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prednisolone 21-3-sulfobenzoate and prednisolone

prednisolone 21-3-sulfobenzoate has been researched along with prednisolone in 16 studies

*Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states. [MeSH]

*Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states. [MeSH]

Compound Research Comparison

Studies
(prednisolone 21-3-sulfobenzoate)
Trials
(prednisolone 21-3-sulfobenzoate)
Recent Studies (post-2010)
(prednisolone 21-3-sulfobenzoate)
Studies
(prednisolone)
Trials
(prednisolone)
Recent Studies (post-2010) (prednisolone)
177034,4143,3027,141

Protein Interaction Comparison

ProteinTaxonomyprednisolone 21-3-sulfobenzoate (IC50)prednisolone (IC50)
Glucocorticoid receptorHomo sapiens (human)0.0278
Progesterone receptorHomo sapiens (human)2.08
Glucocorticoid receptorRattus norvegicus (Norway rat)0.0565
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.016
Mineralocorticoid receptor Homo sapiens (human)0.0322
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.016
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.016
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.016

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's4 (25.00)18.2507
2000's8 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bustan, H; Slor, H1
Jewell, DP1
Atienza, P; Brion, N; Carbon, C; Pibarot, ML; Robin, P1
Berghouse, L; English, J; Lennard-Jones, JE; Macrae, FA; McIntyre, PB1
Axon, AT; Dickinson, RJ; Dixon, MF; Hamilton, I; Pinder, IF; Ruddell, WS1
Gray, RS; Luman, W; Palmer, KR; Pendek, R1
Chosidow, O; Delchier, JC; Diquet, B; Dutreuil, C; Herson, S; Revuz, J; Rollin, C1
Bernard, P; Chosidow, O; Delaporte, E; Herson, S; Joly, P; Lebrun-Vignes, B; Prost, C; Roujeau, JC; Vaillant, L1
Coriat, F; Delmas, PD; Olivieri-Apicella, N1
Monk, BE; Skipper, D1
Balan, K; Binnie, JA; Cameron, EA; Middleton, SJ; Skerratt, SA; Solanki, C; Swift, A1
Decosta, P; Deslandes, B; Rancé, F1
Darlow, SJ; Mandal, A; Mayberry, JF; Pick, B; Robinson, RJ; Thomas, T1
Hanauer, SB; Sparrow, M1
Beales, I; Dickinson, R; Dronfield, M; Pugh, S; Rhodes, JM; Robinson, R; Speirs, CJ; Wilkinson, P; Wilkinson, SP1
Annabel, M; Emmanuelle, L; Fabienne, L; Gérard, L; Hubert, L; Jacques, C1

Reviews

1 review(s) available for prednisolone 21-3-sulfobenzoate and prednisolone

ArticleYear
COLAL-PRED Alizyme.
    Current opinion in investigational drugs (London, England : 2000), 2004, Volume: 5, Issue:11

    Topics: Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Inflammatory Bowel Diseases; Prednisolone; Structure-Activity Relationship

2004

Trials

7 trial(s) available for prednisolone 21-3-sulfobenzoate and prednisolone

ArticleYear
[Comparative serum pharmacokinetics of prednisone and prednisolone methylsulfobenzoate after oral administration].
    Presse medicale (Paris, France : 1983), 1988, Apr-02, Volume: 17, Issue:12

    Topics: Administration, Oral; Adult; Clinical Trials as Topic; Humans; Male; Prednisolone; Prednisone; Therapeutic Equivalency

1988
Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis.
    Gut, 1985, Volume: 26, Issue:8

    Topics: Adult; Aged; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Enema; Female; Humans; Intestinal Absorption; Male; Middle Aged; Prednisolone

1985
A comparison of prednisolone enemas with low-dose oral prednisolone in the treatment of acute distal ulcerative colitis.
    Diseases of the colon and rectum, 1984, Volume: 27, Issue:11

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Colitis, Ulcerative; Enema; Female; Humans; Male; Middle Aged; Prednisolone; Prospective Studies

1984
Comparative study of availability of prednisolone after intestinal infusion of prednisolone metasulfobenzoate and prednisone.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:4

    Topics: Adult; Analysis of Variance; Biological Availability; Humans; Instillation, Drug; Intestinal Absorption; Jejunum; Male; Prednisolone; Prednisone; Reference Values

1993
Prednisone is more effective than prednisolone metasulfobenzoate in the treatment of bullous pemphigoid.
    Archives of dermatology, 1999, Volume: 135, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Female; Glucocorticoids; Humans; Male; Middle Aged; Pemphigoid, Bullous; Prednisolone; Retrospective Studies; Treatment Outcome

1999
Oral prednisolone metasulphobenzoate in the treatment of active ulcerative colitis.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:5

    Topics: Administration, Oral; Anti-Inflammatory Agents; Colitis, Ulcerative; Female; Humans; Male; Middle Aged; Prednisolone; Radionuclide Imaging; Treatment Outcome

2003
Clinical trial: oral prednisolone metasulfobenzoate (Predocol) vs. oral prednisolone for active ulcerative colitis.
    Alimentary pharmacology & therapeutics, 2008, Feb-01, Volume: 27, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Chi-Square Distribution; Colitis, Ulcerative; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prednisolone; Pulse Therapy, Drug; Statistics, Nonparametric; Treatment Outcome

2008

Other Studies

8 other study(ies) available for prednisolone 21-3-sulfobenzoate and prednisolone

ArticleYear
Effects of prednisolone metasulfabenzoate on the induction of DNase II in comparison to alkaline phosphatase and acid phosphatase activities in cultures of HeLa S3 cells.
    Steroids, 1976, Volume: 27, Issue:6

    Topics: Acid Phosphatase; Alkaline Phosphatase; Deoxyribonucleases; Dose-Response Relationship, Drug; Enzyme Induction; HeLa Cells; Prednisolone; Solubility; Time Factors

1976
The new steroids: clinical experience in ulcerative colitis.
    The Mount Sinai journal of medicine, New York, 1990, Volume: 57, Issue:5

    Topics: Administration, Topical; Androstadienes; Anti-Inflammatory Agents; Beclomethasone; Betamethasone Valerate; Budesonide; Colitis, Ulcerative; Fluticasone; Glucocorticoids; Humans; Hydrocortisone; Prednisolone; Pregnenediones

1990
Prednisolone metasulphobenzoate foam retention enemas suppress the hypothalamo-pituitary-adrenal axis.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:2

    Topics: Administration, Rectal; Adult; Aged; Blood Glucose; Cortodoxone; Enema; Female; Homeostasis; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Insulin; Intestinal Absorption; Male; Middle Aged; Pituitary-Adrenal System; Prednisolone; Proctitis; Pyridines; Radioimmunoassay; Triglycerides

1994
[Acceptability and tolerance of prednisolone metasulfobenzoate in orally dispersing tablet].
    Presse medicale (Paris, France : 1983), 2001, Apr-21, Volume: 30, Issue:15

    Topics: Humans; Patient Satisfaction; Prednisolone; Tablets

2001
Allergy to topical corticosteroids in inflammatory bowel disease.
    Gut, 2003, Volume: 52, Issue:4

    Topics: Administration, Rectal; Anti-Inflammatory Agents; Crohn Disease; Drug Hypersensitivity; Glucocorticoids; Humans; Male; Middle Aged; Prednisolone; Treatment Failure

2003
[Acceptability and tolerance of prednisolone metasulfobenzoate in orally dispersing tablets in 2 to 12-years-old children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2004, Volume: 11, Issue:9

    Topics: Child; Child, Preschool; Female; Humans; Male; Patient Compliance; Patient Satisfaction; Prednisolone; Tablets

2004
The short-term effects of Eudragit-L-coated prednisolone metasulphobenzoate (Predocol) on bone formation and bone mineral density in acute ulcerative colitis.
    European journal of gastroenterology & hepatology, 2004, Volume: 16, Issue:11

    Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Bone Density; Colitis, Ulcerative; Delayed-Action Preparations; Drug Compounding; Female; Humans; Longitudinal Studies; Male; Middle Aged; Osteocalcin; Osteogenesis; Polymethacrylic Acids; Prednisolone; Treatment Outcome

2004
[Treatment of 2 cases of kerions with griseofulvin and oral steroids].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2009, Volume: 16, Issue:11

    Topics: Abscess; Administration, Oral; Adolescent; Anti-Inflammatory Agents; Antifungal Agents; Child; Dermatomycoses; Diagnosis, Differential; Drug Therapy, Combination; Female; Griseofulvin; Humans; Male; Prednisolone; Tinea Capitis; Tinea Favosa; Vulvar Diseases

2009