Page last updated: 2024-08-23

pregnanolone and brexanolone

pregnanolone has been researched along with brexanolone in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (4.84)	18.2507
2000's	9 (14.52)	29.6817
2010's	23 (37.10)	24.3611
2020's	27 (43.55)	2.80

Authors

Authors	Studies
Covey, DF; Han, M; Zorumski, CF	1
Acosta-Burruel, M; Alauddin, M; Bolger, MB; Gee, KW; Hawkinson, JE; Hogenkamp, DJ; Kimbrough, CL; Lan, NC; Tahir, SH; Upasani, RB; Whittemore, ER; Woodward, RM	1
Anderson, A; Boyd, AC; Byford, A; Campbell, AC; Gemmell, DK; Hamilton, NM; Hill, DR; Hill-Venning, C; Lambert, JJ; Maidment, MS; Marshall, RJ; May, V; Peters, JA; Rees, DC; Stevenson, D; Sundaram, H	1
Strassburg, CP; Tukey, RH	1
Benz, A; Coleman, M; Covey, DF; de La Cruz, MA; Evers, AS; Han, M; Hu, Y; Kumar, AS; Meadows, ES; Mennerick, S; Nathan, D; Tonnies, A; Zorumski, CF	1
Anderson, A; Boyd, AC; Clark, JK; Fielding, L; Gemmell, DK; Hamilton, NM; Maidment, MS; May, V; McGuire, R; McPhail, P; Sansbury, FH; Sundaram, H; Taylor, R	1
Benz, A; Covey, DF; Evers, AS; Jiang, X; Manion, BD; Mennerick, S; Rath, NP; Zorumski, CF	1
Benz, A; Covey, DF; Evers, AS; Manion, BD; Mennerick, S; Zeng, CM; Zorumski, CF	1
Babot, Z; Bujons, J; García, DA; Kasal, A; Kristofíková, Z; Matyás, L; Suñol, C	1
Benz, A; Covey, DF; DeKoster, GT; Evers, AS; Manion, BD; Mennerick, S; Rath, NP; Scaglione, JB; Taylor, A; Zorumski, CF	1
Benz, A; Cai, ZY; Covey, DF; Evers, AS; Katona, BW; Krishnan, K; Manion, BD; Mennerick, S; Taylor, A; Zorumski, CF	1
Alvarez, LD; Baggio, RF; Burton, G; Coirini, H; Edelsztein, VC; Garland, MT; Veleiro, AS	1
Colquhoun, H; Doherty, J; Hoffmann, E; Kanes, SJ; Meltzer-Brody, S; Raines, S; Rubinow, DR	1
Arnold, R; Colquhoun, H; Deligiannidis, KM; Doherty, J; Epperson, CN; Gunduz-Bruce, H; Hoffmann, E; Jonas, J; Kanes, S; Meltzer-Brody, S; Paul, S; Raines, S; Riesenberg, R; Rubinow, D; Schacterle, A	1
Clemson, C; Colquhoun, H; Deligiannidis, KM; Epperson, CN; Jonas, J; Kanes, S; Li, H; Meltzer-Brody, S; Riesenberg, R; Rubinow, DR; Sankoh, AJ; Schacterle, A	1
Mody, I	1
Deligiannidis, KM; Fersh, M; Frieder, A; Hainline, R	1
Scott, LJ	1
Gordon, JA	1
Ciolino, JD; Stika, CS; Wisner, KL	1
Tufts, JA	1
Colquhoun, H; Doherty, J; Kanes, S; Meltzer-Brody, S; Rubinow, DR	1
Parekh, J; Tang, GY	1
Lüscher, B; Möhler, H	1
Naguy, A	1
Cai, DB; Ning, YP; Peng, XJ; Sim, K; Ungvari, GS; Wang, G; Xiang, YT; Zheng, W	1
Fantasia, HC	1
Garland, S; Piszczatoski, C; Powell, JG; Preston, K	1
Leader, LD; O'Connell, M; VandenBerg, A	1
Bale, TL; Cole, AB; Morrison, KE; Thompson, SM	1
Cooper, MC; Eldar-Lissai, A; Hodgkins, P; Kilvert, HS; Roskell, NS	1
Arcara, A; Benfield, M; Brown, J; Crump, LH; Mospan, C; Mospan, G; Ramey, C; Yang, S	1
Cristea, IA; Naudet, F	1
Chuang, SH; Reddy, DS	1
Barron, RJ; Jarman, AF; MacLean, JV; McGregor, AJ; Wightman, RS	1
Cieri-Hutcherson, NE; Gosciak, MF; Hutcherson, TC	1
Daly, EJ; Drevets, WC; Fedgchin, M; Hough, D; Mathews, M; Popova, V; Singh, JB	1
Bond, JC; Chertavian, E; Cohen, JT; Eldar-Lissai, A; Gerbasi, ME; Hodgkins, P; Johnson, SJ; Meltzer-Brody, S	1
Jawaid, H; Khan, KS; Shabbir, O	1
Burval, J; Kerns, R; Reed, K	1
Deng, ZD; Henter, ID; Kadriu, B; Kraus, C; Lisanby, SH; Zarate, CA	1
Amodeo, G; Beccarini Crescenzi, B; Bolognesi, S; Cuomo, A; Fagiolini, A; Goracci, A; Laurenzi, PF; Neal, SM; Rossi, R; Santucci, A	1
Acaster, S; Bonthapally, V; Eldar-Lissai, A; Fridman, M; Gerbasi, ME; Hodgkins, P; Kanes, SJ; Meltzer-Brody, S	2
Kroska, EB; Stowe, ZN	1
Hussar, DA	1
Kleinman, RA; Schatzberg, AF	1
Nguyen, DR; Patatanian, E	1
Payne, JL	1
Ito, S; Rosen-Carole, C	1
Cornett, EM; Kaye, AD; Kaye, AM; Labbé, AM; Perkins, W; Rando, L; Urits, I; Viswanath, O	1
Cooke, E; Leader, LD; VandenBerg, A; Walkery, A	1
Balan, I; Boero, G; Morrow, AL	1
Battle, CL; Diaz, Z; Howard, MM	1
Li, F; Ma, J; Shi, L; Xu, L	1
Estes, E; Mbilinyi, RH; Reddy, DS	1

Reviews

15 review(s) available for pregnanolone and brexanolone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Pharmacotherapy of Postpartum Depression: Current Approaches and Novel Drug Development. CNS drugs, 2019, Volume: 33, Issue:3 Topics: Animals; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Drug Development; Female; GABA Modulators; Humans; Neurosteroids; Pregnanes; Pregnanolone; Pyrazoles; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration	2019
From Neurobiology to Novel Medications: A Principled Approach to Translation. The American journal of psychiatry, 2019, 06-01, Volume: 176, Issue:6 Topics: beta-Cyclodextrins; Brain; Depression, Postpartum; Drug Combinations; Drug Development; Drug Discovery; Female; Humans; Mental Disorders; Molecular Targeted Therapy; National Institute of Mental Health (U.S.); Neurobiology; Neurosteroids; Pregnanolone; Psychiatry; Psychotropic Drugs; Translational Research, Biomedical; United States	2019
Brexanolone, a neurosteroid antidepressant, vindicates the GABAergic deficit hypothesis of depression and may foster resilience. F1000Research, 2019, Volume: 8 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; Humans; Neurosteroids; Pregnanolone; Receptors, GABA-A	2019
Brexanolone for postpartum depression: A meta-analysis of randomized controlled studies. Psychiatry research, 2019, Volume: 279 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone; Randomized Controlled Trials as Topic; Treatment Outcome	2019
Brexanolone (Zulresso): Finally, an FDA-Approved Treatment for Postpartum Depression. The Annals of pharmacotherapy, 2020, Volume: 54, Issue:2 Topics: Antidepressive Agents; beta-Cyclodextrins; Clinical Trials as Topic; Depression, Postpartum; Drug Combinations; Female; Humans; Infusions, Intravenous; Pregnanolone; Quality of Life; Severity of Illness Index; Treatment Outcome; United States; United States Food and Drug Administration	2020
Brexanolone for Postpartum Depression: Clinical Evidence and Practical Considerations. Pharmacotherapy, 2019, Volume: 39, Issue:11 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; Humans; Pregnancy; Pregnanolone; Psychiatric Status Rating Scales; Severity of Illness Index	2019
Brexanolone for postpartum depression. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, Feb-19, Volume: 77, Issue:5 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Risk Evaluation and Mitigation; Severity of Illness Index	2020
Advances in treatment for postpartum major depressive disorder. Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:14 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Major; Drug Combinations; Drug Monitoring; Estrogens; Female; Humans; Oxytocin; Pregnanolone; Randomized Controlled Trials as Topic; Transcranial Magnetic Stimulation; Treatment Outcome; United States	2020
Postpartum Depression: Identification and Treatment in the Clinic Setting. Obstetrics and gynecology clinics of North America, 2020, Volume: 47, Issue:3 Topics: Adult; Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Infant; Mass Screening; Neurosteroids; Perinatal Care; Postpartum Period; Pregnancy; Pregnanolone; Prevalence; Psychiatric Status Rating Scales; Psychotherapy; Risk Factors; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires	2020
Brexanolone in Postpartum Depression: Journal of women's health (2002), 2021, Volume: 30, Issue:3 Topics: Adult; beta-Cyclodextrins; Clinical Decision-Making; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone; Treatment Outcome	2021
Brexanolone: A Novel Drug for the Treatment of Postpartum Depression. Journal of pharmacy practice, 2022, Volume: 35, Issue:3 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Unconsciousness	2022
Brexanolone to Treat Postpartum Depression in Adult Women. Psychopharmacology bulletin, 2021, 03-16, Volume: 51, Issue:2 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone	2021
Review of Allopregnanolone Agonist Therapy for the Treatment of Depressive Disorders. Drug design, development and therapy, 2021, Volume: 15 Topics: Antidepressive Agents; beta-Cyclodextrins; Bipolar Disorder; Depression, Postpartum; Depressive Disorder; Drug Combinations; Female; Humans; Pregnancy; Pregnanes; Pregnanolone; Psychiatric Status Rating Scales; Pyrazoles	2021
Preclinical and clinical pharmacology of brexanolone (allopregnanolone) for postpartum depression: a landmark journey from concept to clinic in neurosteroid replacement therapy. Psychopharmacology, 2023, Volume: 240, Issue:9 Topics: Antidepressive Agents; Depression, Postpartum; Female; Humans; Neurosteroids; Pregnanolone; Receptors, GABA-A	2023

Trials

4 trial(s) available for pregnanolone and brexanolone

Article	Year
Open-label, proof-of-concept study of brexanolone in the treatment of severe postpartum depression. Human psychopharmacology, 2017, Volume: 32, Issue:2 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Infusions, Intravenous; Pregnanolone; Proof of Concept Study; Treatment Outcome	2017
Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial. Lancet (London, England), 2017, 07-29, Volume: 390, Issue:10093 Topics: Adult; Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Infusions, Intravenous; Pregnanolone; Psychiatric Status Rating Scales; Treatment Outcome; Young Adult	2017
Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials. Lancet (London, England), 2018, 09-22, Volume: 392, Issue:10152 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; GABA Agonists; Humans; Injections, Intravenous; Pregnancy; Pregnancy Trimester, Third; Pregnanolone; Psychiatric Status Rating Scales; Receptors, GABA; Severity of Illness Index; Treatment Outcome; Young Adult	2018
Using Matching-Adjusted Indirect Comparisons and Network Meta-analyses to Compare Efficacy of Brexanolone Injection with Selective Serotonin Reuptake Inhibitors for Treating Postpartum Depression. CNS drugs, 2019, Volume: 33, Issue:10 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Male; Meta-Analysis as Topic; Network Meta-Analysis; Pregnanolone; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Serotonin	2019

Other Studies

43 other study(ies) available for pregnanolone and brexanolone

Article	Year
Neurosteroid analogues. 4. The effect of methyl substitution at the C-5 and C-10 positions of neurosteroids on electrophysiological activity at GABAA receptors. Journal of medicinal chemistry, 1996, Oct-11, Volume: 39, Issue:21 Topics: Animals; Cells, Cultured; Electrophysiology; HEPES; Hippocampus; Hydrogen-Ion Concentration; Methylation; Models, Molecular; Pregnanolone; Rats; Receptors, GABA; Tetrodotoxin	1996
Synthesis and in vitro activity of 3 beta-substituted-3 alpha-hydroxypregnan-20-ones: allosteric modulators of the GABAA receptor. Journal of medicinal chemistry, 1997, Jan-03, Volume: 40, Issue:1 Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Desoxycorticosterone; Electrophysiology; Female; In Vitro Techniques; Models, Molecular; Oocytes; Rats; Receptors, GABA-A; Xenopus	1997
Anesthetic activity of novel water-soluble 2 beta-morpholinyl steroids and their modulatory effects at GABAA receptors. Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11 Topics: Anesthesia; Anesthetics; Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Membrane; Chromaffin System; Electric Conductivity; Electrophysiology; Male; Mice; Molecular Structure; Morpholines; Pregnanediones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Solubility; Structure-Activity Relationship; Water	1997
Neurosteroid analogues. 8. Structure-activity studies of N-acylated 17a-aza-D-homosteroid analogues of the anesthetic steroids (3alpha, 5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. Journal of medicinal chemistry, 2000, Aug-24, Volume: 43, Issue:17 Topics: Anesthetics; Animals; Binding, Competitive; Brain; Crystallography, X-Ray; Electrophysiology; Homosteroids; In Vitro Techniques; Molecular Conformation; Oocytes; Pregnanes; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis	2000
Conformationally constrained anesthetic steroids that modulate GABA(A) receptors. Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22 Topics: Androstanols; Anesthetics; Animals; Brain; GABA Modulators; Hydrogen Bonding; In Vitro Techniques; Injections, Intravenous; Mice; Models, Molecular; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship	2000
Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. Journal of medicinal chemistry, 2003, Dec-04, Volume: 46, Issue:25 Topics: Anesthetics; Animals; Behavior, Animal; Cerebral Cortex; Electrophysiology; Female; GABA Modulators; In Vitro Techniques; Larva; Models, Molecular; Norsteroids; Oocytes; Patch-Clamp Techniques; Pregnanolone; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis	2003
Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8 Topics: Anesthetics; Animals; Binding Sites; Binding, Competitive; Brain; Electrophysiology; Female; GABA Modulators; In Vitro Techniques; Larva; Models, Molecular; Oocytes; Pregnanolone; Radioligand Assay; Rats; Receptors, GABA-A; Reflex; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis	2005
Activity of B-nor analogues of neurosteroids on the GABA(A) receptor in primary neuronal cultures. Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11 Topics: Animals; Anions; Cell Survival; Cells, Cultured; Chlorides; Computer Simulation; GABA Modulators; Male; Models, Molecular; Neocortex; Neurons; Pregnanolone; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Structure-Activity Relationship	2006
Neurosteroid analogues. 11. Alternative ring system scaffolds: gamma-aminobutyric acid receptor modulation and anesthetic actions of benz[f]indenes. Journal of medicinal chemistry, 2006, Jul-27, Volume: 49, Issue:15 Topics: Animals; Binding, Competitive; Brain; GABA Modulators; In Vitro Techniques; Indenes; Larva; Models, Molecular; Oocytes; Polycyclic Compounds; Radioligand Assay; Rats; Receptors, GABA-A; Stereoisomerism; Steroids; Structure-Activity Relationship; Xenopus laevis	2006
Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens. European journal of medicinal chemistry, 2008, Volume: 43, Issue:1 Topics: Androgens; Animals; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; GABA Modulators; Larva; Rats; Receptors, GABA-A; Stereoisomerism; Steroids	2008
Synthesis and GABA(A) receptor activity of oxygen-bridged neurosteroid analogs. Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7 Topics: Animals; Male; Models, Molecular; Molecular Structure; Neurons; Oxygen; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids	2008
GABA Cell, 2019, 01-10, Volume: 176, Issue:1-2 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Major; Drug Combinations; Female; Humans; Mood Disorders; Neurotransmitter Agents; Postpartum Period; Pregnancy; Pregnanolone; Prevalence; Receptors, GABA-A	2019
Brexanolone: First Global Approval. Drugs, 2019, Volume: 79, Issue:7 Topics: Administration, Intravenous; Adolescent; Adult; Allosteric Regulation; beta-Cyclodextrins; Depression, Postpartum; Drug Approval; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pregnanolone; Receptors, Steroid; Treatment Outcome; United States; United States Food and Drug Administration	2019
Brexanolone (Zulresso) for postpartum depression. The Medical letter on drugs and therapeutics, 2019, May-06, Volume: 61, Issue:1571 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Receptors, GABA-A	2019
Seeing the whole picture of postpartum depression. The lancet. Psychiatry, 2019, Volume: 6, Issue:7 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone	2019
The First Food and Drug Administration-Indicated Drug for Postpartum Depression-Brexanolone. JAMA psychiatry, 2019, 10-01, Volume: 76, Issue:10 Topics: beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Pregnanolone; United States; United States Food and Drug Administration	2019
Brexanolone injection for post-partum depression treatment. Lancet (London, England), 2019, 08-03, Volume: 394, Issue:10196 Topics: beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Pregnanolone	2019
Brexanolone injection for post-partum depression treatment - Authors' reply. Lancet (London, England), 2019, 08-03, Volume: 394, Issue:10196 Topics: beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Pregnanolone	2019
Brexanolone injection for post-partum depression treatment. Lancet (London, England), 2019, 08-03, Volume: 394, Issue:10196 Topics: beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Pregnanolone	2019
Brexanolone and postpartum depression: what does it have to do with GABA? Archives of women's mental health, 2019, Volume: 22, Issue:6 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; gamma-Aminobutyric Acid; Humans; Pregnanolone	2019
Brexanolone Is the First Drug Specifically for Postpartum Depression. Nursing for women's health, 2019, Volume: 23, Issue:5 Topics: Administration, Intravenous; Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Mothers; Postpartum Period; Pregnanolone; Selective Serotonin Reuptake Inhibitors	2019
Brexanolone for the treatment of patients with postpartum depression. Drugs of today (Barcelona, Spain : 1998), 2019, Volume: 55, Issue:9 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Approval; Drug Combinations; Female; Humans; Pregnanolone; United States; United States Food and Drug Administration	2019
Drug updates and approvals: 2019 in review. The Nurse practitioner, 2019, Volume: 44, Issue:12 Topics: Antibodies, Monoclonal; Azetidines; Benzyl Compounds; beta-Cyclodextrins; Carbamates; Clobetasol; Drug Approval; Drug Combinations; Formoterol Fumarate; Heterocyclic Compounds, 3-Ring; Humans; Lamivudine; Nicotinic Acids; Oxazines; Phenylalanine; Piperazines; Pregnanolone; Pyridones; Tropanes; United States; United States Food and Drug Administration	2019
US Food and Drug Administration approval of esketamine and brexanolone. The lancet. Psychiatry, 2019, Volume: 6, Issue:12 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Treatment-Resistant; Drug Combinations; Female; Humans; Ketamine; Pregnanolone; United States; United States Food and Drug Administration	2019
In with the new? The lancet. Psychiatry, 2019, Volume: 6, Issue:12 Topics: beta-Cyclodextrins; Drug Combinations; Ketamine; Pregnanolone; United States; United States Food and Drug Administration	2019
Isobolographic Analysis of Antiseizure Activity of the GABA Type A Receptor-Modulating Synthetic Neurosteroids Brexanolone and Ganaxolone with Tiagabine and Midazolam. The Journal of pharmacology and experimental therapeutics, 2020, Volume: 372, Issue:3 Topics: Animals; Anticonvulsants; beta-Cyclodextrins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Midazolam; Neurosteroids; Patch-Clamp Techniques; Pregnanolone; Receptors, GABA-A; Seizures; Tiagabine	2020
Brexanolone For Postpartum Depression: A Novel Approach and a Call for Comprehensive Postpartum Care. Clinical therapeutics, 2020, Volume: 42, Issue:1 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Neurosteroids; Postpartum Period; Pregnancy; Pregnanolone	2020
Approval of esketamine for treatment-resistant depression. The lancet. Psychiatry, 2020, Volume: 7, Issue:3 Topics: beta-Cyclodextrins; Depression; Depressive Disorder, Treatment-Resistant; Drug Combinations; Humans; Ketamine; Pregnanolone; United States; United States Food and Drug Administration	2020
Cost-Effectiveness of Brexanolone Versus Selective Serotonin Reuptake Inhibitors for the Treatment of Postpartum Depression in the United States. Journal of managed care & specialty pharmacy, 2020, Volume: 26, Issue:5 Topics: Adolescent; Adult; beta-Cyclodextrins; Cost-Benefit Analysis; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Prenatal Care; Psychometrics; Quality-Adjusted Life Years; Selective Serotonin Reuptake Inhibitors; United States; Young Adult	2020
Brexanolone Therapy for Postpartum Depression. JPMA. The Journal of the Pakistan Medical Association, 2020, Volume: 70, Issue:3 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; Humans; Pregnanolone	2020
Treating postpartum depression with brexanolone. Nursing, 2020, Volume: 50, Issue:5 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Approval; Drug Combinations; Female; Humans; Patient Education as Topic; Pregnanolone; Risk Assessment; United States; United States Food and Drug Administration	2020
Not So Fast: Recent Successes and Failures in Treating Depression. The Journal of clinical psychiatry, 2020, 05-26, Volume: 81, Issue:4 Topics: beta-Cyclodextrins; Depression; Drug Combinations; Excitatory Amino Acid Antagonists; GABA Modulators; Humans; Ketamine; Pregnanolone	2020
Associations between commonly used patient-reported outcome tools in postpartum depression clinical practice and the Hamilton Rating Scale for Depression. Archives of women's mental health, 2020, Volume: 23, Issue:5 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Mass Screening; Patient Health Questionnaire; Patient Reported Outcome Measures; Pregnanolone; Psychiatric Status Rating Scales; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires	2020
New drugs 2020, part 3. Nursing, 2020, Volume: 50, Issue:10 Topics: Aminophenols; Antibodies, Monoclonal, Humanized; Azabicyclo Compounds; Benzodioxoles; beta-Cyclodextrins; Cilastatin; Drug Approval; Drug Combinations; Ethinyl Estradiol; Genetic Vectors; Humans; Imipenem; Indoles; Nitroimidazoles; Pregnanolone; Pregnenediones; Pyrazoles; Pyridines; Pyrrolidines; Quinolones; Retinoids; United States; United States Food and Drug Administration	2020
Maternal and Newborn Safety During the Administration of Brexanolone: AWHONN Practice Brief Number 10. Journal of obstetric, gynecologic, and neonatal nursing : JOGNN, 2020, Volume: 49, Issue:6 Topics: Administration, Intravenous; Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Guidelines as Topic; Humans; Infant, Newborn; Maternal-Child Health Services; Patient Safety; Pregnanolone	2020
Maternal and Newborn Safety During the Administration of Brexanolone: AWHONN Practice Brief Number 10. Nursing for women's health, 2020, Volume: 24, Issue:6 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Health Personnel; Humans; Infant, Newborn; Infusions, Intravenous; Length of Stay; Mothers; Patient Safety; Pregnanolone; Severity of Illness Index; Workforce	2020
Understanding the Clinical Effects and Mechanisms of Action of Neurosteroids. The American journal of psychiatry, 2021, 03-01, Volume: 178, Issue:3 Topics: Antidepressive Agents; beta-Cyclodextrins; Depressive Disorder, Treatment-Resistant; Drug Combinations; Humans; Neurosteroids; Pregnanes; Pregnanolone; Pyrazoles	2021
Evaluating brexanolone for the treatment of postpartum depression. Expert opinion on pharmacotherapy, 2021, Volume: 22, Issue:8 Topics: beta-Cyclodextrins; Child; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone	2021
Using Brexanolone for Postpartum Depression Must Account for Lactation. Maternal and child health journal, 2021, Volume: 25, Issue:7 Topics: beta-Cyclodextrins; Breast Feeding; Depression, Postpartum; Drug Combinations; Female; Humans; Lactation; Milk, Human; Postpartum Period; Pregnanolone	2021
Mechanisms Underlying Recovery From Postpartum Depression Following Brexanolone Therapy. Biological psychiatry, 2022, 02-01, Volume: 91, Issue:3 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone	2022
Implementation of a Hospital-based Brexanolone Program. Journal of psychiatric practice, 2022, 09-01, Volume: 28, Issue:5 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Hospitals; Humans; Pregnancy; Pregnanolone	2022
Implementation of a Hospital-based Brexanolone Program: Erratum. Journal of psychiatric practice, 2023, 01-01, Volume: 29, Issue:1 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Female; Humans; Pregnanolone	2023
Design, synthesis and characterizations of prodrugs of brexanolone. Bioorganic & medicinal chemistry letters, 2023, 06-15, Volume: 90 Topics: beta-Cyclodextrins; Drug Combinations; Pregnanolone; Prodrugs; Receptors, GABA	2023