pre 084 has been researched along with pyrilamine in 1 studies
| Studies (pre 084) | Trials (pre 084) | Recent Studies (post-2010) (pre 084) | Studies (pyrilamine) | Trials (pyrilamine) | Recent Studies (post-2010) (pyrilamine) |
|---|---|---|---|---|---|
| 116 | 0 | 73 | 1,860 | 26 | 116 |
| Protein | Taxonomy | pre 084 (IC50) | pyrilamine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.13 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.976 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.3 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.997 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.13 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.0126 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.047 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0166 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 2.788 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.879 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.1 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.558 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
1 other study(ies) available for pre 084 and pyrilamine
| Article | Year |
|---|---|
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |