pregnanolone has been researched along with gaboxadol in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alkana, RL; Bolger, MB; Brinton, RD; Davies, DL; Finn, DA | 1 |
| Beyer, C; García-Juárez, M; González-Flores, O; González-Mariscal, G; Lima-Hernández, FJ; Sánchez, N | 1 |
| France, CP; McMahon, LR | 1 |
| Gong, QH; Shen, H; Smith, SS; Yuan, M | 1 |
| Biggio, F; Biggio, G; Busonero, F; Caria, S; Follesa, P; Gorini, G; Mostallino, MC; Mura, ML; Murru, L; Sanna, E | 1 |
| Gartside, SE; Ingram, CD; Judge, SJ; Kaura, V; Young, AH | 1 |
| Darbra, S; Pallarès, M | 1 |
| Chesnoy-Marchais, D | 1 |
| Finn, DA; Ford, MM; Fretwell, AM; Ramaker, MJ | 1 |
| Asiedu, MN; Kaila, K; Malan, TP; Mejia, G; Ossipov, MK; Price, TJ | 1 |
| Finn, DA; Ford, MM; Ramaker, MJ; Strong, MN | 1 |
| France, CP; Gerak, LR | 1 |
| Gong, QH; Smith, SS | 1 |
| Finn, DA; Ford, MM; Phillips, TJ; Ramaker, MJ | 1 |
| Finn, DA; Ford, MM; Phillips, TJ; Ramaker, MJ; Strong-Kaufman, MN | 1 |
| Gerak, LR; Ibarra, MH; Pressly, JD; Smith, KR; Zanettini, C | 1 |
| Afroz, S; Shen, H; Smith, SS | 1 |
17 other study(ies) available for pregnanolone and gaboxadol
| Article | Year |
|---|---|
In vivo and in vitro hyperbaric studies in mice suggest novel sites of action for ethanol.
Topics: Allosteric Regulation; Analysis of Variance; Animals; Diazepam; Ethanol; Flunitrazepam; GABA Modulators; Hyperbaric Oxygenation; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Pregnanolone; Receptors, GABA-A | 1999 |
Estradiol and testosterone modulate the anesthetic action of the GABA-A agonist THIP, but not of the neurosteroid 3alpha,5beta-pregnanolone in the rat.
Topics: Anesthesia; Anesthetics; Animals; Drug Interactions; Estradiol; Female; GABA Agonists; Isoxazoles; Male; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Reflex; Sex Characteristics; Testosterone | 2004 |
Combined discriminative stimulus effects of midazolam with other positive GABAA modulators and GABAA receptor agonists in rhesus monkeys.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethanol; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Injections, Subcutaneous; Isoxazoles; Macaca mulatta; Male; Midazolam; Pentobarbital; Pregnanolone; Receptors, GABA-A; Time Factors; Triazolam; Women | 2005 |
Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: pharmacological and behavioral effects.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Bicuculline; Blotting, Western; Cell Separation; Electrophysiology; Estradiol; Female; GABA Agonists; GABA Antagonists; Hippocampus; Homeostasis; In Vitro Techniques; Isoxazoles; Lanthanum; Lorazepam; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pregnanolone; Rats; Rats, Long-Evans; Receptors, GABA-A; Steroids | 2005 |
Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons.
Topics: Anesthetics; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Central Nervous System Depressants; Cerebellum; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Ethanol; GABA Agonists; Gene Expression Regulation; Hippocampus; Immunohistochemistry; Isoxazoles; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pregnanolone; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2005 |
The progesterone metabolite allopregnanolone potentiates GABA(A) receptor-mediated inhibition of 5-HT neuronal activity.
Topics: Action Potentials; Analysis of Variance; Anesthetics; Animals; Drug Interactions; Female; GABA Agonists; In Vitro Techniques; Isoxazoles; Muscimol; Neural Inhibition; Neurons; Pregnanolone; Progesterone; Raphe Nuclei; Rats; Receptors, GABA-A; Serotonin; Time Factors | 2007 |
Neonatal allopregnanolone increases novelty-directed locomotion and disrupts behavioural responses to GABA(A) receptor modulators in adulthood.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Flumazenil; GABA Modulators; Isoxazoles; Lorazepam; Male; Maze Learning; Midazolam; Motor Activity; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A | 2009 |
Progesterone and allopregnanolone enhance the miniature synaptic release of glycine in the rat hypoglossal nucleus.
Topics: Action Potentials; Anesthetics; Animals; Animals, Newborn; Biophysics; Electric Stimulation; GABA Agonists; Glycine; Hypoglossal Nerve; Isoxazoles; Medulla Oblongata; Motor Neurons; Patch-Clamp Techniques; Pregnanolone; Progesterone; Progestins; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 2009 |
Alteration of ethanol drinking in mice via modulation of the GABA(A) receptor with ganaxolone, finasteride, and gaboxadol.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Finasteride; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Models, Animal; Pregnanolone; Receptors, GABA-A | 2011 |
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice.
Topics: Analgesia; Analgesics; Animals; Benzodiazepines; Chlorides; GABA-A Receptor Agonists; Isoxazoles; K Cl- Cotransporters; Male; Mice; Mice, Inbred ICR; Muscimol; Neuralgia; Peripheral Nerve Injuries; Pregnanolone; Receptors, GABA-A; Sciatic Nerve; Symporters | 2012 |
Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drugs, Investigational; Ethanol; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Nootropic Agents; Pregnanolone; Protein Subunits; Receptors, GABA-A; Reinforcement, Psychology; Self Administration; Time Factors | 2012 |
Discriminative stimulus effects of pregnanolone in rhesus monkeys.
Topics: Animals; Conditioning, Operant; Data Interpretation, Statistical; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flumazenil; Flunitrazepam; GABA Modulators; Gonadal Steroid Hormones; Hypnotics and Sedatives; Isoxazoles; Macaca mulatta; Male; Midazolam; Pregnanolone; Receptors, GABA-A; Reinforcement Schedule | 2014 |
Characterization of neurosteroid effects on hyperpolarizing current at α4β2δ GABAA receptors.
Topics: Amino Acid Sequence; Cell Polarity; DNA, Complementary; GABA Agonists; HEK293 Cells; Humans; Isoxazoles; Molecular Sequence Data; Mutant Chimeric Proteins; Neurotransmitter Agents; Patch-Clamp Techniques; Pregnanolone; Receptors, GABA-A; Transfection | 2014 |
Differences in the reinstatement of ethanol seeking with ganaxolone and gaboxadol.
Topics: Animals; Behavior, Animal; Ethanol; Extinction, Psychological; GABA Agonists; Isoxazoles; Male; Mice, Inbred C57BL; Pregnanolone; Receptors, GABA-A | 2014 |
Effect of nucleus accumbens shell infusions of ganaxolone or gaboxadol on ethanol consumption in mice.
Topics: Alcohol Drinking; Animals; Ethanol; GABA-A Receptor Agonists; Infusions, Intraventricular; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Pregnanolone; Receptors, GABA-A; Treatment Outcome | 2015 |
Comparing the discriminative stimulus effects of modulators of GABAA receptors containing α4-δ subunits with those of gaboxadol in rats.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Flumazenil; GABA Agonists; GABA Modulators; Isoxazoles; Male; Midazolam; Pregnanolone; Protein Subunits; Rats; Receptors, GABA-A | 2016 |
α4βδ GABA
Topics: Aging; Animals; CA1 Region, Hippocampal; Dendritic Spines; Female; GABA-A Receptor Agonists; Isoxazoles; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Pregnanolone; Receptors, GABA-A; Spatial Learning | 2017 |