Page last updated: 2024-08-23

pregnanolone and etifoxine

pregnanolone has been researched along with etifoxine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Gillardin, JM; Neliat, G; Pansart, Y; Schlichter, R; Verleye, M1
Akwa, Y; Eychenne, B; Gillardin, JM; Ladurelle, N; Liere, P; Pianos, A; Schumacher, M; Verleye, M1
Chopde, CT; Hirani, K; Kokare, DM; Sharma, AN; Subhedar, NK; Ugale, RR1
Gillardin, JM; Heulard, I; Verleye, M1
Aouad, M; Goumon, Y; Petit-Demoulière, N; Poisbeau, P1
do Rego, JL; Vaudry, D; Vaudry, H1
Bahr, LM; Bauer, O; Dörfelt, A; Maurer, F; Melchner, D; Milenkovic, VM; Mühlberger, A; Nothdurfter, C; Reinders, J; Rupprecht, R; Weber, K; Wechsler, TF; Weigl, J; Wetter, TC; Wetzel, CH1

Trials

1 trial(s) available for pregnanolone and etifoxine

ArticleYear
Dissociation of endocrine responses to the Trier Social Stress Test in Virtual Reality (VR-TSST) by the benzodiazepine alprazolam and the translocator protein 18 kDa (TSPO) ligand etifoxine.
    Psychoneuroendocrinology, 2021, Volume: 124

    Topics: Adolescent; Adult; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Epinephrine; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Ligands; Male; Middle Aged; Oxazines; Pituitary-Adrenal System; Pregnanolone; Psychological Tests; Receptors, GABA; Receptors, GABA-A; Saliva; Stress, Psychological; Virtual Reality; Young Adult

2021

Other Studies

6 other study(ies) available for pregnanolone and etifoxine

ArticleYear
Functional modulation of gamma-aminobutyric acid(A) receptors by etifoxine and allopregnanolone in rodents.
    Neuroscience letters, 2001, Apr-06, Volume: 301, Issue:3

    Topics: Allosteric Site; Animals; Anticonvulsants; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Convulsants; Drug Interactions; GABA Antagonists; Male; Oxazines; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes

2001
The anxiolytic etifoxine activates the peripheral benzodiazepine receptor and increases the neurosteroid levels in rat brain.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Brain; Isoquinolines; Male; Oxazines; Pregnanolone; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Steroids

2005
Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats.
    Brain research, 2007, Dec-12, Volume: 1184

    Topics: Adrenalectomy; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Male; Maze Learning; Muscimol; Oxazines; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time

2007
Investigation of the anticonvulsive effect of acute immobilization stress in anxious Balb/cByJ mice using GABA A-related mechanistic probes.
    Psychopharmacology, 2008, Volume: 197, Issue:4

    Topics: Allosteric Regulation; Animals; Anxiety; Bridged Bicyclo Compounds, Heterocyclic; Clonazepam; Convulsants; Drug Interactions; Finasteride; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Oxazines; Picrotoxin; Pregnanolone; Progesterone; Receptors, GABA-A; Restraint, Physical; Seizures; Stress, Psychological

2008
Etifoxine stimulates allopregnanolone synthesis in the spinal cord to produce analgesia in experimental mononeuropathy.
    European journal of pain (London, England), 2014, Volume: 18, Issue:2

    Topics: Analgesia; Analgesics; Animals; Disease Models, Animal; Male; Mononeuropathies; Neuralgia; Oxazines; Pain Management; Pain Threshold; Pregnanolone; Rats; Rats, Sprague-Dawley; Spinal Cord

2014
The non-benzodiazepine anxiolytic drug etifoxine causes a rapid, receptor-independent stimulation of neurosteroid biosynthesis.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Animals; Anti-Anxiety Agents; Bicuculline; Complex Mixtures; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Gene Expression; Hypothalamus; Isoquinolines; Male; Neuropeptides; Oxazines; Peptide Fragments; Pregnanolone; Progesterone; Rana esculenta; Receptors, GABA-A; Tissue Culture Techniques

2015