pregnanolone has been researched along with flunitrazepam in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 27 (58.70) | 18.2507 |
| 2000's | 14 (30.43) | 29.6817 |
| 2010's | 5 (10.87) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Prince, RJ; Simmonds, MA | 2 |
| Costa, E; Paul, SM; Pritchett, DB; Puia, G; Purdy, RH; Santi, MR; Seeburg, PH; Vicini, S | 1 |
| Akwa, Y; Baulieu, EE; el-Etr, M; Fiddes, RJ; Robel, P | 1 |
| Moore, FL; Murray, TF; Orchinik, M | 1 |
| Belfiore, MS; Giusti, L; Lucacchini, A; Martini, C | 1 |
| Farb, DH; Friedman, L; Gibbs, TT | 1 |
| Canonaco, M; Carelli, A; Maggi, A | 1 |
| Devaud, LL; Morrow, AL; Paul, SM; Purdy, RH | 1 |
| Bain, C; Garrett, EM; Hadingham, KL; Heavens, RP; Sirinathsinghji, DJ; Wafford, KA; Whiting, PJ | 1 |
| Bennett, PJ; Simmonds, MA | 1 |
| Fiszer de Plazas, S; Gravielle, MC; Pignataro, L | 1 |
| Simmonds, MA; Zhong, Y | 1 |
| Fiszer de Plazas, S; Pignataro, L | 2 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Belelli, D; Bolger, MB; Carter, RB; Gee, KW; Hawkinson, JE; Lambert, JJ; Lan, NC; Mirsadeghi, S; Tahir, SH; White, HS; Wieland, S; Wolf, HH; Wood, PL | 1 |
| Ford, E; Hagan, RM; Marshall, FH; Mullings, J; Oakley, NR; Stratton, SC; Worton, SP | 1 |
| Barron, KW; Briscoe, RJ; Garrett, KM; Heesch, CM | 1 |
| Belluzzi, J; Gee, KW; Hawkinson, JE; Hogenkamp, D; Lan, NC; Stein, L; Upasani, R; Wieland, S; Wood, PL | 1 |
| Brozowski, S; Chuang, L; Hadingham, K; Harris, RA; Valenzuela, CF; Whiting, PJ | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Acosta-Burruel, M; Carter, RB; Chen, JS; Drewe, JA; Hawkinson, JE; Hogenkamp, DJ; Lan, NC; Upasani, RB; Whittemore, ER; Woodward, RM; Yang, KC | 1 |
| Bailey, CD; Brien, JF; Reynolds, JN | 1 |
| Maitra, R; Reynolds, JN | 1 |
| Alkana, RL; Bolger, MB; Brinton, RD; Davies, DL; Finn, DA | 1 |
| Chistina Grobin, A; Devaud, LL; Inglefield, JR; Morrow, AL; Schwartz-Bloom, RD | 1 |
| Barbaccia, ML; Biggio, G; Concas, A; Follesa, P; Purdy, RH | 1 |
| Bargas, J; Brailowsky, S; Calixto, E; Casasola, C; López-Colomé, AM; Montiel, T | 1 |
| Findlay, GS; Harris, RA; Harrison, NL; Ueno, S | 1 |
| Alkana, RL; Bolger, MB; Davies, DL; McCauley, LD | 1 |
| Simmonds, MA; Sooksawate, T | 1 |
| Grobin, AC; Morrow, AL | 1 |
| Lu, YQ; Yu, R | 1 |
| Bäckström, T; Lundgren, P; Strömberg, J; Wang, M | 1 |
| Choi, HC; Ha, JH; Kang, BJ; Kang, HG; Kim, JY; Lee, JB; Lee, JT; Lee, KY; Park, YH | 1 |
| Brien, JF; Dringenberg, HC; Iqbal, U; Reynolds, JN | 1 |
| Ahboucha, S; Butterworth, RF; Mamer, O; Pomier-Layrargues, G | 1 |
| Betts, BA; Gill, N; Griffith, TN; Hall, AC; Humbert, DJ; Jenkins, A; Kelly, EW; Kotey, FO; Rowan, KC; Veneskey, KC; Watt, EE | 1 |
| Gerak, LR | 1 |
| Bai, X; Gerak, LR | 1 |
| Amato, RJ; Moerschbaecher, JM; Winsauer, PJ | 1 |
| France, CP; Gerak, LR | 2 |
| Burton, G; Coirini, H; Ghini, AA; Kruse, MS; Rey, M; Veleiro, AS | 1 |
1 review(s) available for pregnanolone and flunitrazepam
| Article | Year |
|---|---|
Neuroactive steroid modulators of the stress response.
Topics: Adrenalectomy; Alcoholism; Animals; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Estrus; Female; Flunitrazepam; Hypothalamo-Hypophyseal System; Male; Menstruation; Pregnancy; Pregnanolone; Pregnenolone; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Stress, Physiological | 1995 |
45 other study(ies) available for pregnanolone and flunitrazepam
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
5 beta-pregnan-3 beta-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complex.
Topics: Animals; Benzodiazepines; Binding, Competitive; Flunitrazepam; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pentobarbital; Pregnanolone; Rats; Rats, Inbred Strains | 1992 |
Neurosteroids act on recombinant human GABAA receptors.
Topics: Benzodiazepines; Cell Line, Transformed; Cell Membrane Permeability; Chlorides; Desoxycorticosterone; Electric Conductivity; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Membrane Potentials; Pentobarbital; Pregnanolone; Receptors, GABA-A; Recombinant Proteins; Transfection | 1990 |
A progesterone metabolite stimulates the release of gonadotropin-releasing hormone from GT1-1 hypothalamic neurons via the gamma-aminobutyric acid type A receptor.
Topics: Animals; Anti-Anxiety Agents; Brain; Cell Line; Dose-Response Relationship, Drug; Flunitrazepam; Gene Expression; Gonadotropin-Releasing Hormone; Hypothalamus; Kinetics; Muscimol; Neurons; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; RNA, Messenger | 1995 |
Steroid modulation of GABAA receptors in an amphibian brain.
Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Convulsants; Corticosterone; Flunitrazepam; Kinetics; Male; Mammals; Neurons; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Salamandridae; Species Specificity; Steroids; Sulfur Radioisotopes; Synaptosomes; Tritium | 1994 |
Differential antagonism by epipregnanolone of alphaxalone and pregnanolone potentiation of [3H]flunitrazepam binding suggests more than one class of binding site for steroids at GABAA receptors.
Topics: Anesthetics; Animals; Brain; Flunitrazepam; In Vitro Techniques; Male; Membranes; Pregnanediones; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
3 alpha-hydroxy-5 alpha-pregnan-20-one modulation of solubilized GABA/benzodiazepine receptor complex.
Topics: Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; Pregnanolone; Radioligand Assay; Rats; Receptors, GABA-A; Solubility | 1993 |
Gamma-aminobutyric acidA receptor regulation: chronic treatment with pregnanolone uncouples allosteric interactions between steroid and benzodiazepine recognition sites.
Topics: Allosteric Site; Animals; Brain; Cells, Cultured; Chick Embryo; Flunitrazepam; Pregnanolone; Radioligand Assay; Receptors, GABA-A; Receptors, Steroid | 1993 |
Steroid hormones and receptors of the GABAA supramolecular complex. I. Benzodiazepine receptor level changes in some extrahypothalamic brain areas of the female rat following sex steroid treatment.
Topics: Animals; Autoradiography; Binding Sites; Estradiol; Female; Flunitrazepam; In Vitro Techniques; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA; Tissue Distribution | 1993 |
Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.
Topics: Amino Acid Sequence; Animals; Antisense Elements (Genetics); Autoradiography; Base Sequence; Cerebellar Cortex; Cloning, Molecular; DNA Primers; DNA, Complementary; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; In Situ Hybridization; Kinetics; L Cells; Ligands; Macromolecular Substances; Membrane Potentials; Mice; Molecular Sequence Data; Oocytes; Pentobarbital; Polymerase Chain Reaction; Pregnanolone; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Transfection; Xenopus laevis | 1996 |
The influence of membrane cholesterol on the GABAA receptor.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Cholesterol; Dose-Response Relationship, Drug; Drug Interactions; Flunitrazepam; GABA Agents; Liposomes; Male; Muscimol; Pregnanolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1996 |
Neurosteroid modulation of the benzodiazepine receptor in developing chick optic lobe.
Topics: Animals; Anti-Anxiety Agents; Chick Embryo; Chickens; Desoxycorticosterone; Dose-Response Relationship, Drug; Flunitrazepam; Isomerism; Kinetics; Neuroprotective Agents; Pregnanolone; Receptors, GABA-A; Tectum Mesencephali | 1996 |
Pharmacological characterisation of multiple components in the enhancement by pregnanolone and propofol of [3H]flunitrazepam binding to GABAA receptors.
Topics: Anesthetics, Intravenous; Animals; Bicuculline; Flunitrazepam; GABA Agonists; GABA Modulators; In Vitro Techniques; Male; Muscimol; Pregnanolone; Progesterone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Membranes | 1996 |
Epipregnanolone acts as a partial agonist on a common neurosteroid modulatory site of the GABA(A) receptor complex in avian CNS.
Topics: Animals; Chickens; Drug Synergism; Flunitrazepam; GABA Agonists; Pregnanediones; Pregnanolone; Receptors, GABA; Tritium | 1997 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor.
Topics: Animals; Anticonvulsants; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; GABA Modulators; Humans; In Vitro Techniques; Kindling, Neurologic; Mice; Pregnanolone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Seizures | 1997 |
Development of tolerance in mice to the sedative effects of the neuroactive steroid minaxolone following chronic exposure.
Topics: Anesthetics; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Flunitrazepam; GABA Agonists; GABA Modulators; GABA-A Receptor Antagonists; Hypnotics and Sedatives; In Vitro Techniques; Male; Membranes; Mice; Mice, Inbred Strains; Motor Activity; Muscimol; Pregnanolone; Radioligand Assay; Rats; Temazepam | 1997 |
Neurosteroid modulation of [3H]flunitrazepam binding in the medulla: an autoradiographic study.
Topics: Animals; Autoradiography; Female; Flunitrazepam; GABA Modulators; Medulla Oblongata; Pregnanolone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tritium | 1997 |
Anxiolytic and anticonvulsant activity of a synthetic neuroactive steroid Co 3-0593.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Binding, Competitive; Cerebral Cortex; Flunitrazepam; GABA Agonists; GABA Modulators; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Mice; Muscimol; Phenolsulfonphthalein; Postural Balance; Pregnanolone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1997 |
Adaptation of gamma-aminobutyric acid type A receptors to alcohol exposure: studies with stably transfected cells.
Topics: Animals; Cells, Cultured; Drug Tolerance; Ethanol; Flunitrazepam; Humans; Mice; Muscimol; Pentobarbital; Pregnanolone; Protein Kinase C; Receptors, GABA-A; Transfection; Zinc | 1998 |
Chronic ethanol administration alters the modulatory effect of 5alpha-pregnan-3alpha-ol-20-one on the binding characteristics of various radioligands of GABAA receptors.
Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Ethanol; Flunitrazepam; GABA Agonists; GABA Modulators; Hippocampus; Male; Muscimol; Pregnanolone; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; GABA Modulators; Humans; Male; Mice; Muscimol; Pregnanolone; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus | 1998 |
Neurosteroid modulation of the GABAA receptor in the developing guinea pig cerebral cortex.
Topics: Animals; Benzodiazepines; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Female; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Guinea Pigs; Hypnotics and Sedatives; Male; Muscimol; Organ Size; Pregnanolone; Pyridines; Radioligand Assay; Receptors, GABA-A; Tritium; Zolpidem | 1999 |
Modulation of GABA(A) receptor function by neuroactive steroids: evidence for heterogeneity of steroid sensitivity of recombinant GABA(A) receptor isoforms.
Topics: Animals; Dose-Response Relationship, Drug; Female; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Humans; Pregnanediones; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Recombinant Proteins; Steroids; Xenopus laevis | 1998 |
In vivo and in vitro hyperbaric studies in mice suggest novel sites of action for ethanol.
Topics: Allosteric Regulation; Analysis of Variance; Animals; Diazepam; Ethanol; Flunitrazepam; GABA Modulators; Hyperbaric Oxygenation; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Pregnanolone; Receptors, GABA-A | 1999 |
Fluorescence imaging of GABAA receptor-mediated intracellular [Cl-] in P19-N cells reveals unique pharmacological properties.
Topics: Animals; Central Nervous System Depressants; Chlorides; Diazepam; DNA Primers; Ethanol; Flunitrazepam; Fluorescent Dyes; GABA Agonists; GABA Modulators; Gene Expression; Mice; Muscimol; Neoplastic Stem Cells; Neuroglia; Pentobarbital; Pregnanolone; Quinolinium Compounds; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 1999 |
Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.
Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Drug Interactions; Enzyme Inhibitors; Estrus; Female; Finasteride; Flunitrazepam; GABA Modulators; Gestational Age; Hippocampus; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Neocortical hyperexcitability after GABA withdrawal in vitro.
Topics: Animals; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Muscimol; Neocortex; Pregnanolone; Progesterone; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome; Synaptic Transmission | 2000 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors.
Topics: Allosteric Regulation; Animals; Bicuculline; Electric Conductivity; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Xenopus laevis | 2001 |
In ovo chronic neurosteroid treatment affects the function and allosteric interactions of GABA(A) receptor modulatory sites.
Topics: Allosteric Regulation; Animals; Chick Embryo; Chloride Channels; Chlorides; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Ion Transport; Nerve Tissue Proteins; Optic Lobe, Nonmammalian; Pregnanolone; Receptors, GABA-A; Signal Transduction; Specific Pathogen-Free Organisms; Synaptic Membranes; Synaptic Transmission | 2001 |
Pressure-sensitive and -insensitive coupling in gamma-aminobutyric acid(A) receptors.
Topics: Animals; Atmospheric Pressure; Chlorides; Chlorine; Flunitrazepam; GABA Modulators; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pentobarbital; Pregnanolone; Radioisotopes; Receptors, GABA-A; Synaptosomes | 2001 |
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.
Topics: Allosteric Regulation; Animals; Animals, Newborn; Anti-Anxiety Agents; Biological Transport; Cerebral Cortex; Chlorine; Desoxycorticosterone; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Labor, Obstetric; Male; Muscimol; Pregnancy; Pregnanolone; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sex Characteristics | 2001 |
Synergistic protection of allopregnanolone and phenobarbital against maximal electroshock seizures in mice.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Drug Synergism; Electroshock; Flunitrazepam; GABA Modulators; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Pregnanolone; Seizures | 2001 |
Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone).
Topics: Animals; Cerebral Cortex; Chlorides; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Osmolar Concentration; Pentobarbital; Pregnanolone; Rats; Rats, Wistar | 2003 |
Potentiated modulation of pregnolone on GABAA receptors in behaviorally stressed borderline-hypertensive rats.
Topics: Animals; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Flunitrazepam; GABA Modulators; Hypertension; Male; Pregnanolone; Rats; Rats, Inbred WKY; Receptors, GABA-A; Restraint, Physical; Species Specificity; Stress, Psychological; Synaptosomes | 2004 |
Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig.
Topics: Animals; Body Weight; Brain; Central Nervous System Depressants; Ethanol; Female; Flunitrazepam; GABA Modulators; Guinea Pigs; Hippocampus; Immunoblotting; Learning; Maze Learning; Motor Activity; Organ Size; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Radioligand Assay; Receptors, GABA-A; Space Perception | 2004 |
Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma.
Topics: Adult; Aged; Aged, 80 and over; Animals; Benzodiazepines; Brain Chemistry; Desoxycorticosterone; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Gas Chromatography-Mass Spectrometry; Hepatic Encephalopathy; Humans; In Vitro Techniques; Liver Cirrhosis; Male; Membranes; Middle Aged; Muscimol; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reference Standards | 2006 |
Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Cyclohexanols; Flumazenil; Flunitrazepam; Menthol; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus | 2008 |
Selective changes in sensitivity to benzodiazepines, and not other positive GABA(A) modulators, in rats receiving flunitrazepam chronically.
Topics: Animals; Benzodiazepines; Binding Sites; Dose-Response Relationship, Drug; Drug Tolerance; Flunitrazepam; Ketamine; Male; Midazolam; Morphine; Pentobarbital; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reinforcement Schedule; Substance-Related Disorders | 2009 |
Comparing the discriminative stimuli produced by either the neuroactive steroid pregnanolone or the benzodiazepine midazolam in rats.
Topics: Animals; Behavior, Animal; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; GABA Modulators; Male; Midazolam; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2011 |
Effects of pregnanolone and flunitrazepam on the retention of response sequences in rats.
Topics: Animals; Drug Combinations; Flunitrazepam; Male; Pregnanolone; Psychomotor Performance; Rats; Rats, Long-Evans; Reaction Time; Retention, Psychology | 2011 |
Quantitative analyses of antagonism: combinations of midazolam and either flunitrazepam or pregnanolone in rhesus monkeys discriminating midazolam.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; Flunitrazepam; Macaca mulatta; Midazolam; Pregnanolone; Receptors, GABA-A | 2012 |
Discriminative stimulus effects of pregnanolone in rhesus monkeys.
Topics: Animals; Conditioning, Operant; Data Interpretation, Statistical; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flumazenil; Flunitrazepam; GABA Modulators; Gonadal Steroid Hormones; Hypnotics and Sedatives; Isoxazoles; Macaca mulatta; Male; Midazolam; Pregnanolone; Receptors, GABA-A; Reinforcement Schedule | 2014 |
Effect of synthetic steroids on GABAA receptor binding in rat brain.
Topics: Animals; Autoradiography; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; GABA-A Receptor Agonists; Hippocampus; Male; Muscimol; Pregnanolone; Protein Binding; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Tritium | 2015 |