pregnanolone has been researched along with indomethacin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Campbell, JS; Karavolas, HJ | 1 |
| Gallo, MA; Smith, SS | 1 |
| ffrench-Mullen, JM; Gong, QH; Hsu, FC; Li, X; Markowitz, RS; Smith, SS | 1 |
| Devaud, LL; Morrow, AL; VanDoren, MJ | 1 |
| Beyer, C; González-Flores, O; González-Mariscal, G; Ramírez-Orduña, JM | 1 |
| Devaud, LL; Grobin, AC; Janis, GC; Matthews, DB; Morrow, AL; VanDoren, MJ | 1 |
| Murphy, DD; Segal, M | 1 |
| Chopde, CT; Deshpande, LS; Khisti, RT | 1 |
| Frye, CA; Vongher, JM | 1 |
| Bernardi, G; di Michele, F; Pace, M; Pasinib, A; Pompili, E; Romeo, E; Rupprecht, R | 1 |
| Ahboucha, S; Baker, GB; Butterworth, RF; Chatauret, N; Jiang, W; Mamer, O | 1 |
| Frye, CA; Paris, JJ; Rhodes, ME | 1 |
| Arora, SK; Chakrabarti, A; Hota, D; Khanduja, KL; Prakash, A; Singh, S | 1 |
| George, O; Le Moal, M; Mayo, W; Piazza, PV; Vallée, M; Vitiello, S | 1 |
| Adams, S; Hassell, J; Hiegel, C; Miryala, CS; Uphouse, L; Uzor, N | 1 |
| Chopde, CT; Thakre, PP; Tundulwar, MR; Ugale, RR | 1 |
1 review(s) available for pregnanolone and indomethacin
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
1 trial(s) available for pregnanolone and indomethacin
| Article | Year |
|---|---|
Effects of fluoxetine, indomethacine and placebo on 3 alpha, 5 alpha tetrahydroprogesterone (THP) plasma levels in uncomplicated alcohol withdrawal.
Topics: Adult; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Ethanol; Fluoxetine; gamma-Aminobutyric Acid; Humans; Indomethacin; Male; Pregnanolone; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome | 2000 |
16 other study(ies) available for pregnanolone and indomethacin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Characterization of the purified pituitary cytosolic NADPH:5 alpha-dihydroprogesterone 3 alpha-hydroxysteroid oxidoreductase.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Alcohol Oxidoreductases; Animals; Cytosol; Female; Indomethacin; Medroxyprogesterone; Mercaptoethanol; NADP; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pituitary Gland; Pregnanediones; Pregnanolone; Progesterone; Rats; Substrate Specificity | 1990 |
Progesterone withdrawal decreases latency to and increases duration of electrified prod burial: a possible rat model of PMS anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Disease Models, Animal; Electroshock; Estradiol; Female; Indomethacin; Pregnanolone; Premenstrual Syndrome; Progesterone; Rats; Substance Withdrawal Syndrome | 1993 |
GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.
Topics: Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Carbolines; Female; gamma-Aminobutyric Acid; Hippocampus; Indomethacin; Lorazepam; Oligonucleotides, Antisense; Patch-Clamp Techniques; Pregnanolone; Premenstrual Syndrome; Progesterone; Pyramidal Cells; Rats; Receptors, GABA-A; RNA, Messenger; Transcription, Genetic | 1998 |
Effects of progesterone or neuroactive steroid?
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Brain; Cyclooxygenase Inhibitors; Ethanol; Female; Indomethacin; Pregnanolone; Progesterone; Rats; Receptors, GABA-A | 1998 |
Indomethacin inhibits lordosis induced by ring A-reduced progestins: possible role of 3alpha-oxoreduction in progestin-facilitated lordosis.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Brain; Brain Chemistry; Cyclooxygenase Inhibitors; Estrus; Female; Grooming; Indomethacin; Male; Oxidation-Reduction; Posture; Pregnanolone; Progestins; Rats; Rats, Wistar; Receptors, Progesterone; Sexual Behavior, Animal | 1999 |
Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.
Topics: Animals; Behavior, Animal; Bicuculline; Brain Chemistry; Central Nervous System Depressants; Cerebral Cortex; Convulsants; Cyclooxygenase Inhibitors; Dihydrotestosterone; Electrophysiology; Enzyme Inhibitors; Epilepsy; Ethanol; Finasteride; Indomethacin; Male; Neuroprotective Agents; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2000 |
Progesterone prevents estradiol-induced dendritic spine formation in cultured hippocampal neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Size; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dendrites; Drug Interactions; Estradiol; Fetus; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Indomethacin; Microscopy, Electron; Mifepristone; Neuronal Plasticity; Patch-Clamp Techniques; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Signal Transduction | 2000 |
Cataleptic effect of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice: modulation by serotonergic agents.
Topics: 5,7-Dihydroxytryptamine; Animals; Bicuculline; Catalepsy; Drug Synergism; Enzyme Inhibitors; GABA Antagonists; Indoleacetic Acids; Indomethacin; Male; Mice; Pregnanolone; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Synaptic Transmission | 2001 |
Ventral tegmental area infusions of inhibitors of the biosynthesis and metabolism of 3alpha,5alpha-THP attenuate lordosis of hormone-primed and behavioural oestrous rats and hamsters.
Topics: Androstenols; Animals; Cricetinae; Estradiol; Estrus; Female; Finasteride; Gonadal Steroid Hormones; Indomethacin; Injections; Pregnanolone; Progesterone; Rats; Rats, Long-Evans; Sexual Behavior, Animal; Tegmentum Mesencephali | 2001 |
Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Brain; Brain Chemistry; Desoxycorticosterone; Hepatic Encephalopathy; Humans; Indomethacin; Male; Molecular Structure; Motor Activity; Portacaval Shunt, Surgical; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids | 2008 |
Increasing 3alpha,5alpha-THP following inhibition of neurosteroid biosynthesis in the ventral tegmental area reinstates anti-anxiety, social, and sexual behavior of naturally receptive rats.
Topics: Animals; Anxiety; Behavior, Animal; Exploratory Behavior; Female; Indoleacetic Acids; Indomethacin; Isoquinolines; Pregnanolone; Rats; Rats, Long-Evans; Sexual Behavior, Animal; Social Behavior; Ventral Tegmental Area | 2009 |
Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice.
Topics: Animals; Convulsants; Disease Models, Animal; Electrophoresis, Agar Gel; Enzyme Inhibitors; Finasteride; Indomethacin; Male; Mice; Neurons; Picrotoxin; Pregnanolone; Seizures | 2010 |
Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats.
Topics: Aging; Animals; Behavior, Animal; Brain; Disease Models, Animal; Indomethacin; Male; Memory Disorders; Pregnanolone; Rats; Rats, Sprague-Dawley; Sleep Disorders, Circadian Rhythm; Steroids | 2010 |
Mechanisms responsible for progesterone's protection against lordosis-inhibiting effects of restraint II. Role of progesterone metabolites.
Topics: 5-alpha Reductase Inhibitors; Animals; Cyclooxygenase Inhibitors; Female; Finasteride; Indomethacin; Ovariectomy; Posture; Pregnanolone; Progestins; Rats; Rats, Inbred F344; Receptors, Progesterone; Restraint, Physical; Sexual Behavior, Animal | 2011 |
Neurosteroid allopregnanolone attenuates development of nicotine withdrawal behavior in mice.
Topics: Animals; Anxiety; Finasteride; Indomethacin; Male; Maze Learning; Mice; Motor Activity; Neurotransmitter Agents; Nicotine; Pregnanolone; Progesterone; Substance Withdrawal Syndrome; Time Factors | 2013 |