Page last updated: 2024-08-23

pregnanolone and glutamic acid

pregnanolone has been researched along with glutamic acid in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's2 (8.33)18.2507
2000's6 (25.00)29.6817
2010's12 (50.00)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Smith, SS; Waterhouse, BD; Woodward, DJ1
Berger, TW; Grace, AA; Nisenbaum, ES1
Gjerstad, L; Ottersen, OP; Taubøll, E1
Jaako, K; Kaasik, A; Kalda, A; Zharkovsky, A1
Budziszewska, B; Jaworska-Feil, L; Lasoń, W; Leśkiewicz, M1
Dong, Y; Fu, YM; Hu, AQ; Lan, DM; Wang, ZM; Zheng, P; Zhu, YH1
Budziszewska, B; Jantas, D; Lason, W; Leskiewicz, M1
Agis-Balboa, RC; Nelson, M; Pibiri, F; Pinna, G1
Kaur, N; Kussius, CL; Popescu, GK1
Cabrera, R; Giuliani, FA; Laconi, M; Mohn, CE; Rettori, V; Yunes, R1
Cho, JH; Choi, IS; Jang, IS; Kim, BG; Lee, MG1
Ballabio, M; Di Cairano, ES; Magnaghi, V; Perego, C1
Agustí, A; Cauli, O; Felipo, V; González-Usano, A1
Salazar, P; Tapia, R1
Briz, V; Parkash, J; Prevot, V; Sánchez-Redondo, S; Suñol, C1
Buděšínský, M; Cerný, I; Krausová, B; Pouzar, V; Vyklický, L; Vyklický, V1
Akk, G; Bracamontes, JR; Li, P; Steinbach, JH1
Akaike, N; Fukuda, A; Iwata, S; Shin, MC; Wakita, M1
Bazzocchini, V; Cabrera, R; Casas, S; Escudero, C; Giuliani, FA; Laconi, MR; Yunes, R1
Bali, A; Jaggi, AS1
Cabrera, R; Estrella, CR; García, S; Lara, HE; Yunes, R1
Candelas Serra, M; Chodounska, H; Hajdukovic, D; Hrcka Krausova, B; Korinek, M; Krusek, J; Kudova, E; Smejkalova, T; Vyklicky, L1
Chern, CJ; Chern, CR; Chodounská, H; Kudová, E; Lauková, M; Schonwald, A; Shakarjian, MP; Velíšek, L; Velíšková, J1
Abramova, V; Balik, A; Bartunek, P; Bozikova, P; Cerny, J; Chodounska, H; Ciz, D; Dittert, I; Fili, K; Hill, M; Hrcka Krausova, B; Korinek, M; Kudova, E; Kysilov, B; Leal Alvarado, V; Maly, M; Martinovic, J; Smejkalova, T; Vales, K; Vyklicky, L; Vyklicky, V1

Reviews

2 review(s) available for pregnanolone and glutamic acid

ArticleYear
Modulation of allopregnanolone on excitatory transmitters release from single glutamatergic terminal.
    Brain research bulletin, 2013, Volume: 93

    Topics: Animals; Animals, Newborn; Bicuculline; Biophysics; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glutamic Acid; Muscimol; Patch-Clamp Techniques; Potassium Channel Blockers; Pregnanolone; Presynaptic Terminals; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Tetraethylammonium; Valine

2013
Multifunctional aspects of allopregnanolone in stress and related disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Jan-03, Volume: 48

    Topics: Anxiety; Brain-Derived Neurotrophic Factor; Calcium Channels; Depression; Dopamine; Glutamic Acid; Humans; Oxytocin; Pregnanolone; Receptors, GABA-A; Stress, Psychological

2014

Other Studies

22 other study(ies) available for pregnanolone and glutamic acid

ArticleYear
Locally applied progesterone metabolites alter neuronal responsiveness in the cerebellum.
    Brain research bulletin, 1987, Volume: 18, Issue:6

    Topics: Animals; Drug Interactions; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Iontophoresis; Pregnanediol; Pregnanes; Pregnanolone; Purkinje Cells; Rats; Rats, Inbred Strains

1987
Depression of glutamatergic and GABAergic synaptic responses in striatal spiny neurons by stimulation of presynaptic GABAB receptors.
    Synapse (New York, N.Y.), 1993, Volume: 14, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Corpus Striatum; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Lidocaine; Male; Neurons; Pregnanolone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Sodium Channel Blockers; Synapses

1993
The progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one reduces K(+)-induced GABA and glutamate release from identified nerve terminals in rat hippocampus: a semiquantitative immunocytochemical study.
    Brain research, 1993, Oct-01, Volume: 623, Issue:2

    Topics: Animals; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Immunohistochemistry; Nerve Endings; Potassium; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley

1993
Dehydroepiandrosterone sulphate prevents oxygen-glucose deprivation-induced injury in cerebellar granule cell culture.
    Neuroscience, 2001, Volume: 102, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Count; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; GABA Modulators; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Pentobarbital; Picrotoxin; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Stereoisomerism

2001
Effect of allopregnanolone on d-[3H]-aspartate release and [3H]-glutamate uptake in the hippocampus of kainate-treated mice.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2002, Volume: 53, Issue:2

    Topics: Animals; D-Aspartic Acid; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; Pregnanolone; Tritium

2002
Inhibition of evoked glutamate release by neurosteroid allopregnanolone via inhibition of L-type calcium channels in rat medial prefrontal cortex.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:7

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Postsynaptic Potentials; Glutamic Acid; Organ Culture Techniques; Prefrontal Cortex; Pregnanolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Synaptosomes; Veratridine

2007
Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59, Issue:3

    Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Death; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Excitatory Amino Acids; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phosphoinositide-3 Kinase Inhibitors; Pregnanolone; Pregnenolone; Reactive Oxygen Species; Staurosporine; Steroids

2008
Enhanced fear responses in mice treated with anabolic androgenic steroids.
    Neuroreport, 2009, Apr-22, Volume: 20, Issue:6

    Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Amygdala; Anabolic Agents; Androgens; Animals; Conditioning, Psychological; Fear; Female; Fluoxetine; Gene Expression; Glutamic Acid; Hippocampus; Mice; Neurons; Prefrontal Cortex; Pregnanolone; RNA, Messenger; Steroids; Testosterone Propionate

2009
Pregnanolone sulfate promotes desensitization of activated NMDA receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, May-27, Volume: 29, Issue:21

    Topics: Aminosalicylic Acid; Animals; Cells, Cultured; Computer Simulation; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Frontal Lobe; Glutamic Acid; Humans; Ion Channel Gating; Membrane Potentials; Models, Biological; Neurons; Patch-Clamp Techniques; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Transfection

2009
Allopregnanolone induces LHRH and glutamate release through NMDA receptor modulation.
    Endocrine, 2011, Volume: 40, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Estrogen Replacement Therapy; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Models, Animal; N-Methylaspartate; Neurotransmitter Agents; Ovariectomy; Pregnanolone; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2011
Modulation of presynaptic GABA(A) receptors by endogenous neurosteroids.
    British journal of pharmacology, 2011, Volume: 164, Issue:6

    Topics: Animals; Dentate Gyrus; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABAergic Neurons; gamma-Cyclodextrins; Glutamic Acid; In Vitro Techniques; Patch-Clamp Techniques; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission

2011
Neurosteroid allopregnanolone regulates EAAC1-mediated glutamate uptake and triggers actin changes in Schwann cells.
    Journal of cellular physiology, 2012, Volume: 227, Issue:4

    Topics: Actins; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport, Active; Excitatory Amino Acid Transporter 3; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Models, Neurological; Pregnanolone; Rats; RNA, Messenger; Schwann Cells; Up-Regulation

2012
Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo.
    Neuroscience, 2011, Sep-08, Volume: 190

    Topics: Animals; Cerebellum; Cyclic GMP; Dehydroepiandrosterone; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2011
Allopregnanolone potentiates the glutamate-mediated seizures induced by 4-aminopyridine in rat hippocampus in vivo.
    Neurochemical research, 2012, Volume: 37, Issue:3

    Topics: 4-Aminopyridine; Animals; Drug Interactions; Electroencephalography; Glutamic Acid; Hippocampus; Male; Pregnanolone; Rats; Rats, Wistar; Seizures

2012
Allopregnanolone prevents dieldrin-induced NMDA receptor internalization and neurotoxicity by preserving GABA(A) receptor function.
    Endocrinology, 2012, Volume: 153, Issue:2

    Topics: Anesthetics; Animals; Cell Membrane; Cerebral Cortex; Dieldrin; Disks Large Homolog 4 Protein; Embryo, Mammalian; Endocrine Disruptors; Estradiol; Female; Gene Expression Regulation; Glutamic Acid; Guanylate Kinases; Membrane Proteins; Mice; Neurons; Pregnancy; Pregnanolone; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2012
Neuroactive steroids with perfluorobenzoyl group.
    Steroids, 2012, Volume: 77, Issue:12

    Topics: Azides; Fluorocarbons; Glutamic Acid; HEK293 Cells; Humans; Pregnanes; Pregnanolone; Receptors, N-Methyl-D-Aspartate; Steroids

2012
A neurosteroid potentiation site can be moved among GABAA receptor subunits.
    The Journal of physiology, 2012, Nov-15, Volume: 590, Issue:22

    Topics: Action Potentials; Amino Acid Sequence; Anesthetics; Animals; Binding Sites; gamma-Aminobutyric Acid; Glutamic Acid; HEK293 Cells; Humans; Molecular Sequence Data; Mutation, Missense; Pregnanolone; Protein Subunits; Rats; Receptors, GABA-A

2012
Allopregnanolone and puberty: modulatory effect on glutamate and GABA release and expression of 3α-hydroxysteroid oxidoreductase in the hypothalamus of female rats.
    Neuroscience, 2013, Jul-23, Volume: 243

    Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Animals; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Neurotransmitter Agents; Pregnanolone; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sexual Maturation

2013
Postnatal administration of allopregnanolone modifies glutamate release but not BDNF content in striatum samples of rats prenatally exposed to ethanol.
    BioMed research international, 2015, Volume: 2015

    Topics: Alcohol Drinking; Animals; Brain-Derived Neurotrophic Factor; Corpus Striatum; Ethanol; Female; Glutamic Acid; Male; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2015
Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms.
    British journal of pharmacology, 2021, Volume: 178, Issue:19

    Topics: Animals; Glutamic Acid; HEK293 Cells; Humans; Neurosteroids; Pregnanolone; Rats; Sulfates

2021
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnanolone; Pyrrolidonecarboxylic Acid; Rodentia; Spasm; Spasms, Infantile

2023
Effects of Pregnanolone Glutamate and Its Metabolites on GABA
    ACS chemical neuroscience, 2023, 05-17, Volume: 14, Issue:10

    Topics: Animals; Esters; gamma-Aminobutyric Acid; Glutamic Acid; Pregnanolone; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Zebrafish

2023