pre 084 has been researched along with piperidines in 9 studies
| Studies (pre 084) | Trials (pre 084) | Recent Studies (post-2010) (pre 084) | Studies (piperidines) | Trials (piperidines) | Recent Studies (post-2010) (piperidines) |
|---|---|---|---|---|---|
| 116 | 0 | 73 | 40,235 | 5,221 | 14,545 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baeyens, JM; Cobos, EJ; Del Pozo, E | 1 |
| Kapai, NA; Popova, OV; Rogozin, PD; Skrebitsky, VG; Solntseva, EI | 1 |
| Chen, L; Hong, J; Sha, S; Wang, C; Yin, J; Zhou, L | 1 |
| Maurice, T | 1 |
| Collina, S; Corana, F; Curti, D; Maggi, L; Mannucci, B; Marra, A; Peviani, M; Rossi, D | 1 |
| Bigogno, C; Canta, A; Cavaletti, G; Collina, S; Corbo, M; Curti, D; Dondio, G; Malacrida, A; Marra, A; Oggioni, N; Peviani, M; Pignataro, L; Rossi, D | 1 |
| Luedtke, RR; Mach, RH; Malik, M; Rangel-Barajas, C | 1 |
| Bezprozvanny, IB; Bol'shakova, AV; Gainullina, AN; Kraskovskaya, NA; Kukanova, EO; Vlasova, OL | 1 |
| Cortés-Montero, E; Garzón, J; Rodríguez-Muñoz, M; Sánchez-Blázquez, P | 1 |
9 other study(ies) available for pre 084 and piperidines
| Article | Year |
|---|---|
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Binding, Competitive; Brain; Dextromethorphan; Drug Interactions; Ethylenediamines; Guinea Pigs; Haloperidol; Ligands; Male; Morpholines; Neurons; Phenazocine; Phenytoin; Piperazines; Piperidines; Progesterone; Propylamines; Receptors, sigma; Synaptic Transmission | 2005 |
The involvement of sigma1 receptors in donepezil-induced rescue of hippocampal LTP impaired by beta-amyloid peptide.
Topics: Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; Cholinesterase Inhibitors; Donepezil; Haloperidol; Indans; Long-Term Potentiation; Male; Morpholines; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, sigma | 2014 |
Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anisoles; Astrocytes; Cell Death; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Morpholines; Neuroprotective Agents; Parkinson Disease, Secondary; Pars Compacta; Phenols; Phosphorylation; Piperidines; Propylamines; Psychomotor Performance; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Signal Transduction; Vesicular Monoamine Transport Proteins | 2015 |
Protection by sigma-1 receptor agonists is synergic with donepezil, but not with memantine, in a mouse model of amyloid-induced memory impairments.
Topics: Amyloid beta-Peptides; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Drug Synergism; Excitatory Amino Acid Antagonists; Furans; Indans; Male; Memantine; Memory Disorders; Mice; Morpholines; Neuroprotective Agents; Peptide Fragments; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor | 2016 |
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists.
Topics: Animals; Biphenyl Compounds; Brain; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Mice; Morpholines; Piperidines; Receptors, sigma; Sigma-1 Receptor; Spectrometry, Mass, Electrospray Ionization; Spinal Cord | 2016 |
Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist.
Topics: Biphenyl Compounds; Central Nervous System Diseases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Morpholines; Neuroprotective Agents; Piperidines; Receptors, sigma; Sigma-1 Receptor; Structure-Activity Relationship | 2016 |
The effect of the sigma-1 receptor selective compound LS-1-137 on the DOI-induced head twitch response in mice.
Topics: Acetanilides; Amphetamines; Animals; Head Movements; Male; Mice; Mice, Inbred DBA; Morpholines; Piperidines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, sigma; Sigma-1 Receptor | 2016 |
Neuroprotective Effect of σ1-Receptors on the Cell Model of Huntington's Disease.
Topics: Animals; Anisoles; Calcium; Cerebral Cortex; Corpus Striatum; Dendritic Spines; Gene Expression; Homeostasis; Huntington Disease; Male; Mice; Models, Biological; Morpholines; Neurons; Piperidines; Primary Cell Culture; Propylamines; Receptors, sigma; RNA, Small Interfering; Sigma-1 Receptor; Synapses; Synaptic Transmission; Transduction, Genetic | 2017 |
Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice.
Topics: Animals; Animals, Outbred Strains; Antimanic Agents; Cyclopropanes; Dizocilpine Maleate; Drug Interactions; Glycogen Synthase Kinase 3 beta; Mice; Mice, Knockout; Morpholines; Motor Activity; Nerve Tissue Proteins; Piperidines; Protein Kinase Inhibitors; Receptors, sigma | 2018 |