Protein | Taxonomy | pre 084 (IC50) | resveratrol (IC50) |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
M18 aspartyl aminopeptidase | Plasmodium falciparum 3D7 | | 2.242 |
Vif | Human immunodeficiency virus 1 | | 25.31 |
DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | | 25.31 |
Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | | 0.75 |
Amyloid-beta precursor protein | Homo sapiens (human) | | 2.6 |
Cytochrome P450 1A2 | Homo sapiens (human) | | 3 |
Prostaglandin G/H synthase 1 | Ovis aries (sheep) | | 2.025 |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | | 2.312 |
Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | | 0.0589 |
Cytochrome P450 3A4 | Homo sapiens (human) | | 0.6 |
Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | | 0.685 |
DNA polymerase alpha catalytic subunit | Homo sapiens (human) | | 3.3 |
Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | | 4.9 |
Aromatase | Homo sapiens (human) | | 0.96 |
Cytochrome P450 2C9 | Homo sapiens (human) | | 7 |
Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | | 0.685 |
Tyrosinase | Homo sapiens (human) | | 5.35 |
Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | | 1.3972 |
Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | | 2.5 |
Amine oxidase [flavin-containing] A | Homo sapiens (human) | | 2.4945 |
Prostaglandin G/H synthase 1 | Homo sapiens (human) | | 0.8517 |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | | 2.312 |
Amine oxidase [flavin-containing] B | Homo sapiens (human) | | 5.01 |
Dipeptidyl peptidase 4 | Homo sapiens (human) | | 0.0006 |
Cytochrome P450 2C19 | Homo sapiens (human) | | 3 |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | | 1.672 |
Prostaglandin G/H synthase 2 | Ovis aries (sheep) | | 3.49 |
Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | | 2.5 |
Transcription factor p65 | Homo sapiens (human) | | 2.5 |
Cytochrome P450 1B1 | Homo sapiens (human) | | 1.4 |
Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | | 1.63 |
large T antigen | Betapolyomavirus macacae | | 26.2 |
Authors | Studies |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
Del Valle, J; Mancuso, R; Morell, M; Navarro, X; Osta, R; Pallás, M | 1 |
Article | Year |
Chemical genetics reveals a complex functional ground state of neural stem cells.Nature chemical biology, 2007, Volume: 3, Issue:5
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.Nature chemical biology, 2009, Volume: 5, Issue:10
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G⁹³A ALS mice: overlapping effects or limited therapeutic opportunity?Orphanet journal of rare diseases, 2014, May-21, Volume: 9Topics: Adenylate Kinase; Amyotrophic Lateral Sclerosis; Animals; Drug Synergism; Mice; Mice, Transgenic; Morpholines; Neural Conduction; Phosphorylation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Resveratrol; Rotarod Performance Test; Sigma-1 Receptor; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2014 |