Page last updated: 2024-08-23

pregnanolone and mifepristone

pregnanolone has been researched along with mifepristone in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's5 (33.33)18.2507
2000's6 (40.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brann, DW; Kolbeck, RC; Mahesh, VB; Putnam, CD1
Brann, DW; Mahesh, VB; Putnam, CD1
Bauer, H; Bauer, HC1
Beyer, C; González-Flores, O; González-Mariscal, G1
Bitran, D; McLeod, M; Shiekh, M1
Kubli-Garfias, C; Perusquía, M1
Murphy, DD; Segal, M1
Carlen, PL; Edwards, HE; Epps, T; J MacLusky, N1
Sakamoto, H; Tsutsui, K; Ukena, K1
Kamernitskii, AV; Kareva, EN; Kirpichnikova, NV; Kulikova, LE; Levina, IS; Podval'nyuk, VV1
Frye, CA; Sumida, K; Walf, AA1
Debonnel, G; Robichaud, M1
Adams, S; Hassell, J; Hiegel, C; Miryala, CS; Uphouse, L1
Ishida, A; Ishihara, Y; Kawami, T; Yamazaki, T1
Harada, K; Inoue, M; Matsuoka, H; Nakamura, J1

Other Studies

15 other study(ies) available for pregnanolone and mifepristone

ArticleYear
Inhibition of uterine contractility by progesterone and progesterone metabolites: mediation by progesterone and gamma amino butyric acidA receptor systems.
    Biology of reproduction, 1991, Volume: 45, Issue:2

    Topics: 5-alpha-Dihydroprogesterone; Animals; Depression, Chemical; Diestrus; Drug Interactions; Female; GABA-A Receptor Antagonists; Mifepristone; Picrotoxin; Pregnanediones; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; Receptors, Progesterone; Uterine Contraction

1991
Gamma-aminobutyric acidA receptors mediate 3 alpha-hydroxy-5 alpha-pregnan-20-one-induced gonadotropin secretion.
    Endocrinology, 1990, Volume: 126, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Gonadotropins; Luteinizing Hormone; Mifepristone; Picrotoxin; Pregnanes; Pregnanolone; Rats; Rats, Inbred Strains; Receptors, GABA-A

1990
Effects of progesterone, epipregnanolone and RU 38486 on potassium uptake in cultured cortical neurons.
    Journal of steroid biochemistry, 1990, Jul-04, Volume: 36, Issue:4

    Topics: Animals; Biological Transport; Cells, Cultured; Cerebral Cortex; Furosemide; Kinetics; Mice; Mice, Inbred BALB C; Mifepristone; Neurons; Ouabain; Potassium; Pregnanes; Pregnanolone; Progesterone; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase

1990
Intrahypothalamic injection of RU486 antagonizes the lordosis induced by ring A-reduced progestins.
    Physiology & behavior, 1989, Volume: 46, Issue:3

    Topics: 5-alpha-Dihydroprogesterone; Animals; Drug Interactions; Estradiol; Female; Mifepristone; Ovariectomy; Posture; Pregnanediones; Pregnanes; Pregnanolone; Progesterone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Time Factors; Ventromedial Hypothalamic Nucleus

1989
Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAA receptors.
    Journal of neuroendocrinology, 1995, Volume: 7, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Azasteroids; Brain; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Estrus; Female; Mifepristone; Ovariectomy; Ovary; Oxidoreductases; Picrotoxin; Pregnanolone; Progesterone; Rats; Receptors, GABA-A

1995
Progesterone-like relaxant effect of RU 486 in the rat myometrium.
    Life sciences, 1994, Volume: 54, Issue:20

    Topics: Animals; Calcium; Female; In Vitro Techniques; Mifepristone; Muscle Relaxation; Muscle, Smooth; Myometrium; Potassium; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Time Factors; Uterine Contraction

1994
Progesterone prevents estradiol-induced dendritic spine formation in cultured hippocampal neurons.
    Neuroendocrinology, 2000, Volume: 72, Issue:3

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Size; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dendrites; Drug Interactions; Estradiol; Fetus; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Indomethacin; Microscopy, Electron; Mifepristone; Neuronal Plasticity; Patch-Clamp Techniques; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Signal Transduction

2000
Progestin receptors mediate progesterone suppression of epileptiform activity in tetanized hippocampal slices in vitro.
    Neuroscience, 2000, Volume: 101, Issue:4

    Topics: Animals; Drug Combinations; Electric Stimulation; Epilepsy; Female; Hippocampus; Hormone Antagonists; In Vitro Techniques; Mifepristone; Pregnanolone; Progesterone; Progesterone Congeners; Promegestone; Rats; Rats, Wistar; Reaction Time; Receptors, Progesterone

2000
Effects of progesterone synthesized de novo in the developing Purkinje cell on its dendritic growth and synaptogenesis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Aug-15, Volume: 21, Issue:16

    Topics: Animals; Animals, Newborn; Calbindins; Cerebellum; Dendrites; Dose-Response Relationship, Drug; Female; Hormone Antagonists; In Vitro Techniques; Male; Mifepristone; Pregnanolone; Progesterone; Purkinje Cells; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Receptors, Progesterone; RNA, Messenger; S100 Calcium Binding Protein G; Synapses

2001
Antiprogestagen activity of 5H-progesterone metabolites and their analogues, 16alpha,17alpha-cyclohexane-5H-pregnan-3,20-diones.
    Bulletin of experimental biology and medicine, 2001, Volume: 131, Issue:4

    Topics: Abortifacient Agents, Steroidal; Animals; Female; Mifepristone; Molecular Structure; Pregnancy; Pregnancy Maintenance; Pregnancy, Animal; Pregnanolone; Progesterone; Progestins; Rats

2001
Progestins' actions in the VTA to facilitate lordosis involve dopamine-like type 1 and 2 receptors.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Female; gamma-Aminobutyric Acid; Mifepristone; Posture; Pregnanolone; Quinpirole; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D2; Sexual Behavior, Animal; Sulpiride; Ventral Tegmental Area

2004
Allopregnanolone and ganaxolone increase the firing activity of dorsal raphe nucleus serotonergic neurons in female rats.
    The international journal of neuropsychopharmacology, 2006, Volume: 9, Issue:2

    Topics: Action Potentials; Analysis of Variance; Anesthetics; Animals; Citalopram; Drug Interactions; Female; Hormone Antagonists; Mifepristone; Neurons; Pregnanolone; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors

2006
RU486 blocks effects of allopregnanolone on the response to restraint stress.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 103, Issue:3

    Topics: Animals; Drug Interactions; Female; Male; Mifepristone; Posture; Pregnanolone; Rats; Rats, Inbred F344; Receptors, Progesterone; Sexual Behavior, Animal; Stress, Psychological

2013
Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices.
    The Journal of steroid biochemistry and molecular biology, 2013, Volume: 135

    Topics: 5-alpha Reductase Inhibitors; Anesthetics; Animals; Bicuculline; Cell Death; Cytochrome P-450 Enzyme Inhibitors; Finasteride; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hippocampus; Hormone Antagonists; Mifepristone; Muscimol; Neurons; Neuroprotective Agents; Organ Culture Techniques; Pregnanolone; Progesterone; Progestins; Rats; Rats, Wistar; Tetrahydronaphthalenes; Trialkyltin Compounds

2013
Regulation of α3-containing GABAA receptors in guinea-pig adrenal medullary cells by adrenal steroids.
    Neuroscience, 2013, Dec-03, Volume: 253

    Topics: Abortifacient Agents, Steroidal; Action Potentials; Adrenal Medulla; Anesthetics; Animals; Carrier Proteins; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Guinea Pigs; Male; Membrane Proteins; Mifepristone; Patch-Clamp Techniques; PC12 Cells; Pregnanolone; Rats; Receptors, GABA-A; Steroids; Zinc

2013