pregnanolone has been researched along with 20-alpha-dihydroprogesterone in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (37.50) | 18.7374 |
| 1990's | 9 (22.50) | 18.2507 |
| 2000's | 9 (22.50) | 29.6817 |
| 2010's | 6 (15.00) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Athey, B; Chen, GT; Gant, NF; Macdonald, PC; Milewich, L; Prough, RA; Schwarz, BE | 1 |
| Chen, GT; Gant, NF; Macdonald, PC; Milewich, L; Schwarz, BE | 1 |
| Gilles, PA; Karavolas, HJ; Lloyd, RV | 1 |
| Martini, L; Zanisi, M | 1 |
| Atkins, DT; Fleeger, JL; Harms, PG; Seamans, KW | 1 |
| Beyer, C; Bondani, A; Kubli-Garfias, C; Medrano-Conde, L | 1 |
| Eckstein, B; Lerner, N | 1 |
| Hodges, D; Karavolas, HJ; O'Brien, D | 1 |
| Holtermann, M; Lisboa, BP | 2 |
| Morrow, AL; Pace, JR; Paul, SM; Purdy, RH | 1 |
| Mannan, MA; O'Shaughnessy, PJ | 1 |
| Duleba, AJ; Kim, KS; Moon, YS; Yuen, BH | 1 |
| Collins, PM; Tsang, WN | 1 |
| Gilles, PA; Karavolas, HJ | 1 |
| Laumas, KR; Verma, U | 1 |
| Backstrom, T; de Lignieres, B; Dennerstein, L | 1 |
| Cooper, TB; Costa, E; Guidotti, A; Uzunov, DP | 1 |
| Driscoll, P; Schulz, PE; Steimer, T | 1 |
| Beck, CA; Murphy, LD; Wiebe, JP; Wolfe, M | 1 |
| Cavarretta, I; Magnaghi, V; Martini, L; Melcangi, RC; Piva, F | 1 |
| Bovolin, P; Cavarretta, I; D'Urso, D; Magnaghi, V; Martini, L; Melcangi, RC; Zucchi, I | 1 |
| Arici, A; Dombrowski, RA; MacDonald, PC; Marshburn, PB | 1 |
| Cavarretta, I; Ferraboschi, P; Magnaghi, V; Martini, L; Melcangi, RC | 1 |
| Frye, CA; Kehoe, P; Mallinson, K; McCormick, CM | 1 |
| Kim, HY; Reddy, DS; Rogawski, MA | 1 |
| Ortega, E; Ruiz, E; Torres, JM | 1 |
| Costa, E; Dong, E; Guidotti, A; Matsumoto, K; Pinna, G; Rasmusson, AM | 1 |
| Fisch, B; Galdor, M; Kaplan, B; Kinor, N; Maayan, R; Shinnar, N; Valevski, A; Weizman, A; Zeldich, E | 1 |
| Bianchi, R; Caruso, D; Cavaletti, G; Crippa, D; Garcia-Segura, LM; Lauria, G; Leonelli, E; Magnaghi, V; Melcangi, RC; Roglio, I | 1 |
| Frye, CA; Paris, JJ; Rhodes, ME | 1 |
| Higashi, T; Mukai, Y; Nagura, Y; Shimada, K | 1 |
| Brunton, PJ; Lachowicz, A; McKay, AJ; Ochedalski, T; Piastowska, A; Rebas, E; Russell, JA | 1 |
| Calza, L; Caruso, D; D'Intino, G; Garcia-Segura, LM; Giatti, S; Maschi, O; Melcangi, RC; Pesaresi, M | 1 |
| Frye, CA; Koonce, CJ; Walf, AA | 1 |
| do Rego, JL; Vaudry, D; Vaudry, H | 1 |
| Ball, BA; Berger, T; Conley, AJ; Legacki, EL; Scholtz, EL; Stanley, SD | 1 |
| Barton, BA; Deligiannidis, KM; Hall, JE; Jaitly, N; Kroll-Desrosiers, AR; Mo, S; Nguyen, HP; Rothschild, AJ; Shaffer, SA; Svenson, A | 1 |
| Burnham, WM; Wu, YV | 1 |
| Deligiannidis, KM; Dubuke, ML; Kroll-Desrosiers, AR; Shaffer, SA; Tan, Y | 1 |
2 review(s) available for pregnanolone and 20-alpha-dihydroprogesterone
| Article | Year |
|---|---|
The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders.
Topics: 20-alpha-Dihydroprogesterone; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Disease Models, Animal; Mice; Pregnanolone; Psychotic Disorders; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Social Isolation | 2001 |
Progesterone, 5a-dihydropogesterone and allopregnanolone's effects on seizures: A review of animal and clinical studies.
Topics: 20-alpha-Dihydroprogesterone; Animals; Anticonvulsants; Humans; Pregnanolone; Progesterone; Seizures | 2018 |
1 trial(s) available for pregnanolone and 20-alpha-dihydroprogesterone
| Article | Year |
|---|---|
Influence of route of administration on progesterone metabolism.
Topics: 20-alpha-Dihydroprogesterone; Administration, Intravaginal; Administration, Oral; Cross-Over Studies; Desoxycorticosterone; Female; Humans; Pregnanolone; Progesterone | 1995 |
37 other study(ies) available for pregnanolone and 20-alpha-dihydroprogesterone
| Article | Year |
|---|---|
Initiation of human parturition. VI. Identification and quantification of progesterone metabolites produced by the components of human fetal membranes.
Topics: 20-alpha-Dihydroprogesterone; Amnion; Chorion; Chromatography; Extraembryonic Membranes; Female; Humans; Labor Onset; Labor, Obstetric; NADP; Pregnancy; Pregnanediones; Pregnanolone; Progesterone | 1977 |
Initiation of human parturition. IX. Progesterone metabolism by placentas of early and late human gestation.
Topics: 20-alpha-Dihydroprogesterone; 20-Hydroxysteroid Dehydrogenases; Female; Gestational Age; Humans; NADP; Placenta; Pregnancy; Pregnanediones; Pregnanolone; Progesterone | 1978 |
Uptake and metabolism of female sex steroids by isolated small neurons and other cell fractions from the rat medial basal hypothalamus.
Topics: 20-alpha-Dihydroprogesterone; Animals; Cell Separation; Cerebral Cortex; Estradiol; Female; Gonadotropin-Releasing Hormone; History, 18th Century; Hypothalamus; Hypothalamus, Middle; Neuroglia; Neurons; Pregnanolone; Progesterone; Rats; Synaptosomes | 1979 |
Interaction of oestrogen and of physiological progesterone metabolites in the control of gonadotropin secretion.
Topics: 20-alpha-Dihydroprogesterone; Animals; Castration; Drug Implants; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Median Eminence; Pituitary Gland, Anterior; Pregnanolone; Progesterone; Rats | 1979 |
Serum levels of progesterone, 5 alpha-dihydroprogesterone and hydroxy-5 alpha-pregnanones in the prepartum and postpartum equine.
Topics: 20-alpha-Dihydroprogesterone; Animals; Female; Horses; Isomerism; Labor Onset; Labor, Obstetric; Pregnancy; Pregnancy, Animal; Pregnanes; Pregnanolone; Progesterone; Time Factors | 1979 |
In vitro inhibition of rat uterine contractility induced by 5 alpha and 5 beta progestins.
Topics: 20-alpha-Dihydroprogesterone; Animals; Diestrus; Dose-Response Relationship, Drug; Female; Isomerism; Pregnancy; Pregnanediol; Pregnanediones; Pregnanes; Pregnanolone; Progesterone; Progestins; Rats; Stereoisomerism; Structure-Activity Relationship; Uterine Contraction | 1979 |
Changes in steroidogenesis in preovulatory rat ovaries induced to ovulate with pregnant mare serum gonadotropin.
Topics: 20-alpha-Dihydroprogesterone; Androstane-3,17-diol; Animals; Female; Gonadotropins, Equine; Isomerism; Ovary; Ovulation; Ovulation Induction; Pregnanediol; Pregnanolone; Progesterone; Rats; Sexual Maturation | 1978 |
Uptake of (3H)progesterone and (3H)5alpha-dihydroprogesterone by rat tissues in vivo and analysis of accumulated radioactivity: accumulation of 5alpha-dihydroprogesterone by pituitary and hypothalamic tissues.
Topics: 20-alpha-Dihydroprogesterone; Adrenalectomy; Animals; Castration; Chromatography, Thin Layer; Female; Hypothalamus; Hypothalamus, Middle; Pituitary Gland; Pregnanolone; Progesterone; Radioisotope Dilution Technique; Rats; Tritium; Uterus | 1976 |
Metabolism of progesterone in uterine tissue of non-pregnant rats in vitro.
Topics: 20-alpha-Dihydroprogesterone; Allyl Compounds; Animals; Female; Pregnanediol; Pregnanes; Pregnanolone; Pregnenes; Progesterone; Rats; Uterus | 1976 |
Metabolism of 20beta-hydroxy-4-pregnen-3-one in uterine tissue of non-pregnant rats in vitro.
Topics: 20-alpha-Dihydroprogesterone; Animals; Female; Isomerism; Pregnanediol; Pregnanes; Pregnanolone; Pregnenes; Progesterone; Rats; Uterus | 1976 |
Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites.
Topics: 20-alpha-Dihydroprogesterone; Animals; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Proteins; Pregnanolone; Rats; Receptors, GABA-A; Steroids; Structure-Activity Relationship; Synaptosomes | 1990 |
Ovarian steroid metabolism during post-natal development in the normal mouse and in the adult hypogonadal (hpg) mouse.
Topics: 20-alpha-Dihydroprogesterone; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aging; Androstenedione; Animals; Female; Hypogonadism; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Ovary; Pregnanolone; Progesterone | 1988 |
Alterations of 20 alpha-hydroxysteroid dehydrogenase activity in cultured rat granulosa cells by follicle-stimulating hormone and testosterone.
Topics: 20-alpha-Dihydroprogesterone; 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Animals; Cells, Cultured; Cyanoketone; Dose-Response Relationship, Drug; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Pregnanediol; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Stereoisomerism; Testosterone | 1985 |
A quantitative assessment of the gametogenic and androgenic properties of testicular steroids in hypophysectomized rats.
Topics: 20-alpha-Dihydroprogesterone; Animals; Body Weight; Cell Count; Hypophysectomy; Isomerism; Male; Organ Size; Pregnanolone; Progesterone; Rats; Rats, Inbred Strains; Seminiferous Tubules; Spermatogenesis; Testis; Testosterone | 1985 |
Effect on ovulation of 20 alpha-hydroxy-4-pregnen-3-one and its 5 alpha-reduced metabolites in immature rats treated with pregnant mare serum gonadotrophin.
Topics: 20-alpha-Dihydroprogesterone; Animals; Dose-Response Relationship, Drug; Female; Gonadotropins, Equine; Ovulation; Pregnanediol; Pregnanolone; Progesterone; Rats; Sexual Maturation | 1981 |
Progesterone biotransformation by the pituitary and hypothalamus of rabbit.
Topics: 20-alpha-Dihydroprogesterone; Animals; Biotransformation; Endometrium; Female; Hypothalamus; Myometrium; Pituitary Gland; Pregnanediones; Pregnanolone; Progesterone; Rabbits; Subcellular Fractions | 1981 |
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.
Topics: 20-alpha-Dihydroprogesterone; Adrenalectomy; Animals; Brain; Castration; Fluoxetine; GABA Modulators; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Imipramine; Male; Paroxetine; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley | 1996 |
Brain metabolism of progesterone, coping behaviour and emotional reactivity in male rats from two psychogenetically selected lines.
Topics: 20-alpha-Dihydroprogesterone; Adaptation, Psychological; Animals; Anxiety; Brain; Corticosterone; Emotions; Environment; Exploratory Behavior; Frontal Lobe; Male; Pregnanolone; Progesterone; Prolactin; Rats | 1997 |
Acute, nongenomic actions of the neuroactive gonadal steroid, 3 alpha-hydroxy-4-pregnen-20-one (3 alpha HP), on FSH release in perifused rat anterior pituitary cells.
Topics: 20-alpha-Dihydroprogesterone; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Agonists; Cells, Cultured; Estradiol; Female; Follicle Stimulating Hormone; GABA Modulators; Gonadotropin-Releasing Hormone; Ionophores; Perfusion; Pituitary Gland, Anterior; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Serum Albumin; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases | 1997 |
Age-induced decrease of glycoprotein Po and myelin basic protein gene expression in the rat sciatic nerve. Repair by steroid derivatives.
Topics: 20-alpha-Dihydroprogesterone; Aging; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Gene Expression Regulation; Male; Myelin Basic Protein; Myelin P0 Protein; Oligodendroglia; Pregnanolone; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve | 1998 |
Progesterone derivatives are able to influence peripheral myelin protein 22 and P0 gene expression: possible mechanisms of action.
Topics: 20-alpha-Dihydroprogesterone; Aging; Animals; Blotting, Northern; Cells, Cultured; Gene Expression Regulation; Male; Myelin P0 Protein; Myelin Proteins; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schwann Cells; Sciatic Nerve | 1999 |
Progesterone metabolism in human endometrial stromal and gland cells in culture.
Topics: 20-alpha-Dihydroprogesterone; Cells, Cultured; Chromatography, Thin Layer; Endometrium; Estradiol; Female; Humans; Pregnanolone; Progesterone; Stromal Cells; Time Factors | 1999 |
Interactions between type 1 astrocytes and LHRH-secreting neurons (GT1-1 cells): modification of steroid metabolism and possible role of TGFbeta1.
Topics: 20-alpha-Dihydroprogesterone; 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Astrocytes; Cells, Cultured; Coculture Techniques; Dihydrotestosterone; Etiocholanolone; Gonadotropin-Releasing Hormone; Neurons; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Steroids; Testosterone; Transforming Growth Factor beta | 1999 |
Central allopregnanolone is increased in rat pups in response to repeated, short episodes of neonatal isolation.
Topics: 20-alpha-Dihydroprogesterone; Animals; Animals, Newborn; Brain; Female; Osmolar Concentration; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reference Values; Social Isolation; Stress, Psychological | 2000 |
Neurosteroid withdrawal model of perimenstrual catamenial epilepsy.
Topics: 20-alpha-Dihydroprogesterone; Adult; Animals; Behavior, Animal; Disease Models, Animal; Disease Susceptibility; Epilepsy; Female; Finasteride; Gonadotropins, Equine; Humans; Menstrual Cycle; Pentylenetetrazole; Pregnanolone; Progesterone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome | 2001 |
Effects of CRH and ACTH administration on plasma and brain neurosteroid levels.
Topics: 20-alpha-Dihydroprogesterone; Adrenocorticotropic Hormone; Animals; Blood; Brain; Corticotropin-Releasing Hormone; Female; Male; Pregnanolone; Progesterone; Rats; Rats, Wistar; Sex Characteristics | 2001 |
Influence of 17beta-estradiol on the synthesis of reduced neurosteroids in the brain (in vivo) and in glioma cells (in vitro): possible relevance to mental disorders in women.
Topics: 20-alpha-Dihydroprogesterone; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Analysis of Variance; Animals; Cerebral Cortex; Enzyme Inhibitors; Estradiol; Female; Glioma; Hormones; Humans; Hypothalamus; Mice; Mood Disorders; Neurons; Oxidation-Reduction; Pregnanolone; Progesterone; Rats; RNA, Messenger; Tumor Cells, Cultured | 2004 |
Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: a multimodal analysis.
Topics: 20-alpha-Dihydroprogesterone; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Down-Regulation; Male; Myelin Proteins; Neural Conduction; Neuroprotective Agents; Pain Threshold; Peripheral Nerves; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recovery of Function; RNA, Messenger; Sensory Receptor Cells; Skin; Sodium-Potassium-Exchanging ATPase; Treatment Outcome | 2007 |
Engaging in paced mating, but neither exploratory, anti-anxiety, nor social behavior, increases 5alpha-reduced progestin concentrations in midbrain, hippocampus, striatum, and cortex.
Topics: 20-alpha-Dihydroprogesterone; Animals; Anxiety; Brain; Cerebral Cortex; Corpus Striatum; Estradiol; Exploratory Behavior; Female; Hippocampus; Mesencephalon; Pregnanolone; Progestins; Radioimmunoassay; Random Allocation; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Social Behavior | 2007 |
Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor, finasteride, on rat brain neurosteroid levels and metabolism.
Topics: 20-alpha-Dihydroprogesterone; 5-alpha Reductase Inhibitors; Animals; Brain Chemistry; Calibration; Desoxycorticosterone; Enzyme Inhibitors; Finasteride; Indicators and Reagents; Injections, Intraperitoneal; Male; Neurotransmitter Agents; Pregnanolone; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Steroids | 2008 |
Central opioid inhibition of neuroendocrine stress responses in pregnancy in the rat is induced by the neurosteroid allopregnanolone.
Topics: 20-alpha-Dihydroprogesterone; Adrenocorticotropic Hormone; Analgesics, Opioid; Analysis of Variance; Anesthetics; Animals; Chromatography, Thin Layer; Corticosterone; Corticotropin-Releasing Hormone; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Finasteride; Hypothalamo-Hypophyseal System; Interleukin-1beta; Neural Inhibition; Neurons; Oxidoreductases; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Progestins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Physiological; Time Factors | 2009 |
Acute experimental autoimmune encephalomyelitis induces sex dimorphic changes in neuroactive steroid levels.
Topics: 20-alpha-Dihydroprogesterone; Acute Disease; Androstane-3,17-diol; Animals; Brain; Chromatography, Liquid; Dihydrotestosterone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Male; Mass Spectrometry; Multiple Sclerosis; Neurotransmitter Agents; Pregnanolone; Progesterone; Rats; Sex Characteristics; Testosterone | 2010 |
Role of pregnane xenobiotic receptor in the midbrain ventral tegmental area for estradiol- and 3α,5α-THP-facilitated lordosis of female rats.
Topics: 20-alpha-Dihydroprogesterone; Animals; Anxiety; Estradiol; Female; Interpersonal Relations; Motor Activity; Pregnane X Receptor; Pregnanolone; Progesterone; Rats; Rats, Long-Evans; Receptors, Steroid; Sexual Behavior, Animal; Ventral Tegmental Area | 2014 |
The non-benzodiazepine anxiolytic drug etifoxine causes a rapid, receptor-independent stimulation of neurosteroid biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Animals; Anti-Anxiety Agents; Bicuculline; Complex Mixtures; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Gene Expression; Hypothalamus; Isoquinolines; Male; Neuropeptides; Oxazines; Peptide Fragments; Pregnanolone; Progesterone; Rana esculenta; Receptors, GABA-A; Tissue Culture Techniques | 2015 |
The dynamic steroid landscape of equine pregnancy mapped by mass spectrometry.
Topics: 20-alpha-Dihydroprogesterone; Animals; Biomarkers; Chromatography, Liquid; Corpus Luteum; Female; Horses; Placenta; Pregnancy; Pregnancy, Animal; Pregnanolone; Pregnenolone; Progesterone; Steroids; Tandem Mass Spectrometry | 2016 |
Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
Topics: 20-alpha-Dihydroprogesterone; Adult; Case-Control Studies; Depression, Postpartum; Desoxycorticosterone; Female; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Peripartum Period; Pregnancy; Pregnanolone; Progesterone; Receptors, GABA-A; Risk Factors; Steroids | 2016 |
Longitudinal proneuroactive and neuroactive steroid profiles in medication-free women with, without and at-risk for perinatal depression: A liquid chromatography-tandem mass spectrometry analysis.
Topics: 20-alpha-Dihydroprogesterone; Adult; Anxiety; Chromatography, Liquid; Depression; Depression, Postpartum; Depressive Disorder; Desoxycorticosterone; Female; Humans; Longitudinal Studies; Neurosteroids; Parturition; Pregnancy; Pregnanolone; Pregnenolone; Prenatal Care; Progesterone; Prospective Studies; Risk Factors; Tandem Mass Spectrometry | 2020 |