Page last updated: 2024-08-23

pregnanolone and 3-hydroxypregnan-3-one 3-sulfate

pregnanolone has been researched along with 3-hydroxypregnan-3-one 3-sulfate in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, RA; Axelson, M; Baillie, TA; Cronholm, T; Sjövall, J; Sjövall, K1
Azpeitia, E; Kubli-Garfias, C; Ponce-Monter, H; Villanueva-Tello, T1
Baillie, TA; Curstedt, T; Sjövall, J; Sjövall, K1
Farb, DH; Park-Chung, M; Wu, FS1
Farb, DH; Gibbs, TT; Malayev, AA; Park-Chung, M; Purdy, RH; Wu, FS1
Covey, DF; Nilsson, KR; Zorumski, CF1
Farb, DH; Gibbs, TT; Malayev, A1
Cascio, C; De Leo, G; Guarneri, M; Guarneri, P; Guarneri, R; Piccoli, F; Russo, D1
Bartle, E; Borkowski, B; Cameron, K; Fanelli, D; Gentile, L; Kahlson, M; Kangala, M; Kim, J; Pham, M; Pollard, B; Rhoads, S; Roark, R; Rocha, M1

Other Studies

9 other study(ies) available for pregnanolone and 3-hydroxypregnan-3-one 3-sulfate

ArticleYear
Stable isotope studies on steroid metabolism and kinetics: sulfates of 3 alpha-hydroxy-5 alpha-pregnane derivatives in human pregnancy.
    Steroids, 1990, Volume: 55, Issue:10

    Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Hydroxylation; Kinetics; Oxidation-Reduction; Pregnancy; Pregnanediol; Pregnanolone; Steroid 16-alpha-Hydroxylase; Sulfates

1990
Inhibition of noradrenaline release by 5 beta-progestins in cerebral cortex slices.
    Proceedings of the Western Pharmacology Society, 1983, Volume: 26

    Topics: Animals; Cerebral Cortex; Female; In Vitro Techniques; Norepinephrine; Pregnanediones; Pregnanolone; Rats

1983
Production rates and metabolism of sulphates of 3 beta-hydroxy-5 alpha-pregnane derivatives in pregnant women.
    Journal of steroid biochemistry, 1980, Volume: 13, Issue:12

    Topics: Deuterium; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Kinetics; Pregnancy; Pregnanediol; Pregnanes; Pregnanolone; Radioisotope Dilution Technique; Structure-Activity Relationship

1980
3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons.
    Molecular pharmacology, 1994, Volume: 46, Issue:1

    Topics: Animals; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Ion Channels; Isomerism; Neurons; Pregnanolone; Receptors, N-Methyl-D-Aspartate

1994
Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids.
    Molecular pharmacology, 1997, Volume: 52, Issue:6

    Topics: Animals; Arachidonic Acid; Binding Sites; Binding, Competitive; Cells, Cultured; Chick Embryo; Hippocampus; N-Methylaspartate; Neurons; Oxidation-Reduction; Polyamines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Structure-Activity Relationship; Xenopus laevis

1997
Neurosteroid analogues. 6. The synthesis and GABAA receptor pharmacology of enantiomers of dehydroepiandrosterone sulfate, pregnenolone sulfate, and (3alpha,5beta)-3-hydroxypregnan-20-one sulfate.
    Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14

    Topics: Animals; Cells, Cultured; Dehydroepiandrosterone Sulfate; GABA Modulators; Hippocampus; Neurons; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Stereoisomerism

1998
Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids.
    British journal of pharmacology, 2002, Volume: 135, Issue:4

    Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Models, Biological; Oocytes; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis

2002
A caspase-3-dependent pathway is predominantly activated by the excitotoxin pregnenolone sulfate and requires early and late cytochrome c release and cell-specific caspase-2 activation in the retinal cell death.
    Journal of neurochemistry, 2002, Volume: 83, Issue:6

    Topics: Animals; Apoptosis; Caspase 2; Caspase 3; Caspases; Cytochrome c Group; Enzyme Activation; Enzyme Inhibitors; Estradiol; In Situ Nick-End Labeling; In Vitro Techniques; Male; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina; Signal Transduction

2002
Neurosteroid binding to the amino terminal and glutamate binding domains of ionotropic glutamate receptors.
    Steroids, 2012, Volume: 77, Issue:7

    Topics: Binding Sites; Cloning, Molecular; Models, Molecular; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Receptors, Ionotropic Glutamate; Spectrometry, Fluorescence

2012