pregnanolone has been researched along with tert-butylbicyclophosphorothionate in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (64.71) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cadoni, C; Gee, KW | 1 |
| Gee, KW; Lan, NC | 1 |
| Blakeman, DP; Im, WB | 1 |
| Belelli, D; Gee, KW; McCauley, L | 1 |
| Ticku, MK; Yu, R | 1 |
| Moore, FL; Murray, TF; Orchinik, M | 1 |
| Dartois, E; Fillion, G; Haour, F; Marquette, C; Moyse, E; Popelier, M; Vincens, M | 1 |
| Belfiore, MS; Giusti, L; Lucacchini, A; Martini, C | 1 |
| Finn, DA; Gee, KW | 1 |
| Canonaco, M; Maggi, A; Tavolaro, R | 1 |
| Gee, KW; McCauley, LD | 1 |
| Devaud, LL; Morrow, AL; Paul, SM; Purdy, RH | 1 |
| Chen, JS; Drewe, JA; Gee, KW; Hawkinson, JE; Hogenkamp, DJ; Kimbrough, CL; Lan, NC; Shen, KZ; Whittemore, ER; Woodward, RM | 1 |
| Barbaccia, ML; Biggio, G; Concas, A; Lener, R; Mostallino, MC; Perra, C; Purdy, RH; Roscetti, G | 1 |
| Feltz, P; Larmet, Y; Ohannesian, L; Poulter, MO | 1 |
| Acosta-Burruel, M; Carter, RB; Hawkinson, JE; Konkoy, CS; Lan, NC; McLellan, JA; Upasani, RB; Woodward, RM; Yang, KC | 1 |
| Belelli, D; Bolger, MB; Carter, RB; Gee, KW; Hawkinson, JE; Lambert, JJ; Lan, NC; Mirsadeghi, S; Tahir, SH; White, HS; Wieland, S; Wolf, HH; Wood, PL | 1 |
| Davies, PA; Hales, TG; Kirkness, EF | 1 |
| Firestone, LL; Homanics, GE; Korpi, ER; Mäkelä, R; Quinlan, JJ; Uusi-Oukari, M; Wisden, W | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Acosta-Burruel, M; Carter, RB; Chen, JS; Drewe, JA; Hawkinson, JE; Hogenkamp, DJ; Lan, NC; Upasani, RB; Whittemore, ER; Woodward, RM; Yang, KC | 1 |
| Barbaccia, ML; Biggio, G; Concas, A; Follesa, P; Purdy, RH | 1 |
| Beart, PM; Crossley, KJ; Hirst, JJ; Walker, DW | 1 |
| Covey, DF; Evers, AS; Hu, Y; Kalkbrenner, M; Nathan, D; Nilsson, KR; Zorumski, CF | 1 |
| Barrett, JE; Belluzzi, JD; Carter, RB; Hawkinson, JE; Lan, NC; Rosenzweig-Lipson, S; Stein, L; Vanover, KE; Wood, PL | 1 |
| Barbaccia, ML; Foddi, C; Ghezzi, P; Mennini, T; Sacco, S; Santo, ED | 1 |
| Gillardin, JM; Neliat, G; Pansart, Y; Schlichter, R; Verleye, M | 1 |
| Chigr, F; M'hamed, SB; Najimi, M | 1 |
| Akk, G; Bracamontes, JR; Covey, DF; Darbandi-Tonkabon, R; Evers, AS; Hastings, WR; Manion, BD; Mennerick, SJ; Steinbach, JH; Zeng, CM | 1 |
| Brussaard, AB; Koksma, JJ; Lüddens, H; Rosahl, TW; Smit, AB; van Kesteren, RE; Zwart, R | 1 |
| Akk, G; Bracamontes, JR; Covey, DF; Craigen, WJ; Darbandi-Tonkabon, R; Evers, AS; Hastings, WR; He, Y; Manion, BD; Mennerick, SJ; Sheiko, TV; Steinbach, JH | 1 |
| Gillardin, JM; Heulard, I; Verleye, M | 1 |
| Akk, G; Covey, DF; Elias, G; Evers, AS; Krishnan, K; Kudova, E; Li, P; Manion, BD; Mennerick, S; Qian, M; Taylor, A; Zorumski, CF | 1 |
| Burton, G; Coirini, H; Ghini, AA; Kruse, MS; Rey, M; Veleiro, AS | 1 |
1 review(s) available for pregnanolone and tert-butylbicyclophosphorothionate
| Article | Year |
|---|---|
Neuroactive steroid modulators of the stress response.
Topics: Adrenalectomy; Alcoholism; Animals; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Estrus; Female; Flunitrazepam; Hypothalamo-Hypophyseal System; Male; Menstruation; Pregnancy; Pregnanolone; Pregnenolone; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Stress, Physiological | 1995 |
33 other study(ies) available for pregnanolone and tert-butylbicyclophosphorothionate
| Article | Year |
|---|---|
Complex interactions between the steroid derivative RU 5135 and the GABAA-receptor complex.
Topics: Androstanes; Animals; Azasteroids; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pregnanediol; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereoisomerism | 1992 |
Gamma-aminobutyric acidA receptor complexes in rat frontal cortex and spinal cord show differential responses to steroid modulation.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Desoxycorticosterone; Diazepam; gamma-Aminobutyric Acid; Ionophores; Male; Pentobarbital; Pregnanediol; Pregnanolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Steroids; Sulfur Radioisotopes | 1991 |
Correlation between gamma-aminobutyric acidA receptor ligand-induced changes in t-butylbicyclophosphoro[35S]thionate binding and 36Cl- uptake in rat cerebrocortical membranes.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; Diazepam; Ethanol; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Membrane Proteins; Pentobarbital; Pregnanolone; Rats; Receptors, GABA-A; Synaptosomes | 1991 |
Heterotropic cooperativity between putative recognition sites for progesterone metabolites and the atypical benzodiazepine Ro 5-4864.
Topics: Animals; Benzodiazepinones; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Convulsants; gamma-Aminobutyric Acid; Male; Pregnanediol; Pregnanolone; Progesterone; Rats; Rats, Inbred Strains | 1990 |
Chronic neurosteroid treatment produces functional heterologous uncoupling at the gamma-aminobutyric acid type A/benzodiazepine receptor complex in mammalian cortical neurons.
Topics: Androstanes; Animals; Azasteroids; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebral Cortex; Chlorides; Chlorine; Convulsants; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Neurons; Pregnanolone; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Sulfur Radioisotopes; Time Factors; Tritium | 1995 |
Steroid modulation of GABAA receptors in an amphibian brain.
Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Convulsants; Corticosterone; Flunitrazepam; Kinetics; Male; Mammals; Neurons; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Salamandridae; Species Specificity; Steroids; Sulfur Radioisotopes; Synaptosomes; Tritium | 1994 |
Autoradiographic study of neurosteroid binding sites labelled with [35S]-TBPS in brain of different species.
Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Female; Guinea Pigs; Male; Mesencephalon; Mice; Mice, Inbred C3H; Organ Specificity; Picrotoxin; Pregnanolone; Rats; Rats, Wistar; Receptors, Steroid; Species Specificity; Sulfur Radioisotopes | 1993 |
3 alpha-hydroxy-5 alpha-pregnan-20-one modulation of solubilized GABA/benzodiazepine receptor complex.
Topics: Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; Pregnanolone; Radioligand Assay; Rats; Receptors, GABA-A; Solubility | 1993 |
The influence of estrus cycle on neurosteroid potency at the gamma-aminobutyric acidA receptor complex.
Topics: Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Estrus; Female; gamma-Aminobutyric Acid; Male; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sex Factors | 1993 |
Steroid hormones and receptors of the GABAA supramolecular complex. II. Progesterone and estrogen inhibitory effects on the chloride ion channel receptor in different forebrain areas of the female rat.
Topics: Animals; Autoradiography; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Estradiol; Female; In Vitro Techniques; Pregnanolone; Progesterone; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, GABA; Tissue Distribution | 1993 |
Influence of the estrus cycle on the discrimination of apparent neuroactive steroid site subtypes on the gamma-aminobutyric acidA receptor complex in the rat.
Topics: Allosteric Regulation; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Estrus; Female; Male; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sex Characteristics; Sulfur Radioisotopes | 1995 |
3 alpha-Hydroxy-3 beta-trifluoromethyl-5 alpha-pregnan-20-one (Co 2-1970): a partial agonist at the neuroactive steroid site of the gamma-aminobutyric acidA receptor.
Topics: Allosteric Regulation; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Convulsants; GABA Agonists; Humans; Ion Channel Gating; Pregnanolone; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Xenopus laevis | 1996 |
Functional correlation between allopregnanolone and [35S]-TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress.
Topics: Animals; Antitubercular Agents; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; GABA Modulators; Injections, Intraventricular; Isoniazid; Male; Pentylenetetrazole; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Stress, Physiological; Time Factors | 1996 |
Evidence that GABAA receptor subunit mRNA expression during development is regulated by GABAA receptor stimulation.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cells, Cultured; Cerebral Cortex; Convulsants; GABA Modulators; GABA-A Receptor Agonists; Gene Expression Regulation, Developmental; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger | 1997 |
3 alpha-Hydroxy-3 beta-(phenylethynyl)-5 beta-pregnan-20-ones: synthesis and pharmacological activity of neuroactive steroids with high affinity for GABAA receptors.
Topics: Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Electrophysiology; Electroshock; Female; GABA Modulators; Humans; Isomerism; Mice; Oocytes; Pregnanolone; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus | 1997 |
Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor.
Topics: Animals; Anticonvulsants; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; GABA Modulators; Humans; In Vitro Techniques; Kindling, Neurologic; Mice; Pregnanolone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Seizures | 1997 |
Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells.
Topics: Anesthetics, General; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; gamma-Aminobutyric Acid; Humans; Pentobarbital; Pregnanolone; Propofol; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sulfur Radioisotopes | 1997 |
Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebellum; Convulsants; Diazepam; Diuretics; Furosemide; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Mutation; Pregnanolone; Pyridazines; Receptors, GABA-A; Sulfur Radioisotopes; Tritium; Zinc | 1997 |
Chronic ethanol administration alters the modulatory effect of 5alpha-pregnan-3alpha-ol-20-one on the binding characteristics of various radioligands of GABAA receptors.
Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Ethanol; Flunitrazepam; GABA Agonists; GABA Modulators; Hippocampus; Male; Muscimol; Pregnanolone; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; GABA Modulators; Humans; Male; Mice; Muscimol; Pregnanolone; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus | 1998 |
Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.
Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Drug Interactions; Enzyme Inhibitors; Estrus; Female; Finasteride; Flunitrazepam; GABA Modulators; Gestational Age; Hippocampus; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Characterisation of GABA(A) receptors in fetal, neonatal and adult ovine brain: region and age related changes and the effects of allopregnanolone.
Topics: Aging; Animals; Animals, Newborn; Binding, Competitive; Brain; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Female; Fetus; Frontal Lobe; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Picrotoxin; Pregnancy; Pregnanolone; Receptors, GABA-A; Sheep; Sulfur Radioisotopes | 2000 |
Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia.
Topics: Anesthetics; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; GABA Modulators; Larva; Mice; Mice, Inbred BALB C; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Species Specificity; Stereoisomerism; Structure-Activity Relationship | 2000 |
Characterization of the anxiolytic properties of a novel neuroactive steroid, Co 2-6749 (GMA-839; WAY-141839; 3alpha, 21-dihydroxy-3beta-trifluoromethyl-19-nor-5beta-pregnan-20-one), a selective modulator of gamma-aminobutyric acid(A) receptors.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Columbidae; Conflict, Psychological; GABA Modulators; Humans; Male; Motor Activity; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Saimiri | 2000 |
Neurosteroid levels are increased in vivo after LPS treatment and negatively regulate LPS-induced TNF production.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Dehydroepiandrosterone Sulfate; Hippocampus; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Pregnanolone; Pregnenolone; Progesterone; Tumor Necrosis Factor-alpha | 2000 |
Functional modulation of gamma-aminobutyric acid(A) receptors by etifoxine and allopregnanolone in rodents.
Topics: Allosteric Site; Animals; Anticonvulsants; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Convulsants; Drug Interactions; GABA Antagonists; Male; Oxazines; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes | 2001 |
Modulation Of [35S]-tert-butylbicyclophosphorothionate binding by somatostatin in rat hypothalamus.
Topics: Animals; Bicuculline; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Somatostatin; Sulfur Radioisotopes | 2002 |
Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain.
Topics: Affinity Labels; Animals; Aziridines; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Female; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Muscimol; Oocytes; Porins; Pregnanolone; Rats; Recombinant Proteins; Steroids; Telencephalon; Transfection; Voltage-Dependent Anion Channel 1; Voltage-Dependent Anion Channels; Xenopus laevis | 2003 |
Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition.
Topics: Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Female; gamma-Aminobutyric Acid; Humans; Kidney; Ligands; Male; Mice; Mice, Knockout; Mice, Transgenic; Oocytes; Oxytocin; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Pregnancy; Pregnanolone; Protein Kinase C; Rats; Rats, Wistar; Receptors, GABA-A; Steroids; Supraoptic Nucleus; Transfection; Xenopus | 2003 |
Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia.
Topics: Anesthesia; Animals; Aziridines; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Electrophysiology; Fibroblasts; Immunoblotting; Ion Channels; Mice; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Photochemistry; Porins; Pregnanolone; Receptors, GABA-A; Steroids; Sulfur Radioisotopes; Voltage-Dependent Anion Channel 1; Voltage-Dependent Anion Channel 2; Voltage-Dependent Anion Channels | 2004 |
Investigation of the anticonvulsive effect of acute immobilization stress in anxious Balb/cByJ mice using GABA A-related mechanistic probes.
Topics: Allosteric Regulation; Animals; Anxiety; Bridged Bicyclo Compounds, Heterocyclic; Clonazepam; Convulsants; Drug Interactions; Finasteride; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Oxazines; Picrotoxin; Pregnanolone; Progesterone; Receptors, GABA-A; Restraint, Physical; Seizures; Stress, Psychological | 2008 |
Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; GABA Modulators; HEK293 Cells; Humans; Models, Molecular; Neurotransmitter Agents; Pregnanediones; Pregnanolone; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis | 2014 |
Effect of synthetic steroids on GABAA receptor binding in rat brain.
Topics: Animals; Autoradiography; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; GABA-A Receptor Agonists; Hippocampus; Male; Muscimol; Pregnanolone; Protein Binding; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Tritium | 2015 |