pregnanolone has been researched along with morphine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Colburn, RW; Coombs, DW; DeLeo, JA; Winfree, CJ | 1 |
| Meloche, R; Prys-Roberts, C | 1 |
| Chapman, JM; Cooper, GM; Gray, AJ; Prys-Roberts, C; Sear, JW; Simpson, PJ | 1 |
| Kulkarni, SK; Reddy, DS | 1 |
| Czuchwicki, A; Ilsley, AH; Love, DR; Owen, H; Plummer, JL | 1 |
| Bowen, CA; Gatto, GJ; Grant, KA | 1 |
| Bachtell, RK; Ryabinin, AE; Tsivkovskaia, NO | 1 |
| Gingras, M; Le Moal, M; Marinelli, M; Mayo, W; Piazza, PV; Rougé-Pont, F | 1 |
| Grobin, AC; Morrow, AL; Porrino, LJ; VanDoren, MJ | 1 |
| Biggio, G; Brundu, A; Concas, A; Marra, C; Porcu, P; Sogliano, C | 1 |
| Gerak, LR | 1 |
| Elfverson, M; Johansson, T; Nyberg, F; Zhou, Q | 1 |
| Eppolito, AK; Gerak, LR; Kodeih, HR | 1 |
2 review(s) available for pregnanolone and morphine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Management of anesthesia in patients with hypertension or ischemic heart disease.
Topics: Alfaxalone Alfadolone Mixture; Analgesics; Anesthesia; Anesthesia, Conduction; Anesthesia, Local; Coronary Disease; Emergencies; Fentanyl; Fluid Therapy; Humans; Hypertension; Monitoring, Physiologic; Morphine; Narcotics; Postoperative Care; Pregnanolone; Premedication; Surgical Procedures, Operative | 1980 |
1 trial(s) available for pregnanolone and morphine
| Article | Year |
|---|---|
Influence of premedication with diazepam or morphine on the induction dose of eltanolone.
Topics: Adjuvants, Anesthesia; Administration, Oral; Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Confidence Intervals; Diazepam; Double-Blind Method; Female; Humans; Incidence; Injections, Intramuscular; Logistic Models; Male; Middle Aged; Morphine; Movement; Placebos; Preanesthetic Medication; Pregnanolone | 1998 |
12 other study(ies) available for pregnanolone and morphine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Analgesic effects of intrathecally-administered 3 alpha-hydroxy-5 alpha-pregnan-20-one in a rat mechanical visceral pain model.
Topics: Analgesics; Animals; Disease Models, Animal; Injections, Spinal; Male; Morphine; Pain; Pregnanolone; Rats; Spinal Cord | 1992 |
Studies on premedication and ventilatory responses to minaxolone.
Topics: Adult; Anesthetics; Atropine; Diazepam; Female; Humans; Male; Morphine; Nitrous Oxide; Oxygen; Preanesthetic Medication; Pregnanes; Pregnanolone; Respiration; Time Factors | 1981 |
Chronic neurosteroid treatment prevents the development of morphine tolerance and attenuates abstinence behavior in mice.
Topics: Analgesics, Opioid; Animals; Dehydroepiandrosterone; Drug Tolerance; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pregnanolone; Pregnenolone; Reaction Time; Steroids; Substance Withdrawal Syndrome | 1997 |
Assessment of the multiple discriminative stimulus effects of ethanol using an ethanol-pentobarbital-water discrimination in rats.
Topics: Animals; Central Nervous System Depressants; Diazepam; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; GABA Modulators; Hypnotics and Sedatives; Indoles; Male; Midazolam; Morphine; N-Methylaspartate; Narcotics; Pentobarbital; Phencyclidine; Pregnanolone; Quinoxalines; Rats; Rats, Long-Evans; Serotonin Receptor Agonists; Water | 1997 |
Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms.
Topics: Aminoacetonitrile; Animals; Brain; Chlordiazepoxide; Dopamine; Ethanol; Gene Expression Regulation; Genes, fos; Haloperidol; Male; Mice; Mice, Inbred C57BL; Morphine; Norepinephrine; Pregnanolone; Protease Inhibitors; Signal Transduction; Tyrosine 3-Monooxygenase; Yohimbine | 2002 |
The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens.
Topics: Analgesics, Opioid; Animals; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Injections, Intraventricular; Male; Microdialysis; Morphine; Narcotics; Nucleus Accumbens; Pregnanolone; Rats; Rats, Sprague-Dawley | 2002 |
Cortical 3 alpha-hydroxy-5 alpha-pregnan-20-one levels after acute administration of Delta 9-tetrahydrocannabinol, cocaine and morphine.
Topics: Animals; Cerebral Cortex; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Male; Morphine; Pregnanolone; Rats; Rats, Sprague-Dawley | 2005 |
Neurosteroids in nicotine and morphine dependence.
Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2006 |
Selective changes in sensitivity to benzodiazepines, and not other positive GABA(A) modulators, in rats receiving flunitrazepam chronically.
Topics: Animals; Benzodiazepines; Binding Sites; Dose-Response Relationship, Drug; Drug Tolerance; Flunitrazepam; Ketamine; Male; Midazolam; Morphine; Pentobarbital; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reinforcement Schedule; Substance-Related Disorders | 2009 |
Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration.
Topics: Allosteric Regulation; Animals; Brain; Dehydroepiandrosterone; Male; Morphine; Neurotransmitter Agents; Opioid-Related Disorders; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2010 |
Using drug combinations to assess potential contributions of non-GABAA receptors in the discriminative stimulus effects of the neuroactive steroid pregnanolone in rats.
Topics: Animals; Biguanides; Central Nervous System Depressants; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Modulators; Male; Midazolam; Morphine; Narcotics; Phencyclidine; Pregnanolone; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists | 2014 |