Page last updated: 2024-08-23

pregnanolone and androstane-3,17-diol

pregnanolone has been researched along with androstane-3,17-diol in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's2 (12.50)18.2507
2000's1 (6.25)29.6817
2010's7 (43.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Bell, JB1
Eckstein, B; Lerner, N2
Armstrong, DT; Hixon, JE; Kraemer, MA1
Lambert, JG; Schoonen, WG; Van Oordt, PG1
Banner, CD; Gustafsson, JA; MacDonald, PC; Strömstedt, M; Warner, M1
Bayon, LE; Frye, CA1
Paixão, JA; Pinto, RM; Salvador, JA1
Calza, L; Caruso, D; D'Intino, G; Garcia-Segura, LM; Giatti, S; Maschi, O; Melcangi, RC; Pesaresi, M1
Alward, SE; de Wit, H; Grant, KA; Leslie Morrow, A; O'Buckley, TK; Porcu, P; Song, SC1
Reddy, DS1
Carver, CM; Reddy, DS1
Eckert, A; Grimm, A; Lang, UE; Mensah-Nyagan, AG; Schmitt, K1
Brunton, PJ; Donadio, MV; Greenwood, M; Murphy, D; Russell, JA; Seckl, JR; Yao, ST1
Dichtel, LE; Eddy, KT; Klibanski, A; Lawson, EA; Meenaghan, E; Miller, KK; Nelson, M; Paskal, ML; Pinna, G; Rasmusson, AM; Schorr, M1
Caputi, V; Caruso, D; Cioffi, L; Diviccaro, S; Giatti, S; Lyte, JM; Melcangi, RC; O'Mahony, SM1

Reviews

2 review(s) available for pregnanolone and androstane-3,17-diol

ArticleYear
Neurosteroids: endogenous role in the human brain and therapeutic potentials.
    Progress in brain research, 2010, Volume: 186

    Topics: Androstane-3,17-diol; Anesthetics; Anxiety; Brain; Depression; Female; Humans; Male; Neurotransmitter Agents; Pregnanolone; Premenstrual Syndrome; Receptors, GABA-A; Seizures; Sex Characteristics; Stress, Physiological

2010
Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.
    Psychopharmacology, 2013, Volume: 230, Issue:2

    Topics: Allosteric Regulation; Androstane-3,17-diol; Animals; Brain; Desoxycorticosterone; Humans; Nerve Net; Neural Inhibition; Neuronal Plasticity; Neurotransmitter Agents; Pregnanolone; Receptors, GABA-A

2013

Other Studies

14 other study(ies) available for pregnanolone and androstane-3,17-diol

ArticleYear
Studies of in vitro steroid metabolism by testis tissue from 'complete' and 'incomplete' forms of testicular feminization.
    Clinical endocrinology, 1975, Volume: 4, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Androgen-Insensitivity Syndrome; Androstane-3,17-diol; Androstenediols; Androstenedione; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Male; Pregnanolone; Pregnenolone; Progesterone; Testis; Testosterone

1975
Changes in steroidogenesis in preovulatory rat ovaries induced to ovulate with pregnant mare serum gonadotropin.
    Endocrinology, 1978, Volume: 103, Issue:4

    Topics: 20-alpha-Dihydroprogesterone; Androstane-3,17-diol; Animals; Female; Gonadotropins, Equine; Isomerism; Ovary; Ovulation; Ovulation Induction; Pregnanediol; Pregnanolone; Progesterone; Rats; Sexual Maturation

1978
Metabolism of progesterone by rat ovarian tissue: influence of pregnant mare serum gonadotropin and prolactin.
    Biology of reproduction, 1975, Volume: 12, Issue:5

    Topics: Androstane-3,17-diol; Androstenedione; Androsterone; Animals; Chromatography, Thin Layer; Estrus; Female; Gonadotropins, Equine; Isomerism; Ovarian Follicle; Ovary; Ovulation; Pregnancy; Pregnanolone; Progesterone; Prolactin; Rats; Testosterone; Theca Cells

1975
Identification of two 5alpha-reduced pregnanes as major metabolites of progesterone in immature rat ovaries (1000 x g supernatant) in vitro.
    Endocrinology, 1976, Volume: 98, Issue:1

    Topics: Androstane-3,17-diol; Animals; Female; Ovary; Oxidation-Reduction; Oxidoreductases; Pregnanediol; Pregnanes; Pregnanolone; Progesterone; Rats

1976
Quantitative analysis of steroids and steroid glucuronides in the seminal vesicle fluid of feral spawning and feral and cultivated nonspawning African catfish, Clarias gariepinus.
    General and comparative endocrinology, 1988, Volume: 70, Issue:1

    Topics: Androstane-3,17-diol; Animals; Catfishes; Dihydrotestosterone; Etiocholanolone; Gas Chromatography-Mass Spectrometry; Glucuronates; Male; Pregnanolone; Reproduction; Semen; Steroids; Testosterone

1988
Role of brain cytochrome P450 in regulation of the level of anesthetic steroids in the brain.
    Molecular pharmacology, 1993, Volume: 44, Issue:5

    Topics: Androstane-3,17-diol; Anesthetics; Animals; Brain; Cytochrome P-450 Enzyme System; Hydroxylation; Male; Mice; Pituitary Gland; Pregnanolone; Prostate; Rats; Rats, Sprague-Dawley; Substrate Specificity

1993
Mating stimuli influence endogenous variations in the neurosteroids 3alpha,5alpha-THP and 3alpha-Diol.
    Journal of neuroendocrinology, 1999, Volume: 11, Issue:11

    Topics: Androgens; Androstane-3,17-diol; Animals; Brain; Corticosterone; Estrogens; Estrus; Female; Male; Organ Specificity; Physical Stimulation; Postpartum Period; Posture; Pregnancy; Pregnanolone; Rats; Rats, Long-Evans; Sexual Behavior, Animal; Touch

1999
5Beta,6beta-epoxy-17-oxoandrostan-3beta-yl acetate and 5beta,6beta-epoxy-20-oxopregnan-3beta-yl acetate.
    Acta crystallographica. Section C, Crystal structure communications, 2008, Volume: 64, Issue:Pt 5

    Topics: Androstane-3,17-diol; Molecular Structure; Pregnanolone; Steroids; X-Ray Diffraction

2008
Acute experimental autoimmune encephalomyelitis induces sex dimorphic changes in neuroactive steroid levels.
    Neurochemistry international, 2010, Volume: 56, Issue:1

    Topics: 20-alpha-Dihydroprogesterone; Acute Disease; Androstane-3,17-diol; Animals; Brain; Chromatography, Liquid; Dihydrotestosterone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Male; Mass Spectrometry; Multiple Sclerosis; Neurotransmitter Agents; Pregnanolone; Progesterone; Rats; Sex Characteristics; Testosterone

2010
Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans.
    Alcoholism, clinical and experimental research, 2010, Mar-01, Volume: 34, Issue:3

    Topics: Adult; Androstane-3,17-diol; Androsterone; Animals; Central Nervous System Depressants; Desoxycorticosterone; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Young Adult

2010
Improvement of neuronal bioenergetics by neurosteroids: implications for age-related neurodegenerative disorders.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:12 Pt A

    Topics: Adenosine Triphosphate; Aging; Androstane-3,17-diol; Animals; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Energy Metabolism; Estradiol; Estrone; Humans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neurodegenerative Diseases; Neurons; Neurotransmitter Agents; Oxygen Consumption; Pregnanolone; Progesterone; Reactive Oxygen Species; Superoxide Dismutase; Testosterone

2014
5α-Reduced neurosteroids sex-dependently reverse central prenatal programming of neuroendocrine stress responses in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jan-14, Volume: 35, Issue:2

    Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstane-3,17-diol; Animals; Female; Hypothalamo-Hypophyseal System; Interleukin-1beta; Male; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Pregnancy; Pregnancy Complications; Pregnanolone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sex Factors; Solitary Nucleus; Stress, Psychological

2015
Neuroactive Steroids and Affective Symptoms in Women Across the Weight Spectrum.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:6

    Topics: Adult; Affective Symptoms; Androstane-3,17-diol; Anorexia Nervosa; Anxiety; Body Mass Index; Cross-Sectional Studies; Depression; Female; Humans; Overweight; Pregnanolone; Progesterone; Psychiatric Status Rating Scales; Severity of Illness Index; Testosterone; Thinness

2018
Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals.
    International journal of molecular sciences, 2021, Nov-21, Volume: 22, Issue:22

    Topics: Androstane-3,17-diol; Animals; Brain; Chromatography; Dihydrotestosterone; Gastrointestinal Microbiome; Germ Cells; Gonadal Steroid Hormones; Male; Mice; Microbiota; Neurosteroids; Pregnanolone; Tandem Mass Spectrometry; Testosterone

2021