Page last updated: 2024-08-23

pregnanolone and ketamine

pregnanolone has been researched along with ketamine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's1 (6.67)18.2507
2000's5 (33.33)29.6817
2010's2 (13.33)24.3611
2020's5 (33.33)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Clarke, RS1
Evans, DF; Foster, GE; Healy, TE; Syed, A1
Albrecht, S; Hering, W; Schüttler, J; Schwilden, H1
France, CP; McMahon, LR1
Gerak, LR; Moerschbaecher, JM; Stevenson, MW; Winsauer, PJ1
Reddy, DS; Zeng, YC1
Gerak, LR1
Cristea, IA; Naudet, F1
Daly, EJ; Drevets, WC; Fedgchin, M; Hough, D; Mathews, M; Popova, V; Singh, JB1
Deng, ZD; Henter, ID; Kadriu, B; Kraus, C; Lisanby, SH; Zarate, CA1
Lambert, PM; Lu, X; Mennerick, S; Zorumski, CF1
Castro-Zavala, A; Ferreres-Álvarez, I; Gallego-Landin, I; García-Baos, A; Martín-Sánchez, A; Puig-Reyne, X; Valverde, O1
Benz, A; Lambert, PM; Mennerick, S; Ni, R; Rensing, NR; Wong, M; Zorumski, CF1

Reviews

2 review(s) available for pregnanolone and ketamine

ArticleYear
[New intravenous anesthetics. Remifentanil, S(+)-ketamine, eltanolone and target controlled infusion].
    Der Anaesthesist, 1996, Volume: 45, Issue:12

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Humans; Infusions, Intravenous; Ketamine; Piperidines; Pregnanolone; Remifentanil

1996
Physiological markers of rapid antidepressant effects of allopregnanolone.
    Journal of neuroendocrinology, 2022, Volume: 34, Issue:2

    Topics: Antidepressive Agents; Ketamine; Neurosteroids; Pregnanolone

2022

Other Studies

13 other study(ies) available for pregnanolone and ketamine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Comparative merits of intravenous anesthetic agents for outpatient surgery.
    International anesthesiology clinics, 1982,Spring, Volume: 20, Issue:1

    Topics: Alfaxalone Alfadolone Mixture; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics; Drug Hypersensitivity; Etomidate; Humans; Ketamine; Methohexital; Phenols; Pregnanolone; Propanidid; Propofol; Thiopental

1982
Effect of some i.v. anaesthetic agents on canine gastrointestinal motility.
    British journal of anaesthesia, 1981, Volume: 53, Issue:3

    Topics: Action Potentials; Anesthesia, Intravenous; Anesthetics; Animals; Atropine; Dogs; Gastrointestinal Motility; Intestine, Small; Ketamine; Pentolinium Tartrate; Pregnanes; Pregnanolone; Thiopental

1981
Acute and chronic effects of the neuroactive steroid pregnanolone on schedule-controlled responding in rhesus monkeys.
    Behavioural pharmacology, 2002, Volume: 13, Issue:7

    Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Female; Food; GABA Antagonists; GABA Modulators; Ketamine; Macaca mulatta; Male; Pentylenetetrazole; Pregnanolone; Receptors, GABA-A; Reinforcement Schedule; Time Factors; Triazolam

2002
Effects of pregnanolone alone and in combination with other positive GABAA modulators on complex behavior in rats.
    Psychopharmacology, 2004, Volume: 173, Issue:1-2

    Topics: Anesthetics; Animals; Behavior, Animal; Discrimination Learning; Dose-Response Relationship, Drug; Drug Combinations; Excitatory Amino Acid Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Ketamine; Male; Pregnanolone; Rats; Rats, Long-Evans; Reaction Time; Reinforcement Schedule

2004
Differential anesthetic activity of ketamine and the GABAergic neurosteroid allopregnanolone in mice lacking progesterone receptor A and B subtypes.
    Methods and findings in experimental and clinical pharmacology, 2007, Volume: 29, Issue:10

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Female; GABA Agonists; Genotype; Immunochemistry; Injections, Intraperitoneal; Injections, Subcutaneous; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pregnanolone; Protein Isoforms; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Progesterone; Sex Factors; Stereoisomerism

2007
Selective changes in sensitivity to benzodiazepines, and not other positive GABA(A) modulators, in rats receiving flunitrazepam chronically.
    Psychopharmacology, 2009, Volume: 204, Issue:4

    Topics: Animals; Benzodiazepines; Binding Sites; Dose-Response Relationship, Drug; Drug Tolerance; Flunitrazepam; Ketamine; Male; Midazolam; Morphine; Pentobarbital; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reinforcement Schedule; Substance-Related Disorders

2009
US Food and Drug Administration approval of esketamine and brexanolone.
    The lancet. Psychiatry, 2019, Volume: 6, Issue:12

    Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Treatment-Resistant; Drug Combinations; Female; Humans; Ketamine; Pregnanolone; United States; United States Food and Drug Administration

2019
In with the new?
    The lancet. Psychiatry, 2019, Volume: 6, Issue:12

    Topics: beta-Cyclodextrins; Drug Combinations; Ketamine; Pregnanolone; United States; United States Food and Drug Administration

2019
Approval of esketamine for treatment-resistant depression.
    The lancet. Psychiatry, 2020, Volume: 7, Issue:3

    Topics: beta-Cyclodextrins; Depression; Depressive Disorder, Treatment-Resistant; Drug Combinations; Humans; Ketamine; Pregnanolone; United States; United States Food and Drug Administration

2020
Not So Fast: Recent Successes and Failures in Treating Depression.
    The Journal of clinical psychiatry, 2020, 05-26, Volume: 81, Issue:4

    Topics: beta-Cyclodextrins; Depression; Drug Combinations; Excitatory Amino Acid Antagonists; GABA Modulators; Humans; Ketamine; Pregnanolone

2020
Effects of fast-acting antidepressant drugs on a postpartum depression mice model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 154

    Topics: Anhedonia; Animals; Antidepressive Agents; Depression, Postpartum; Disease Models, Animal; Female; Humans; Ketamine; Maternal Deprivation; Mice; Pregnanolone

2022
Non-sedative cortical EEG signatures of allopregnanolone and functional comparators.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023, Volume: 48, Issue:2

    Topics: Animals; Antidepressive Agents; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Humans; Ketamine; Mice; Neurosteroids; Pentobarbital; Pregnanolone; Receptors, GABA-A

2023