Compounds > pregnanolone

Page last updated: 2024-08-23

pregnanolone and clozapine

pregnanolone has been researched along with clozapine in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jiang, A; LoGrasso, PV; Stearns, BA; Trauger, JW	1
Duncan, GE; Lieberman, JA; Marx, CE; Morrow, AL; VanDoren, MJ	1
Biggio, G; Fabrazzo, M; Maj, M; Monteleone, P; Pisu, MG; Serra, M; Tortorella, A	1
Gizerian, SS; Grobin, AC; Lieberman, JA; Moy, SS	1

Reviews

1 review(s) available for pregnanolone and clozapine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000

Other Studies

5 other study(ies) available for pregnanolone and clozapine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2). Biochemistry, 2002, Nov-12, Volume: 41, Issue:45 Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Carbamazepine; Catalysis; Clozapine; Enzyme Activation; Enzyme Inhibitors; Fluoxetine; Flurbiprofen; Humans; Hydroxysteroid Dehydrogenases; Kinetics; Oxidation-Reduction; Pregnanediones; Pregnanolone; Recombinant Fusion Proteins; Selective Serotonin Reuptake Inhibitors; Substrate Specificity; Ursodeoxycholic Acid	2002
Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:1 Topics: Adrenalectomy; Animals; Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Clozapine; Corticosterone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Haloperidol; Male; Olanzapine; Pirenzepine; Pregnanolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Risperidone	2003
Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study. Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:4 Topics: Adult; Analysis of Variance; Circadian Rhythm; Clozapine; Desoxycorticosterone; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pregnanolone; Prospective Studies; Schizophrenia	2004
Neonatal neurosteroid administration results in development-specific alterations in prepulse inhibition and locomotor activity: neurosteroids alter prepulse inhibition and locomotor activity. Psychopharmacology, 2006, Volume: 186, Issue:3 Topics: Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Clozapine; Female; GABA Antagonists; Male; Motor Activity; Pregnanolone; Rats; Rats, Sprague-Dawley; Reflex, Startle	2006