 |
| Oertel, GW; Rindt, W; Weinand, K | 1 |
| Vihko, R | 1 |
| Grant, JK; Griffiths, K; Pierrepoint, CG; Stewart, JS | 1 |
| Bandi, L; Calvin, HI; Cos, JJ; Lieberman, S; Roberts, KD; Weiss, C | 1 |
| Schuetz, AW | 1 |
| Brownie, AC; Hoschoian, JC | 2 |
| Jaffe, RB; Pérez, AE; Perez-Palacios, G | 1 |
| Christie, GA | 1 |
| Ebersohl, C; Oertel, GW; Rindt, W | 1 |
| Chieffi, G; Delrio, G; Di Prisco, CL | 1 |
| Leymarie, P; Savard, K | 1 |
| Givner, ML; Jaffe, RB; Lamont, KG; Pérez-Palacios, G | 1 |
| Cooke, BA | 1 |
| Anderson, JM; McCormick, MH; Neville, AM; Webb, JL | 1 |
| Garcia, O; Green, OC; Hamwi, GJ; Miller, RR | 1 |
| Lisse, K; Schürenkämper, P | 1 |
| Desplanques, D; Grangaud, R; Nicol, M | 1 |
| Anderson, AB; Cameron, EH; Griffiths, K; Jones, D; Jones, T | 1 |
| Bulbrook, RD; Carson, P; Deshpande, N; Doouss, TW; Jensen, V | 1 |
| Huhtaniemi, I; Luukkainen, T; Vihko, R | 1 |
| Eik-Nes, KB; Frankel, AI | 1 |
| Cooke, BA; Cowan, RA; Taylor, PD | 1 |
| Dorfman, RI; Gottfried, H | 1 |
| Jaffe, RB; Lamont, KG; Pérez, AE; Pérez-Palacios, G | 1 |
| Bloch, E; Klein, M; Lew, M | 2 |
| Francis, FE; Kinsella, RA | 1 |
| Carson, P; Deshpande, N; Harley, S | 1 |
| Lanthier, A; Patwardhan, VV | 1 |
| Bicknell, DC; Gower, DB | 1 |
| Cooke, BA; Dobbie, J; Shirley, IM; Taylor, PD | 1 |
| Cooke, BA; Taylor, PD | 1 |
| Braunberger, G; Menzel, P; Oertel, GW; Rindt, W | 1 |
| Troen, P; Yanaihara, T | 1 |
| Furuyama, J; Matsumoto, K; Mizutani, S; Sonoda, T; Takemura, M | 1 |
| Laatikainen, T; Laitinen, EA; Ruokonen, A; Vihko, R | 1 |
| De Kretser, DM; Lording, DW | 1 |
| Falardeau, P; Tan, L; Wang, HM | 1 |
| Affanni, JM; Galli, FE; Irusta, O; Wassermann, GF | 1 |
| Dizzfalusy, E; Jaffe, RB; Pérez-Palacios, G | 1 |
| Huhtaniemi, I; Vihko, R | 1 |
| Nakamura, T; Tanabe, Y | 2 |
| Axelrod, LR; Milewich, L | 1 |
| Gupta, C; Karavolas, HJ | 2 |
| de Bruijn, HW; van der Molen, HJ | 1 |
| Tingari, MD | 1 |
| Basile, C; Cardellini, LB; Lupo Di Prisco, C; Magni, AP; Rocchi, G | 1 |
| Abraham, GE; Buster, JE; Corrales, PC; Kyle, FW; Teller, RC | 1 |
| Kent, J | 1 |
| Davies, IJ; Ryan, KJ | 1 |
| Dyková, H; Stárka, L; Sulcová, J | 1 |
| Huhtaniemi, I | 3 |
| de Longcamp, D; Drosdowsky, M; Lubet, P | 1 |
| Lofts, B; Phillips, JG; Tam, WH; Tsui, HW | 1 |
| Hipkin, LJ | 1 |
| Eechaute, W; Lacroix, E; Leusen, I | 1 |
| Laatikainen, TJ; Nylander, PL; Peltonen, JI | 1 |
| Nice, E; Williams, K | 1 |
| Brophy, PJ; Gower, DB | 1 |
| Jaffe, RB; Payne, AH | 1 |
| Mackay, AM; Neville, AM; Pettigrew, N; Symington, T | 1 |
| Juillard, MT; Malassiné, A | 1 |
| Kadis, B | 1 |
| Briefer, C; Federman, DD; Kliman, B; Rotner, H; Villee, DB | 1 |
| Camacho, AM; Hagen, AA; Trouy, RL; Wilroy, RS | 1 |
| Lauritzen, C; Mitchell, FL; Shackleton, CH | 1 |
| Bhavnani, BR; Solomon, S | 1 |
| Coutts, JR; Macnaughton, MC; Ross, PE; Walker, J | 1 |
| Bransome, ED; Handler, RP | 1 |
| Fevold, HR | 1 |
| Lauritzen, C | 1 |
| Berger, GM | 1 |
| Eik-Nes, KB; van der Molen, HJ | 1 |
| Cheng, SC; Harding, BW | 1 |
| Iglesias, R; Irusta, O; Van Houtte, I; Wassermann, GF | 1 |
| Brown, RD; DiPietro, DL; Liddle, GW; McKenna, TJ; Strott, CA | 1 |
| McKerns, KW; Nordstrand, E | 1 |
| Kao, KY; McGavack, TH; Trout, EC | 1 |
| Bote, V; Chieffi, G; Tramontana, S | 1 |
| Bjersing, L | 1 |
| Fevold, HR; Pfeiffer, EW | 1 |
| Inano, H; Tamaoki, BI | 1 |
| Huseby, RA; Samuels, LT; Uchikawa, T; Zain-ul-Abedin, M | 1 |
| Bedrak, E; Samuels, LT | 1 |
| Gower, DB; Katkov, T | 1 |
| Cardinali, DP; Cuello, AE; Rosner, JM; Tramezzani, JH | 1 |
| Carson, P; Deshpande, N; Jensen, V | 1 |
| Bermúdez, JA; Herrera, J; León, C; Morán, L; Raudales, L | 1 |
| Flickinger, GL; Mikhail, G; Prazak, L; Wu, CH | 1 |
| Vinson, GP; Whitehouse, BJ | 2 |
| Abraham, GE; Buster, JE; Kyle, FW; Marshall, JR | 1 |
| Kolesnikova, GS; Pivnitskiĭ, KK | 1 |
| Dziadkowiec, I; Rembiesa, R | 1 |
| Bandy, L; Lieberman, S; Roberts, KD | 1 |
| Axelrod, LR; Smith, SW | 1 |
| Grangaud, R; Le Treut, A; Nicol, M; Savoure, N | 1 |
| Kurachi, K; Matsumoto, K; Miyazaki, M; Mori, H | 1 |
| Hurst, L; Jayle, MF; Lacassagne, A | 1 |
| Gupta, C; Karavolas, HJ; Meyer, RK | 1 |
| Tam, WH | 1 |
| Billiar, RB; Halla, M; Heinsons, A; Jassani, M; Kline, IT; Little, B; Purdy, RH | 1 |
| Falardeau, P; Tan, L | 1 |
| Bellini Cardellini, L; Chiefei, G; Delrio, G; Lupo di Prisco, C; Polzonetti Magni, A | 1 |
| Hoppen, HO; Schindler, AE; Siekmann, L; Wuchter, J | 1 |
| Coutts, JR; Macnaughton, MC | 1 |
| Albepart, T; Diczfalusy, E; Lowy, J; Pasqualini, JR; Wiqvist, N | 1 |
| Idler, DR; O'Halloran, MJ | 1 |
| Laatikainen, T; Laitinen, EA; Vihko, R | 1 |
| Cameron, EH; Cunningham, D; Griffiths, K | 1 |
| MacAulay, MA; Weliky, I | 1 |
| Dufau, ML; Kliman, B; Villee, DB | 1 |
| Beynon, MA; Cameron, EH; Griffiths, K | 1 |
| Blank, IH; Brauner, GJ; MacFarlane, DJ; Scheuplein, RJ | 1 |
| Boesen, E; Bulbrook, RD; Deshpande, N; Jensen, V | 1 |
| Siemerink, M; van Leusden, HA | 1 |
| Plotz, EJ; Stein, AA; Wiener, M | 1 |
| Cameron, EH; Grant, JK | 1 |
| Vinson, GP | 1 |
| Corcelle-Cerf, F; Kolanowski, J; Lambert, F; Lammerant, J | 1 |
| Kolanowski, J; Lambert, F; Lammerant, J | 1 |
| Fukuchi, S; Ojima, M; Saito, M | 1 |
| Arai, K; Okinaga, S; Sano, Y; Sekiba, K; Shibusawa, H; Yoshida, N | 1 |
| Bedrak, E; Friedlander, M; Kafka, M; Rosenstrauch, A | 1 |
| Nishikawa, T; Strott, CA | 1 |
| Bermúdez, JA; Gómez, S; González Garza, MT; Herrera, J; Montalvo, I; Sotelo, A | 1 |
| Capella-Pavlovsky, M; Castanier, M; Chartier, M; Daffos, F; Forestier, F; Nahoul, K; Scholler, R | 1 |
| Bhatia, K; Mead, RA; Ravindra, R | 1 |
| Gibson, M; Lackritz, R; Schiff, I; Tulchinsky, D | 1 |
| Barbieri, R; Fencl, MD; Schiff, I; Stillman, RJ; Tulchinsky, D | 1 |
| de Peretti, E; Forest, MG; Lecornu, M | 1 |
| Aedo, AR; Diczfalusy, E; Landgren, BM | 1 |
| Deslypere, JP; Rubens, R; Schelfhout, W; Verdonck, L; Vermeulen, A | 1 |
| Buster, JE; Elsner, C; Freeman, A; Fridshal, D; Magyar, D; Nathanielsz, PW | 1 |
| Hemsell, PG; Korte, K; Mason, JI | 1 |
| Kawakura, K; Matsukura, S; Mori, M; Tamaoki, B | 1 |
| Buster, JE; Eliot, J; Elsner, CW; Glatz, T; Magyar, DM; Nathanielsz, PW | 1 |
| Kojima, S; Nakayama, T; Yanaihara, T | 1 |
| Hall, PF; Nakajin, S | 1 |
| Fukuchi, S; Itoh, N; Kusano, Y; Ojima, M; Saitoh, M | 1 |
| MacDonald, PC; Milewich, L; Smith, SL | 1 |
| Marchut, M | 1 |
| Eechaute, W; Vandekerckhove, D; Vanluchene, E | 1 |
| Arai, K; Okinaga, S; Sano, Y | 1 |
| Goncharov, NP; Taranov, AG | 1 |
| Hall, PF; Nakajin, S; Onoda, M | 1 |
| Givner, ML; Jagarinec, N | 1 |
| Kaufmann, SH; Lommer, D; Sinterhauf, K | 1 |
| Hosaka, M; Oshima, H; Troen, P | 1 |
| Kominami, S; Nishida, N; Takemori, S; Yamazaki, T | 1 |
| Kagawa, N; Katagiri, M; Waterman, MR | 1 |
| Acosta, CK; Kim, HK; Rao, PN | 1 |
| Akhtar, M; Akhtar, ME; Lee-Robichaud, P | 1 |
| Bosc, MJ; Nicolle, A | 1 |
| Ponthier, JL; Shackleton, CH; Trant, JM | 1 |
| Hampl, R; Hill, M; Lapcík, O; Lukác, D; Pouzar, V; Stárka, L; Sulcová, J | 1 |
| Luu-The, V; Soucy, P | 1 |
| Azziz, R; Boots, LR; Decanter, C; Dewailly, D; Huerta, R; Knochenhauer, ES | 1 |
| Beaujean, D; Do-Rego, JL; Leprince, J; Luu-The, V; Mensah-Nyagan, AG; Pelletier, G; Tonon, MC; Vaudry, H | 1 |
| Bicíková, M; Hampl, R; Hill, M; Krausová, Z; Tallová, J | 1 |
| Partsch, CJ; Riepe, FG; Sippell, WG; Wonka, S | 1 |
| Belvedere, P; Carnevali, O; Colombo, L; Dalla Valle, L; Vianello, S | 1 |
| Mahler, P; Partsch, CJ; Riepe, FG; Sippell, WG | 1 |
| Ian Mason, J; Lombard, N; Murry, BA; Nicol, M; Swart, AC; Swart, P; van der Merwe, T | 1 |
| Kobayashi, Y; Nakamura, N; Nakano, K; Obayashi, H; Ohta, M; Tagawa, N | 1 |
| Dorner, M; Falk, W; Schölmerich, J; Straub, RH; Vogl, D | 1 |
| Auchus, RJ; LeHoux, JG; Mathieu, AP | 1 |
| Canario, AV; Freitas, AM; Kime, DE; Leatherland, JF; Petkam, R; Raeside, JI; Renaud, RL | 1 |
| DORFMAN, RI; FORCHIELLI, E; THOMAS, PZ | 1 |
| CARTER, AC; LIEBERMAN, S; SOLOMON, S | 1 |
| ENGEL, LL; WELIKY, I | 1 |
| CLARK, AF; SOLOMON, S | 1 |
| CALVIN, HI; LIEBERMAN, S | 1 |
| CHAMBERLAIN, J; THOMAS, GH | 1 |
| EIK-NES, KB; HAGEN, AA | 1 |
| DORFMAN, RI; SHARMA, DC | 1 |
| DECOURCY, C; HIRSCHMANN, H; LEVY, RP; WIELAND, RG; ZALA, AP | 1 |
| DICZFALUSY, E; ERIKSSON, G; JAFFE, R; PION, R; WIQVIST, N | 1 |
| DAVIES, J; RENNIE, P | 1 |
| KILLINGER, DW; SOLOMON, S | 1 |
| LORING, JM; VILLEE, CA | 1 |
| BAILLIE, AH; GRIFFITHS, K | 1 |
| BAILLIE, AH; CAMERON, EH; GRIFFITHS, K; HART, DM | 1 |
| CRAWFORD, JD; KLIMAN, B; MACGILLIVRAY, M; SCULLY, RE; VILLEE, DB | 1 |
| BIRCHALL, K; CATHRO, DM; FORSYTH, CC; MITCHELL, FL | 1 |
| BOMPIANI, A; KAHNT, FW; NEHER, R; ROVERSI, GD | 1 |
| BRUEHL, P; KAISER, E; OERTEL, GW; ZIMMERMANN, W | 1 |
| SCHEDEWIE, H; TAMM, J; VOIGT, KD; VOLKWEIN, U | 1 |
| FERGUSON, MM | 1 |
| AXELROD, LR | 1 |
| HOKFELT, B; LIPSETT, MB | 1 |
| LIEBERMAN, S; ROBERTS, KD; VANDE WIELE, RL | 1 |
| Bicíková, M; Hampl, R; Havlíková, H; Hill, M; Jirák, R; Rípová, D; Tallová, J | 1 |
| Baulieu, EE; Matsunaga, M; Tsutsui, K; Ukena, K | 1 |
| Bunker, AM; Kushnir, MM; Meikle, AW; Owen, WE; Pattison, EG; Roberts, WL; Rockwood, AL | 1 |
| Bunker, AM; Kushnir, MM; Meikle, AW; Owen, WE; Pattison, EG; Phanslkar, AR; Roberts, WL; Rockwood, AL; Sandrock, T; Terry, AH | 1 |
| Aketo, T; Nakagawa, S; Tachikawa, E; Yamato, S; Yamazaki, N | 1 |
| Cloete, SW; Hough, D; Storbeck, K; Swart, AC; Swart, P | 1 |
| Balog, A; Bonacorsi, SJ; Gong, S; Hong, Y; Tian, Y | 1 |
| Denisov, IG; Gregory, MC; Kincaid, JR; Mak, PJ; Sligar, SG | 1 |
| Chung, BC; Weng, JH | 1 |
| Auchus, RJ; Karashima, S; Kasa-Vubu, JZ; Lerario, AM; Nakamura, Y; Rainey, WE; Rege, J; Sasano, H; Smith, JM; White, PC | 1 |
| Becker, HC; Lopez, MF; Miles, MF; Morrow, AL; O'Buckley, TK; Porcu, P; Williams, RW | 1 |
| Auchus, RJ; Avila, NA; Elman, MS; Mallappa, A; Marko, J; Merke, DP; Rao, H; Tsodikov, A; Turcu, AF | 1 |
| Abdelwahab, A; Ahmed, A; Ahmed, H; Hallman, M; Khashana, A; Rämet, M; Saarela, T | 1 |
| Hartmann, MF; Sánchez-Guijo, A; Tiosano, D; Wang, R; Wudy, SA | 1 |
| De Lafollie, J; Hartmann, MF; Heckmann, M; Hübner, S; Ittermann, T; Ruhnau, J; Sunny, D; Wudy, SA | 1 |
| Botrè, F; Bureik, M; Loke, S; Machalz, D; Parr, MK; Stoll, A; Wolber, G | 1 |
| Akıncı, E; Bal, C; Erel, Ö; Eser, F; Güner, R; Hasanoglu, İ; Kalem, AK; Kayaaslan, B; Sezer, S; Yılmaz, G | 1 |
| Babayev, E; Duncan, FE; Shea, LD; Woodruff, TK; Xu, M | 1 |
4 review(s) available for pregnenolone and 17-alpha-hydroxypregnenolone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Studies on steroids in urine of the male newborn.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Arylsulfatases; Dehydroepiandrosterone; Glucuronidase; Humans; Hydrolysis; Hydroxyprogesterones; Infant, Newborn; Male; Pregnanediol; Pregnanes; Pregnanolone; Pregnenolone; Progesterone | 1975 |
[Dehydrogenation and enzymatic isomerization of delta 5-3 beta-hydroxysteroids].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Female; Humans; Isomerases; Lyases; Male; Mixed Function Oxygenases; Ovary; Oxidoreductases; Placenta; Pregnenolone; Rats; Steroids; Testis; Vitamin A | 1970 |
Nongenomic actions of neurosteroid pregnenolone and its metabolites.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Depression; Humans; Microtubules; Neurodegenerative Diseases; Neurotransmitter Agents; Pregnanolone; Pregnenolone | 2016 |
1 trial(s) available for pregnenolone and 17-alpha-hydroxypregnenolone
| Article | Year |
|---|---|
Pregnenolone, 17-OH-pregnenolone, and testosterone in plasma of patients with congenital adrenal hyperplasia.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Hydrocortisone; Hyperplasia; Infant; Male; Pregnanetriol; Pregnenolone; Progesterone Reductase; Steroid Hydroxylases; Testosterone | 1976 |
306 other study(ies) available for pregnenolone and 17-alpha-hydroxypregnenolone
| Article | Year |
|---|---|
Compass: predicting biological activities from molecular surface properties. Performance comparisons on a steroid benchmark.
Topics: Algorithms; Models, Molecular; Models, Statistical; Molecular Conformation; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Surface Properties; Transcortin | 1994 |
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship | 1993 |
Structure-activity relationships from molecular similarity matrices.
Topics: Computer Simulation; Electrochemistry; Models, Molecular; Molecular Structure; Neural Networks, Computer; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Transcortin | 1993 |
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone | 1996 |
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data.
Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin | 1997 |
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 1. Method and validations.
Topics: Algorithms; Models, Chemical; Molecular Structure; Neural Networks, Computer; Protein Binding; Static Electricity; Steroids; Structure-Activity Relationship; Transcortin | 1997 |
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids | 2008 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
In vitro testosterone synthesis by testicular tissue of old mouse: the metabolism of 3beta-hydroxy-5-ene steroids.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Androgens; Androstenediols; Androstenedione; Animals; Dehydroepiandrosterone; Hydroxyprogesterones; Male; Mice; Mice, Inbred C57BL; NADP; Pregnenolone; Progesterone; Testis; Testosterone | 1977 |
ACTH-stimulated rabbit adrenal 17alpha-hydroxylase. Kinetic properties and a comparison with those of 3beta-hydroxysteroid dehydrogenase.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Kinetics; Male; Microsomes; NADP; Pregnenolone; Rabbits; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1978 |
Studies of the human fetal adrenal gland--properties of 17alpha-hydroxylase and C17-C20 lyase in the biosynthesis of dehydroepiandrosterone from pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Dehydroepiandrosterone; Female; Fetus; Humans; Hydrogen-Ion Concentration; Lyases; Microsomes; NADP; Oxidoreductases; Pregnancy; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Steroids; Subcellular Fractions | 1978 |
Effect of stress on the profile of plasma steroids in baboons (Papio hamadryas).
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Animals; Dihydrotestosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Haplorhini; Hydrocortisone; Hydroxyprogesterones; Immobilization; Male; Papio; Pregnenolone; Progesterone; Progestins; Radioimmunoassay; Radioligand Assay; Stress, Physiological; Testosterone | 1979 |
Cutaneous hydroxystereoid dehydrogenases and rat-hair cycle.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Animals; Cytoplasm; Cytoplasmic Granules; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Hair; Histocytochemistry; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Rats; Sebaceous Glands; Skin; Testosterone | 1975 |
Studies of in vitro steroid metabolism by testis tissue from 'complete' and 'incomplete' forms of testicular feminization.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Androgen-Insensitivity Syndrome; Androstane-3,17-diol; Androstenediols; Androstenedione; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Male; Pregnanolone; Pregnenolone; Progesterone; Testis; Testosterone | 1975 |
Steroid metabolism of foetal tissues. I. Metabolism of pregnenolone-4-14C by human foetal ovaries.
Topics: 17-alpha-Hydroxypregnenolone; Age Factors; Androstenedione; Dehydroepiandrosterone; Estradiol; Estrone; Female; Fetus; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Ovarian Cysts; Ovary; Pituitary Gland; Pregnenolone; Progesterone; Testis; Testosterone | 1975 |
Steroids in umbilical cord plasma from normal term deliveries.
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenols; Dehydroepiandrosterone; Estetrol; Estriol; Female; Fetal Blood; Humans; Hydroxyprogesterones; Male; Pregnanediol; Pregnenolone; Progesterone; Steroids | 1975 |
Synthesis of dehydroepiandrosterone and dehydroepiandrosterone sulphate by the human adrenal.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Corticosterone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Sulfates | 1975 |
Method for the quantitation of steroids in umbilical cord plasma.
Topics: 17-alpha-Hydroxypregnenolone; Androstenes; Arylsulfatases; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Estriol; Fetal Blood; Humans; Hydrolysis; Infant, Newborn; Ketosteroids; Pregnanediol; Pregnenolone; Progesterone; Steroids | 1975 |
Ovarian delta-5-3-beta-hydroxysteroid dehydrogenase in aging rats.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Animals; Corpus Luteum; Cricetinae; Dehydroepiandrosterone; Female; Granulosa Cells; Humans; Hydroxysteroid Dehydrogenases; Mice; Ovary; Pregnenolone; Rats; Theca Cells | 1975 |
Peripheral steroid levels in a patient with virilizing adrenal adenoma.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adult; Androstenedione; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids; Testosterone; Virilism | 1975 |
Pathways of testosterone synthesis in decapsulated testes of mice.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Hydroxyprogesterones; Lanosterol; Leydig Cells; Male; Mice; Pregnenolone; Progesterone; Squalene; Stimulation, Chemical; Testis; Testosterone | 1976 |
In vitro steroidogenesis in porcine corpora lutea.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Corpus Luteum; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Progestins; Swine; Testosterone | 1976 |
Hormonal changes during the menstrual cycle of the baboon (Papio hamadryas).
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Adrenal Cortex Hormones; Androgens; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogens; Estrone; Female; Haplorhini; Humans; Hydroxyprogesterones; Menstruation; Papio; Pregnenolone; Progesterone; Progestins; Species Specificity; Testosterone | 1976 |
Plasma levels of unconjugated steroids in male baboons (Papio hamadryas) and rhesus monkeys (Macaca mulatta).
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Gonadal Steroid Hormones; Haplorhini; Humans; Hydroxyprogesterones; Macaca; Macaca mulatta; Male; Middle Aged; Papio; Pregnenolone; Radioimmunoassay; Species Specificity; Testosterone | 1976 |
Steroid biosynthesis by the ovary of the European eel, Anguilla anguilla L., at the silver stage.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androstenedione; Androsterone; Animals; Dehydroepiandrosterone; Eels; Female; Hydroxyprogesterones; Kinetics; Metyrapone; Ovary; Pregnenes; Pregnenolone; Progesterone; Testosterone | 1976 |
Steroid hormone formation in human ovarian follicles in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Ovary; Pregnenolone; Progesterone; Progestins; Testosterone | 1976 |
Studies on the pattern of circulating steroids in the normal menstrual cycle. Circadian variation in theperi-ovulatory period.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Circadian Rhythm; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Menstruation; Pregnenolone; Reference Values; Testosterone | 1977 |
5-ene-3beta-hydroxysteroid dehydrogenase of human and bovine adrenocortical endoplasmic reticulum: solubilization and fractionation.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Cattle; Centrifugation, Density Gradient; Chromatography, Gel; Dehydroepiandrosterone; Endoplasmic Reticulum; Humans; Hydroxysteroid Dehydrogenases; Isoelectric Focusing; Molecular Weight; Pregnenolone | 1977 |
Interrelations between plasma levels of biologically active LH and ovarian and adrenal steroids in the normal menstrual cycle.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Circadian Rhythm; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Luteinizing Hormone; Menstruation; Pregnenolone; Progesterone; Radioimmunoassay | 1977 |
Species differences in steroidogenesis following the in vitro incubation of decapsulated testes.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androstenedione; Animals; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Gonadal Steroid Hormones; Guinea Pigs; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Testis; Testosterone | 1977 |
Substrate specificity for androgen biosynthesis in the primate testis.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Callitrichinae; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Substrate Specificity; Testis; Testosterone | 1978 |
[Simultaneous determination of pregnenolone, 17 alpha-hydroxypregnenolone and dehydroepiandrosterone].
Topics: 17-alpha-Hydroxypregnenolone; Dehydroepiandrosterone; Female; Humans; Infant, Newborn; Pregnancy; Pregnenolone; Radioimmunoassay | 1978 |
Effect of oral contraceptives on plasma androgenic steroids and their precursors.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Androstenedione; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Dehydroepiandrosterone; Female; Humans; Pregnenolone | 1978 |
Androgen, estrogen, and progesterone by a lipid cell tumor of theovary.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovarian Neoplasms; Ovary; Pregnenolone; Progestins; Testosterone; Veins; Virilism | 1978 |
The steroid profile of a virilizing ovarian tumor.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Female; Granulosa Cell Tumor; Hormones; Humans; Hydroxyprogesterones; Leydig Cell Tumor; Neoplasms, Gonadal Tissue; Ovarian Neoplasms; Pregnenolone; Sertoli Cell Tumor; Testosterone; Virilism | 1978 |
Testicular steroidogenesis in the baboon Papio anubis.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; In Vitro Techniques; Male; Papio; Pregnenolone; Progesterone; Testis; Testosterone | 1978 |
Steroid biosynthetic lesions in gonadotropin-desensitized Leydig cells.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Hydroxyprogesterones; Leydig Cells; Male; Pregnenolone; Progesterone; Rats; Steroids; Testosterone | 1979 |
Metabolism of [17-2H]pregnenolone into 5-[17 beta-2H, 17 alpha-18O]androstene-3 beta, 17 alpha-diol and other products by incubation with the microsomal fraction of boar testis under 18O2 atmosphere.
Topics: 17-alpha-Hydroxypregnenolone; Androstadienes; Androstenediol; Androstenediols; Animals; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Male; Microsomes; Oxygen Isotopes; Pregnenolone; Swine; Testis; Time Factors | 1979 |
Metabolism of pregnenolone and progesterone by testicular microsomes of the baboon Papio anubis and the marmoset Saguinus oedipus.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Callitrichinae; Dehydroepiandrosterone; In Vitro Techniques; Male; Microsomes; Papio; Pregnenolone; Progesterone; Testis; Testosterone | 1979 |
Metabolism of pregnenolone by human breast cancer. Evidence for 17 alpha-hydroxylase and 17,20-lyase.
Topics: 17-alpha-Hydroxypregnenolone; Aged; Aldehyde-Lyases; Androstenedione; Breast Neoplasms; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydroxyprogesterones; Menopause; Middle Aged; Pregnenolone; Progesterone; Receptors, Estrogen; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1979 |
Steroidogenesis in a virilizing ovarian tumour.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Cortodoxone; Estradiol; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Ovarian Neoplasms; Ovary; Pregnenolone; Sertoli-Leydig Cell Tumor; Testosterone; Virilism | 1975 |
Effects of estrogens on adrenal 3 beta-hydroxysteroid dehydrogenase in ovariectomized women.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenediols; Androstenedione; Castration; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Pregnenolone; Progesterone; Testosterone | 1976 |
Male pseudohermaphroditism consistent with 17,20-desmolase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hydroxyprogesterones; Luteinizing Hormone; Lyases; Male; Phenotype; Pregnenolone; Progesterone; Testosterone | 1976 |
Plasma pregnenolone and 17-OH-pregnenolone in patients with adrenal tumors, ACTH excess, or idiopathic hirsutism.
Topics: 17-alpha-Hydroxypregnenolone; Adenocarcinoma; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Carcinoma, Bronchogenic; Circadian Rhythm; Cushing Syndrome; Dexamethasone; Female; Hirsutism; Humans; Hydrocortisone; Lung Neoplasms; Male; Menopause; Ovary; Pregnenolone; Thymoma; Thymus Neoplasms | 1977 |
Plasma pregnenolone and 17-OH-pregnenolone in hirsute amenorrhoeic patients.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Amenorrhea; Chorionic Gonadotropin; Dexamethasone; Female; Hirsutism; Humans; Metyrapone; Pregnanetriol; Pregnenolone | 1978 |
ACTH stimulates late steps in cortisol biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cattle; Cortodoxone; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone | 1979 |
Androgen biosynthesis in experimental cryptorchidism.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Cryptorchidism; Dehydroepiandrosterone; Guinea Pigs; Hydroxyprogesterones; Male; Pregnenolone; Testis; Testosterone | 1975 |
Interrelationships of circulating maternal steroid concentrations in third trimester pregnancies. I. C21 steroids: progesterone, 16 alpha-hydroxyprogesterone, 17 alpha-hydroxyprogesterone, 20 alpha-dihydroprogesterone, delta 5-pregnenolone, delta 5-pregne
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Female; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; Pregnancy; Pregnancy Trimester, Third; Pregnenolone; Progesterone; Progestins; Time Factors | 1979 |
De novo synthesis of steroids (from acetate) by isolated rat Sertoli cells.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Animals; Carbon Radioisotopes; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Male; Pregnenolone; Rats; Sertoli Cells | 1979 |
Naturally occurring lipoidal derivatives of 3 beta-hydroxy-5-pregnen-20-one; 3 beta,17 alpha-dihydroxy-5-pregnen-20-one and 3 beta-hydroxy-5-androsten-17-one.
Topics: 17-alpha-Hydroxypregnenolone; Acetic Anhydrides; Adrenal Glands; Androstenols; Animals; Cattle; Chromatography; Lipids; Mass Spectrometry; Pregnenolone | 1979 |
Steroid biosynthesis by the testes of the dogfish Scyliorhinus caniculus.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstane-3,17-diol; Androstenedione; Animals; Dogfish; Glucuronates; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Progestins; Sharks; Sulfuric Acids; Testis; Testosterone | 1978 |
Changes in C21-steroid metabolism by ovine placentas during cortisol administration.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Estradiol; Estrone; Female; Hydrocortisone; Hydroxyprogesterones; Microsomes; Placenta; Pregnancy; Pregnenolone; Progesterone; Sheep; Testosterone | 1978 |
Effect of heat acclimatization on testicular enzymes involved in androgen biosynthesis via the 5-ene pathway.
Topics: 17-alpha-Hydroxypregnenolone; Acclimatization; Androgens; Androstenediols; Animals; Body Weight; Hot Temperature; In Vitro Techniques; Male; Mice; Organ Size; Pregnenolone; Seminal Vesicles; Testis | 1977 |
Steroid 21-hydroxylase activity in the ovary of the snake Storeria dekayi during pregnancy.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Corpus Luteum; Desoxycorticosterone; Female; Hydroxysteroid Dehydrogenases; Lyases; Ovary; Pregnancy; Pregnancy, Animal; Pregnenolone; Progesterone; Snakes; Steroid Hydroxylases; Steroid Isomerases; Testosterone; Time Factors | 1976 |
Effects of C21 steroids on sex accessory organs and testes of mature hypophysectomized rats.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Hydroxyprogesterones; Hypophysectomy; Male; Pregnenolone; Progesterone; Prostate; Rats; Seminal Vesicles; Spermatogenesis; Testis; Testosterone | 1975 |
Maintenance of rate testis fluid testosterone and dihydrotestosterone levels by pregnenolone and other C21 steroids in hypophysectomized rats.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cell Nucleus; Dihydrotestosterone; Hydroxyprogesterones; Hypophysectomy; Male; Pituitary Gland; Pregnenolone; Progesterone; Rats; Testis; Testosterone | 1975 |
Ovarian and adrenal contribuion to peripheral steroids during the menstrual cycle in two hirsute women.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Glands; Adult; Androstenedione; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Luteinizing Hormone; Menstruation; Menstruation Disturbances; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone | 1975 |
Mechanism of action of glucocorticoids in induction of ovine parturition: effect on placental steroid metabolism.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cholesterol Side-Chain Cleavage Enzyme; Dexamethasone; Female; Fetus; Glucocorticoids; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Labor, Induced; Labor, Obstetric; Placenta; Placental Hormones; Pregnancy; Pregnenolone; Progesterone; Sheep | 1975 |
Steroid biosynthesis by adrenal tissue of snowshoe hares (Lepus americanus) collected in a year of peak population density.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Alberta; Animals; In Vitro Techniques; Lagomorpha; Mammals; Population Density; Pregnenolone | 1976 |
Menopause related changes of adrenocortical steroid production.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Cortex Function Tests; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Female; Humans; Menopause; Middle Aged; Pregnenolone | 1992 |
Neurosteroid metabolism. 7 alpha-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Animals; Brain; Dehydroepiandrosterone; Estrogens; Hydroxylation; Kinetics; Male; Microsomes; Mixed Function Oxygenases; Pregnenolone; Rats; Rats, Sprague-Dawley; Substrate Specificity | 1992 |
Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.
Topics: 17-alpha-Hydroxypregnenolone; Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; DNA; Escherichia coli; In Vitro Techniques; Molecular Sequence Data; Pregnenolone; Progesterone; Recombinant Proteins; Spectrum Analysis; Steroid 17-alpha-Hydroxylase | 1991 |
Steroidogenesis in interstitial cells and microsomal fraction of immature pig testes.
Topics: 17-alpha-Hydroxypregnenolone; Aminoglutethimide; Androgens; Androstenes; Animals; Bucladesine; Cholera Toxin; Chorionic Gonadotropin; Dehydroepiandrosterone; Male; Microsomes; Pregnenolone; Swine; Testis | 1991 |
Successful treatment of a metastatic hormone-producing adrenal cancer by a combination of mitotane, tegafur and surgical resection.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Gland Neoplasms; Adult; Aldosterone; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Corticosterone; Heart Neoplasms; Humans; Hydrocortisone; Liver Neoplasms; Lung Neoplasms; Male; Mitotane; Pregnenolone; Tegafur; Testosterone | 1990 |
Human 3 beta-hydroxysteroid dehydrogenase/delta 5----4isomerase from placenta: expression in nonsteroidogenic cells of a protein that catalyzes the dehydrogenation/isomerization of C21 and C19 steroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Androstenedione; Base Sequence; Dehydroepiandrosterone; DNA; Female; Gene Expression; Humans; Hydroxyprogesterones; Immunoblotting; Isomerases; Microsomes; Molecular Sequence Data; Multienzyme Complexes; NAD; Placenta; Pregnancy; Pregnenolone; Progesterone; Progesterone Reductase; Steroid Isomerases; Transfection; Tumor Cells, Cultured | 1990 |
Serum steroid hormone levels in neonates born from the mother with placental sulfatase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Dehydroepiandrosterone; Female; Fetal Blood; Gonadal Steroid Hormones; Humans; Hydrocortisone; Infant, Newborn; Male; Placenta; Pregnancy; Pregnenolone; Sulfatases | 1990 |
Biosynthetic pathways of testosterone and estradiol-17 beta in slices of the embryonic ovary and testis of the chicken (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenedione; Animals; Chick Embryo; Dehydroepiandrosterone; Estradiol; Estrogens; Female; Hydroxyprogesterones; Male; Ovary; Pregnenolone; Testis; Testosterone | 1989 |
Co-induction of 17 alpha-hydroxylase and C-17,20-lyase activities in primary cultures of bovine adrenocortical cells in response to ACTH treatment.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Aldehyde-Lyases; Animals; Bucladesine; Cattle; Cells, Cultured; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Kinetics; Microsomes; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1988 |
Identification of nonecdysteroid steroids in hemolymph of both male and female Astacus leptodactylus (Crustacea) by gas chromatography-mass spectrometry.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cholesterol; Crustacea; Dehydroepiandrosterone; Dihydrotestosterone; Female; Gas Chromatography-Mass Spectrometry; Hemolymph; Hydroxyprogesterones; Hydroxytestosterones; Male; Pregnenolone; Steroids; Testosterone | 1986 |
Intratesticular unconjugated steroids in elderly men.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adult; Aged; Androstane-3,17-diol; Androstenediol; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Reference Values; Steroids; Testis; Testosterone | 1986 |
Effects of adrenocorticotropin on 17 alpha-hydroxylase activity and cytochrome P-450(17 alpha) synthesis in bovine adrenocortical cells.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bucladesine; Cattle; Cells, Cultured; Cytochrome P-450 Enzyme System; Immunologic Techniques; Kinetics; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1985 |
Kinetic studies on the enzymes involved in estrogen biosynthesis and evidence for existence of a single 5-Ene-3beta-hydroxysteroid dehydrogenase complex in the ovary of the freshwater catfish, Clarias batrachus.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Fishes; Kinetics; Ovary; Pregnenolone; Testosterone | 1985 |
Multiple-sites of inhibition by intravenous metyrapone of human adrenal steroidogenesis.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Corticosterone; Cortodoxone; Humans; Hydrocortisone; Hydroxyprogesterones; Infusions, Parenteral; Male; Metyrapone; Pregnenolone; Progesterone | 1985 |
Enhanced 17 alpha-hydroxylation of pregnenolone and increased androgen production by rabbit adrenocortical cells stimulated chronically with corticotropin.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Androgens; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hydroxylation; In Vitro Techniques; Male; Pregnenolone; Rabbits; Stimulation, Chemical | 1986 |
Steroidogenic expression of delta 5-3 beta-hydroxy pathway of androgen biosynthesis by human breast carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; Acetyl Coenzyme A; Adult; Aged; Androgens; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cholesterol; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Middle Aged; Models, Chemical; Pregnenolone | 1986 |
[Age-related changes in secretion of adrenocortical steroid hormones in normal healthy men].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Aging; Cosyntropin; Dehydroepiandrosterone; Dexamethasone; Humans; Injections, Intramuscular; Male; Middle Aged; Pregnenolone; Progesterone; Radioimmunoassay | 1986 |
Effect of adrenocorticotrophin on cortisol and androstenedione secretion from dispersed cells of guinea-pig adrenal zonae fasciculata and reticularis.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; Animals; Body Weight; Bucladesine; Cells, Cultured; Cortodoxone; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Isomerism; Male; Organ Size; Pregnenolone | 1986 |
Type beta transforming growth factor is a potent modulator of differentiated adrenocortical cell functions.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Angiotensin II; Animals; Cattle; DNA Replication; Hydroxyprogesterones; Peptides; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroids; Transforming Growth Factors | 1986 |
Kinetic analysis of adrenal 3 beta-hydroxysteroid dehydrogenase activity during human development.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Glands; Adult; Aging; Child; Dehydroepiandrosterone; Female; Humans; Infant; Kinetics; Male; Microsomes; Middle Aged; NAD; Pregnenolone | 1985 |
[Analytical method of delta 5-3 beta OH steroid sulfates using high performance liquid chromatography and immobilized 3beta-hydroxysteroid dehydrogenase in column form].
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Female; Humans; Pregnenolone | 1985 |
Gas chromatographic-mass spectrometric study of metabolites of C21 and C19 steroids in neonatal porcine testicular microsomes.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androstenediol; Androstenols; Animals; Animals, Newborn; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Hydroxyprogesterones; Male; Microsomes; Pregnanes; Pregnenolone; Progesterone; Swine; Testis | 1985 |
Response of serum testosterone and its precursor steroids, SHBG and CBG to anabolic steroid and testosterone self-administration in man.
Topics: 17-alpha-Hydroxypregnenolone; Anabolic Agents; Androgens; Androstenediol; Androstenedione; Carrier Proteins; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Kinetics; Male; Pregnenolone; Progesterone; Sex Hormone-Binding Globulin; Sports; Testosterone | 1985 |
Early time sequence in pregnenolone metabolism to testosterone in homogenates of human and rat testis.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aged; Animals; Chromatography, High Pressure Liquid; Humans; Hydroxyprogesterones; Kinetics; Male; Middle Aged; NAD; NADP; Pregnenolone; Progesterone; Rats; Testis; Testosterone | 1987 |
An adrenocortical tumor secreting weak mineralocorticoids.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; Adrenal Cortex Neoplasms; Adult; Carcinoma; Corticosterone; Desoxycorticosterone; Female; Humans; Hydroxyprogesterones; Hypertension; Mineralocorticoids; Pregnenolone; Progesterone | 1987 |
[C21-steroid profiles in pregnancy associated with intrauterine growth retardation].
Topics: 17-alpha-Hydroxypregnenolone; Female; Fetal Growth Retardation; Humans; Hydroxyprogesterones; Pregnancy; Pregnancy Trimester, Third; Pregnenolone; Prenatal Diagnosis; Progesterone | 1986 |
Purification and kinetic properties of 3 beta-hydroxysteroid dehydrogenase from bovine adrenocortical microsomes.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Animals; Binding Sites; Binding, Competitive; Cattle; Dihydrotestosterone; Electrophoresis, Polyacrylamide Gel; Isoelectric Point; Kinetics; Microsomes; Molecular Weight; NAD; NADP; Pregnenolone | 1985 |
Metabolism of 3-beta-hydroxy-5-ene steroids by testes of rats acclimatized to a hot environment.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Acclimatization; Androstanes; Androstenedione; Androstenes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Cryptorchidism; Dehydroepiandrosterone; Hot Temperature; Hydroxyprogesterones; In Vitro Techniques; Male; NADP; Pregnenolone; Rats; Testis; Testosterone; Time Factors; Tissue Extracts | 1973 |
In vitro biosynthesis of androgens in canine testes.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Carbon Radioisotopes; Cytosol; Dehydroepiandrosterone; Dogs; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Mitochondria; NAD; NADP; Pregnenolone; Progesterone; Stimulation, Chemical; Testis; Testosterone; Time Factors | 1973 |
Kinetic studies on the enzymes catalysing the conversion of 17alpha-hydroxyprogesterone and dehydroepiandrosterone to androstenedione in the human adrenal gland in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstenedione; Dehydroepiandrosterone; Depression, Chemical; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Kinetics; Microsomes; NAD; NADP; Oxidoreductases; Pregnenolone; Progesterone | 1974 |
Steroidogenesis in vitro by the ovarian tissue of the domestic fowl (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Autoradiography; Carbon Radioisotopes; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hydroxyprogesterones; In Vitro Techniques; NAD; NADP; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone; Time Factors; Tritium | 1974 |
In vitro testosterone synthesis by rat testicular tissue.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Rats; Subcellular Fractions; Testis; Testosterone | 1965 |
[Biological half-life periods of C21-steroids in guinea pigs].
Topics: 17-alpha-Hydroxypregnenolone; Animals; Blood; Dehydroepiandrosterone; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids | 1966 |
Gas chromatographic-mass spectrometric studies on solvolyzable steroids in human peripheral plasma.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androsterone; Bile Acids and Salts; Blood Chemical Analysis; Cholesterol; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Etiocholanolone; Humans; In Vitro Techniques; Pregnenolone; Progesterone; Spectrum Analysis; Steroids; Testosterone | 1966 |
Neutral steroid sulphation and oestrogen biosynthesis in vitro by a feminizing Leydig cell tumour of the testis.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estriol; Humans; Hydroxyprogesterones; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnenolone; Sulfates | 1966 |
Column liquid-liquid partition chromatography of steroidal sulfates.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Cholesterol; Chromatography; Dehydroepiandrosterone; Etiocholanolone; Pregnanediol; Pregnenolone; Steroids; Sterols; Sulfates | 1966 |
Effect of steroids on germinal vesicle of oocytes of the frog (Rana pipiens) in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Aldosterone; Androgens; Animals; Anura; Cell Nucleus; Cholesterol; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Female; Hydrocortisone; In Vitro Techniques; Ovum; Pregnanediol; Pregnenolone; Progesterone; Steroids; Testosterone | 1967 |
Testosterone biosynthesis in monkey testis.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Carbon Isotopes; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone; Tritium | 1967 |
Pathways for androgen biosynthesis in monkey testis.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Testis; Testosterone; Tritium | 1967 |
Conversion of pregnenolone-7-alpha-3H-sulfate to other delta-5-3-beta-hydroxysteroid sulfates by the human fetal adrenal in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; In Vitro Techniques; Perfusion; Pregnancy; Pregnanes; Pregnenolone; Sulfates; Tritium | 1968 |
Distribution of hydroxysteroid dehydrogenases in the placenta of the pig.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Animals; Castration; Dehydroepiandrosterone; Epithelium; Estradiol; Estrogens; Etiocholanolone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Ovary; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Swine; Trophoblasts | 1968 |
[Effect of gonadotropins on the adrenal cortex. II. Incubation of adrenal homogenates from normal and castrated guinea pigs with 7alpha-3H-cholesterol under the influence of serum gonadotropin].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Animals; Cholesterol; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Glucuronates; Glycolipids; Gonadotropins; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Sulfates; Tritium | 1967 |
Sex hormones in the ovaries of the lizard Lacerta sicula.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Lizards; Male; Ovary; Physiology, Comparative; Pregnenolone; Progesterone; Snakes; Spectrophotometry; Testis; Tissue Extracts | 1968 |
Steroid hormone formation in the human ovary. VI. Evidence for two pathways of synthesis of androgens in the stromal compartment.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androstanes; Biotransformation; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Ovary; Pregnancy; Pregnenolone; Progesterone; Spectrophotometry; Testosterone; Tritium | 1968 |
De novo steriod sulfate biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Adrenal Glands; Androgen-Insensitivity Syndrome; Carbon Isotopes; Cholesterol; Chromatography, Paper; Crystallization; Dehydroepiandrosterone; Fetus; Humans; In Vitro Techniques; Male; Pregnanes; Pregnenolone; Sulfates; Testis | 1968 |
Metabolism of (3H) pregnenolone by adrenal glands from newborn anencephalic infants.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androstanes; Anencephaly; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Infant, Newborn; Pregnenolone; Progesterone; Sulfates; Tritium | 1968 |
Steroid biosynthesis in vitro and in tissue culture by adrenal tumours of mice of the CE strain.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Culture Techniques; Dehydroepiandrosterone; Desoxycorticosterone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Mice; Pregnenolone; Rodent Diseases; Steroids; Tritium | 1968 |
Virilizing male pseudohermaphroditism. Association with abnormal testicular function.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Chorionic Gonadotropin; Dehydroepiandrosterone; Disorders of Sex Development; Humans; Hydroxyprogesterones; Hyperplasia; Leydig Cells; Male; Pregnenolone; Progesterone; Testis; Testosterone; Virilism | 1969 |
[In vitro experiments on steroid hormone formation in the corpus luteum, stroma, hilum and follicles of the normal human ovary].
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstanes; Autoradiography; Carbon Isotopes; Chromatography, Thin Layer; Corpus Luteum; Corpus Luteum Hormones; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone | 1968 |
Effect of vitamin A on enzymic conversion of the delta-5-3-beta-hydroxy- into delta-4-3-oxosteroids by adrenals of the rat.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Acids; Adrenal Glands; Age Factors; Androstanes; Animals; Body Weight; Castration; Dehydroepiandrosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Organ Size; Ovary; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Vitamin A; Vitamin A Deficiency; Weaning | 1969 |
Further studies on the relationship between C19- and C21-steroid synthesis in the human adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Breast Neoplasms; Carbon Isotopes; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Testosterone; Transferases; Tritium | 1969 |
Adrenal function in breast cancer: biogenesis of androgens and cortisol by the human adrenal gland in vivo.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aged; Androgens; Androstanes; Androsterone; Breast Neoplasms; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovary; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Tritium | 1970 |
Identification and determination of neutral steroid sulphates in human foetal adrenal and liver tissue.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androstanes; Chromatography, Gas; Dehydroepiandrosterone; Fetus; Gestational Age; Humans; Liver; Pregnanes; Pregnenolone; Progesterone; Tissue Extracts | 1970 |
The metabolism of steroids in the rabbit epididymis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Acetates; Androstanes; Animals; Carbon Isotopes; Chorionic Gonadotropin; Crystallization; Dehydroepiandrosterone; Epididymis; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Mitochondria; Pregnanes; Pregnenolone; Progesterone; Rabbits; Sterols; Testosterone; Tritium | 1970 |
Pathways of dehydroepiandrosterone sulphate biosynthesis in the human foetal adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography, Gas; Dehydroepiandrosterone; Fetus; Humans; In Vitro Techniques; Kinetics; Pregnenolone; Radioisotope Dilution Technique; Spectrum Analysis; Sulfates; Tritium | 1970 |
Steroids of invertebrates. V. The in vitro biosynthesis of steroids by the male-phase ovotestis of the slug (Ariolimax californicus).
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Animals; Biotransformation; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Crustacea; Dehydroepiandrosterone; Female; Gonads; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Insecta; Male; Mollusca; Pregnenolone; Snails; Steroids; Tritium | 1970 |
Pregnenolone and pregnenolone sulfate metabolism by human fetal testes in vitro.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Fetus; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Sulfatases; Sulfates; Testis; Tritium | 1970 |
Studies on the inhibition of fetal androgen formation. Inhibition of testosterone synthesis in rat and rabbit fetal testes with observations on reproductive tract development.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Abnormalities, Drug-Induced; Androstanes; Animals; Carbon Isotopes; Cholestanes; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Depression, Chemical; Female; Fetus; Genitalia, Male; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Hypospadias; In Vitro Techniques; Indenes; Male; Perineum; Pregnancy; Pregnenolone; Pyridines; Rabbits; Rats; Testis; Testosterone; Wolffian Ducts | 1971 |
Steroids and sterols in meconium.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Androsterone; Bile; Chromatography; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Fetus; Glucuronates; Humans; Infant, Newborn; Intestine, Small; Maternal-Fetal Exchange; Meconium; Placenta; Pregnancy; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Sterols; Testosterone | 1971 |
Adrenal biogenesis in vivo of androgens and cortisol in the guinea-pig using a continuous infusion technique.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androgens; Androstanes; Animals; Carbon Isotopes; Dehydroepiandrosterone; Female; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Methods; Pregnenolone; Progesterone; Tritium | 1971 |
The in vitro formation of androstenedione from C 21 steroids by follicles isolated from human ovaries. A time study.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adult; Androstanes; Carbon Isotopes; Crystallization; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Ovarian Follicle; Ovary; Pregnenolone; Progesterone; Time Factors; Tritium | 1971 |
The separation of C19-16-unsaturated steroids from C21 and other C19-steroids by two-dimensional thin-layer chromatography.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstanes; Androsterone; Autoradiography; Chromatography, Thin Layer; Dehydroepiandrosterone; Estrogens; Etiocholanolone; Hydroxyprogesterones; Methods; Pregnenolone; Progestins; Testosterone | 1971 |
Metabolism of pregnenolone and dehydroepiandrosterone by homogenized tissue from the separated zones and whole adrenal glands from newborn anencephalic infants.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenosine Triphosphate; Adrenal Glands; Androstanes; Anencephaly; Dehydroepiandrosterone; Estrogens; Female; Fetus; Humans; Hydroxysteroid Dehydrogenases; Infant, Newborn; Isomerases; Lyases; Male; Mixed Function Oxygenases; Pregnenolone; Sulfates; Sulfurtransferases; Tritium | 1971 |
Site of dehydroepiandrosterone sulphate biosynthesis in the adrenal gland of the previable foetus.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography, Thin Layer; Dehydroepiandrosterone; Fetus; Freezing; Humans; In Vitro Techniques; Male; Pregnenolone; Sulfates; Tritium | 1971 |
[Steroid-hormones in the guinea pig].
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Animals; Body Weight; Chemotherapy, Cancer, Regional Perfusion; Dehydroepiandrosterone; Glucuronates; Guinea Pigs; Half-Life; Hydrocortisone; Kidney; Liver; Liver Circulation; Mononuclear Phagocyte System; Pregnenolone; Progesterone; Sulfates; Sulfoglycosphingolipids; Tritium | 1971 |
Studies of the human testis. I. Biosynthetic pathways for androgen formation in human testicular tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Aged; Androstanes; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis; Testosterone; Time Factors; Tritium | 1972 |
Steroid biosynthesis in vitro by gonadal tissues in true hermaphroditism.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Dehydroepiandrosterone; Disorders of Sex Development; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Ovary; Pregnanes; Pregnenolone; Progesterone; Sterols; Testis; Testosterone; Tritium | 1972 |
Free and sulfate-conjugated neutral steroids in human testis tissue.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Aged; Androstanes; Androsterone; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Humans; Hydroxysteroids; Ketosteroids; Male; Mass Spectrometry; Middle Aged; Pregnanediol; Pregnanes; Pregnenolone; Steroids; Sulfuric Acids; Testis; Testosterone | 1972 |
Comparative ultrastructural and histochemical studies of the interstitial cells of the rat testis during fetal and postnatal development.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cell Nucleolus; Dehydroepiandrosterone; Endoplasmic Reticulum; Golgi Apparatus; Histocytochemistry; Hydroxysteroid Dehydrogenases; Lipids; Male; Microscopy, Electron; Mitochondria; Pregnenolone; Rats; Testis | 1972 |
17 -hydroperoxypregnenes. 3. Studies on their role as possible precursors in the biosynthesis of adrenosteroid hormones.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Aerobiosis; Anaerobiosis; Androstanes; Animals; Cattle; Chloromercuribenzoates; Chromatography, Gas; Dehydroepiandrosterone; Drug Stability; Glucocorticoids; Hot Temperature; Hydroxyprogesterones; Kinetics; Mass Spectrometry; Peroxides; Pregnenolone; Progesterone | 1972 |
Biosynthesis of steroid hormones by testes and ovaries of the peludo, Chaetophractus villosus (Edentata, mammalia).
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Dehydroepiandrosterone; Female; Male; Ovary; Pregnancy; Pregnanes; Pregnenolone; Progesterone; Testis; Xenarthra | 1972 |
Conversion of pregnenolone and pregnenolone sulfate to other steroid sulfates by the human fetus perfused at midgestation.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Carbon Isotopes; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Liver; Perfusion; Pregnancy; Pregnenolone; Sulfates; Tritium | 1972 |
Steroid metabolism in kidney tissue. I. Endogenous neutral steroids in foetal kidneys and studies on their formation.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Buffers; Chromatography; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Hydroxyprogesterones; In Vitro Techniques; Kidney; Mass Spectrometry; Methods; Mixed Function Oxygenases; Oxidoreductases; Pregnancy; Pregnenolone; Progesterone; Steroids; Sulfates; Sulfurtransferases; Time Factors | 1972 |
In vitro steroidogenesis by testes of the chicken (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenes; Animals; Cell Fractionation; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Isomerases; Male; Microsomes; Oxidoreductases; Pregnenolone; Steroid Hydroxylases; Testis; Testosterone | 1972 |
In vitro metabolism of a mixture of (4- 14 C)pregnenolone and (17 - 3 H)pregnenolone by polycystic ovary: pathways of testosterone biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstenes; Carbon Isotopes; Chromatography, Paper; Crystallization; Cysts; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Ovarian Diseases; Ovary; Pregnenolone; Progesterone; Testosterone; Tritium | 1972 |
Adrenal steroid biosynthesis from 4-14C-cholesterol (in vitro) during phenobarbital block of PMS-induced ovulation in immature rats.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Cholesterol; Chorionic Gonadotropin; Chromatography, Gas; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Gonadotropins, Equine; Hydroxyprogesterones; In Vitro Techniques; Ovulation; Phenobarbital; Pregnenolone; Progesterone; Rats | 1973 |
Elimination of tritium from metabolites of (16- 3 H)-pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androstenedione; Animals; Carbon Isotopes; Dehydroepiandrosterone; Hydrolysis; In Vitro Techniques; Male; Pregnenolone; Rabbits; Testis; Testosterone; Tritium | 1973 |
Histochemical localization of 3 - and 17 -hydroxysteroid dehydrogenases in the male reprodutive tract of the domestic fowl (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Animals; Chickens; Dehydroepiandrosterone; Epididymis; Genitalia, Male; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Microscopy; Pregnenolone; Seminal Vesicles; Testis; Vas Deferens | 1973 |
The metabolic fate of pregnenolone-7 - 3 H and pregesterone-4- 14 C in the ovaries and fat bodies of female Triturus cristatus carnifex.
Topics: 17-alpha-Hydroxypregnenolone; Adipose Tissue; Animals; Carbon Isotopes; Castration; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Ovary; Pregnenolone; Progesterone; Seasons; Time Factors; Tritium; Triturus | 1973 |
Radioimmunoassay of plasma pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone under various physiological conditions.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Child; Chromatography; Climacteric; Dehydroepiandrosterone; Female; Humans; Immune Sera; Infant, Newborn; Male; Menstruation; Methods; Pregnancy; Pregnenolone; Puberty; Radioimmunoassay | 1973 |
Some effects of steroids on the immature mouse ovary in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Culture Techniques; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hydroxyprogesterones; Mice; Mitosis; Ovarian Follicle; Ovary; Pregnenolone; Progesterone; Steroids; Stimulation, Chemical; Testosterone; Thymidine; Tritium | 1973 |
Serum steroid levels during the menstrual cycle in a bilaterally adrenalectomized woman.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Gland Diseases; Adrenalectomy; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Menstruation; Ovary; Pregnenolone; Progesterone; Testosterone | 1973 |
Glucocorticoid synthesis from pregnenolone by sheep foetal adrenals in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstenedione; Animals; Chromatography; Corticosterone; Dehydroepiandrosterone; Fetus; Gestational Age; Glucocorticoids; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Sheep | 1973 |
In vitro metabolism of (4-14C) pregnenolone in the ovaries of intact and HPL or HCG treated rats.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Animals; Carbon Radioisotopes; Chorionic Gonadotropin; Chromatography, Paper; Dehydroepiandrosterone; Drug Synergism; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Hypophysectomy; Ovary; Placental Lactogen; Pregnenolone; Progesterone; Rats; Steroids; Testosterone | 1973 |
Endogenous steroid sulphates and glucuronides in the gallbladder bile from early and mid-term human foetuses.
Topics: 17-alpha-Hydroxypregnenolone; Androstenes; Bile; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetus; Gallbladder; Glucuronates; Humans; Mass Spectrometry; Pregnancy; Pregnanediol; Pregnanetriol; Pregnenolone; Steroids; Sulfates | 1973 |
Formation of neutral steroids from endogenous precursors in minced human fetal adrenals in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Cholesterol; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Female; Fetus; Humans; Mass Spectrometry; Pregnancy; Pregnenolone; Progesterone; Steroids; Sulfuric Acids; Time Factors | 1974 |
The in vitro biosynthesis of steroids by the gonad of the mussel (Mytilus edulis).
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Bivalvia; Carbon Radioisotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Gonads; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; Ovary; Oxidation-Reduction; Pregnenolone; Progesterone; Radioimmunoassay; Testis; Testosterone; Tritium | 1974 |
The annual testicular cycle and androgen production in vitro in the masked civet cat, Paguma l. larvata.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Carbon Radioisotopes; Carnivora; Dehydroepiandrosterone; Histocytochemistry; Hydroxyprogesterones; In Vitro Techniques; Lipids; Male; Organ Size; Pregnenolone; Progesterone; Seasons; Spermatogenesis; Testis; Testosterone | 1974 |
Augmentation of the rat uterine weight response to human chorionic gonadotrophin by various steroids.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Androsterone; Animals; Body Weight; Castration; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Organ Size; Ovary; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Testosterone; Uterus | 1974 |
The biosynthesis of estrogens by cow follicles.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Biotransformation; Cattle; Cells, Cultured; Chromatography; Dehydroepiandrosterone; Estrogens; Female; Manometry; Ovarian Follicle; Pregnenolone; Progesterone; Tritium | 1974 |
Effect of maternal intrahepatic cholestasis on fetal steroid metabolism.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Androsterone; Birth Weight; Cholestasis; Dehydroepiandrosterone; Estriol; Female; Fetus; Gestational Age; Humans; Hydroxylation; Male; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications; Pregnanediol; Pregnanetriol; Pregnenolone; Progesterone; Steroids; Umbilical Cord | 1974 |
Simultaneous estimation of pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone by gas-liquid radiochromatography.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenalectomy; Breast Neoplasms; Carbon Radioisotopes; Chromatography, Gas; Dehydroepiandrosterone; Evaluation Studies as Topic; Female; Humans; Methods; Microsomes; Pregnenolone; Tritium | 1974 |
Studies on the inhibition by 5alpha-pregnane-3,20-dione of the biosynthesis of 16-androstenes and dehydroepiandrosterone in boar testis preparations.
Topics: 17-alpha-Hydroxypregnenolone; Androstadienes; Androstenes; Animals; Carbon Radioisotopes; Cell Fractionation; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Drug Stability; Freezing; Kinetics; Male; Microsomes; Oxidoreductases; Pregnenolone; Progesterone; Swine; Testis; Ultracentrifugation | 1974 |
Androgen formation from pregnenolone sulfate by the human fetal ovary.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Androstenedione; Body Weight; Carbon Radioisotopes; Chromatography, Paper; Dehydroepiandrosterone; Female; Gestational Age; Humans; Liver; Ovary; Pregnenolone; Tritium | 1974 |
Tumors of dysgenetic gonads (gonadoblastoma): ultrastructural and steroidogenic aspects.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Androstenes; Basement Membrane; Cell Nucleus; Cytoplasm; Dehydroepiandrosterone; Dysgerminoma; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Testosterone; Turner Syndrome | 1974 |
[Histoenzymology of the ovary of the pregnant and non-pregnant cat: importance of interstitial tissue].
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cats; Corpus Luteum; Dehydroepiandrosterone; Estradiol; Female; Hydroxysteroid Dehydrogenases; Ovary; Pregnancy; Pregnenolone; Progesterone; Succinate Dehydrogenase; Testosterone; Time Factors | 1973 |
Steroid hydroxylations. V. Intracellular location of 16alpha-hydroxylase and its substrate specificity in sow ovary.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Chromatography, Paper; Dehydroepiandrosterone; Female; Hydroxyprogesterones; In Vitro Techniques; Mixed Function Oxygenases; Ovary; Periodic Acid; Pregnenolone; Progesterone; Swine; Testosterone | 1966 |
Androgen synthesis in a patient with virilizing adrenocortical carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Carbon Isotopes; Chromatography; Culture Techniques; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Testosterone | 1967 |
Inhibition of adrenal cortical secretion by amino-glutethimide in dogs.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Chromatography, Paper; Corticosterone; Dehydroepiandrosterone; Depression, Chemical; Desoxycorticosterone; Dogs; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Pyridones; Veins | 1968 |
The effect of exogenous corticotrophin on steroid excretion in the newborn.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androgens; Chemistry, Clinical; Chromatography, Thin Layer; Dehydroepiandrosterone; Dyspepsia; Feeding and Eating Disorders; Humans; Hydrocortisone; Hyperbilirubinemia; Infant, Newborn; Infant, Premature; Laryngitis; Male; Pregnanes; Pregnenolone; Shock; Stimulation, Chemical | 1968 |
Preparation of 16-alpha-hydroxypregnenolone-3-sulfate and a study of its anomalous behavior during hydrolysis.
Topics: 17-alpha-Hydroxypregnenolone; Biotransformation; Chromatography, Paper; Crystallization; Female; Furans; Glucuronidase; Perchlorates; Pregnancy; Pregnanes; Pregnenolone; Solvents; Streptomyces; Sulfatases; Sulfates; Tritium | 1969 |
Steroidogenesis in a case of hydatidiform mole.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Carbon Isotopes; Cholesterol; Female; Humans; Hydatidiform Mole; Hydroxyprogesterones; Ovarian Cysts; Pregnancy; Pregnanetriol; Pregnenolone; Progesterone; Steroids; Thecoma | 1969 |
Guinea pig adrenal 3-beta-hydroxysteroid dehydrogenase: is there more than one enzyme?
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Binding Sites; Cyanides; Guinea Pigs; Hydrocortisone; Hydroxysteroid Dehydrogenases; Ketones; Male; Methandrostenolone; Microsomes; Pregnenolone | 1969 |
The pathways of corticosteroid biosynthesis by homogenates of adrenal tissue from rabbits stimulated with adrenocorticotropin.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Infrared Rays; Male; Pregnanes; Pregnenolone; Rabbits; Spectrophotometry; Stimulation, Chemical; Time Factors; Tritium | 1969 |
Metabolism of progesterone in the newborn.
Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Animals; Chorionic Gonadotropin; Female; Humans; Infant, Newborn; Male; Milk; Milk, Human; Pregnanediol; Pregnanes; Pregnenolone; Progesterone; Stimulation, Chemical | 1970 |
Possible role of cyclic AMP in the short term regulation of adrenal steroidogenesis.
Topics: 17-alpha-Hydroxypregnenolone; Adenine Nucleotides; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Animals; Cholesterol; Corticosterone; Cyclic AMP; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids | 1971 |
Biosynthesis and secretion of steroids by the canine testis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Chorionic Gonadotropin; Cyclic AMP; Dehydroepiandrosterone; Dogs; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone; Tritium | 1971 |
Lowered ovarian conversion of 14C-pregnenolone to progesterone and other metabolites during phenobarbital (PB) block of PMS-induced ovulation in immature rats: inhibition of 3beta-hydroxysteroid dehydrogenation.
Topics: 17-alpha-Hydroxypregnenolone; Age Factors; Animals; Carbon Isotopes; Estrogens, Conjugated (USP); Estrus; Female; Hydrogenation; Hydroxyprogesterones; Hydroxysteroids; Ketones; Ovary; Ovulation; Phenobarbital; Pregnancy; Pregnanes; Pregnenolone; Progesterone; Rats | 1973 |
Substrate-induced difference spectral, electron paramagnetic resonance, and enzymatic properties of cholesterol-depleted mitochondrial cytochrome P-450 of bovine adrenal cortex.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Acetone; Adrenal Glands; Animals; Cattle; Cholesterol; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Drug Resistance, Microbial; Drug Synergism; Electron Spin Resonance Spectroscopy; Electron Transport; Hydroxylation; Iron; Mitochondria; Oxidation-Reduction; Pregnenolone; Spectrophotometry, Ultraviolet; Surface-Active Agents | 1973 |
Steroid biosynthesis by transplantable gonadal tumors of rat.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androstenedione; Animals; Bucladesine; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Granulosa Cell Tumor; Hydroxyprogesterones; Luteinizing Hormone; Male; Neoplasm Transplantation; Ovarian Neoplasms; Pregnenolone; Progesterone; Rats; Spectrophotometry, Ultraviolet; Testicular Neoplasms; Testosterone; Transplantation, Homologous; Tritium | 1973 |
Plasma 17-OH-pregnenolone in normal subjects.
Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Chorionic Gonadotropin; Chromatography, Thin Layer; Circadian Rhythm; Cross Reactions; Dexamethasone; Female; Humans; Immune Sera; Male; Menstruation; Methyltestosterone; Ovary; Pregnenolone; Radioimmunoassay; Testis; Tritium | 1974 |
Stimulation of the rat ovary by gonadotropins and separation of steroids by gas chromatography.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Cholesterol; Chorionic Gonadotropin; Chromatography, Gas; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Follicle Stimulating Hormone; Glucosephosphate Dehydrogenase; Gonadotropins, Equine; Hydroxyprogesterones; In Vitro Techniques; Luteinizing Hormone; NADP; Nandrolone; Ovary; Pregnenolone; Progesterone; Rats; Subcellular Fractions; Testosterone | 1965 |
Conversion of 17-alpha-hydroxypregnenolone to dehydroepiandrosterone by adrenal homogenates of immature and adult guinea pigs.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Aging; Animals; Animals, Newborn; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dehydroepiandrosterone; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; NADP; Pregnenolone; Tritium | 1967 |
Histochemical distribution of some hydroxysteroid dehydrogenases in the placenta, foetal membranes and uterine mucosa of the mouse.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Dehydroepiandrosterone; Endometrium; Estradiol; Extraembryonic Membranes; Female; Histocytochemistry; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Mice; NAD; NADP; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Testosterone | 1968 |
On the morphology and endocrine function of granulosa cells in ovarian follicles and corpora lutea. Biochemical, histochemical, and ultrastructural studies on the porcine ovary with special reference to steroid hormone synthesis.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Carbon Isotopes; Corpus Luteum; Endocrine Glands; Endoplasmic Reticulum; Female; Histocytochemistry; Hydroxysteroid Dehydrogenases; Male; NADP; Ovary; Oxidoreductases; Pregnenolone; Progesterone; Swine; Testosterone; Tritium | 1968 |
Androgen production in vitro by phalarope gonadal tissue homogenates.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Birds; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; NADP; Ovary; Pregnanes; Pregnenolone; Testis; Testosterone; Tritium | 1968 |
Effect of experimental bilateral cryptorchidism on testicular enzymes related to androgen formation.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Cryptorchidism; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Lyases; Male; Microsomes; Mixed Function Oxygenases; Pregnenolone; Progesterone; Radiation Injuries, Experimental; Radionuclide Imaging; Rats; Steroids; Testis; Testosterone | 1968 |
Effect of diethylstilbestrol on enzymes of cryptochid mouse testes of Balb-c mice.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Cryptorchidism; Dehydroepiandrosterone; Depression, Chemical; Diethylstilbestrol; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Leydig Cells; Lyases; Male; Mice; Microsomes; Mixed Function Oxygenases; Pregnenolone; Progesterone; Testis; Testosterone | 1969 |
Steroid biosynthesis by the equine testis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Age Factors; Androstanes; Animals; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Haplorhini; Horses; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Leydig Cells; Lyases; Male; Mice; Mixed Function Oxygenases; NADP; Physiology, Comparative; Pregnenolone; Testis; Testosterone; Tritium | 1969 |
The biosynthesis of androst-16-enes in boar testis tissue.
Topics: 17-alpha-Hydroxypregnenolone; Adenosine Triphosphate; Androstanes; Animals; Carbon Isotopes; Chromatography, Thin Layer; In Vitro Techniques; Male; NADP; Pregnenolone; Swine; Testis; Testosterone; Tritium | 1970 |
Effects of pinealectomy on the testicular function of the adult male duck.
Topics: 17-alpha-Hydroxypregnenolone; Analysis of Variance; Androstanes; Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Ducks; Hydroxyprogesterones; Male; NADP; Organ Size; Pineal Gland; Pregnenolone; Progesterone; Progestins; Seasons; Testis; Testosterone | 1971 |
Some aspects of the control of dehydroepiandrosterone synthesis in the human adrenal gland in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstanols; Carbon Isotopes; Chromatography, Paper; Cyproterone; Dehydroepiandrosterone; Female; Humans; Hydroxylation; In Vitro Techniques; Kinetics; NADP; Pregnenolone; Subcellular Fractions | 1972 |
Pathways for androgen synthesis in vitro by the testes of Japanese quail (Coturnix coturnix japonica).
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androstanes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Coturnix; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Male; NAD; NADP; Pregnenolone; Progesterone; Testis; Testosterone; Tritium | 1972 |
Metabolism of pregnenolone and pregnenolone sulphate in human foetal liver tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Chromatography, Gas; Chromatography, Gel; Chromatography, Thin Layer; Fetus; Gestational Age; Humans; Hydroxylation; Hydroxysteroid Dehydrogenases; Hydroxysteroids; In Vitro Techniques; Ketosteroids; Liver; Mass Spectrometry; Pregnadienes; Pregnenes; Pregnenolone; Sulfur Radioisotopes; Tritium | 1974 |
[Radioimmunoassay of pregnenolone, 17-hydroxypregnenolone and their sulfoconjugated forms].
Topics: 17-alpha-Hydroxypregnenolone; Endocrine Glands; Female; Humans; Hydroxycorticosteroids; Male; Pregnenolone; Radioimmunoassay | 1974 |
Plasma 20alpha-hydroxypregn-4-en-3-one in the normal menstrual cycle.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cross Reactions; Estradiol; Female; Follicle Stimulating Hormone; Humans; Immune Sera; Luteinizing Hormone; Menstruation; Pregnenolone; Progesterone; Radioimmunoassay; Serum Albumin, Bovine; Sheep; Succinates; Tritium | 1974 |
De-novo steroid synthesis in the seminiferous tubule of the adult rat testis.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androstenedione; Animals; Carbon Isotopes; Hydroxyprogesterones; Male; Pregnanediol; Pregnenolone; Progesterone; Rats; Steroids; Testis; Testosterone; Tritium | 1973 |
Serum steroid levels following a large intravenous dose of a steroid sulfate precursor during the second trimester of human pregnancy. II. Pregnenolone sulfate.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Estradiol; Estriol; Female; Fetal Death; Half-Life; Humans; Hydroxyprogesterones; Placenta; Pregnancy; Pregnenolone; Progesterone; Radioimmunoassay; Sulfates | 1974 |
[Identification of the hydroxylated derivatives of pregnenolone synthesized in the adrenal mitochondria of swine].
Topics: 17-alpha-Hydroxypregnenolone; Acetylation; Adrenal Glands; Animals; Carbon Radioisotopes; Chromates; Chromatography, Paper; Colorimetry; Hydrolysis; In Vitro Techniques; Methods; Mitochondria; Oxidation-Reduction; Pregnenolone; Steroids; Swine | 1974 |
Free cell suspensions from rat placental tissue: metabolism of pregnenolone-4-14C and progesterone-4-14C.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Carbon Radioisotopes; Cell Count; Cells, Cultured; Female; Placenta; Pregnenolone; Progesterone | 1974 |
The occurrence and metabolism of 20 alpha-hydroxycholesterol in bovine adrenal preparations.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Adrenal Glands; Animals; Carbon Isotopes; Cattle; Cholestanes; Cholesterol; Chromatography; Crystallization; Esters; Fatty Acids; Methods; Mitochondria; Oxides; Pregnenolone; Radioisotope Dilution Technique; Sterols; Sulfates; Sulfur Isotopes; Tritium; Vibration | 1969 |
Studies on the metabolism of steroid hormones and their precursors by the human placenta at various stages of gestation. 3. In vitro metabolism of 3 beta, 17 alpha-dihydroxy-pregn-5-ene-20-one.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Chromatography, Paper; Female; Gestational Age; Humans; Hydroxyprogesterones; In Vitro Techniques; Lyases; Placenta; Pregnancy; Pregnanes; Pregnenolone; Radioisotope Dilution Technique; Tritium | 1970 |
In vitro steroid synthesis by foetal rabbit adrenals.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Corticosterone; Crystallization; Enzyme Activation; Female; Fetus; Gestational Age; Hydrocortisone; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mixed Function Oxygenases; Pregnancy; Pregnenolone; Progesterone; Rabbits; Radioisotope Dilution Technique; Steroids; Tritium | 1971 |
[Action of C 21 steroids on cancerization of rat liver by para-dimethylaminoazobenzene (DAB)].
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cell Transformation, Neoplastic; Corticosterone; Desoxycorticosterone; Dexamethasone; Dichlorodiphenyldichloroethane; Hydrocortisone; Hydroxyprogesterones; Liver Neoplasms; Liver Regeneration; Male; p-Dimethylaminoazobenzene; Pregnenolone; Progesterone; Rats | 1969 |
Steroid biosynthesis and metabolism during phenobarbital (PB) block of PMS-induced ovulation in immature rats.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Cholesterol; Dihydrotestosterone; Estradiol; Estriol; Estrone; Female; Liver; Ovary; Ovulation; Phenobarbital; Pregnanes; Pregnenolone; Progesterone; Rats; Testosterone; Time Factors | 1972 |
Steroid metabolic pathways in the ovary of the chinchilla (Chinchilla laniger).
Topics: 17-alpha-Hydroxypregnenolone; Animals; Carbon Isotopes; Chinchilla; Corpus Luteum; Estrogens; Female; Gonadal Steroid Hormones; Hydroxylation; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Ovary; Pregnenolone; Progesterone; Tritium | 1972 |
Pregnenolone production in pregnancy.
Topics: 17-alpha-Hydroxypregnenolone; Body Height; Body Weight; Female; Gestational Age; Hematocrit; Humans; In Vitro Techniques; Infant, Newborn; Maternal-Fetal Exchange; Oxidoreductases; Placenta; Pregnancy; Pregnenolone; Progesterone | 1971 |
Studies on the inhibition of fetal androgen formation: testosterone synthesis by fetal and newborn mouse testes in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Animals, Newborn; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Cyanides; Female; Fetus; In Vitro Techniques; Male; Methandrostenolone; Mice; Pregnancy; Pregnenolone; Progesterone; Testis; Testosterone; Tritium | 1971 |
17 -hydroperoxypregnenes. A new concept in steroid hormonogenesis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Aerobiosis; Aspergillus; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Thin Layer; Crystallization; Free Radicals; Hydroxylation; Mass Spectrometry; Models, Chemical; Oxidation-Reduction; Peroxides; Pregnanes; Pregnenolone | 1971 |
Identification and biosynthesis of steroid hormones in the ovary and fat bodies of female Triturus cristatus carnifex.
Topics: 17-alpha-Hydroxypregnenolone; Adipose Tissue; Androstanes; Animals; Carbon Isotopes; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Estrone; Female; Hydroxyprogesterones; Ketosteroids; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone; Triturus | 1971 |
[Determination of C21-steroids in the urine of newborn infants].
Topics: 17-alpha-Hydroxypregnenolone; Chromatography, Gas; Chromatography, Thin Layer; Humans; Hydroxyprogesterones; Infant, Newborn; Pregnanediol; Pregnanes; Pregnenolone; Progesterone | 1971 |
The metabolism of [4-14C]cholesterol in the pre-viable human foetus.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Carbon Isotopes; Cholesterol; Chromatography; Chromatography, Thin Layer; Female; Fetus; Humans; Liver; Perfusion; Pregnancy; Pregnenolone | 1969 |
Studies on the metabolism of corticosteroids in the human foeto-placental unit. 3. Role of 21-hydroxypregnenolone in the biosynthesis of corticosteroids.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Chromatography; Female; Fetus; Gestational Age; Humans; Placenta; Pregnancy; Pregnanes; Pregnenolone; Steroids | 1970 |
Identification and distribution of the Leydig cell homolog in the testis of sexually mature Atlantic salmon (Salmo salar).
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androsterone; Animals; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Pregnenolone; Salmonidae | 1970 |
Secretion of free and sulfate-conjugated neutral steroids by the human testis. Effect of administration of human chorionic gonadotropin.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adult; Androstanes; Chorionic Gonadotropin; Chromatography, Gas; Hernia, Inguinal; Humans; Hydroxyprogesterones; Male; Middle Aged; Oximes; Pregnanes; Pregnenolone; Silicones; Spectrum Analysis; Sterols; Stimulation, Chemical; Sulfates; Testis; Veins | 1971 |
A comparison of the conversion in vitro of pregnenolone sulphate and pregnenolone to steroid hormones by tissue from a clear cell adenoma of the adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adult; Androgens; Carbon Isotopes; Chromatography, Thin Layer; Corticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Sulfates; Testosterone; Tritium | 1968 |
Corticosteroid biosynthesis from pregnenolone and progesterone by human adrenal tissue in vitro. A kinetic study.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adult; Carbon Isotopes; Chromatography, Paper; Corticosterone; Fetus; Humans; Hydrocortisone; In Vitro Techniques; Kinetics; Pregnenolone; Progesterone; Tritium | 1968 |
Metabolism of pregnenolone-7 alpha-3H and progesterone-4-14C in human granulosa cell tumor slices.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Carbon Isotopes; Chromatography; Chromatography, Thin Layer; Countercurrent Distribution; Dydrogesterone; Estrogens; Female; Granulosa Cell Tumor; Humans; Hydroxyprogesterones; In Vitro Techniques; Pregnanes; Pregnenolone; Progesterone; Tritium | 1968 |
Pregnenolone metabolism in an aldosterone secreting tumor of the adrenal and its adjacent adrenal tissue.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Androgens; Chemistry, Clinical; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Hyperaldosteronism; Mixed Function Oxygenases; Pregnenolone; Tritium | 1968 |
The role of progesterone in the biosynthesis of cortisol in human adrenal tissue.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Acetates; Adrenal Glands; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; Humans; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Middle Aged; Pregnenolone; Progesterone; Tritium | 1968 |
Percutaneous absorption of steroids.
Topics: 17-alpha-Hydroxypregnenolone; Administration, Topical; Aldosterone; Anti-Inflammatory Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Corticosterone; Cortisone; Desoxycorticosterone; Diffusion; Estradiol; Estriol; Estrone; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Skin Absorption; Steroids; Testosterone | 1969 |
In-vitro steroidogenesis by an undifferentiated embryonal cell sarcoma of the ovary.
Topics: 17-alpha-Hydroxypregnenolone; Carbon Isotopes; Child; Estradiol; Female; Humans; Hydroxyprogesterones; Mesenchymoma; Ovarian Neoplasms; Pregnenolone; Progesterone; Testosterone; Tissue Extracts; Tritium | 1969 |
Formation of 17alpha-hydroxy-pregnenolone, 17alpha-hydroxy-progesterone and progesterone by hydatidiform moles in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Chromatography, Thin Layer; Estradiol; Estriol; Estrone; Female; Humans; Hydatidiform Mole; Hydroxyprogesterones; In Vitro Techniques; Pregnancy; Pregnanediol; Pregnanes; Pregnanetriol; Pregnenolone; Progesterone; Tritium | 1969 |
Steroid synthesis in cystadenocarcinoma of the ovaries.
Topics: 17-alpha-Hydroxypregnenolone; Adenocarcinoma, Papillary; Cystadenocarcinoma; Female; Humans; Hydroxyprogesterones; Middle Aged; Ovarian Neoplasms; Pregnenolone; Progesterone; Testosterone | 1966 |
Biochemistry of histologically defined zones in the adrenal cortex: cortisol synthesis in the horse.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Carbon Isotopes; Chromatography, Thin Layer; Histocytochemistry; Horses; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Pregnenolone; Progesterone; Tritium | 1967 |
Role of 21-hydroxypregnenolone in the synthesis of corticosterone from pregnenolone by sheep adrenal tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Sheep; Tritium | 1967 |
On the specificity of the inhibitory effect of trilostane and aminoglutethimide on adrenocortical steroidogenesis in guinea pig.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cortodoxone; Dihydrotestosterone; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Male; Pregnenolone; Progesterone | 1984 |
The enhancement of pregnenolone production as the main mechanism of the prolonged stimulatory effect of ACTH on cortisol production by guinea-pig adrenocortical cells.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Dihydrotestosterone; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Male; Pregnenolone; Time Factors | 1984 |
[The effects of o,p'-DDD on human adrenal steroid synthesis].
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Child, Preschool; Cushing Syndrome; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Middle Aged; Mitotane; Pregnenolone | 1984 |
Steroid 16 alpha-hydroxylase from human fetal liver; inhibition by steroids.
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenols; Aryl Hydrocarbon Hydroxylases; Chlormadinone Acetate; Dehydroepiandrosterone; Estradiol; Estrone; Ethinyl Estradiol; Humans; Liver; Mestranol; Norethindrone; Pregnenolone; Progesterone; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1980 |
Testicular steroidogenesis in the camel (Camelus dromedarius) during the mating and the nonmating seasons.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenediols; Androstenedione; Animals; Camelus; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Progesterone; Sexual Behavior, Animal; Steroid Hydroxylases; Testis; Testosterone | 1983 |
Steroid concentrations in the outer and inner zones of the adrenal cortex of the guinea pig.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Androstenedione; Animals; Dehydroepiandrosterone; Guinea Pigs; Male; Pregnenediones; Pregnenes; Pregnenolone; Tissue Distribution | 1984 |
Modifications in the testis steroidogenic pathways in rats fed with cottonseed flour.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androgens; Animals; Cottonseed Oil; Dehydroepiandrosterone; Diet; Gossypol; Hydroxyprogesterones; Male; Mice; Mice, Inbred Strains; Pregnenolone; Rats; Testis; Testosterone | 1984 |
[Fetal hormonology by direct sampling of fetal blood during the 2d trimester of pregnancy. Study of fetal and maternal 5-ene steroid sulfates].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Blood Specimen Collection; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fetal Blood; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Prenatal Diagnosis | 1984 |
Steroid metabolism in corpora lutea of the western spotted skunk (Spilogale putorius latifrons).
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Carnivora; Corpus Luteum; Dehydroepiandrosterone; Embryo Implantation, Delayed; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Mephitidae; Pregnancy; Pregnenolone; Progesterone; Testosterone | 1984 |
Abnormal adrenal responses to adrenocorticotropic hormone in hyperandrogenic women.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; Pregnenolone; Testosterone; Time Factors | 1980 |
Inhibition of adrenal steroidogenesis by danazol in vivo.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenedione; Cortodoxone; Danazol; Dehydroepiandrosterone; Female; Humans; Pregnadienes; Pregnenolone; Progesterone; Steroids; Time Factors | 1980 |
Familial male pseudohermaphroditism due to 17-20-desmolase deficiency. I. In vivo endocrine studies.
Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldehyde-Lyases; Androstenedione; Child; Chorionic Gonadotropin; Dehydroepiandrosterone; Dexamethasone; Disorders of Sex Development; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Karyotyping; Male; Menstruation; Pedigree; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone | 1980 |
Studies on ovarian and adrenal studies at different phases of the menstrual cycle. IV. The effect of dexamethasone suppression and subsequent ACTH stimulation at different phases of the menstrual cycle and following the administration of 150 mg of depot-m
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Delayed-Action Preparations; Dexamethasone; Estradiol; Female; Humans; Hydrocortisone; Luteinizing Hormone; Medroxyprogesterone; Medroxyprogesterone Acetate; Menstruation; Ovary; Pregnenolone; Progesterone; Steroids | 1981 |
Adrenocortical function in old age: response to acute adrenocorticotropin stimulation.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aged; Aging; Androstenedione; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Progesterone | 1982 |
Time trend analysis of plasma unconjugated and sulfoconjugated estrone and 3 beta-delta 5-steroids in fetal and maternal sheep plasma in relation to spontaneous parturition at term.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Dehydroepiandrosterone; Estrogens, Conjugated (USP); Estrone; Female; Fetal Blood; Gestational Age; Labor, Obstetric; Pregnancy; Pregnancy, Animal; Pregnenolone; Progestins; Sheep; Sulfates | 1982 |
Steroidogenesis in dispersed cells of human fetal adrenal.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Cyanoketone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Pituitary Hormones; Pregnenolone; Steroid 17-alpha-Hydroxylase; Tetrahydronaphthalenes | 1983 |
In-vitro synthesis of androgen from pregnenolone in the testes of the goat (Capra hircus) and identification of 5-pregnene-3beta,17alpha,20alpha-triol as an intermediate in the metabolic pathway of pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Animals; Cell-Free System; Dehydroepiandrosterone; Goats; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenes; Pregnenolone; Progesterone; Testis; Testosterone | 1980 |
A combined radioimmunoassay for the measurement of unconjugated and sulfoconjugated pregnenolone, 17 hydroxypregnenolone, dehydroepiandrosterone, and estrone applied to fetal and maternal ovine plasma.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Dehydroepiandrosterone; Estrone; Female; Fetal Blood; Pregnancy; Pregnenolone; Radioimmunoassay; Sheep | 1981 |
Serum steroid levels in children at birth and in early neonatal period.
Topics: 17-alpha-Hydroxypregnenolone; Adaptation, Physiological; Adrenal Cortex; Cortisone; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Infant, Newborn; Pregnenolone; Progesterone; Steroids | 1981 |
Side-chain cleavage of C21 steroids to C19 steroids by testicular microsomal cytochrome P-450: 17alpha-hydroxy C21 steroids as obligatory intermediates.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Hydroxyprogesterones; Male; Microsomes; Pregnenolone; Progesterone; Swine; Testis | 1981 |
Identification of 16-dehydropregnenolone as an intermediate in 16-androstene biosynthesis in neonatal porcine testicular microsomes.
Topics: 17-alpha-Hydroxypregnenolone; Androstenes; Animals; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Male; Microsomes; Pregnenolone; Testis | 1984 |
[Steroid production in nonfunctioning adrenal tumors].
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Female; Hormones; Humans; Male; Middle Aged; Pregnenolone; Progesterone | 1984 |
Nonrespiratory functions of the human lung: in vitro metabolism of tritium-labeled progesterone and pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Chromatography, Thin Layer; Humans; Lung; Male; Middle Aged; Pregnanediones; Pregnenolone; Progesterone; Time Factors; Tritium | 1980 |
Steroid metabolism in pregnant hamster. I. Metabolism of [4-14C] pregnenolone and [4-14C] progesterone by hamster placental tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cricetinae; Female; Hydroxyprogesterones; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Progesterone | 1980 |
Conversion of free 3 beta-hydroxy-5-ene-steroids by incubation with Helix pomatia.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Chromatography, Gas; Helix, Snails; Hydroxycorticosteroids; Pregnanolone; Pregnenolone | 1982 |
Metabolism of [14C]-C21 steroids in the human fetal ovaries.
Topics: 17-alpha-Hydroxypregnenolone; Female; Fetus; Humans; Hydroxyprogesterones; Kinetics; Ovary; Pregnanediones; Pregnenes; Pregnenolone; Progesterone; Progestins; Tissue Distribution | 1982 |
[Characteristics of the relationship between the circadian rhythm of the concentrations of corticosteroids and their precursors in the blood of baboon hamadryas and the initial functional state of the pituitary-adrenal cortex system].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Aldosterone; Animals; Circadian Rhythm; Cortodoxone; Hydrocortisone; Hydroxyprogesterones; Male; Papio; Pituitary-Adrenal System; Pregnenolone; Progesterone | 1981 |
Testicular microsomal cytochrome P-450 for C21 steroid side chain cleavage. Spectral and binding studies.
Topics: 17-alpha-Hydroxypregnenolone; Aldehyde-Lyases; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hydroxyprogesterones; Kinetics; Male; Microsomes; Pregnenolone; Progesterone; Spectrum Analysis; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Swine; Testis | 1981 |
Effect of medrogestone on conversions of pregnenolone and 17 alpha-hydroxypregnenolone in rat testis.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Male; Medrogestone; Pregnadienes; Pregnenolone; Progesterone; Rats; Testis; Testosterone | 1981 |
21-Hydroxylation of pregnenolone by microsomal preparations of rat and human adrenals.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adult; Animals; Crystallization; Humans; Hydroxylation; Microsomes; Pregnenolone; Rats; Solvents | 1980 |
Studies of the human testis. XIV. Properties of C17-C20 lyase.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Aldehyde-Lyases; Androstenediols; Estradiol; Humans; Hydrogen-Ion Concentration; Hydroxyprogesterones; Male; Microsomes; NADP; Pregnenolone; Steroid 17-alpha-Hydroxylase; Temperature; Testis; Testosterone | 1980 |
Incorporation of bovine adrenal 3 beta-hydroxy-5-ene steroid dehydrogenase/delta 5-delta 4 isomerase into phospholipid vesicles.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Animals; Cattle; Centrifugation, Density Gradient; Cholic Acid; Cholic Acids; Chromatography, Gel; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Stability; Kinetics; Liposomes; Microsomes; Multienzyme Complexes; NAD; Phospholipids; Pregnenolone; Progesterone Reductase; Spectrophotometry; Steroid Isomerases | 1995 |
The role of cytochrome b5 in the biosynthesis of androgens by human P450c17.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androgens; Androstenedione; Cell Membrane; Cytochrome P-450 Enzyme System; Cytochromes b5; Dehydroepiandrosterone; Escherichia coli; Humans; Hydroxyprogesterones; Kinetics; Pregnenolone; Progesterone; Recombinant Proteins; Steroid 17-alpha-Hydroxylase | 1995 |
Tetrapropylammonium perruthenate as a mild and efficient oxidant for sensitive steroidal alcohols.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Alcohols; Androstenedione; Cyclic N-Oxides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hydroxyprogesterones; Ketones; Morpholines; Organometallic Compounds; Oxidants; Oxidation-Reduction; Pregnenediones; Pregnenolone; Quaternary Ammonium Compounds; Ruthenium; Steroids | 1993 |
Control of androgen biosynthesis in the human through the interaction of Arg347 and Arg358 of CYP17 with cytochrome b5.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Arginine; Cytochromes b5; Electron Transport; Genital Diseases, Male; Humans; Kinetics; Male; Mutagenesis, Site-Directed; Pregnenolone; Recombinant Proteins; Spectrum Analysis; Steroid 17-alpha-Hydroxylase | 1998 |
Androstenedione and progesterone production in vitro by the inner or the outer theca cells in preovulatory follicles of gonadotropin stimulated calves.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cattle; Cells, Cultured; Chorionic Gonadotropin; Dehydroepiandrosterone; Female; Hydroxycholesterols; Ovarian Follicle; Ovulation; Pregnenolone; Progesterone; Theca Cells; Time Factors | 1998 |
Seasonal changes in the production of two novel and abundant ovarian steroids in the channel catfish (Ictalurus punctatus).
Topics: 17-alpha-Hydroxypregnenolone; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Hydroxysteroids; Ictaluridae; Ovary; Pregnenolone; Progesterone; Seasons; Testosterone | 1998 |
Age relationships and sex differences in serum levels of pregnenolone and 17-hydroxypregnenolone in healthy subjects.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Pregnenolone; Sex Factors; Time Factors | 1999 |
Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Cell Line; Cytochromes b5; Dehydroepiandrosterone; Humans; Kidney; NADPH-Ferrihemoprotein Reductase; Pregnenolone; Recombinant Fusion Proteins; Steroid 17-alpha-Hydroxylase; Transfection | 2000 |
Adrenocortical hyperresponsivity to adrenocorticotropic hormone: a mechanism favoring the normal production of cortisol in 21-hydroxylase-deficient nonclassic adrenal hyperplasia.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Cortodoxone; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydrocortisone; Pregnenolone; Progesterone; Prospective Studies; Steroid 21-Hydroxylase | 2000 |
The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central-type benzodiazepine receptors.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Animals; Carbolines; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Diazepam Binding Inhibitor; Dihydrotestosterone; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hydroxysteroids; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Ligands; Male; Neuroglia; Neurons; Neuropeptides; Peptide Fragments; Pregnenolone; Progesterone; Rana ridibunda; Receptors, GABA-A | 2001 |
Serum concentrations of some neuroactive steroids in women suffering from mixed anxiety-depressive disorder.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Anxiety; Depressive Disorder; Female; Follicular Phase; Humans; Menstrual Cycle; Middle Aged; Osmolar Concentration; Pregnenolone; Steroids | 2000 |
Automated chromatographic system for the simultaneous measurement of plasma pregnenolone and 17-hydroxypregnenolone by radioimmunoassay.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Automation; Child; Chromatography, Ion Exchange; Female; Humans; Male; Pregnenolone; Radioimmunoassay; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 2001 |
Hormonal steroidogenesis in liver and small intestine of the green frog, Rana esculenta L.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenediol; Androstenedione; Animals; Autoradiography; Cholesterol; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Intestine, Small; Liver; Male; Mitochondria, Liver; Pregnenolone; Progesterone; Rana esculenta; Sex Factors | 2001 |
Longitudinal study of plasma pregnenolone and 17-hydroxypregnenolone in full-term and preterm neonates at birth and during the early neonatal period.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Longitudinal Studies; Male; Maternal-Fetal Exchange; Pregnancy; Pregnenolone; Reference Values; Time Factors | 2002 |
Ovine steroid 17alpha-hydroxylase cytochrome P450: characteristics of the hydroxylase and lyase activities of the adrenal cortex enzyme.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Animals; Blotting, Western; Cell Line; Chromatography, High Pressure Liquid; Cytochromes b5; Humans; Microsomes; Pregnenolone; Progesterone; Sheep; Spectrometry, Mass, Electrospray Ionization; Steroid 17-alpha-Hydroxylase; Steroids; Substrate Specificity; Time Factors | 2003 |
Serum concentrations of delta 5-3 beta-hydroxysteroids in type 2 diabetes mellitus.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenediol; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Pregnenolone; Statistics, Nonparametric | 2002 |
Serum levels of pregnenolone and 17-hydroxypregnenolone in patients with rheumatoid arthritis and systemic lupus erythematosus: relation to other adrenal hormones.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adult; Aged; Androstenedione; Arthritis, Rheumatoid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Lupus Erythematosus, Systemic; Male; Middle Aged; Pregnenolone; Progesterone | 2003 |
Molecular dynamics of substrate complexes with hamster cytochrome P450c17 (CYP17): mechanistic approach to understanding substrate binding and activities.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Amino Acid Sequence; Animals; Binding Sites; Computer Simulation; Cricetinae; Isoenzymes; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Substrate Specificity | 2003 |
In vitro metabolism of pregnenolone to 7alpha-hydroxypregnenolone by rainbow trout embryos.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Chromatography, High Pressure Liquid; Embryo, Nonmammalian; Embryonic Development; Female; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Indicators and Reagents; Male; Oncorhynchus mykiss; Oocytes; Ovarian Follicle; Pregnenolone | 2003 |
The reduction in vitro of 17 alpha-hydroxypregnenolone (3 beta, 17 alpha-dihydroxy-delta 5-pregnen-20-one) by rabbit skeletal muscle.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Hydroxycholecalciferols; In Vitro Techniques; Muscle, Skeletal; Muscles; Pregnenolone; Rabbits | 1960 |
The conversion in vivo of 17-alpha-hydroxypregnenolone to dehydroisoandrosterone and other 17-ketosteroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Biological Assay; Dehydroepiandrosterone; Humans; Lipid Metabolism; Pregnenolone | 1960 |
The conversion in vitro of 17-hydroxypregnenolone to cortisol by a human adrenal tumor.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Cortex Neoplasms; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone | 1962 |
Effect of dehydroisoandrosterone on the in vivo conversion of 17Alpha-hydroxypregnenolone to urinary 11-desoxy-17-ketosteroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Dehydroepiandrosterone; Humans; Pregnenolone | 1963 |
EVIDENCE THAT STEROID SULFATES SERVE AS BIOSYNTHETIC INTERMEDIATES. II. IN VITRO CONVERSION OF PREGNENOLONE-3H SULFATE-35S TO 17ALPHA-HYDROXYPREGNENOLONE-3H SULFATE-35S.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Cushing Syndrome; Dehydroepiandrosterone; Humans; In Vitro Techniques; Infrared Rays; Metabolism; Pregnanediol; Pregnenolone; Sulfates; Sulfur Isotopes; Tritium; Urine | 1964 |
CHARACTERIZATION OF 20-OXOSTEROIDS BY GAS CHROMATOGRAPHY.
Topics: 17-alpha-Hydroxypregnenolone; Chromatography; Chromatography, Gas; Hydroxyprogesterones; Ketosteroids; Pregnenolone; Progesterone; Research; Steroids | 1964 |
CONVERSION OF 17-ALPHA-HYDROXYPREGNENOLONE TO 17-ALPHA-HYDROXYPROGESTERONE BY THE CANINE TESTIS IN VIVO.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androgens; Animals; Carbon Isotopes; Chorionic Gonadotropin; Chromatography; Dogs; Gonadotropins; Humans; Hydroxyprogesterones; Iliac Artery; Male; Metabolism; Pharmacology; Pregnenolone; Research; Testis; Testosterone; Tritium; Ultraviolet Rays | 1964 |
EFFECT OF ANDROGENS ON STEROID C-21 HYDROXYLATION.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Androgens; Chemical Phenomena; Chemistry; Dehydroepiandrosterone; Hydrocortisone; Hydroxylation; Hydroxyprogesterones; Metabolism; Metyrapone; Microsomes; Mixed Function Oxygenases; Naphthalenes; Pharmacology; Pregnenolone; Progesterone; Pyridines; Research; Steroids; Testosterone | 1964 |
C-19-O-2 STEROIDS AND SOME OF THEIR PRECURSORS IN BLOOD FROM NORMAL HUMAN ADRENALS.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Androgens; Blood; Carbon Isotopes; Chromatography; Humans; Hydroxyprogesterones; Infrared Rays; Metabolism; Physiology; Pregnenolone; Testosterone; Tritium | 1965 |
STUDIES ON THE METABOLISM OF C-21 STEROIDS IN THE HUMAN FOETO-PLACENTAL UNIT. I. FORMATION OF A BETA-UNSATURATED 3-KETONES IN MIDTERM PLACENTAS PERFUSED IN SITU WITH PREGNENOLONE AND 17-ALPHA-HYDROXYPREGNENOLONE.
Topics: 17-alpha-Hydroxypregnenolone; Female; Fetus; Humans; Ketones; Maternal-Fetal Exchange; Metabolism; Placenta; Pregnancy; Pregnenolone; Progesterone; Steroids; Tritium; Urine | 1965 |
IMPLANTATION IN THE RABBIT FOLLOWING ADMINISTRATION OF 20-ALPHA-HYDROXYPREGNEN-3-ONE AND 20-BETA-HYDROXYPREGNEN-3-ONE.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Corpus Luteum; Embryo Implantation; Female; Humans; Hydroxyprogesterones; Ovum; Pharmacology; Pregnancy; Pregnenolone; Progesterone; Rabbits; Research | 1965 |
SYNTHESIS OF PREGNENOLONE SULFATE, DEHYDROISOANDROSTERONE SULFATE, 17-ALPHA-HYDROXYPREGNENOLONE SULFATE AND DELTA-5-PREGNENETRIOL SULFATE BY THE NORMAL HUMAN ADRENAL GLAND.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Crystallization; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Metabolism; Pregnanediol; Pregnanetriol; Pregnenes; Pregnenolone; Sulfates; Tritium | 1965 |
SYNTHESIS OF STEROIDS IN THE NEWBORN HUMAN ADRENAL IN VITRO.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Aging; Carbon Isotopes; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydrocortisone; In Vitro Techniques; Infant, Newborn; Metabolism; NADP; Pregnenolone; Progesterone; Radiometry; Steroids | 1965 |
FURTHER OBSERVATIONS ON 3-BETA-HYDROXYSTEROID DEHYDROGENASE ACTIVITY IN THE MOUSE LEYDIG CELL.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Animals; Humans; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Metabolism; Mice; Pharmacology; Pregnenolone; Research; Testis | 1965 |
3-BETA-HYDROXYSTEROID DEHYDROGENASE IN THE ADRENAL GLAND AND PLACENTA.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Animals; Female; Haplorhini; Hydroxysteroid Dehydrogenases; Metabolism; Placenta; Pregnancy; Pregnenolone; Rats | 1965 |
ANDROGEN SYNTHESIS BY TESTICULAR TISSUE FROM A PATIENT WITH GONADAL INSUFFICIENCY.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Androgens; Biopsy; Chromatography; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Hypogonadism; Leydig Cells; Male; Metabolism; Pathology; Pregnenolone; Sertoli Cells; Spermatozoa; Testis; Testosterone; Tritium | 1965 |
3BETA: 21-DIHYDROXYPREGN-5-ENE-20-ONE IN URINE OF NORMAL NEWBORN INFANTS AND IN THIRD DAY URINE OF CHILD WITH DEFICIENCY OF 3BETA-HYDROXYSTEROID-DEHYDROGENASE.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Female; Humans; Hydroxysteroid Dehydrogenases; Hydroxysteroids; Infant, Newborn; Infant, Premature; Metabolism; Metabolism, Inborn Errors; Pregnancy; Pregnancy in Diabetics; Pregnenolone; Urine | 1965 |
STEROID TRANSFORMATIONS IN VITRO BY TESTICULAR TISSUE FROM TWO CASES OF TESTICULAR FEMINISATION.
Topics: 17-alpha-Hydroxypregnenolone; Androgen-Insensitivity Syndrome; Androgens; Chromatography; Cryptorchidism; Dehydroepiandrosterone; Disorders of Sex Development; Humans; In Vitro Techniques; Male; Metabolism; Pregnenolone; Progesterone; Steroids; Testicular Neoplasms; Testis; Testosterone | 1965 |
[INFECTION AND STEROIDS. IN VITRO BIOSYNTHESIS AND CONJUGATION OF STEROIDS IN INFECTION].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Dehydroepiandrosterone; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Pregnenolone; Research; Salmonella Infections; Salmonella Infections, Animal; Steroids | 1965 |
METABOLISM OF PREGNENOLONE-3-SULPHATE IN THE PERFUSED DOG LIVER.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Chromatography; Dehydroepiandrosterone; Dogs; Liver; Perfusion; Pregnenolone; Progesterone; Research; Sulfates; Testosterone | 1965 |
3-BETA-HYDROXYSTEROID DEHYDROGENASE ACTIVITY IN THE MOUSE OVARY.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Androgens; Animals; Corpus Luteum; Female; Histocytochemistry; Humans; Hydroxysteroid Dehydrogenases; Mice; Ovary; Pregnenolone; Research; Tetrazolium Salts | 1965 |
METABOLIC PATTERNS OF STEROID BIOSYNTHESIS IN YOUNG AND AGED HUMAN TESTES.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Aging; Androgens; Chromatography; Estrone; Humans; Hydroxyprogesterones; Lyases; Male; Metabolism; Mixed Function Oxygenases; Pregnenolone; Testis | 1965 |
Conversion of 17alpha-hydroxypregnenolone to cortisol.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Humans; Hydrocortisone; Lipid Metabolism; Pregnenolone | 1961 |
17alpha-Hydroxypregnenolone as a precursor of urinary steroids in a patient with a virilizing adenoma of the adrenal.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Female; Humans; Pregnenolone; Steroids; Virilism | 1961 |
Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia.
Topics: 17-alpha-Hydroxypregnenolone; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dementia, Vascular; Dipeptides; Female; Glutathione; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Pregnenolone; Radioimmunoassay; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric; Sulfhydryl Compounds | 2004 |
7alpha-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Brain; Brain Chemistry; Breeding; Dopamine; Male; Motor Activity; Neurons; Pregnenolone; Salamandridae | 2004 |
Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Child; Chromatography, Liquid; Cortodoxone; Female; Humans; Indicator Dilution Techniques; Male; Middle Aged; Pregnenolone; Reference Values; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2006 |
Adrenal steroid concentrations in children seven to seventeen years of age.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Age Factors; Analysis of Variance; Androstenedione; Child; Chromatography, High Pressure Liquid; Cortodoxone; Dehydroepiandrosterone Sulfate; Female; Humans; Immunoassay; Male; Pregnenolone; Puberty; Sex Factors; Sexual Maturation; Steroids; Tandem Mass Spectrometry; Testosterone | 2007 |
Simultaneous determination of pregnenolone and 17α-hydroxypregnenolone by semi-micro high-performance liquid chromatography with an immobilized cholesterol oxidase as a pre-column reactor: application to bovine adrenal fasciculata cells.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Animals; Cattle; Cells, Cultured; Cholesterol Oxidase; Enzymes, Immobilized; Linear Models; Pregnenolone; Progesterone; Sensitivity and Specificity; Zona Fasciculata | 2010 |
Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17) isoforms.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Chlorocebus aethiops; Chromatography, High Pressure Liquid; COS Cells; Hydrocortisone; Liquid-Liquid Extraction; Male; Mutagenesis, Site-Directed; Pregnenolone; Progesterone; Protein Isoforms; Real-Time Polymerase Chain Reaction; Sheep, Domestic; Steroid 17-alpha-Hydroxylase; Tandem Mass Spectrometry | 2013 |
Synthesis of [3α-(3) H] 17α-hydroxy pregnenolone and [3α-(3) H] pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Chemistry Techniques, Synthetic; Pregnenolone; Radiochemistry; Stereoisomerism; Tritium | 2014 |
Unveiling the crucial intermediates in androgen production.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Biocatalysis; Biosynthetic Pathways; Dehydroepiandrosterone; Humans; Hydrogen Bonding; Hydroxylation; Models, Chemical; Models, Molecular; Molecular Structure; Pregnenolone; Protein Conformation; Spectrophotometry; Steroid 17-alpha-Hydroxylase; Substrate Specificity; Temperature | 2015 |
Age-dependent Increases in Adrenal Cytochrome b5 and Serum 5-Androstenediol-3-sulfate.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adult; Age Factors; Androstenediol; Cell Culture Techniques; Child; Child, Preschool; Cytochromes b5; Dehydroepiandrosterone Sulfate; Female; Human Development; Humans; Infant; Male; Pregnenolone; Progesterone Reductase; Young Adult | 2016 |
Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Biomarkers; Ethanol; Female; Gene Regulatory Networks; Genetic Variation; Inhalation Exposure; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neurotransmitter Agents; Pregnenolone; Species Specificity; Steroids | 2017 |
11-Oxygenated Androgens Are Biomarkers of Adrenal Volume and Testicular Adrenal Rest Tumors in 21-Hydroxylase Deficiency.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adult; Age Determination by Skeleton; Aged; Androgens; Androstenedione; Androstenes; Child; Child, Preschool; Cortodoxone; Cross-Sectional Studies; Female; Hirsutism; Humans; Hydroxytestosterones; Male; Menstruation Disturbances; Middle Aged; Organ Size; Pregnenolone; Testicular Neoplasms; Testosterone; Young Adult | 2017 |
Cortisol precursors in neonates with vasopressor-resistant hypotension in relationship to demographic characteristics.
Topics: 17-alpha-Hydroxypregnenolone; Cohort Studies; Dehydroepiandrosterone; Drug Resistance; Female; Gestational Age; Humans; Hydrocortisone; Hypotension; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pregnenolone; Risk Factors; Treatment Failure; Vasoconstrictor Agents | 2018 |
Characterizing the steroidal milieu in amniotic fluid of mid-gestation: A LC-MS/MS study.
Topics: 17-alpha-Hydroxypregnenolone; Amniotic Fluid; Androsterone; Chromatography, Liquid; Dehydroepiandrosterone; Epitestosterone; Estriol; Estrone; Female; Gestational Age; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Steroids; Tandem Mass Spectrometry | 2019 |
Impact of Gestational and Postmenstrual Age on Excretion of Fetal Zone Steroids in Preterm Infants Determined by Gas Chromatography-Mass Spectrometry.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Aging; Amniotic Fluid; Cohort Studies; Dehydroepiandrosterone Sulfate; Female; Fetus; Gas Chromatography-Mass Spectrometry; Gestational Age; Humans; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Male; Pregnancy; Pregnenolone; Sex Characteristics; Steroids | 2021 |
Corticosteroid Biosynthesis Revisited: No Direct Hydroxylation of Pregnenolone by Steroid 21-Hydroxylase.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Catalytic Domain; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Models, Molecular; Molecular Docking Simulation; Pregnenolone; Progesterone; Schizosaccharomyces; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Steroids; Substrate Specificity | 2021 |
COVID-19 patients with altered steroid hormone levels are more likely to have higher disease severity.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldosterone; Androstenedione; Androsterone; Chromatography, Liquid; Corticosterone; Cortodoxone; COVID-19; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Estradiol; Estrone; Humans; Hydrocortisone; Pregnenolone; Progesterone; Severity of Illness Index; Tandem Mass Spectrometry | 2022 |
Follicle isolation methods reveal plasticity of granulosa cell steroidogenic capacity during mouse in vitro follicle growth.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Alginates; Alkaline Phosphatase; Androgens; Androstenedione; Animals; Carrier Proteins; Dehydroepiandrosterone; Estradiol; Female; Granulosa Cells; Humans; Inhibins; Lyases; Mice; Pregnenolone; Progesterone; Theca Cells | 2022 |