pre 084 has been researched along with vanoxerine in 4 studies
| Studies (pre 084) | Trials (pre 084) | Recent Studies (post-2010) (pre 084) | Studies (vanoxerine) | Trials (vanoxerine) | Recent Studies (post-2010) (vanoxerine) |
|---|---|---|---|---|---|
| 116 | 0 | 73 | 556 | 5 | 93 |
| 116 | 0 | 73 | 28 | 0 | 20 |
| Protein | Taxonomy | pre 084 (IC50) | vanoxerine (IC50) |
|---|---|---|---|
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.46 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.0103 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 3.84 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.0969 | |
| Small conductance calcium-activated potassium channel protein 2 | Rattus norvegicus (Norway rat) | 0.073 | |
| Small conductance calcium-activated potassium channel protein 3 | Rattus norvegicus (Norway rat) | 0.073 | |
| Small conductance calcium-activated potassium channel protein 1 | Rattus norvegicus (Norway rat) | 0.073 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.1485 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.022 | |
| Transporter | Rattus norvegicus (Norway rat) | 0.114 | |
| Mu-type opioid receptor | Homo sapiens (human) | 3.53 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 2.14 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoffman, BT; Katz, JL; Kopajtic, T; Newman, AH | 1 |
| Bowen, WD; Cao, J; George, C; Husbands, SM; Katz, JL; Kopajtic, T; Kulkarni, SS; Newman, AH; Williams, W | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
4 other study(ies) available for pre 084 and vanoxerine
| Article | Year |
|---|---|
2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.
Topics: Algorithms; Binding, Competitive; Carrier Proteins; Databases, Factual; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship; Radioligand Assay; Reproducibility of Results; Software | 2000 |
Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
Topics: Animals; Binding, Competitive; Brain; Cocaine-Related Disorders; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Receptors, sigma; Structure-Activity Relationship | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |